Clinical trials: Ophthalmic Surgery
Surgical Procedure, Unspecified, Ocular Discomfort
Lateral Rectus Muscle Tendon Elongation
To evaluate a technique using resected medial rectus muscle transplantation for elongation of Lateral rectus tendon as a monocular surgery for large angle sensory exotropia.
- Conditions
- Surgical Procedure, Unspecified, Ocular Discomfort, Strabismus, Divergent
- Trial name
- NCT04286945
- Testing
- LATERAL RECTUS MUSCLE AUGMENTED RECESSION BY ELONGATION OF THE TENDON WITH AUTOGRAFT FROM RESECTED MEDIAL RECTUS MUSCLE
- Volunteers
- 16 people
- Sponsor
- Tanta University
Cataract, Miosis
Nepafenac Versus Ketorolac Eye Drops in Prevention of Intraoperative Miosis During Cataract Surgery
This study aim at determining the efficacy of Nepafenac and Ketorolac in obtaining adequate intraoperative mydriasis and preventing miosis during cataract surgery.
- Trial name
- NCT03851172
- Testing
- Ketorolac Ophthalmic, Nepafenac Ophthalmic, Cyclopentolate Ophthalmic
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Assiut University
Epiretinal Membrane
Phacoemulsification and 25 Gauge (25G) Vitrectomy Versus Phacoemulsification Only in Idiopathic Epiretinal Membranes
The purpose of the study is to evaluate the difference in Early Treatment Diabetic Retinopathy Study (ETDRS) visual acuity, oct retinal thickness and microperimetry in 2 groups of 30 eyes each affected by idiopathic epiretinal…
- Trial name
- NCT01771939
- Testing
- 25-G vitrectomy and phacoemulsification, phacoemulsification (cataract surgery)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Turin, Italy
Strabismus
Symmetrical Versus Asymmetrical Surgery for Asymmetrical Inferior Oblique Overaction
Overaction of the inferior oblique (IO) muscle is a commonly observed component of childhood strabismus, and is often seen combined with other ocular deviations.
- Trial name
- NCT03507712
- Testing
- Symmetrical IO weakening, Asymmetrical IO weakening
- Where
- Oman
- Volunteers
- 28 people
- Sponsor
- Sultan Qaboos University
Trauma, Macular Hole
Comparative Study Between Early Vitrectomy and Observation for Spontaneous Closure of Traumatic Macular Hole
The purpose of this study is to compare the anatomical and visual recovery of eyes with traumatic macular hole (TMH) following either early vitrectomy or 6-month observation.
- Trial name
- NCT01509092
- Testing
- vitrectomy surgery
- Where
- 8 sites in China
- Volunteers
- 44 people
- Sponsor
- Peking University Third Hospital
Anesthesia, Strabismus
Post-Operative Nausea and Vomiting in Children Submitted to Strabismus Surgery
Background: Postoperative nausea and vomiting (PONV) is one of the main causes of patient and family dissatisfaction, which may delay the onset of oral intake and postpone discharge.
- Conditions
- Anesthesia, Strabismus, PONV
- Trial name
- NCT04060771
- Testing
- Palonosetron, Dexamethasone
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Universidade Federal Fluminense
Optic Nerve Sheath Diameter, Caudal Block
Effect of Caudal Block Injection Rate on Optic Nerve Sheath Diameter in Pediatric Surgeries
Our prospective observational study will include patients between the ages of 1-7 years, ASA 1-2, who will undergo elective surgery under general anesthesia, whose consent was obtained by their parents for the procedure to be…
- Trial name
- NCT06187714
- Testing
- caudal block rate
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Cataract
Hypnosis for Eye Surgery
Perioperative stress for cataract surgery in the elderly is considerable even in the absence of pain. For these patients with a high comorbidity level, the perioperative situation comprising factors such as uncomfortable…
- Trial name
- NCT00176098
- Testing
- Hypnoanalgesia; Hypnotic shielding
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Heidelberg University
Cataract
Effect of the Timing of Cataract Surgery on Complications in Patients With Bilateral Congenital Cataracts
Congenital cataract is an important treatable cause of visual handicap in childhood throughout the world. Successful management of childhood cataract is dependent on individualized treatment strategies and rigorous postoperative…
- Trial name
- NCT02581046
- Testing
- Phacomulsification lens removal cataract surgery without Intraocular lens(IOL) implantation at the age of 3month of the patients, Phacomulsification lens removal cataract surgery without Intraocular lens(IOL) implantation at the age of 6 month of the patients, Subconjunctival dexamethasone and general anesthesia
- Where
- China
- Volunteers
- 61 people
- Sponsor
- Sun Yat-sen University
Surgery--Complications, Retinoblastoma Bilateral
Sutures in Orbital Implants in Retinoblastoma Patients
The purpose of this study is to evaluate different sutures for orbital implants in retinoblastoma patients.
- Trial name
- NCT04383860
- Testing
- 5-0 suture, 4-0 suture
- Volunteers
- 132 people
- Sponsor
- Sun Yat-sen University
Strabismus
Balance in the Strabismic Patient Undergoing Strabismus Surgery
Strabismus is a clinical condition characterized by the failure of the visual axes of the two eyes to align on the stared object.
- Trial name
- BASS (NCT06733220)
- Testing
- Surgery for strabismus
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Esotropia
Early Versus Delayed Surgery for Infantile Esotropia
The goal of this study is to determine whether corrective surgery done earlier than the current standard can better improve the visual and eye movement deficits in children with infantile esotropia (crossed eyes in infancy).
- Trial name
- NCT01166503
- Testing
- mVEP Testing, Stereoacuity Testing, Optokinetic nystagmus testing
- Where
- Canada
- Volunteers
- 71 people
- Sponsor
- The Hospital for Sick Children
Anxiety, Strabismus
Does Anxiety in Children on the Day of Surgery Impact Compliance in the Ophthalmology Clinic?
The hypothesis is that pediatric patients with increased levels of anxiety on the day of surgery, in particular at point of anesthetic induction, will demonstrate decreased compliance with assessment in ophthalmology clinic…
- Conditions
- Anxiety, Strabismus, Compliance
- Trial name
- NCT02704442
- Where
- Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Queen's University
Open Angle Glaucoma (OAG)
CyPass Clinical Experience Study
This study is to evaluate the long-term safety, effectiveness and clinical experience of the CyPass Micro-Stent in patients with glaucoma.
- Trial name
- CyCLE (NCT01097174)
- Testing
- CyPass Micro-Stent
- Where
- 14 sites in Austria, Bulgaria and 4 more
- Volunteers
- 555 people
- Sponsor
- Transcend Medical, Inc.
Inflammation and Pain Associated With Cataract Surgery
2nd Study to Assess ISV-305 Compared to Vehicle for Treatment of Inflammation and Pain Associated With Cataract Surgery
The purpose of this study is to evaluate the ocular safety, tolerability, and efficacy of ISV-305 (Dexamethasone in DuraSite® 2) compared to Vehicle in the treatment of inflammation and pain associated with cataract surgery.
- Trial name
- ISV-305 (NCT03192150)
- Testing
- ISV-305, Vehicle
- Where
- United States
- Volunteers
- 246 people
- Sponsor
- Sun Pharmaceutical Industries Limited
Cataract
Modified Surgical Techniques for Pediatric Cataract Treatment
Pediatric cataract is totally different from adult cataract. There is traditionally no difference in technique between pediatric and adult cataract surgery.
- Trial name
- NCT01844258
- Testing
- Modified technique, Traditional technique
- Where
- China
- Volunteers
- 37 people
- Sponsor
- Sun Yat-sen University
Glaucoma, Filtering Surgery
Long-Term IOP Fluctuation and VF Progression After Triple Procedure
Long-term intraocular pressure (IOP) fluctuation may be significantly associated with the progression of glaucomatous visual field loss, even in patients kept always low IOP after triple procedure, an effective approach for…
- Conditions
- Glaucoma, Filtering Surgery, Intraocular Pressure
- Trial name
- NCT00428740
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Yonsei University
Retinal Detachment
Correlation Between OCT and mFERG Findings With VA After Vitrectomy Surgery for Retinal Detachment
Correlation between optical coherence tomography and multifocal electroretinogram findings with visual acuity after vitrectomy surgery for Retinal detachment.
- Trial name
- NCT05993208
- Testing
- optical coherence tomography,multifocal electroretinogram. VA measurment
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- New Valley University
Cataract
Subfoveal Choroidal Thickness After Surgery for Age-related Cataracts
To compare the effects of femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification surgery (CPS) on subfoveal choroidal thickness (SFCT) in age-related cataracts.
- Trial name
- NCT02895074
- Testing
- Femtosecond laser-assisted cataract surgery, Conventional phacoemulsification cataract surgery, Tropicamide
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Sun Yat-sen University
Congenital Cataract
Aphakia Versus Pseudophakia in Children Under 2 Years Undergoing Bilateral Congenital Cataract Surgery
The purpose of this study is to document the safety and efficacy of primary IOL implantation in children below 2 years of age undergoing congenital cataract surgery.
- Trial name
- NCT01297153
- Testing
- Intraocular Lens (Acrysof IOL), No IOL
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Iladevi Cataract and IOL Research Center