Clinical trials: Orthodontic Appliances, Fixed
White Spot Lesion
The Effect of ICON Treatment on WPL With Patients After Fixed Orthodontic Appliances
The aim of this study is to determine the effect of ICON on White spot lesions compared to CPP-ACPF plus.
- Trial name
- NCT03391180
- Testing
- ICON Remineralization, CPP-ACPF
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Inflammation, Oxidative Stress
Oxidative-reductive Processes and the Degree of Inflammation in Saliva With Conventional Brackets and Clear Aligners
The purpose of this prospective observational study is to evaluate the differences in oxidative-reductive processes and the degree of inflammation in saliva during treatment with conventional brackets and clear aligners.
- Conditions
- Inflammation, Oxidative Stress, TNF-α
- Trial name
- NCT06507592
- Testing
- Saliva samples collection
- Where
- Italy
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Relapse
CAD/CAM Fixed Retainers vs. Conventional Multistranded Fixed Retainers in Orthodontic Patients. Comparison of Stability, Retainer Failure Rate, Adverse Effects, Cost-effectiveness, and Patient Satisfaction. A Randomized Controlled Clinical Trial
Introduction: Orthodontic retainers are used after the completion of orthodontic treatment to assure dental occlusal stability and to maintain the achieved end-result.
- Trial name
- Retention (NCT04389879)
- Testing
- Bonding of either CAD/CAM or conventional multistranded stainless steel fixed retainer
- Where
- 2 sites in Denmark, Norway
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
White Spot Lesion of Tooth, Long Term Adverse Effects
Comparison of Efficacy Of Probiotic Toothpaste and Chlorhexidine Mouthwash To Reduce S.Mutans
Orthodontic appliance causes increase in plaque accumulation, especially around brackets, wires and attachments. Advances in orthodontics in recent time have led to improved quality of appliance and treatment procedures…
- Conditions
- White Spot Lesion of Tooth, Long Term Adverse Effects, Caries, Dental, Orthodontic Appliance Complication
- Trial name
- NCT03004196
- Testing
- Probiotic Toothpaste, Dr. Reddy's Clohex, Control Group
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peoples University, Bhanpur, Bhopal
Orthodontic Appliance Complication, Orthodontic Appliance Design
Periodontal and Orthodontic Outcomes of Straight vs. Looped Fixed Retainers
The goal of this split-mouth, head-to-head, randomized controlled trial is to compare the effects of a fixed straight retainer with the V- loop bonded retainer on periodontal health in patients with the requirement of continuous…
- Conditions
- Orthodontic Appliance Complication, Orthodontic Appliance Design, Orthodontic Treatment
- Trial name
- NCT05644119
- Testing
- V- loop Bonded Orthodontic Retainer, Straight Wire Retainer
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Dental Plaque Accumulation
Effectiveness of Ortho-Buddy on Plaque Control in Orthodontic Patients
The goal of this clinical trial is to learn whether the Ortho-Buddy toothbrush can improve plaque removal in adolescents undergoing orthodontic treatment with fixed appliances.
- Trial name
- NCT07810868
- Testing
- Standard Toothbrush, Ortho-Buddy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Rutgers, The State University of New Jersey
Orthodontic Tooth Movement
GCF Volume Changes in Aligners and Fixed Appliances
Orthodontic tooth movement induces biological responses in periodontal tissues that can be reflected by changes in gingival crevicular fluid (GCF).
- Trial name
- GCF-OTM (NCT07480538)
- Testing
- Clear Aligner Therapy, Fixed Appliance
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Deep Bite, Skeletal Class I Malocclusion
Effects of Anterior Bite Raisers Combined With Fixed Orthodontic Appliances in Deep Bite Treatment
This clinical study evaluated the treatment outcomes of fixed orthodontic appliances combined with anterior bite raisers in patients with skeletal Class I malocclusion and deep bite.
- Conditions
- Deep Bite, Skeletal Class I Malocclusion, Anterior Bite
- Trial name
- NCT07907263
- Testing
- Fixed Orthodontic Appliance With Composite Anterior Bite Raiser
- Where
- Vietnam
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Periodontal Diseases
Periodontal Health Knowledge Among Patients With Fixed Orthodontic Appliance
The study is a cross-sectional survey investigating the Periodontal health knowledge among patients with fixed orthodontic appliance attending the orthodontic department and the paid section faculty of dentistry Cairo University.
- Trial name
- NCT04532255
- Where
- Egypt
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Cairo University
Class II Malocclusion, Class II Malocclusion, Division 1
Comparison of Early Interceptive Orthodontic Appliances (Traditional and Novel) and Later Fixed Appliance Treatment in Class II Malocclusion.
Background Approximately 15% of children have a Class II malocclusion, where the maxilla is positioned anterior to the mandible, and around 90% of these children also present with an increased overjet.
- Conditions
- Class II Malocclusion, Class II Malocclusion, Division 1, Overjet
- Trial name
- MACTWin (NCT07404696)
- Testing
- Head gear activator, Twin Block, Invisalign mandibular advancement
- Where
- 3 sites in Sweden
- Volunteers
- 144 people
- Sponsor
- Vastra Gotaland Region
Halitosis, Probiotics
The Effect of Oral Probiotics on Oral Hygiene and Halitosis in Orthodontic Patients.
Brackets, bands, ligatures and wires in patients receiving orthodontic treatment with fixed appliances are areas that trap food and impede oral hygiene.
- Conditions
- Halitosis, Probiotics, Orthodontic Appliance Complication
- Trial name
- NCT05651503
- Testing
- Probiotics
- Where
- Greece
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Athens
Pain
Methods That Reduce Pain During Debonding Fixed Orthodontic Appliance
The goal of this clinical trial is to evaluate the effectiveness of four different methods (including the control group) in reducing pain during debonding of fixed orthodontic appliances in participants requiring the removal of…
- Trial name
- NCT05904587
- Testing
- SureSmile® VPro™, ortho technology, sports advantage, thermal forming soft EVA 3mm, cotton roll
- Where
- Iraq
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Dental Crowding, Vibrational Force
Intermittent Vibrational Force and Orthodontic Tooth Movement
The aim of this study is to compare the clinical efficiency of conventional fixed appliance orthodontic treatment with that supplemented by the daily application of cyclic forces to the dentition via a removable (AcceleDent)…
- Conditions
- Dental Crowding, Vibrational Force, Fixed Orthodontic Appliances
- Trial name
- NCT02314975
- Testing
- AcceleDent vibrational device, Fixed appliance only
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- King's College London
Plaque-Induced Gingivitis, Dental Plaque Accumulation
Innovative Mouthwash in School-Aged Children With Fixed Orthodontic Appliances
Fixed metal orthodontic appliances create additional plaque-retentive areas around brackets, archwires and ligatures, making mechanical plaque control more difficult in children and adolescents.
- Conditions
- Plaque-Induced Gingivitis, Dental Plaque Accumulation, Halitosis
- Trial name
- NCT07710144
- Testing
- Test mouthwash, Chlorhexidine-containing mouthwash
- Where
- Bulgaria
- Volunteers
- 90 people
- Sponsor
- Plovdiv Medical University
Traumatic Oral Ulceration, Orthodontic Treatment
Comparison of Hyaluronic Acid and Chlorhexidine Gels for Traumatic Oral Ulcers During Fixed Orthodontic Treatment
This randomized controlled trial aims to compare the effectiveness of topical hyaluronic acid gel and chlorhexidine gel in the management of traumatic oral ulcers that develop following placement of fixed orthodontic appliances.
- Conditions
- Traumatic Oral Ulceration, Orthodontic Treatment, Orthodontic Appliances, Fixed, Oral Mucosal Ulceration
- Trial name
- HYCHO-TOU (NCT07709455)
- Testing
- Hyaluronic Acid gel, Chlorhexidine gel
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Dow University of Health Sciences
Patient Compliance
The Influence of Weekly Reminders on Enhancing Patient Compliance in Patients With Fixed Orthodontic Treatment
this study is a randomized clinical trial to evaluate the effect of sending weekly reminders to patients undergoing fixed orthodontic appliance treatment.
- Trial name
- NCT05331820
- Testing
- weekly mobile reminder
- Where
- Iraq
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Shara Qadir Hussein
White Spot Lesion of Tooth
White Spot Lesions Prevention During Orthodontic Fixed Appliance Treatment: a Randomized Clinical Trial
The aim of this study is to evaluate the effectiveness of calcium fluoride nanoparticles containing orthodontic primer in preventing or decreasing the incidence WSLs over a period of 6 months in patients with fixed orthodontic…
- Trial name
- NCT04994314
- Testing
- nCaF2 primer, Control primer
- Where
- Iraq
- Volunteers
- 31 people
- Sponsor
- University of Baghdad
Root Resorption
Root Resorption Accompanied Clear Aligners and Fixed Orthodontic Appliance
The aim of the study is to compare apical root resorption accompanied orthodontic treatment using clear aligners vs fixed appliances.
- Trial name
- NCT05232318
- Testing
- Leveling and alignment
- Where
- 2 sites in Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Oral Hygiene
Effect of Dental Waterjet on Oral Hygiene for Patients With Braces
The aim of this study is to assess the efficacy of dental water jet in plaque removal and gingival health during orthodontic treatment with fixed appliances.
- Trial name
- NCT03119441
- Testing
- Dental Water Jet, Dental Floss
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Angle Class 2 Malocclusion
Clear Aligners vs Fixed Appliances for Molar Distalization Using Infrazygomatic Crest Screws
This study compares three different methods of moving upper back teeth backward (distalization) to create space for crowded or protruding teeth, all supported by small temporary screws placed in the cheekbone area (infrazygomatic…
- Trial name
- NCT07714603
- Testing
- Pitts21® fixed appliance, Invisalign® Clear Aligners, ClearCorrect Clear Aligners
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- TC Erciyes University