Clinical trials: Ovarian Reserve
Uterine Fibroids (Leiomyoma), Myomectomy
Bilateral Uterine Artery Occlusion During Laparoscopic Myomectomy
The current study is a multiple-arm, single blinded, and controlled randomized trial. It will be conducted in two gynecological endoscopy centers: • ElShatby University Hospital, a tertiary level hospital in Alexandria, Egypt.
- Conditions
- Uterine Fibroids (Leiomyoma), Myomectomy, Myomectomy; Surgical Blood Loss
- Trial name
- NCT07352761
- Testing
- Temporary clipping of uterine artery, Temporary occlusive suturing of uterine artery, Bipolar coagulation of uterine arteries
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Ovarian Torsion
Effect of Simultaneous Cystectomy on Ovarian Reserve in Cases of Adnexal Detorsion
There are mostly ovarian cysts under adnexal torsion from gynecological emergencies. There are many studies in the literature examining the effect of adnexal detorsion on ovarian reserve.
- Trial name
- NCT05702099
- Testing
- ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people
- Sponsor
- Bagcilar Training and Research Hospital
Fertility Issues, Vaccine Adverse Reaction
COVID-19 Vaccine and Ovarian Reserve
As Israel is the first country to widely vaccinate its population using the mRNA vaccine against COVID-19, evaluating its influence on ovarian reserve is essential .
- Trial name
- NCT04748172
- Testing
- SARS-CoV-2 virus vaccines, AMH sampling, anti Covid-19 antibody levels (Serology)
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Abdominal Pain, Ovarian Spillage
Single-port LC Might be Preferable for Managing Ovarian Dermoid Cyst.
Minimally invasive surgery has become the standard treatment for many gynecologic disease processes. In the last decade, numerous studies have demonstrated that laparoscopic approaches to various gynecologic oncology…
- Conditions
- Abdominal Pain, Ovarian Spillage, Endobag Rupture, Ovarian Reserve
- Trial name
- NCT02009228
- Testing
- Ovarian cystectomy
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Anti-Mullerian Hormone Isoforms
Measurement of Different Anti-Müllerian Hormone Isoforms in Expected Poor Responders
This study wants to evaluate significant clinical impact of different AMH isoforms in serum can be present or absent in expected poor responder participants.
- Trial name
- NCT03826888
- Where
- United Arab Emirates
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Irregular Menses
Electroacupuncture for Diminished Ovarian Reserve
Diminished ovarian reserve (DOR)is a disease can not be cured. Medicine for DOR includes dehydroepiandrosterone (DHEA), hormone replacement therapy (HRT), immunosuppressive agents and alternative therapy, etc.
- Trial name
- NCT02229604
- Testing
- EA, HRT, DHEA and herb
- Volunteers
- 57 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Pregnancy, Ovarian
Biomarkers of Ovarian Reserve and Correlation With IVF Treatments
Retrospective study to evaluate the correlation between AFC, FSHb, AMH and IVF outcomes of 347 cycles performed with three different protocols.
- Trial name
- NCT02442895
- Where
- Italy
- Volunteers
- 236 people
- Sponsor
- U.O.S. Procreazione Medicalmente Assistita e Congelamento Gameti
GH, Low Ovarian Reserve
To Explore the Effect of GH Pretreatment on Clinical Outcomes in Patients With Low Ovarian Reserve
Growth hormone (GH) has been used in the field of assisted reproduction technology for over 30 years. Studies for GH have been exploring in the applicable population, drug dosage, starting time and time limitation.
- Trial name
- NCT04384783
- Testing
- growth hormone
- Volunteers
- 114 people
- Sponsor
- Guangzhou First People's Hospital
Anaplastic Large Cell Lymphoma, Burkitt Lymphoma
Blood Sample Markers of Reproductive Hormones in Assessing Ovarian Reserve in Younger Patients With Newly Diagnosed Lymphomas
This clinical trial studies blood sample markers of reproductive hormones in assessing ovarian reserve in younger patients with newly diagnosed lymphomas.
- Conditions
- Anaplastic Large Cell Lymphoma, Burkitt Lymphoma, Diffuse Large B-Cell Lymphoma, Hodgkin Lymphoma
- Trial name
- NCT01793233
- Testing
- Laboratory Biomarker Analysis, Questionnaire Administration
- Where
- 107 sites in United States, Canada
- Volunteers
- 203 people
- Sponsor
- Children's Oncology Group
Cancer
Evaluating a New Gonadotoxic Risk Stratification System
The primary objective of this study is to assess if there is an association between a newly described gonadotoxic risk stratification system and post-treatment ovarian reserve as determined by FSH and AMH.
- Trial name
- NCT05052632
- Sponsor
- University of Colorado, Denver
Premature Ovarian Insufficiency, Ovarian Reserve Function
Therapeutic Effect of Vitamin C Supplementation in Patients With Ovarian Aging
The goal of this clinical trial is to learn if Vitamin C works to improve ovarian reserve in women with ovarian aging. It will also learn about the safety of Vitamin C.
- Trial name
- NCT06794060
- Testing
- Vitamin C (Ascorbic Acid)
- Volunteers
- 354 people
- Sponsor
- Peking University Third Hospital
Ovarian Reserve
Ovarian Reserve Following Bilateral Salpingectomy Versus Tubal Ligation During Cesarean Section
The aforementioned study was designed to evaluate short term ovarian reserve as assessed by anti-Mullerian hormone(AMH) levels following bilateral salpingectomy versus tubal ligation, as part of cesarean sections performed in…
- Trial name
- NCT02377128
- Testing
- Bilateral salpingectomy, Tubal ligation
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Antimullerian Hormone, Ovarian Cysts
The Effect of Surgery for Non Endometriosic Ovarian Cysts on Ovarian Reserve
The main objective is to evaluate the ovarian reserve after laparoscopic cystectomy. The secondary objective is the analysis of predictors of change in the ovarian reserve after surgery
- Conditions
- Antimullerian Hormone, Ovarian Cysts, Antral Follicle Count
- Trial name
- NCT02852447
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Corporacion Parc Tauli
Infertility, Female, Miscarriage
Is Decreased Ovarian Reserve Related to an Increased Number of Previous Early Miscarriages?
This study aims to explore the potential correlation between decreased ovarian reserve and previous history of early miscarriage.
- Conditions
- Infertility, Female, Miscarriage, Miscarriage, Recurrent, IVF
- Trial name
- NCT05969574
- Testing
- Transvaginal ultrasound, Blood test AMH
- Where
- 3 sites in United Arab Emirates
- Volunteers
- 2,059 people
- Sponsor
- ART Fertility Clinics LLC
Low Ovarian Reserve, Poor Response to Ovulation Induction Poseidon Type IV
Follicular Flushing Using Double Lumen Needle Versus Direct Aspiration in Low Prognosis Patients According to the POSEIDON Criteria
This is a prospective, randomized, controlled clinical trial designed to evaluate whether follicular flushing increases the number of cumulus-oocyte complexes (COCs) retrieved compared to single aspiration in patients with poor…
- Conditions
- Low Ovarian Reserve, Poor Response to Ovulation Induction Poseidon Type IV, Poor Response to Ovulation Induction
- Trial name
- FLUSHING (NCT07270081)
- Testing
- follicular flushing, follicular aspiration
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Instituto Bernabeu
Ovarian Diseases, Fertility Issues
A Novel Ovarian Reserve Monitoring Algorithm for Patients at Risk of Ovarian Injury From Gonadotoxic Therapy
This is an observational cohort study to examine the use of a novel proposed ovarian reserve monitoring algorithm to (1) identify patients who are at risk of DOR and POI from gonadotoxic therapy, (2) minimize time from treatment…
- Conditions
- Ovarian Diseases, Fertility Issues, Gonadal Disorders
- Trial name
- MA (NCT05048654)
- Sponsor
- University of Colorado, Denver
Rheumatologic Diseases, Ovarian Reserve
Assessment of Ovarian Reserve in Women With Rheumatologic Diseases
Our infertility unit has started a clinic for women with rheumatological diseases. those women are prone to infertility problems and it might be due to their illness or cytotoxic treatment .
- Conditions
- Rheumatologic Diseases, Ovarian Reserve, Infertility
- Trial name
- NCT02273869
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Meir Medical Center
Crohn Disease
Thalidomide Results in Diminished Ovarian Reserve in Reproductive Age Female IBD Patients
The effectiveness of thalidomide in treating inflammatory bowel disease has been widely recognized. Meanwhile, many serious adverse drug reactions were notified， but no reports on ovarian reserve function.Therefore, this study…
- Trial name
- NCT02998827
- Testing
- Thalidomide, infliximab, azathioprine, enteral nutrition
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Activation of Primordial Follicles
Ovarian Needle Puncture for Follicle Activation in IVF Patients With Diminished Ovarian Reserve
Premature ovarian insufficiency (POI), is cessation of ovarian function characterized by hypergonadotropic amenorrhea and hypoestrogenic syndrome before 40 years of age.
- Trial name
- NCT04608695
- Testing
- Ovarian puncture
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Hacettepe University
Effects of Chemotherapy
The Longitudinal Ovarian Reserve Study
Postmenarchal female cancer patients scheduled to undergo cancer therapy may enroll in this study to assess changes in existing and novel surrogate measures of fertility potential before, during and after chemotherapy.
- Trial name
- NCT02395341
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania