Clinical trials: Open Surgery
Incisional Hernia
Mini- or Less-Open Sublay Operation (MILOS) of Incisional Hernias
Prospective non-randomized observational register study of all elective symptomatic incisional hernias operated on in the Hernia Center of Reference of Gross Sand Hospital using the novel endoscopic assisted Mini- or Less-Open…
- Trial name
- NCT03133000
- Volunteers
- 615 people
- Sponsor
- Gross Sand Hospital
Resectable Simultaneous Colorectal Cancer Liver Metastasis
The Outcomes of Laparoscopic Hybrid Surgery Versus Totally Open Surgery
Simultaneous colorectal cancer liver metastasis (SCRLM) is one of the risk factors for poor prognosis in colorectal cancer. Surgical resection of primary and metastatic lesions is the first choice of treatment for patients with…
- Trial name
- NCT06550700
- Testing
- laparoscopic hybrid surgery (LHS)
- Where
- China
- Volunteers
- 266 people
- Sponsor
- Changhai Hospital
Carpal Tunnel Syndrome, Carpal Tunnel Release
Carpal Tunnel Release Through Mini Transverse Approach
Carpal tunnel release through dorsal wrist crease Mini Transverse incision, about 1.5 cm length.
- Conditions
- Carpal Tunnel Syndrome, Carpal Tunnel Release, Carpal Tunnel Surgery, Carpal Tunnel Transverse Approach
- Trial name
- CTRMTA (NCT02766114)
- Testing
- Carpal tunnel release through Mini Transverse Approach
- Where
- Syria
- Volunteers
- 43 people
- Sponsor
- Issa, Abdulhamid Sayed, M.D.
Open Abdomen Technique
NaROA STUDY: National Register of Open Abdomen
National Register of Open Abdomen Open Abdomen Procedure (Observational and Prospective Study)
- Trial name
- NaROA (NCT05343416)
- Testing
- Open abdomen procedure
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Hospital del Mar
Adult Patients Managed in a Cardiac Critical Care Unit With a Pathology Requiring at Least One Potentially Painful and Anxiety-provoking Invasive Procedure
Reorganization Strategy to Optimize the Use of Virtual Reality
The benefits of virtual reality (VR) in managing pain and anxiety for critical care patients has never been demonstrated, even if a positive effect has been demonstrated in other populations of patients.
- Trial name
- S'OUVRIR (NCT07132710)
- Testing
- Semi-structured interviews
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Hemophilia A
Nuwiq Dosing and Outcomes In the ManagEment of Women/Girls With Haemophilia A Needing FVIII Treatment for Surgery
Recombinant factor VIII for the prevention of bleeding in women/girls with haemophilia A undergoing major surgery
- Trial name
- NCT05936580
- Testing
- Nuwiq
- Where
- 16 sites in United States, Finland and 8 more
- Volunteers
- 28 people
- Sponsor
- Octapharma
Heart Defects, Congenital
Mixed Venous Oxygen Saturation From Central Venous Line, Venous Side of Heart Lung Machine and the Pulmonary Artery
This study was designed to examine if venous saturations from the central venous line and from the venous side of the heart lung machine are interchangeable or not with mixed venous saturation from the pulmonary artery in…
- Trial name
- NCT02498626
- Testing
- venous saturations
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Preoperative Anxiety Score
Virtual Reality to Reduce Anxiety During Thoracic Epidural Placement.
The purpose of this study is to investigate whether using a Virtual Reality (VR) headset can help young people relax during the placement of an epidural catheter for pain control after pectus surgery.
- Trial name
- NCT07911436
- Testing
- VR- headset
- Volunteers
- 78 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Congenital Heart Diseases
Ulinastatin Injection in in Pediatric Patients Undergoing Open Heart Surgery
1. Explore the efficacy of Ulinastatin use in improving post-operative pulmonary insufficiency and safety in pediatric patients undergoing scheduled CPB open heart surgery to treat Complex Congenital Heart Disease 2.
- Trial name
- NCT02527811
- Testing
- Ulinastatin
- Where
- 5 sites in China
- Volunteers
- 450 people
- Sponsor
- Techpool Bio-Pharma Co., Ltd.
Carcinoma, Non-Small-Cell Lung, Neoadjuvant Immunotherapy
Comparison of the Effect of Surgical Resection Based on Lesion Extent Before and After Neoadjuvant Therapy in Patients With Stage II-IIIB Non-Small Cell Lung Cancer: A Single-Center, Real-World, Open-Label Study
This study intends to conduct a prospective, non-interventional study to compare the survival benefits of different surgical resection patterns for patients with non-small cell lung cancer who have achieved partial response (PR)…
- Conditions
- Carcinoma, Non-Small-Cell Lung, Neoadjuvant Immunotherapy, Surgery
- Trial name
- NCT07373899
- Where
- China
- Volunteers
- 354 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Fractures, Open
The Treatment of Type I Open Fractures in Pediatrics
Open fractures are frequently encountered in orthopaedics. Treatment usually calls for a formal, operative procedure in which the bone is exposed, foreign tissue is debrided and the wound is irrigated.
- Trial name
- PROOF (NCT00870064)
- Testing
- Formal Operative Treatment, Emergency Department Treatment
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Cardiac Surgery, Cardiopulmonary Bypass
Voluven® in Paediatric Patients
This study will compare the clinical efficacy and safety of Voluven® and Human Albumin during elective open-heart surgery in pediatric patients.
- Trial name
- NCT00860405
- Testing
- HES 130/0.4 (6%) in sodium chloride (Voluven®, solution for infusion), Human serum albumin (HSA 50g/L), Human serum albumin (HSA 50g/L)
- Where
- 2 sites in Austria, Belgium
- Volunteers
- 61 people
- Sponsor
- Fresenius Kabi
Anesthesia
Trans-incisional Quadratus Lumborum Block Versus Caudal Analgesia in Pediatric Open Renal Surgeries.
There is scare literature about the usage of QLB in pediatric population, particularly the trans-incisional approach. Hence, the purpose of this study is to compare the postoperative analgesic efficacy of ultrasound-guided caudal…
- Trial name
- NCT04790318
- Testing
- Trans-incisional Quadratus lumborum block, Caudal block
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Liver Cirrhosis, Biliary
Autologous Bone Marrow Mononuclear Stem Cell for Children Suffering From Liver Cirrhosis Due to Biliary Atresia
The aim of this study was to evaluate the safety and effectiveness of autologous bone marrow mononuclear stem cell transplantation for Children Suffering from Liver Cirrhosis Due to Biliary Atresia
- Trial name
- NCT03468699
- Testing
- Autologous BMMC transplantation
- Where
- 2 sites in Vietnam
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Vinmec Research Institute of Stem Cell and Gene Technology
Primary Hyperparathyroidism
Open Versus Video-Assisted Minimal-Invasive Parathyroid Surgery
The aim of the present study was to compare open minimal-invasive parathyroid surgery with video-assisted parathyroidectomy in primary hyperparathyroidism (PHPT) patients with a positive sestamibi scan in a multicentre randomized…
- Trial name
- NCT00877981
- Testing
- Minimal invasive Parathyroid surgery
- Where
- 3 sites in Denmark, Sweden
- Volunteers
- 143 people
- Sponsor
- Uppsala University
Surgery, Colorectal Neoplasm
Predictive Factors of Conversion in Laparoscopic Colorectal Cancer Resection
Background Laparoscopic resection is the treatment of choice for colorectal cancer. Rates of conversion to open surgery range between 7% and 30% and controversy exists as to the effect of this on oncologic outcomes.
- Conditions
- Surgery, Colorectal Neoplasm, Laparoscopy
- Trial name
- NCT04589975
- Testing
- laparoscopic surgery
- Volunteers
- 829 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Minor, Scoliosis; Juvenile
Evaluation of a Prehabilitation Program in Patients Requiring Scoliosis Surgery.
Scoliosis is a curvature of the spine that, in the most severe cases, may require surgical treatment. This surgery is invasive and complex, causing anxiety for children, adolescents, and their parents.
- Conditions
- Minor, Scoliosis; Juvenile, Scoliosis; Adolescence, Surgery
- Trial name
- PHYPSYSCOL (NCT07852286)
- Testing
- Pre-habilitation program
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
Cardiac Surgery
Psychosocial Development of Children Undergoing Open Cardiac Surgery
In recent years, improvement of medical treatments leads to the effect, that 90% of children originally born with congenital heart disease (CHD) are reaching adulthood.
- Trial name
- NCT03646565
- Where
- Hungary
- Volunteers
- 80 people
- Sponsor
- Semmelweis University Heart and Vascular Center
Gastroesophageal Reflux
Is Laparoscopic Fundoplication Better Than Open Fundoplication in Children ?
The aim of the study was to compare short- and longterm outcomes after laparoscopic and open Nissen fundoplication in children.
- Trial name
- NCT01551134
- Testing
- Fundoplication
- Where
- Norway
- Volunteers
- 88 people
- Sponsor
- Oslo University Hospital
Ewing's Sarcoma
Study of Intensive Chemotherapy, Surgery and Radiotherapy to Treat Ewing's Sarcoma in Children and Young Adults
Tumors of the Ewing sarcoma family (ES) affect children, adolescents and young adults. The reported incidence is 0.6 cases per million inhabitants every year.
- Trial name
- NCT01696669
- Testing
- Chemotherapy, Surgery, Radiotherapy
- Where
- 9 sites in Spain
- Volunteers
- 43 people
- Sponsor
- Grupo Espanol de Investigacion en Sarcomas