Clinical trials: Opacity
Graft Rejection
Pathogenetic Risk Factors for Corneal Graft Rejection
There are many predictors that may influence the development of corneal graft rejection after penetrating keratoplasty. In our study investigators analysed the results of keratoplasty and the risk factors for graft rejection.
- Trial name
- NCT06281587
- Testing
- penetrating keratoplasty
- Where
- Russia
- Volunteers
- 93 people
- Sponsor
- The S.N. Fyodorov Eye Microsurgery State Institution
Cataract, Healthy
Test of QLS Device to Detect Early Cataracts
This study will test the reliability of an instrument called the Quasi Elastic Laser Scattering Device (QLS) in detecting early changes in cataract formation. Surgery is currently the only treatment for cataracts.
- Trial name
- NCT00001617
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Corneal Opacity
Characteristics of Trachomatous Corneal Opacity in Fayoum University Hospital
The purpose of this study is to assess the characteristics of trachomatous corneal opacity in patients with signs of trachoma using Anterior segment Optic coherence tomography and Pentacam
- Trial name
- Trachoma (NCT06000150)
- Testing
- Corneal topography
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Omar Said
Corneal Opacities
Corneal Opacities in Children
A prospective observational study on corneal opacities in infants and children (1 month to 18 years old) will be conducted at CHLA. Most of these cases will be due to congenital corneal opacity (e.g.
- Trial name
- OCT (NCT02117323)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Oregon Health and Science University
Acute Lymphoblastic Leukemia, Bone Density Increased
Effects of Exercises on Total Body Health in Children With Acute Lymphoblastic Leukemia
In recent years, the survival of patients has increased with the success of leukemia treatment in children. However, according to the treatment modalities applied, complications such as changes in body composition such as…
- Trial name
- NCT04015882
- Testing
- Exercise therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Congenital Cataract
Congenital Cataract Morphological Classifications
Photography is considered as one of the most important means to promote evidence-based medical practice in pediatric ophthalmology.This study is to investigate the feasibility of congenital cataract morphological classifications…
- Trial name
- NCT02748031
- Testing
- slit-lamp-adapted anterior segmental photography
- Where
- China
- Volunteers
- 1,050 people
- Sponsor
- Sun Yat-sen University
Cataract, Congenital Anomaly
Studies of Families With Hereditary Cataracts
The objective of this study is to discover the genes responsible for the development of hereditary cataracts in families. A cataract is clouding of the lens of the eye that obstructs the passage of light and may impair vision.
- Trial name
- NCT00001609
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- National Eye Institute (NEI)
Purpura, Thrombocytopaenic, Idiopathic
LENS - Long-term Eltrombopag Observational Study
A long term observational ocular safety study in adults who have received study medication (either active drug or placebo) in a phase II or III clinical study evaluating eltrombopag.
- Trial name
- LENS (NCT00643929)
- Testing
- Eltrombopag
- Where
- 71 sites in United States, Australia and 19 more
- Volunteers
- 164 people
- Sponsor
- GlaxoSmithKline
Lymph Node Metastases, Non-small Cell Lung Cancer Stage I
Mediastinal Staging Accuracy of a Selective Lymphadenectomy Strategy in Early Stage NSCLC (ECTOP-1003)
This is a clinical trial from Eastern Cooperative Thoracic Oncology Project (ECTOP), numbered as ECTOP-1003. Systemic mediastinal lymphadenectomy is deemed indispensable in lung cancer surgery for accurate staging and complete…
- Trial name
- NCT03216551
- Testing
- Intra-operative frozen section
- Where
- China
- Volunteers
- 1,076 people
- Sponsor
- Fudan University
Opaque Bottles, Conventional, Clear Bottles
Opaque Bottle Study
The proposed research aimed to conduct an intervention study assessing the effect of feeding mode (clear versus opaque bottle) on the quality and outcome of infant feeding interactions.
- Trial name
- NCT03711370
- Testing
- Clear Bottle, Opaque Bottle
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Lung Diseases
Diagnostic Value of Chest Ultrasound in Pediatrics Lung Diseases
To evaluate the accuracy of chest ultrasound for diagnosis of different lung lesions in comparison to the gold standard among children.
- Trial name
- NCT04326972
- Testing
- ultrasound
- Volunteers
- 50 people
- Sponsor
- Assiut University
Corneal Diseases
Dynamic Light Scattering and Keratoscopy for Corneal Examination
This pilot study will examine the usefulness of a new instrument called the Dynamic Light Scattering (DLS) device for documenting and monitoring changes in the cornea, the front part of the eye where contact lenses are placed.
- Trial name
- NCT00050466
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Cataract, Lens Opacities
A Comparison of FineVision Intraocular Lenses vs Symfony Intraocular Lenses
This is a prospective randomised open-label study with the aim to compare the visual performance of the trifocal FineVision® IOL versus the extended range of vision Symfony® IOL after phaco-emulsification cataract surgery.
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- NCT03974451
- Testing
- IOL implantation experimental, IOL implantation active comparator
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Children, Adult, Molar Incisor Hypomineralization
Effectiveness of Infiltration With Resin in Treatment of MIH Incisors in Children Showing Opacities
Enamel development defects are the result of a set of environmental, systemic and genetic causal agents that reveal a multifactorial etiology model, which in anterior teeth produces a serious aesthetic problem, converted into a…
- Conditions
- Children, Adult, Molar Incisor Hypomineralization, Dental Diseases, Opacity
- Trial name
- NCT05597956
- Testing
- white defects, yellow defects, brown defects
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- University of Valencia
Childhood Cataract
Infrared Choroidal Reflectance Camera for the Detection of Childhood Cataract
Sensitivity and specificity of current screening methods for childhood cataracts is poor. This results in delayed diagnosis and management which can decrease the visual prognosis following cataract surgery.
- Trial name
- NCT03035292
- Testing
- Red-reflex assessment, Infrared-reflex assessment
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust