Clinical trials: Ovarian Reserve
Fertility Awareness, Ovarian Reserve
Improving Women's Fertility Awareness and Reducing Anxiety Through Ovarian Reserve Screening and AI Counseling
This study evaluates the impact of preventive ovarian reserve screening and artificial intelligence (AI)-enabled counseling on fertility awareness and reproductive anxiety among women in Hong Kong.
- Conditions
- Fertility Awareness, Ovarian Reserve, Family Planning
- Trial name
- NCT07894302
- Testing
- AI-Enabled Fertility Counseling, Standard Educational Materials or PDF laboratory reports
- Where
- Hong Kong
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- City University of Hong Kong
Infertility, Obesity
Use of Pulsatile Intravenous FSH to Mitigate Reprometabolic Syndrome
Hypothesis: The investigators hypothesize that pulsatile FSH intravenous administration to women with obesity will correct the Reprometabolic Syndrome (RMS) luteal deficiency phenotype.
- Conditions
- Infertility, Obesity, Diminished Ovarian Reserve (DOR), Diminished Ovarian Reserve
- Trial name
- NCT06414096
- Testing
- Follicle Stimulating Hormone
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Diminished Ovarian Reserve, IVF
Study of G-CSF for DOR in Patients Undergoing IVF
Diminished ovarian reserve (DOR) is defined by reduced follicle counts in women, associated with decreased fertility and lower success rates with In Vitro Fertilization (IVF).
- Conditions
- Diminished Ovarian Reserve, IVF, G-CSF, Granulocyte Colony Stimulating Factor
- Trial name
- NCT07871825
- Testing
- Neupogen 300 μg subcutaneous injection, Subcutaneous injections of a saline solution
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Center for Human Reproduction
Ovarian Cysts, Endometriosis
Ovarian Reserve After Laparoscopic Cystectomy for Endometriotic and Non-Endometriotic Cysts
We will conduct this study to estimate the effect of laparoscopic cystectomy on ovarian reserve in endometriotic cysts versus non-endometriotic cysts.
- Conditions
- Ovarian Cysts, Endometriosis, Benign Ovarian Cyst, Ovarian Reserve
- Trial name
- NCT07686783
- Testing
- Laparoscopic Ovarian Cystectomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Benha University
Diminished Ovarian Reserve (DOR)
Guishen Yijing Granules for Diminished Ovarian Reserve With Kidney Deficiency Syndrome: A Randomized Controlled Trial
This study is a multicenter, stratified block-randomized, double-blind, double-dummy clinical trial designed to evaluate the efficacy and safety of Guishen Yijing Granules in patients with diminished ovarian reserve (DOR) and…
- Trial name
- NCT07841548
- Testing
- Guishen Yijing Granules, Coenzyme Q10 (drug)
- Volunteers
- 120 people
- Sponsor
- Shi Yun
Infertility, Female, Ovarian Reserve
hCG Priming in Women With Diminished Ovarian Reserve
The aim of this randomized controlled trial is to further examine the possible effects of low dose human chorionic gonadotropin (hCG) priming for eight weeks in women with diminished ovarian reserve (DOR) undergoing in vitro…
- Conditions
- Infertility, Female, Ovarian Reserve, In Vitro Fertilization (IVF)
- Trial name
- NCT07108621
- Testing
- Choriongonadotropin alfa (hCG)
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Kristine Loessl
Low Ovarian Reserve, Poor Ovarian Response
Ovulation Trigger Strategies in Low Ovarian Reserve (TRIGGERBEST)
This study aims to compare different ovulation triggering strategies in women with low ovarian reserve undergoing fresh in vitro fertilization (IVF) cycles.
- Trial name
- TRIGGERBEST (NCT07816562)
- Testing
- Human chorionic gonadotropin (hCG), Follitropin delta, Triptorelin
- Where
- Spain
- Volunteers
- 126 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Diminished Ovarian Reserve
Effect of Thumbtack Needle (TN) on Ovarian Reserve Function of Women With Diminished Ovarian Reserve (DOR)
Using a multi-center, large sample, randomized, patient-assessor blinded, sham-controlled clinical trial to evaluate the effect of thumbtack needle (TN) on ovarian function of patients with diminished ovarian reserve (DOR).
- Trial name
- TN-DOR (NCT05277948)
- Testing
- active TN and ETN treatment
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Dongmei Huang
Ovarian Reserve Markers, Ovarian Function
Ovarian Stromal Stiffness and Ovarian Reserve Parameters Via Transvaginal Shear Wave Elastography
This study aims to evaluate the relationship between ovarian stromal stiffness measured by transvaginal shear wave elastography (SWE) and conventional hormonal and ultrasonographic parameters of ovarian reserve.
- Conditions
- Ovarian Reserve Markers, Ovarian Function, Infertility, Anovulatory
- Trial name
- NCT07773337
- Testing
- Transvaginal Shear Wave Elastography
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Diminished Ovarian Reserve (DOR), Infertility (IVF Patients)
RCT Study on the Effect of ETN on Live Birth Rate in DOR Patients Undergoing IVF-ET
The goal of this clinical trial is to examine the effect of ETN on live birth rate in patients with diminished ovarian reserve (DOR) undergoing in vitro fertilizitaion-embryo transfer (IVF-ET).
- Trial name
- ETN-LBR-DOR (NCT07769684)
- Testing
- electro-thumbtack needle (ETN) / thumbtack needle (TN)
- Where
- 4 sites in China
- Volunteers
- 406 people
- Sponsor
- Huazhong University of Science and Technology
Diminished Ovarian Reserve (DOR)
Guishen Yijing Formula for Diminished Ovarian Reserve: A Real-World Retrospective Study
The goal of this observational study is to learn about the real-world effectiveness of Guishen Yijing Formula in women with diminished ovarian reserve (DOR).
- Trial name
- GSYJ;DOR (NCT07660692)
- Testing
- Guishen Yijing Formula(Chinese herbal decoction)
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Shi Yun
Diminished Ovarian Reserve (DOR)
Yulinzhu for Women With Diminished Ovarian Reserve
This is a randomized waiting-list controlled crossover trial carried out to investigate the efficacy of traditional Chinese medicine (TCM) for DOR and its potential beneficial effects on fertility.
- Trial name
- DOR (NCT07550998)
- Testing
- Yulinzhu (a Chinese Medicinal Formulae)
- Where
- 2 sites in Hong Kong
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Female Infertility, Reproductive Health
A Clinical Trial to Evaluate the Effects of a Supplement on Markers of Female Fertility
This study evaluates the effects of a daily dietary supplement (WeNatal For Her) on markers of female fertility, reproductive health, and sexual health over three menstrual cycles.
- Conditions
- Female Infertility, Reproductive Health, Fertility, Hormonal Imbalance
- Trial name
- NCT07740187
- Testing
- WeNatal For Her Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- WeNatal
Poor Ovarian Reserve, Infertility (IVF Patients)
Drospirenone-Primed Ovarian Stimulation Versus GnRH Antagonist Protocol in Poor Ovarian Responders Undergoing Freeze-All IVF/ICSI
Participants will: Take either drospirenone (a daily pill) or the standard daily injection during their ovarian stimulation cycle, alongside their regular fertility hormone injections Undergo egg retrieval, with all resulting…
- Trial name
- PPOS (NCT07736261)
- Testing
- Drospirenone drug, Cetrorelix 0.25 mg
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ahmed Saad
Diminished Ovarian Reserve (DOR)
Clinical Study on ShouTai Pills for Improving Reduced Ovarian Reserve
Grounded in the 'disease-syndrome combination' paradigm, this study endeavors to address the pivotal scientific issues pertaining to the clinical precision of Traditional Chinese Medicine (TCM) in managing Diminished Ovarian…
- Trial name
- NCT07737847
- Testing
- Shoutai Pill
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Peking Union Medical College Hospital
Endometriosis, Ovarian Reserve
Impact of Surgery for Deep Posterior Endometriosis on Ovarian Reserve (ENDORO)
Endometriosis is a chronic condition typically affecting women of reproductive age and often responsible for chronic pelvic pain and/or infertility. Its prevalence is estimated at 10% of the female population.
- Trial name
- ENDORO (NCT07469007)
- Testing
- pelvic ultrasound, Anti-Müllerian hormone assay, Questionnaire
- Where
- France
- Volunteers
- 100 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Female Infertility Due to Diminished Ovarian Reserve
Alpha-Lipoic Acid Supplementation and IVF Outcomes in Women of Advanced Maternal Age
Female fertility declines with advancing age, largely because of deteriorating oocyte quality driven by mitochondrial dysfunction and oxidative stress within the ovarian microenvironment.
- Trial name
- NCT07685431
- Testing
- Alpha-Lipoic Acid (ALA)
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Diminished Ovarian Reserve, Female Infertility
Hippo-Related Competing Endogenous RNA (ceRNA) Network Dysregulation and In Vitro Fertilization (IVF) Outcomes in Women With Diminished Ovarian Reserve
Diminished Ovarian Reserve (DOR) is an important cause of female infertility and is associated with poor ovarian response and lower pregnancy rates during In Vitro Fertilization (IVF).
- Conditions
- Diminished Ovarian Reserve, Female Infertility, In Vitro Fertilization
- Trial name
- DOR-HIPPO-IVF (NCT07658846)
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Diminished Ovarian Reserve
A Randomized Controlled Trial of Combined Bu Shen Yi Qi Decoction and Dehydroepiandrosterone (DHEA) for the Treatment of Ovarian Function Decline
The purpose of this clinical trial is to evaluate the efficacy and safety of Bushen Yiqi formula combined with dehydroepiandrosterone (DHEA) in the treatment of women with diminished ovarian reserve (DOR).
- Trial name
- NCT07535983
- Testing
- Bushen formula combined with dehydroepiandrosterone
- Where
- China
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Jiangxi University of Traditional Chinese Medicine
Female Fertility Decline, Diminished Ovarian Reserve
Early Prevention and Precision Management of Female Fertility Decline
Female fertility decline has become an important public health issue in China, with a substantial proportion of women of reproductive age experiencing reduced ovarian reserve.
- Conditions
- Female Fertility Decline, Diminished Ovarian Reserve, Reproductive Health, Infertility Prevention
- Trial name
- OvaRePred-Plus (NCT07581444)
- Testing
- Comprehensive Lifestyle Intervention, Routine Clinical Care
- Volunteers
- 384 people
- Sponsor
- Peking University Third Hospital