Clinical trials: Open Fracture
Condylar Process of Mandible Open Fracture
Assessment of Condylar Position With Management of Unilateral Mandibular Angle Fracture
The objective of this study is to assess condylar position and occlusion after open reduction and internal fixation using two miniplates versus patient specific plate
- Trial name
- NCT07858890
- Testing
- 2 mini plates, patient specific plates
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Fractures, Bone, Nonunion of Fracture
Safety, Efficacy, & Use of ViviGen Cellular Bone Matrix Allograft in Orthopaedic Fracture Care
Prospective registry and retrospective data collection study to assess the efficacy and safety of Vivigen Cellular Bone Matrix (Vivigen) in orthopaedic trauma patients who require bone grafting in the acute, delayed, non-union…
- Conditions
- Fractures, Bone, Nonunion of Fracture, Fractures, Open, Fractures, Ununited
- Trial name
- NCT04299022
- Testing
- Vivigen Cellular Bone Matrix
- Where
- 4 sites in United States
- Volunteers
- 250 people
- Sponsor
- LifeNet Health
Surgery Complications, Surgery
SurgWeek-2: Identifying the Global Burden of Post Operative Complications: an International Prospective Cohort Study Protocol
This study aims to assess and improve the global outcomes following surgery. Every year approximately 313 million operations are performed, with 50 million people experiencing a complication and unfortunately 3.5 million people…
- Conditions
- Surgery Complications, Surgery, Global Surgery, Robotic
- Trial name
- SurgWeek-2 (NCT07785076)
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Fractures, Open
The Treatment of Type I Open Fractures in Pediatrics
Open fractures are frequently encountered in orthopaedics. Treatment usually calls for a formal, operative procedure in which the bone is exposed, foreign tissue is debrided and the wound is irrigated.
- Trial name
- PROOF (NCT00870064)
- Testing
- Formal Operative Treatment, Emergency Department Treatment
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Fracture, Bone Fracture
AI Assisted Detection of Fractures on X-Rays (FRACT-AI)
This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838).
- Conditions
- Fracture, Bone Fracture, Dislocation, Fracture Multiple
- Trial name
- FRACT-AI (NCT06130397)
- Testing
- Cases reading, Ground truthing
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Fractures, Open, Infections
Antibiotic Prophylaxis in Pediatric Open Fractures
This research will involve a prospective study on infection rates after grade 1 or 2 open fractures in the skeletally immature pediatric population.
- Trial name
- NCT06055712
- Testing
- Cefazolin, Cephalexin
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- St. Louis University
Open Fracture
Evaluation of STIMULAN Device and AI Model in Preventing Fracture Infections
This is a prospective, single-center, double-blind randomized clinical trial aimed at evaluating the efficacy and safety of the extended-release antibiotic device, STIMULAN, in preventing infections in patients with open…
- Trial name
- NCT06033534
- Testing
- STIMULAN
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Università Vita-Salute San Raffaele
Open tíbia Fracture
Management of Open Fracture Tibia in Teenagers
The aim of this study is to study the incidence of open tibial fractures in early teenagers and evaluate the management outcomes
- Trial name
- NCT06288139
- Volunteers
- 100 people
- Sponsor
- Assiut University
Open tíbia Fracture With Sub-segmental Bone Loss
Calcium Sulfate Spacer in Open Tibia Fractures
Investigators will compare antibiotic impregnated Calcium sulfate versus PMMA versus nothing in these sub-segmental bone defects.
- Trial name
- NCT03042546
- Testing
- Calcium Sulfate, PMMA, No treatment
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Washington
Orbital Floor (Blow-Out) Open Fracture, Enophthalmos Traumatic
3D Printed Titanium Mesh vs Guided Autogenous Graft
In this study, the hypothesis states that there is no significant difference between specified populations. In our case, the 3D printed patient-specific titanium mesh is thought to have the same effect and results in comparison…
- Trial name
- NCT05550285
- Testing
- orbital floor recontriction
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Mohammed Ghassan Mohammed Shaalan
Open Type III (A&B)Pediatric and Adolescent Tibial Shaft Fractures, Ilizarov Fixation
Illizarov Fixation in Open Type III (A&B) Pediatric and Adolescent Tibial Shaft Fractures
The Ilizarov method is our usual treatment of choice for open, complex, physeal or unstable fractures and for patients in whom non-operative or other treatments have failed .
- Trial name
- NCT05448053
- Testing
- Ilizarov
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Wound; Head, Multiple, Wound; Head, Scalp
Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Infection
- Trial name
- FTFDT3 (NCT03872544)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Wounds and Injuries, Wound Infection
Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries
- Trial name
- FTFDT2 (NCT03880188)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Type II and IIa Open Tibia Fractures
A Study of Immediate and Delayed Closure of Type II and IIIa Open Tibia Fractures
Delayed wound closure is considered by many to be the standard of care for the treatment of an open fracture. This study was conducted to determine the feasibility of a large multi-center prospective randomized clinical trial and…
- Trial name
- NCT01315392
- Testing
- delayed closure, immediate wound closure
- Where
- United States
- Volunteers
- 451 people
- Sponsor
- Wake Forest University Health Sciences
Tibia Fracture
Ilizarov Frame or Uni Planar External Fixator in the Cost-conscious Era
Tibial shaft fracture is a common injury worldwide. Their treatment, prognosis, and outcome are determined by the mechanism of injury, presence of communition, soft tissue injury and displacement.
- Trial name
- NCT03936972
- Testing
- ilizarov circular frame and uni-planarexternal fixator
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Tibial Fractures, Fractures, Open
Percutaneous Autologous Bone-marrow Grafting for Open Tibial Shaft Fracture
The treatment of open tibial shaft fracture is often complicated by delayed union or non-union. The objective of this study is to evaluate the efficacy of autologous concentrated bone-marrow to accelerate healing of open tibial…
- Trial name
- IMOCA (NCT00512434)
- Testing
- Osteosynthesis
- Where
- 11 sites in France
- Volunteers
- 85 people
- Sponsor
- University Hospital, Tours
Open Fracture Wounds
Fluid Lavage of Open Wounds
Open fracture wounds are a constant challenge to orthopaedic surgeons, with infections a common complication. There is currently little evidence as to which is the most effective way to wash out these wounds.
- Trial name
- FLOW (NCT00788398)
- Testing
- Saline Solution, Soap solution, Gravity Flow Irrigation
- Where
- 31 sites in United States, Australia and 3 more
- Volunteers
- 2,540 people
- Sponsor
- Prisma Health-Upstate
Tibial Fracture
Pin Site Infection Prevention for Open Tibial Fracture
This study aimed to compare the efficacy of pin-tract infection prevention between silversulfadiazine and dry dressing. Methods: 30 patients with an open tibial fracture admitted to Songklanagarind hospital from September 2007 to…
- Trial name
- NCT01017094
- Testing
- silversulfadiazine
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Prince of Songkla University