Clinical trials: Oral Submucous Fibrosis
Oral SubMucous Fibrosis
Evaluation of Efficacy of Aloevera in the Treatment of Oral Submucous Fibrosis- A Clinical Study
Oral submucous fibrosis is a chronic, insidious disease caused by arecanut use and is associated with both significant morbidity (including burning sensation and reduced oral opening) and an increased risk of malignancy.
- Trial name
- NCT02714543
- Testing
- aloevera juice, Hydrocortisone, Hyaluronic Acid
- Volunteers
- 74 people
- Sponsor
- The Oxford Dental College, Hospital and Research Center, Bangalore, India
Triamcinolone, Pentoxifylline
Comparison of Triamcinolone With Pentoxifylline and Vitamin- E Efficacy in the Treatment of Stage 2 and 3 Oral Submucous Fibrosis
To compare the efficacy of Triamcinolone with Pentoxifylline and Vitamin E in patients with stage two and three oral submucous fibrosis.
- Conditions
- Triamcinolone, Pentoxifylline, Vitamin E, Oral Submucosa Fibrosis
- Trial name
- NCT05660694
- Testing
- Triamcinolone, Pentoxifylline with Vitamin E
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Oral Submucous Fibrosis
Efficacy of Curcumin in Oral Submucous Fibrosis
The purpose of the study is to determine whether the formulations of curcumin will effect the clinical signs and symptoms and histopathological features in patients with clinical stage 2 oral submucous fibrosis (OSMF).
- Trial name
- ECOSMF (NCT03511261)
- Testing
- 10% Curcumin mucoadhesive gel, Curcumin capsules 500mg, 5% curcumin mucoadhesive gel + Curcumin capsules 250 mg
- Where
- India
- Volunteers
- 200 people
- Sponsor
- H.K.E.S's S.Nijalingappa Institute of Dental Science and Research
The Study Focuses on the Saliva as Potential Source of Early Detection of Oral Cancer
EVALUATION OF SALIVA AS LIQUID BIOPSY FOR EARLY DETECTION OF ORAL CANCER IN PATIENTS WITH ORAL-SUBMUCOUS FIBROSIS (OSMF)
Oral cancer is the top cancer in Pakistan, accounting for 27%, and it has a high mortality rate due to late-stage diagnosis. It primarily affects the lips, tongue, cheeks, and floor of the mouth.
- Trial name
- Sal (NCT07122128)
- Testing
- saliva a a diagnostic tool for early detection of oral cancer
- Where
- Pakistan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Liaquat University of Medical & Health Sciences