Clinical trials: Oral Glucose Tolerance
Diabetes Mellitus, Type 1
Oral Insulin for Prevention of Diabetes in Relatives at Risk for Type 1 Diabetes Mellitus
Type 1 diabetes (T1D) is an autoimmune disease. This means that the immune system (the part of the body which helps fight infections) mistakenly attacks and destroys the cells that produce insulin (islet cells found in the…
- Trial name
- TN07 (NCT00419562)
- Testing
- Oral Insulin
- Where
- 18 sites in United States, Australia and 4 more
- Volunteers
- 560 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Cystic Fibrosis
Oral Glucose Tolerance Testing Using Candy for Cystic Fibrosis
The study aims to determine if a popular dextrose candy alternative yields a similar glycemic curve compared to the standard oral Dextrose solution used in the Oral Glucose Tolerance Test.
- Trial name
- NCT04579939
- Testing
- Candy Glucose Tolerance Test
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Oral Glucose Tolerance Test, Low Birth Weight
Association Between Low Plasma Glucose After Oral Glucose Tolerance Test in Pregnancy With Impaired Fetal Growth
Objective: To study the association of low maternal plasma glucose in 2 hour 75 g oral glucose tolerance test (OGTT) in women with impaired birth weight and determinate if this result is predictive of low birth weight (<10th…
- Trial name
- NCT04144595
- Testing
- 2 hour 75 g Oral glucose tolerance test
- Where
- Mexico
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Insulin Resistance
Effect of Vitamin D Supplementation on Oral Glucose Tolerance Among Obese Adolescents
Childhood obesity is a rapidly growing epidemic in the US and the world. Current estimates suggest that 30% of our nation's children are either overweight ot obese.
- Trial name
- NCT01856946
- Testing
- 4,000 IU vitamin D3
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Obesity
Longitudinal Assessment of Cardiovascular and Metabolic Parameters in Obese and Lean Children
The investigators hypothesize that cardiovascular and metabolic alterations due to obesity already manifest at childhood age. To identify these alterations and risk factors, the investigators have established a cohort of 177…
- Trial name
- NCT01605123
- Where
- 2 sites in Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Type 1 Diabetes
Home-based Oral Glucose Tolerance Test for Type 1 Diabetes Screening
This study aims at quantifying the accuracy of a self-administered fingerstick based glucose tolerance test (GTT@Home) respect to the gold-standard in-clinic venous plasma measures during the oral glucose tolerance test (OGTT)…
- Trial name
- NCT07155252
- Testing
- GTT@Home
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Yale University
Chronic Pancreatitis, Pancreatogenic Type 3C Diabetes Mellitus
Evaluation of OGTT in Patients With Post-pancreatitis Diabetes Mellitus for Diagnosis and Characterization
To evaluate the islet function and insulin secretion pattern of post-pancreatitis diabetes mellitus by oral glucose tolerance testing, and to explore the pathophysiological characteristics of PPDM-C which provide evidence for the…
- Conditions
- Chronic Pancreatitis, Pancreatogenic Type 3C Diabetes Mellitus, Diabetes Mellitus, Oral Glucose Tolerance Test
- Trial name
- NCT05989867
- Testing
- blood test, Continuous Glucose Monitor
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Changhai Hospital
Diabetes, Impaired Glucose Tolerance (IGT)
A Survey on the Rate of Glucose Intolerance in Hong Kong Chinese
Hypothesis: There is a high rate of glucose intolerance among Hong Kong Chinese. The investigators plan to screen Hong Kong Chinese from the community with oral glucose tolerance test (OGTT).
- Conditions
- Diabetes, Impaired Glucose Tolerance (IGT), Impaired Fasting Glucose (IFG), Glucose Intolerance
- Trial name
- NCT00787215
- Testing
- observational: no treatment involved
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Diabetes Mellitus, Type 1
GPPAD-POInT (Global Platform of Autoimmune Diabetes - Primary Oral Insulin Trial)
The GPPAD-POInT Study is designed as a randomized, placebo-controlled, double blind, multicentre, multinational primary prevention phase IIb study aiming to induce immune tolerance to beta-cell autoantigens through regular…
- Trial name
- NCT03364868
- Testing
- Oral Insulin
- Where
- 7 sites in Belgium, Germany and 3 more
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Childhood Obesity
Leipzig Childhood Obesity Study
The aim of this study is to identify polymorphisms that make children and adolescents more prone to obesity and metabolic dysfunction, as well as to identify biomarkers that are linked to causes and consequences of obesity.
- Trial name
- NCT04491344
- Where
- Germany
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Cystic Fibrosis, Cystic Fibrosis-related Diabetes
Alternate Measures of Glucose During OGTT Testing for CFRD
Although early detection and treatment of cystic fibrosis-related diabetes (CFRD) can lead to significant clinical improvements and prolong life, rates of screening are poor likely due to the burdensome nature of oral glucose…
- Trial name
- NCT05568134
- Testing
- Oral glucose tolerance test
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Children's Hospital of Philadelphia
Cystic Fibrosis
Comparing Laboratory Blood Glucose Results With HemoCue Glucose 201 RT
There are very few studies comparing the accuracy, sensitivity and specificity of HemoCue glucose 201 RT system with the laboratory gold standard.
- Trial name
- CFRD (NCT01883037)
- Testing
- Blood glucose results
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Type 1 Diabetes (T1D), Autoantibodies
Standardized Italian netwoRk Enrolling iNdividuals With Islet-Autoantibodies
This project characterizes the longitudinal progression of children and adults who have tested positive for one or more islet cell autoantibodies across the early stages of type 1 diabetes (T1D).
- Conditions
- Type 1 Diabetes (T1D), Autoantibodies, Hyperglycemia, Impaired Glucose Tolerance (Prediabetes)
- Trial name
- SIRENA (NCT07503366)
- Where
- 24 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Società Italiana di Endocrinologia e Diabetologia Pediatrica
Cystic Fibrosis Related Diabetes, Cystic Fibrosis
The Use of Home Oral Glucose Tolerance Test Kit in Screening Cystic Fibrosis Related Diabetes
The aim of this study is to establish if the self-administered electronic Oral Glucose Tolerance Test kit can increase the annual uptake of screening for CFRD in children who are between 10 and 17 years of age with CF.
- Trial name
- HomeOGTT (NCT02703155)
- Testing
- Home Oral Glucose Tolerance Test kit
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Blood Glucose, High, Oral Hypoglycaemic Overdose
Impact of Oral Glucose Tolerance Test on Extent of Hemoglobin Glycation
The glycation extent of human hemoglobin is under control of the Maillard reaction, a chemical interaction between an amino acide and a reducing sugar.
- Trial name
- HbA1c (NCT04018430)
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Urs E. Nydegger
Impaired Glucose Tolerance
Voglibose Tablets 0.2 / OD Tablets 0.2 Special Drug Use Surveillance "Long-term Use in Patients With Impaired Glucose Tolerance"
The purpose of this study is to determine the safety and efficacy of long-term use of Voglibose (Basen) to prevent progression to type 2 diabetes mellitus in participants with impaired glucose tolerance in the routine clinical…
- Trial name
- NCT01993927
- Testing
- Voglibose
- Where
- Japan
- Volunteers
- 742 people
- Sponsor
- Takeda
Type 1 Diabetes
The Insulin Independence Trial (IIT) Evaluating the Safety and Efficacy of Oral Cyclosporine and Oral Omeprazole for Insulin Independence Among Recent Onset Type 1 Diabetes Patients
The purpose of this study is to determine if the combination of oral cyclosporine, an immune therapy and oral omeprazole, a proton pump inhibitor, are effective in rendering insulin independence among recent onset type 1 diabetes…
- Trial name
- IIT (NCT01762644)
- Testing
- Oral Cyclosporine and Oral Omeprazole, Oral Omeprazole
- Sponsor
- Perle Bioscience, Inc.
Screening of Cystic Fibrosis Related Diabetes
Comparing Two Different Approaches in the Screening of Cystic Fibrosis Related Diabetes
The incidence of cystic fibrosis related diabetes (CFRD) has risen significantly as patients' survival improves. Early diagnosis of CFRD is crucial to prevent the unnecessary deterioration of lung function and nutritional status…
- Trial name
- CFRD (NCT01091025)
- Testing
- Glucose profile for 2 weeks
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Imperial College London
Iron Overload, Hemoglobinopathies
Comparing CGM and OGTT in Relation to Iron Overload Detected by Pancreas T2* MRI in High-Risk Hematology Group
A prospective, observational, comparative study with no intervention.The objective of the study to compare the efficiency of detecting glycemic abnormalities using Continuous Glucose Monitoring (CGMs) versus Oral Glucose…
- Conditions
- Iron Overload, Hemoglobinopathies, Lymphoma, Acute Lymphoblastic Leukemia
- Trial name
- CGMs (NCT03141398)
- Testing
- Continuous Glucose Monitoring (CGM), Oral Glucose Tolerance Test (OGTT), T2* MRI of the Pancreas
- Sponsor
- Hamad Medical Corporation
Gestational Diabetes
Prevention of Gestational Diabetes
Gestational diabetes mellitus (GDM)is a major health problem growing prevalence of obesity the older age of pregnant women A randomized controlled trial in 54 pregnant voluntary women at high risk for GDM.
- Trial name
- NCT01130012
- Testing
- Lifestyle: diet and exercise, Close follow-up: reporting diaries of food and exercise
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital