Clinical trials: Orthopaedic Injury
Coronavirus Infection, Orthopedic Disorder
Retrospective Case Series of COVID19+ Patients Undergoing Orthopedic Surgery
Over the last months, the Rizzoli Orthopedic Institute in Bologna, Italy, has drained orthopedic urgencies from all other hospitals in the urban and suburban area.
- Conditions
- Coronavirus Infection, Orthopedic Disorder, Bone Fracture, Bone Metastases
- Trial name
- COVID19&SURG (NCT05881343)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Istituto Ortopedico Rizzoli
Osteoarthritis (OA), Longevity
Registry of Outcomes of Dezawa MuseCells®
The goal of this observational study is to learn about the long-term effects of Dezawa MuseCells to treat various diseases. The Primary Goal: What is the short-term and long- term outcomes of Dezawa Musecells? Participants…
- Conditions
- Osteoarthritis (OA), Longevity, Wound Care, Pain
- Trial name
- NCT07645989
- Testing
- MuseCell Treatment
- Where
- 2 sites in United States, Mexico
- Volunteers
- 5,000 people
- Sponsor
- MuseCell Innovations Pte LTD
Osteosarcoma, Pediatric
Oncological and Functional Outcomes in Lower Limb Osteosarcoma Pediatric Patient
Retrospective analysis of specific characteristics of complications and long-term oncological and function outcomes in lower-limb osteosarcoma pediatric patients.
- Conditions
- Osteosarcoma, Pediatric, Lower Limb Injury, Outcome
- Trial name
- NCT06162962
- Testing
- Retrospective analysis
- Where
- China
- Volunteers
- 345 people
- Sponsor
- Changye Zou
Neck of Femur Fracture, Fractures, Bone
A Quality Improvement Project to Assess and Refine the Handover Process at Morning Trauma Meetings
This project was intended to observe the handover of trauma and orthopaedic patients at a district general hospital in the UK. Following the implementation of a standard operating protocol, the handover of patient information…
- Conditions
- Neck of Femur Fracture, Fractures, Bone, Orthopedic Disorder
- Trial name
- NCT04514601
- Testing
- Standard Operating Protocol
- Where
- United Kingdom
- Volunteers
- 317 people
- Sponsor
- Sandwell & West Birmingham Hospitals NHS Trust
Anterior Cruciate Ligament Injury, Knee Injury
Comparison of Quadriceps and Semitendinosus Grafts in ACL Reconstruction Using Data From the Danish Knee Ligament Reconstruction Registry (DKRR)
This study looks at two different types of tendon (tissue) used in knee surgery to repair a torn anterior cruciate ligament (ACL), which is a common injury in active people.
- Conditions
- Anterior Cruciate Ligament Injury, Knee Injury, Ligament Reconstruction, Sports Injuries
- Trial name
- NCT06980285
- Where
- Denmark
- Volunteers
- 2,500 people
- Sponsor
- Abdirahman Hassan Omar
Forearm Injuries, Radius Fractures
Time to Healing in Displaced Pediatric Diaphyseal Forearm Fractures Treated With Bioabsorbable Compared to Titanium Intramedullary Nails
This study looks at children with forearm fractures that need surgery. The standard treatment uses titanium nails, which usually need to be removed in a second operation later.
- Conditions
- Forearm Injuries, Radius Fractures, Ulna Fractures, Fractures, Bone
- Trial name
- FOREST (NCT07536581)
- Testing
- Bioabsorbable intramedullary nail, Titanium elastic intramedullary nail
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Children's Fractures Interest Group, Denmark
Simulation Based Medical Education
Optimizing Simulation-Based Training in Orthopedics: Exploring Deliberate Flawed Performance for Dynamic Hip Screw Osteosynthesis
Proximal femoral fractures (PFF) are associated with increased mortality when surgical intervention is delayed, with evidence supporting osteosynthesis within 12 to 24 hours of admission to minimize risk.1, 2 Consequently…
- Trial name
- NCT06729372
- Testing
- Deliberate Flawed Performance, Error Avoidance Training
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Proximal Femoral Fracture
Proximal Femur Image Database Validation
The AO@AI Turin project is a collaborative project with a Turin group and the AO (Arbeitsgemeinschaft für Osteosynthesefragen, or in English, Association for the Study of Internal Fixation) foundation.
- Trial name
- NCT06351943
- Testing
- Fracture classification annotations provided by the Turin group, Fracture classification annotations provided by the AO expert surgeon group
- Where
- Switzerland
- Volunteers
- 2,932 people
- Sponsor
- AO Innovation Translation Center
Covid19, Trauma
Impact of COVID-19 Pandemic on Orthopaedic Practice
The COVERT Collaborative is led by a group of academic surgeons that is looking into the impact of the unprecedented COVID-19 pandemic on Trauma and Orthopaedic practice.
- Conditions
- Covid19, Trauma, Orthopedic Disorder, Anesthesia
- Trial name
- COVERT (NCT05026788)
- Testing
- type of treatment
- Where
- United Kingdom
- Volunteers
- 5,000 people
- Sponsor
- Imperial College Healthcare NHS Trust
Bone Fractures, Radius Fractures
Management of Distal Radius Fractures in Children Younger Than 11 Years Old.
This fractures have been managed with anatomical reduction performed under anesthesia or using sedatives. In our institution this means prolonged hospital stay, involvement of an anesthesiologist and the use of an special room in…
- Conditions
- Bone Fractures, Radius Fractures, Closed Fractures
- Trial name
- NCT02670629
- Testing
- Partial reduction with overriding position, Closed anatomic reduction
- Volunteers
- 58 people
- Sponsor
- Carlos A Acosta-Olivo
Long Bone Fractures
Registry of Pediatric Orthopedic Trauma and Health Outcomes in Skeletally Immature Children
International registry to collect prospective treatment and outcomes data on specific, key non-pathological fractures in children with open physes.
- Trial name
- NCT04207892
- Testing
- Conservative (non-surgical) treatment, Surgical treatment
- Where
- 17 sites in United States, Australia and 10 more
- Volunteers
- 1,000 people
- Sponsor
- AO Innovation Translation Center
Sports Medicine Injuries
Effect of Personalized Pain Coaches After Orthopaedic Surgery for Patients With Sports Medicine Injuries
Patients experiencing sports medicine-related injuries are particularly vulnerable to developing both chronic pain and experiencing prolonged opioid use.
- Trial name
- NCT05821699
- Testing
- LCS (Life Care Specialist), Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 148 people
- Sponsor
- Emory University
Tendon Disorder
A Musculoskeletal Ultrasound Course for Orthopedic Surgery Residents
A group of orthopedic surgery residents underwent a structured online and practical musculoskeletal ultrasound course. Their proficiency on a written and practical exam, as well as frequency and comfort when using was recorded…
- Trial name
- NCT04204369
- Testing
- Ultrasound education curriculum
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Trauma Centers, Trauma Patients
Assess the Efficacy of Tailored Patient Information and Voluntary Patient-managed Outpatient Digital Follow-up (I-POD) as an Adjunct to Standard Treatment According to National Guidelines in the National Trauma Plan Among Adult Trauma Patients in Norway.
The POSTRAUMA trial is a clinical trial at The Regional trauma centre of Western Norway, Haukeland University Hospital. Trauma is the leading cause of death worldwide in patients aged 1-45 years.
- Conditions
- Trauma Centers, Trauma Patients, Trauma (Including Fractures), Trauma Injury
- Trial name
- POSTRAUMA (NCT07268716)
- Testing
- The intervention is a tailored patient Information and Patient-managed Outpatient Digital follow-up treatment
- Where
- Norway
- Volunteers
- 256 people
- Sponsor
- Haukeland University Hospital
Developmental Dysplasia of Hip, DDH
8 vs 12 Weeks: A Pavlik Harness Trial
Developmental dysplasia of the hip is the most common bone and joint condition in babies. It is usually treated with a harness that holds the hips in a safe position so they can develop normally.
- Conditions
- Developmental Dysplasia of Hip, DDH, Developmental Dysplasia of the Hip, Developmental Dysplasia of the Hip (DDH)
- Trial name
- NCT07847619
- Testing
- Pavlik Harness
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- The Hospital for Sick Children
Surgical Site Infection, Vancomycin
Pharmacokinetics of Preoperative Vancomycin
A study of plasma and tissue vancomycin pharmacokinetics in pediatric surgical patients.
- Trial name
- NCT03453684
- Testing
- Administration of Vancomycin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Pediatric Distal Forearm Fractures
Closed Reduction of Distal Forearm Fractures by Pediatric Emergency Medicine Physicians: A Prospective Study
Distal forearm fractures are amongst the most frequently encountered orthopedic injuries in the pediatric emergency department (ED). Immediate closed manipulation and cast immobilization, is still the mainstay of management.
- Trial name
- NCT01101607
- Testing
- Distal Forearm Fracture Reduction
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- InMotion Orthopaedic Research Center
Bone Fractures
AI-Assisted Fracture Detection in Emergency Radiography
This study evaluates whether artificial intelligence (AI) can support doctors who interpret X-rays for suspected fractures in emergency care.
- Trial name
- FAIR (NCT06754137)
- Testing
- BoneView AI-Assisted Radiograph Interpretation
- Where
- 3 sites in Austria, Germany
- Volunteers
- 1,667 people
- Sponsor
- Salzburger Landeskliniken
Thigh Muscle Injury, Thigh Injury
PPP Versus Corticosteroid for Thigh Muscle Injuries
The purpose of this study is to compare the number of days it takes for a sport participant to return to play between ultrasound guided intramuscular corticosteroid injections and platelet-poor plasma (PPP) injections for thigh…
- Conditions
- Thigh Muscle Injury, Thigh Injury, Musculoskeletal, Musculoskeletal Injury Trauma
- Trial name
- NCT07513142
- Testing
- Corticosteroid, Platelet Poor Plasma
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Andrews Research & Education Foundation
Bone Fractures
Splinting Versus Casting for Type I Supracondylar Fractures
Elbow fractures are very common in young children. Type I supracondylar fractures are stable fractures to the elbow that are treated conservatively across the world and typically heal very well without complications.
- Trial name
- NCT01912365
- Testing
- Above Elbow Cast, Long Arm Splint
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University of British Columbia