Clinical trials: Osteocalcin
Obesity, Insulin Resistance
Vitamin K and Glucose Metabolism in Children at Risk for Diabetes (Vita-K 'n' Kids Study)
The undercarboxylated fractions of the two vitamin K-dependent proteins osteocalcin and matrix Gla protein have been shown to play key roles in type 2 diabetes and cardiovascular disease (at least in mouse models).
- Conditions
- Obesity, Insulin Resistance, Insulin Sensitivity, Prediabetes
- Trial name
- NCT01972113
- Testing
- Low-Dose Vitamin K2 (menaquinone-7; 45 mcg/d), High-Dose Vitamin K2 (menaquinone-7; 90 mcg/d)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Augusta University
Infant Vitamin K Status, Vitamin K Deficiency Bleeding
The OK Daily Study
The OK Daily Study is a multi-centred, part-randomised, part blinded, four cohort study. We are exploring daily dietary supplementation with vitamin K2, specifically menaquinone-7 (MK-7), given to breastfed infants or…
- Trial name
- NCT07620236
- Testing
- Combined MK-7 + vitamin D3 drops, Vitamin D3 Drops, MK-7 capsules
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Bone Mineral Density, Body Fat Distribution
The Bone-Fat-Pancreas Axis in Children
The overarching hypothesis of this proposal is that obesity and positive energy balance in children promote both low bone mass accrual and risk for diabetes through events that are mechanistically associated and that involve bone…
- Conditions
- Bone Mineral Density, Body Fat Distribution, Insulin Homeostasis
- Trial name
- NCT01041898
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Osteopenia, Osteoporosis
The Long-term Effect of Daily Jarlsberg Cheese Intake in Patient With Osteopenia
Aim: To estimate the effect of daily optimal efficacy dose (OED) of Jarlsberg cheese in patients with Osteopeni (OP). Study population: Post-menopausal women and men above 55 years of age in risk of Osteoporosis Treatment: Daily…
- Trial name
- PF-JB3 (NCT06358443)
- Testing
- Jarlsberg cheese
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Meddoc
Nutritional Rickets, Bone Turnover Rate Disorder
Effectiveness of Vitamin C Supplementation in Treatment of Rickets
Effectiveness of therapeutic dose of vitamin C in infants and children with nutritional rickets as an adjuvant therapy with vitamin D and calcium The study is two armed Randomized Control Trial, to validate the role of Vit C…
- Trial name
- NCT05310760
- Testing
- Vit C
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Cairo University
Hip Fracture
Nutritional Risk Factors for Hip Fracture: a Case Control Study
Low Body Mass Index (BMI) is a risk factor for hip fracture, but it is unknown if it is the low BMI per se that increases risk of hip fracture or if specific micro-nutrients contribute.
- Trial name
- NCT01738776
- Where
- Norway
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Healthy
The Effect of Vitamin K Supplementation on Osteocalcin Carboxylation in Healthy Children
Background of the study: Results from several studies show that vitamin K has an important function in bone metabolism. In a previous cross-sectional study conducted by our department, evidence for a poor vitamin K status of bone…
- Trial name
- NCT00402974
- Testing
- menaquinone 7
- Where
- Netherlands
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Tooth Movement
OC and ICTP in Gingival Crevicular Fluid During Piezocision Accelerated Orthodontic Treatment
The aim of this study was to evaluate the tooth movement with and without piezocision with regard to the levels of osteocalcin and cross-linked C-terminal telopeptides of type I collagen in the gingival crevicular fluid.
- Trial name
- NCT04611984
- Testing
- Piezocision, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Marmara University