Clinical trials: Orthopaedic Trauma
LET, ACL Reconstruction
Long-term Follow up of the Stability 1 Trial
From 2014-2017, across 7 Canadian and 2 European sites, we randomized 618 patients at high-risk of re-injury, to anterior cruciate ligament reconstruction (ACLR) with or without a lateral extraarticular tenodesis (LET) and…
- Conditions
- LET, ACL Reconstruction, Osteoarthritis (OA) of the Knee
- Trial name
- STABILITY LTF (NCT06885372)
- Testing
- Lateral Extra-Articular Tenodesis (LET), ACL Reconstruction
- Where
- 8 sites in Canada, United Kingdom
- Volunteers
- 510 people
- Sponsor
- Western University, Canada
Trauma, Congenital Bone and Joint Abnormalities
Telemedicine Consultation in Trauma and Orthopedic
The purpose of this study is to determine whether telemedicine consultations (lead by standard scheme)allows to increase quality of anatomical and functional outcomes and improve clinical work-flow at patients with acute bone and…
- Conditions
- Trauma, Congenital Bone and Joint Abnormalities, Joint Diseases, Orthopedic Surgery Complications
- Trial name
- TeleTO (NCT00815243)
- Testing
- Telemedicine consultation, Treatment plan
- Where
- 5 sites in Ukraine
- Volunteers
- 300 people
- Sponsor
- Donetsk National Medical University
Forearm Injuries, Radius Fractures
Time to Healing in Displaced Pediatric Diaphyseal Forearm Fractures Treated With Bioabsorbable Compared to Titanium Intramedullary Nails
This study looks at children with forearm fractures that need surgery. The standard treatment uses titanium nails, which usually need to be removed in a second operation later.
- Conditions
- Forearm Injuries, Radius Fractures, Ulna Fractures, Fractures, Bone
- Trial name
- FOREST (NCT07536581)
- Testing
- Bioabsorbable intramedullary nail, Titanium elastic intramedullary nail
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Children's Fractures Interest Group, Denmark
Fracture; Complication Orthopedic Procedure
The Effect of Using a Kaleidoscope on Fear and Pain in Children
The research was conducted in randomized controlled experimental type between May 2022 and December2023. The universe of the research consisted of children and their parents who were diagnosed with a fracture, applied to the…
- Trial name
- NCT06261112
- Testing
- kaleidescope
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mihriban Culha
Bone Fractures
AI-Assisted Fracture Detection in Emergency Radiography
This study evaluates whether artificial intelligence (AI) can support doctors who interpret X-rays for suspected fractures in emergency care.
- Trial name
- FAIR (NCT06754137)
- Testing
- BoneView AI-Assisted Radiograph Interpretation
- Where
- 3 sites in Austria, Germany
- Volunteers
- 1,667 people
- Sponsor
- Salzburger Landeskliniken
Fractures, Bone, Nonunion of Fracture
Safety, Efficacy, & Use of ViviGen Cellular Bone Matrix Allograft in Orthopaedic Fracture Care
Prospective registry and retrospective data collection study to assess the efficacy and safety of Vivigen Cellular Bone Matrix (Vivigen) in orthopaedic trauma patients who require bone grafting in the acute, delayed, non-union…
- Conditions
- Fractures, Bone, Nonunion of Fracture, Fractures, Open, Fractures, Ununited
- Trial name
- NCT04299022
- Testing
- Vivigen Cellular Bone Matrix
- Where
- 4 sites in United States
- Volunteers
- 250 people
- Sponsor
- LifeNet Health
Fracture, Trauma
Surgical Treatment Versus Non-surgical Treatment of Ulnar Fractures
The purpose of this study is to determine if surgery using a plate and screws to fix a forearm fracture (ulnar shaft) will improve functional outcome compared to non-operative treatment out to 1 year of follow-up.
- Conditions
- Fracture, Trauma, Ulna Fracture, Orthopedic
- Trial name
- NCT01123447
- Testing
- Open reduction and internal fixation, Closed reduction and short-arm cast
- Where
- 9 sites in Canada, United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Calgary
Anterior Cruciate Ligament Injury, Knee Injury
Comparison of Quadriceps and Semitendinosus Grafts in ACL Reconstruction Using Data From the Danish Knee Ligament Reconstruction Registry (DKRR)
This study looks at two different types of tendon (tissue) used in knee surgery to repair a torn anterior cruciate ligament (ACL), which is a common injury in active people.
- Conditions
- Anterior Cruciate Ligament Injury, Knee Injury, Ligament Reconstruction, Sports Injuries
- Trial name
- NCT06980285
- Where
- Denmark
- Volunteers
- 2,500 people
- Sponsor
- Abdirahman Hassan Omar
Orthopedic Disorder, Fractures, Bone
Efficacy of Virtual Reality in Pain Reduction in Orthopedic Pediatric Patients
To prospectively determine if pediatric patients undergoing orthopedic procedures can benefit from employing virtual reality for pain management.
- Trial name
- NCT04901793
- Testing
- Virtual Reality Headset and handheld remote control.
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Ochsner Health System
Lower Limb Injury
IV Steroids Versus Steroids Included in Block for Orthopedic Lower Limb Surgery
IV and included steroids have produced the same length of block prolongation in adults as if the steroid was given with the nerve block. Clinically, this has not be noticed in children.
- Trial name
- NCT03855059
- Testing
- Dexamethasone Sodium Phosphate
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Arizona
Long Bone Fractures
Registry of Pediatric Orthopedic Trauma and Health Outcomes in Skeletally Immature Children
International registry to collect prospective treatment and outcomes data on specific, key non-pathological fractures in children with open physes.
- Trial name
- NCT04207892
- Testing
- Conservative (non-surgical) treatment, Surgical treatment
- Where
- 17 sites in United States, Australia and 10 more
- Volunteers
- 1,000 people
- Sponsor
- AO Innovation Translation Center
Orthopedic Disorder, Orthopedic Devices Associated With Misadventures
Coracoid Tunnel Widening After ACJ Tight Rope Fixation
studying coracoid tunnel widening after arthroscopic fixation of acute acromioclavicular joint (ACJ) dislocation using TightRope system and its correlation with loss of reduction and the functional scores.
- Trial name
- NCT05504538
- Testing
- arthroscopic fixation of Acute acromioclavicular joint injury using tight rope, Tight rope
- Volunteers
- 23 people
- Sponsor
- Cairo University
Chimerism, Blood Transfusion
Transfusion-Associated Microchimerism in Previously Injured Individuals Who Received a Blood Transfusion
Blood transfusions are frequently necessary in situations in which there is a large amount of blood loss. In some individuals who receive a blood transfusion, white blood cells from the donor's blood may remain in the body for…
- Conditions
- Chimerism, Blood Transfusion, Wounds and Injuries
- Trial name
- NCT00441779
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Fracture Forearm, Pediatric ALL
Taking POSNA's OrthoKids to the People
The objective of this project is to determine the efficacy of a tablet-based educational intervention at improving orthopaedic health literacy amongst families of pediatric patients treated for fractures in an outpatient setting.
- Trial name
- NCT04996745
- Testing
- Tablet-based educational intervention
- Where
- United States
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Trauma/Injury Problem
Virtual Reality Pain Control Orthopedic Trauma
The treatment of postoperative pain after severe trauma is poorly understood, and it can lead to chronic pain, opiate drug addiction and elevated health care costs.
- Trial name
- VROT (NCT02100163)
- Testing
- Virtual Reality Hypnosis, Audio Hypnosis, Standard treatment
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- National Institute of General Medical Sciences (NIGMS)
Pediatric Distal Forearm Fractures
Closed Reduction of Distal Forearm Fractures by Pediatric Emergency Medicine Physicians: A Prospective Study
Distal forearm fractures are amongst the most frequently encountered orthopedic injuries in the pediatric emergency department (ED). Immediate closed manipulation and cast immobilization, is still the mainstay of management.
- Trial name
- NCT01101607
- Testing
- Distal Forearm Fracture Reduction
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- InMotion Orthopaedic Research Center
Pediatric, Fracture
Investigation Of Bioabsorbable Screws In Pediatric Orthopedic Surgery
This study is a prospective randomized controlled trial comparing the clinical outcomes of bioabsorbable screws to conventional metal screws in pediatric patients (aged 0 to 18) undergoing surgical fixation for trauma or elective…
- Conditions
- Pediatric, Fracture, Orthopedic Devices Associated With Misadventures, Surgical Instruments, Materials and Devices (Including Sutures), Patient Satisfaction
- Trial name
- NCT06429267
- Testing
- Bioabsorbable Screw, Metal/Titanium Screw
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Sports Injury, Orthopedic Disorder
Training of Falling Techniques on Landing Mechanics
The overall purpose of this study is to quantify the effect and retention of one-week training of falling techniques on landing biomechanics associated with anterior cruciate ligament (ACL) loading compared to soft-landing…
- Conditions
- Sports Injury, Orthopedic Disorder, Knee Injuries, Anterior Cruciate Ligament Injuries
- Trial name
- NCT04768088
- Testing
- Falling Training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Wyoming
Surgical Site Infection, Vancomycin
Pharmacokinetics of Preoperative Vancomycin
A study of plasma and tissue vancomycin pharmacokinetics in pediatric surgical patients.
- Trial name
- NCT03453684
- Testing
- Administration of Vancomycin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Trauma Centers, Trauma Patients
Assess the Efficacy of Tailored Patient Information and Voluntary Patient-managed Outpatient Digital Follow-up (I-POD) as an Adjunct to Standard Treatment According to National Guidelines in the National Trauma Plan Among Adult Trauma Patients in Norway.
The POSTRAUMA trial is a clinical trial at The Regional trauma centre of Western Norway, Haukeland University Hospital. Trauma is the leading cause of death worldwide in patients aged 1-45 years.
- Conditions
- Trauma Centers, Trauma Patients, Trauma (Including Fractures), Trauma Injury
- Trial name
- POSTRAUMA (NCT07268716)
- Testing
- The intervention is a tailored patient Information and Patient-managed Outpatient Digital follow-up treatment
- Where
- Norway
- Volunteers
- 256 people
- Sponsor
- Haukeland University Hospital