Clinical trials: Overweight and/or Obesity
Diabetes Mellitus, Type 2, Obesity
Effect of Roux-en-Y Gastric Bypass or Gastric Sleeve Surgery on Type 2 Diabetes
Roux-en-Y Gastric Bypass surgery (RYGB) ameliorates type 2 diabetes within days after surgery. Studies indicate that the gastric sleeve procedure has comparable effect on type 2 diabetes, but to what extent and how is not fully…
- Trial name
- NCT02713555
- Testing
- Roux-en-Y Gastric Bypass, Gastric Sleeve
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Obesity and Overweight
A Research Study of NNC0165-1875 Alone or Together With Semaglutide in People Who Are Overweight or Obese
The study is looking at possible new medicines for weight control in people with high body weight. The study looks at how the new medicines work in the body. The study consists of two parts.
- Trial name
- NCT03707990
- Testing
- NNC0165-1875, Semaglutide
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Depression, Depressive Disorder
Metformin as Adjunct Therapy in Depression-obesity Comorbidity: Clinical and Genetic Evaluation
The patients with depression and obesity will receive add-on metformin with antidepressant therapy, which may result in greater improvement in depressive symptoms and BMI reduction compared to antidepressant monotherapy.
- Conditions
- Depression, Depressive Disorder, Overweight or Obesity, Depressive Symptoms
- Trial name
- NCT07654179
- Testing
- Metformin, Antidepressant Therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Patients Who Gain Weight or Stop Losing Weight After barıatrıc Surgery, Absence of Cognitive or Psychiatric Illness
THE EFFECT OF MOTİVATİONAL INTERVİEWİNG-BASED MİNDFULNESS INTERVENTION ON WEİGHT MANAGEMENT AFTER WEİGT LOSS,7SLİMMİNG SURGERY: A RANDOMİZED CONTROLLED TRIAL.
Obesity is one of the most critical health problems in developed and developing countries, recognized as a chronic disease that adversely affects both individual and societal health.
- Conditions
- Patients Who Gain Weight or Stop Losing Weight After barıatrıc Surgery, Absence of Cognitive or Psychiatric Illness, Not Having Previously Received Cognitive Awareness Training, Not Having Undergone Revision Surgery
- Trial name
- NCT07351214
- Testing
- A MİNDFULNESS İNİTİATİVE BASED ON MOTİVATİONAL İNTERVİEWİNG
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Duygu Ateş
Polycystic Ovary Syndrome
Impact of Metformin in Teens With Polycystic Ovary Syndrome (PCOS) on Oral Contraceptive Therapy
Oral contraceptives are known to improve menstrual cycles and symptoms in PCOS, however may increase cholesterol. Metformin, a drug to improve insulin resistance, may benefit metabolic state.
- Trial name
- NCT00283816
- Testing
- Metformin, Oral Contraceptive Pill, Lifestyle Management Program
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Obesity, Infection; Cesarean Section
Skin Incisions and Wound Complication Rates for C-sections in Obese Women
It is the purpose of this study to evaluate the relationship between a low transverse, vertical midline, and supra-panicular high transverse skin incisions and the rate of wound complications in women with a BMI of 40 or greater…
- Conditions
- Obesity, Infection; Cesarean Section, Surgical Wound
- Trial name
- NCT02685761
- Testing
- Midline Vertical, High Transverse
- Where
- 7 sites in United States
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Obesity
Changing Eating Behaviors in Young Children: Should Healthy Foods be Increased or Unhealthy Foods Decreased?
Recommendations for treatment of childhood obesity in a primary care setting have been developed. These recommendations include beginning treatment with young children, focusing treatment on the parent so the parent can assist…
- Trial name
- NCT00200265
- Testing
- diet
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Anxiety, Wellness, Psychological
Community Park-Based Programs for Health Promotion: The Fit2Lead Prospective Cohort Study
The Fit2Lead prospective cohort study examines the effects of a park-based youth mental health and resilience afterschool program on youth participant mental health, resilience, physical fitness, and violence prevention outcomes.
- Conditions
- Anxiety, Wellness, Psychological, Overweight or Obesity, Hypertension
- Trial name
- F2L (NCT06596265)
- Testing
- Fit2Lead Group 1-2
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Healthy Lifestyle, Health Behavior
Better App: (Further-)Development and Evaluation of a Digital Lifestyle Programme
In recent years, we developed and evaluated personalised lifestyle interventions, the BETTER programmes (BETER in Dutch, acronym for Move, Eat, Change).
- Trial name
- BETTERapp (NCT05837468)
- Testing
- BETTERapp
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Zuyd University of Applied Sciences
Adiposity, Metabolic Syndrome
Meta-analysis of Low-calorie Sweetened Beverages and Cardiometabolic Outcomes
We propose to conduct a systematic literature review and meta-analysis to assess the association of low-calorie sweetened beverages (LCSBs) on cardiometabolic outcomes in prospective cohort studies.
- Conditions
- Adiposity, Metabolic Syndrome, Type 2 Diabetes, Cardiovascular Diseases
- Trial name
- NCT04245826
- Testing
- Change in LCSBs Intake, Substitute LCSBs for SSBs or Water
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity, Childhood, Pediatric Obesity
Treatment Efforts Addressing Child Weight Management by Unifying Patients, Parents & Providers
The US Preventive Services Task Force (USPSTF) recommends that providers screen children aged 6 years and older for obesity and offer or refer them to a comprehensive behavioral intervention (≥26 hours over a period of up to 12…
- Conditions
- Obesity, Childhood, Pediatric Obesity, Childhood Obesity, Adolescent Obesity
- Trial name
- TEAM UP (NCT03843424)
- Testing
- eSOC program, FBT program
- Where
- 7 sites in United States
- Volunteers
- 1,460 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Diet Habit
Family and Web-based Nutrition Intervention to Increase Vegetable, Fruit, and Dairy Intakes in Children
Considering the high prevalence of childhood obesity worldwide, effective interventions are needed . Parental involvement in interventions and the use of web-based modalities appear to be promising approaches.
- Trial name
- NCT03798808
- Testing
- Consumption of fruits, vegetables and dairy products
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Laval University
Type 2 Diabetes
Middle-School Based Primary Prevention Trial of Type 2 Diabetes
HEALTHY was a primary prevention trial conducted in 42 middle schools at 7 locations across the US to impact risk factors for type 2 diabetes in adolescents.
- Trial name
- HEALTHY (NCT00458029)
- Testing
- integrated program of nutrition, activity, behavior, and promotion
- Where
- 8 sites in United States
- Volunteers
- 4,603 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Adiposity, Insulin Resistance
PREterM FOrmula Or Donor Breast Milk for Premature Babies
In order to address this crucial question, central to preterm newborn care, a multicentre United Kingdom (UK) -wide study randomising 4000 preterm babies would be necessary to achieve sufficient power to evaluate the impact on…
- Conditions
- Adiposity, Insulin Resistance, Metabolomic Profile, microRNA Profile
- Trial name
- PREMFOOD (NCT01686477)
- Testing
- Unfortified Human donor Milk used to make up any shortfall in mother's own milk, Fortified Human donor Milk used to make up any shortfall in mother's own milk, Preterm Formula used when there is a shortfall in mother's own milk
- Where
- United Kingdom
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Pediatric Obesity
Efficacy of a School-based Obesity Prevention Program in Mexican Schoolchildren: Cluster Randomized Controlled Trial
There is evidence that obesity prevention programs show positive effects on obesity and lifestyle parameters. However, the effect of the programs delivered by different implementers is unknown, and in Mexico, the available…
- Trial name
- NCT05461703
- Testing
- Planet Nutrition Program
- Where
- Mexico
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Universidad de Sonora
Metabolic Disease, Obesity
Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System
Background: Researchers are interested in studying individuals who have known or suspected metabolic, inflammatory or genetic diseases that may put them at a high risk for heart diseases or diseases of their blood vessels.
- Conditions
- Metabolic Disease, Obesity, Li-Fraumeni Syndrome, Cardiomyopathy
- Trial name
- NCT01143454
- Testing
- NSR IDE-MRI: Research pulse sequences
- Where
- 3 sites in United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Obesity, Type 2 Diabetes
Strength Training and Nutrition Development for African American Youth
The investigators are conducting an intervention study to examine the effects of a 16-week exercise and diet interventions on prevention of disease, specifically type 2 diabetes and heart disease, in African American youth.
- Conditions
- Obesity, Type 2 Diabetes, Cardiovascular Risk, Cancer
- Trial name
- STAND (NCT01441323)
- Testing
- Nutrition, Strength Training & Nutrition
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Pediatric Obesity
Pediatric Quality of Life Among Population With Body Mass Index (BMI) Greater Than or Equal to 85%
We are currently experiencing an epidemic of obesity in the Pediatric Population. This epidemic affects many areas including quality of life. We have been conducting a nutrition and exercise program since 2003.
- Trial name
- NCT00714870
- Testing
- Behavioral nutrition and exercise program
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Steward St. Elizabeth's Medical Center of Boston, Inc.
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Pregnancy, Obesity
Investigation of Continuous Versus Interrupted Subcutaneous Fat Closure in Reducing Surgical Site Infection
This research aims to clarify the best way to perform subcutaneous tissue closure in overweight and obese patients undergoing caesarean section to reduce the occurrence of surgical site infections.
- Trial name
- NCT05856968
- Testing
- continuous subcutaneous tissue closure, Interrupted subcutaneous tissue closure
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies