Clinical trials: Orthodontic Movement
Healthy, Maxillary First Premolar Tooth Extraction
Gingival Crevicular Fluid Characterization During Orthodontic Treatment
During Orthodontic tooth movement, teeth are moved through alveolar bone under applied forces. The applied mechanical loading force must be transferred to the alveolar bone via periodontal ligament (PDL).
- Conditions
- Healthy, Maxillary First Premolar Tooth Extraction, Canine Retraction
- Trial name
- NCT04226469
- Testing
- Tooth movement
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Effect of Platelet Rich Fibrin With Different Tooth Movements
Evaluation of Different Orthodontic Tooth Movements Assisted With Injectable Platelet Rich Fibrin
The present prospective clinical study will be undertaken for assessment of the effect of application of i-PRF on the rate of levelling and alignment, molar distalization\& intrusion of anterior teeth in deep bite cases
- Trial name
- NCT05616936
- Testing
- injectable platelet rich fibrin
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Crowding, Vibrational Force
Intermittent Vibrational Force and Orthodontic Tooth Movement
The aim of this study is to compare the clinical efficiency of conventional fixed appliance orthodontic treatment with that supplemented by the daily application of cyclic forces to the dentition via a removable (AcceleDent)…
- Conditions
- Dental Crowding, Vibrational Force, Fixed Orthodontic Appliances
- Trial name
- NCT02314975
- Testing
- AcceleDent vibrational device, Fixed appliance only
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- King's College London
Rate of Canine Retraction
The Effectiveness of Double-slot Brackets Versus Single-slot Brackets on the Rate of Canine Retraction
The aim of this Randomized clinical trial is to compare the efficacy of the double slot brackets compared to single slot-brackets in producing a controlled rate of upper canine retraction into premolar extraction space.
- Trial name
- NCT06481761
- Testing
- Double-slot brackets, Single-slot brackets
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain Perception, Root Resorption
The Potential Effect of the Local Administration of Vitamins C and E on Orthodontic Treatment: A Randomized Clinical Trial
Brief Summary of the Study This study investigates the effects of locally administered vitamins C and E on orthodontic tooth movement during the initial stage of treatment.
- Conditions
- Pain Perception, Root Resorption, Rate of Orthodontic Tooth Movement, Biomarkers
- Trial name
- NCT06847880
- Testing
- 1: Vitamin C Supplementation, Vitamin E Supplementation, Saline Solution (Control)
- Where
- 3 sites in Iraq
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Dental Malocclusion, Maxillary Deficiency
Effect on Periodontal Phenotype of Flapless Piezoincission During Orthodontic Treatment
Research Question While the reduction in treatment times and the patient satisfaction after periodontally accelerated osteogenic orthodontics (PAOO) are well sustained in the scientific literature, there is still controversy…
- Trial name
- Piezo_Ortho (NCT06315348)
- Testing
- flapless alveolar decortication with augmentation
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Complutense de Madrid
Malocclusion, Angle Class II
Effects of Power Arm Application in Maxillary Canine Distalization
The aim of this study is to investigate the effects of a canine distalization force applied between power arms placed on the maxillary canine and first molar, in comparison with the classical method without power arms.
- Conditions
- Malocclusion, Angle Class II, Tooth Movement Techniques, Orthodontic Anchorage Procedures
- Trial name
- NCT07866976
- Testing
- Canine and molar power arms, Conventional canine retraction
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Atlas University
Dental Malocclusion
Laser in Orthodontic Leveling and Alignment
to evaluate the outcome of LLLT regarding leveling and alignment of the mandibular anterior segment.
- Trial name
- NCT04376164
- Testing
- low level laser therapy
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Tharwat osman Mohi Eldeen Elshehawy
Class II Malocclusion
Clinical Effects of Electrical Stimulation on Speeding up Orthodontic Tooth Movement
Thirty two patients requiring extraction of maxillary first premolars and en-masse retraction of upper anterior teeth will participate in the study.
- Trial name
- NCT05302076
- Testing
- Low-intensity electrical current (LIEC), Traditional fixed orthodontic appliance
- Where
- Syria
- Volunteers
- 32 people
- Sponsor
- Damascus University
Collagen Degeneration
Type I Collagen Fragments in the GCF and Saliva During OTM
Investigate the levels of type I Collagen fragments ICTP and CTX in GCF and saliva during initial leveling and alignment of the teeth in a sample of adolescents undergoing orthodontic treatment.
- Trial name
- NCT05020431
- Testing
- Biological measuring of collagen fragments biomarker during orthodontic tooth movement
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Low Level Laser Therapy, Canine Retraction
Three-dimensional Assessment of the Bone Changes Accompanying Laser-assisted Orthodontic Tooth Movement
Aim of the present study is to evaluate the effect of low-level laser therapy on bone quality and quantity with orthodontic tooth movement.
- Conditions
- Low Level Laser Therapy, Canine Retraction, Orthodontic Tooth Movement
- Trial name
- NCT05811728
- Testing
- Low level laser therapy, without beam emission
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Nourhan M.Aly
Orthodontic Tooth Movement
The Effect of Number of Micro-osteo-perforations on the Rate of Tooth Movement.
The objective of this split mouth trial is to compare mean canine retraction with one Micro-osteo-perforation (MOP) against three MOPs among Class II division I orthodontic patients after one month of intervention.
- Trial name
- MOPs (NCT05995509)
- Testing
- Micro-osteo-perforations
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rehman Medical Institute - RMI
Dental Malocclusions, Angle Class II, Division 1
Flapless Mops for Acceleration of Canine Retraction
The aim of the present clinical study was directed to evaluate the effectiveness of micro-osteoperforations on the rate of canine retraction; in addition, the potential risk for root resorption during maxillary canine retraction.
- Conditions
- Dental Malocclusions, Angle Class II, Division 1, Bimaxillary Protrusion
- Trial name
- NCT04383600
- Testing
- Micro-osteoperforation
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Ahmed Akram Elawady
Orthodontic Tooth Movement, Intrusion of Tooth
Evaluation of Root Resorption Following Different Mandibular Incisors Intrusive Mechanics
Evaluation of root resorption following different mandibular incisors intrusive mechanics : A randomized clinical trial
- Conditions
- Orthodontic Tooth Movement, Intrusion of Tooth, Resorption, Root
- Trial name
- NCT05414019
- Testing
- Mini-screw, Utility arch, Nitinol reverse curve wire
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Mesial Movement of Teeth
Full Thickness Mucoperiosteal Flap Versus Low Level Laser in Orthodontic Tooth Movement Acceleration
This study aimed to evaluate the effect of using full thickness mucoperiosteal flap (FTMPF) elevation only versus low level laser therapy (LLLT) on acceleration of orthodontic tooth movement.
- Trial name
- NCT04055935
- Testing
- elevation of full thickness mucoperiosteal flap, low level laser therapy
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Malocclusion
The Effect of OrthoPulse Photobiomodulation on the Rate of Tooth Movement During Alignment With Fixed Appliances
The aim of this study is to determine efficacy of OrthoPulse photobiomodulation on the rate of tooth movement during alignment for Subjects receiving fixed appliance orthodontic treatment.
- Trial name
- NCT03202355
- Testing
- Fixed Appliance Orthodontic Treatment, OrthoPulse™
- Where
- 3 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Biolux Research Holdings, Inc.
Teeth Mesial Drift, Bone Injury
Biological Anchorage With Selective Micro-osteoperforations (MOPs) in Canine Distalization
To evaluate the effect of selective micro-osteoperforations (MOPs) on the amount of distal movement of the upper canine, the mesio-distal inclination of the canine and the messiah movement of the upper first molar.
- Conditions
- Teeth Mesial Drift, Bone Injury, Orthodontic Pathological Resorption of External Root
- Trial name
- NCT03741504
- Testing
- micro-osteoperforations (MOPs)
- Where
- 2 sites in Colombia
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Fundación Universitaria CIEO
Orthodontic Treatment, Tooth Crowding
Assessment of the Efficacy of the Aerodentis System
The purpose of this study is to evaluate the efficacy of the Aerodentis System for orthodontic tooth movement in an open label, two-arms, non-inferiority clinical study.
- Conditions
- Orthodontic Treatment, Tooth Crowding, Orthodontics
- Trial name
- NCT03421886
- Testing
- Aerodentis system, Invisalign clear aligner system
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Pain Management, Root Resorption
Photobiomodulation Effect on Vietnamese Orthodontic Patients
Since most orthodontic cases endure for 2 to 3 years or longer, patients are at a high risk of inflammatory root resorption and prolonged orthodontic pain, which is a common and unwanted side effect of their treatment.
- Conditions
- Pain Management, Root Resorption, Orthodontic, Tooth Movement
- Trial name
- NCT07276984
- Testing
- LED device
- Where
- Vietnam
- Volunteers
- 16 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Clear Aligner Appliance
Evaluation of the Efficacy of Injectable Platelet-rich Plasma in Tooth Movement Acceleration With Clear Aligner
Aim of the study is evaluation of the efficacy of injectable platelet-rich plasma in orthodontic tooth movement acceleration with clear aligner
- Trial name
- NCT07103551
- Testing
- Platelet-rich plasma
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University