Clinical trials: Ovulation
Observational Study, Dydrogesterone
Observational Study of Dydrogesterone in Cycle Regularization
Dydrogesterone has been widely used worldwide for various gynecological and obstetric indications: Dydrogesterone is effective in cycle regulation treatment.
- Conditions
- Observational Study, Dydrogesterone, Irregular Menstrual Cycle, Abnormal Uterine Bleeding
- Trial name
- NCT02029144
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Fudan University
Low Ovarian Reserve, Poor Response to Ovulation Induction Poseidon Type IV
Follicular Flushing Using Double Lumen Needle Versus Direct Aspiration in Low Prognosis Patients According to the POSEIDON Criteria
This is a prospective, randomized, controlled clinical trial designed to evaluate whether follicular flushing increases the number of cumulus-oocyte complexes (COCs) retrieved compared to single aspiration in patients with poor…
- Conditions
- Low Ovarian Reserve, Poor Response to Ovulation Induction Poseidon Type IV, Poor Response to Ovulation Induction
- Trial name
- FLUSHING (NCT07270081)
- Testing
- follicular flushing, follicular aspiration
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Instituto Bernabeu
Ovulation Induction, Infertility
An Open Label, Canadian Phase IIIb Study With Ovidrel in Ovulation Induction (OI) and Assisted Reproductive Technique (ART)
With the development of the recombinant gonadotrophins, the use of human source proteins for the production of hormones has become unnecessary.
- Trial name
- NCT01152866
- Testing
- Choriogonadotropin alpha (r-hCG)
- Volunteers
- 3 people
- Sponsor
- EMD Serono
IVF, Infertility
Second Ovulation Induction
Studies reported various risk factors for inadequate ovulation induction such as body mass index, low ovarian reserve, low baseline FSH and LH, and previous use of contraception or agonist.
- Trial name
- NCT06502665
- Testing
- Women having had second ovulation induction after failed oocyte pick-up
- Where
- Canada
- Volunteers
- 87 people
- Sponsor
- Clinique Ovo
PCO, Induction of Ovulation
Parameters Declaring PCO Infertile Patients Either Sensitive or Resistant to Different Doses of Clomiphene Citrate.
Polycystic ovary syndrome (PCOS) is a common endocrinological disorder seen in 6%-10% of women (Human Reproduction, 2004). It is characterized by polycystic ovaries, anovulatory cycles, and hyperandrogenism.
- Conditions
- PCO, Induction of Ovulation, Clomiphene Citrate
- Trial name
- NCT04887402
- Testing
- Clomiphene Citrate
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Polycystic Ovary Syndrome, Puberty Disorders
Does Treatment of Androgen Excess Using Spironolactone Improve Ovulatory Rates in Girls With Androgen Excess?
Adolescent girls with androgen excess have a higher rate of irregular periods and decreased ovulation rates compared to normal girls, and are considered at-risk for developing polycystic ovary syndrome (PCOS).
- Conditions
- Polycystic Ovary Syndrome, Puberty Disorders, Ovulation Disorder
- Trial name
- CBS009 (NCT04075149)
- Testing
- Spironolactone
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Virginia
Abnormal Uterine Bleeding (AUB), Ovulation Dysfunction
Clinical Efficacy And Safety of Dydrogesterone In The Treatment Of Abnormal Uterine Bleeding During Puberty
This multicenter prospective cohort study evaluates the clinical efficacy and safety of dydrogesterone versus drospirenone and ethinylestradiol in adolescents aged 10-19 years with abnormal uterine bleeding-ovulatory dysfunction…
- Trial name
- NCT07703488
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Guangdong Women and Children Hospital
Infertility
36 Versus 42 Hour Time Interval From Ovulation to Intrauterine Insemination
The purpose of this study is to prove that a higher clinical pregnancy rate can be achieved with a 42 to 44 hour time interval between ovulation trigger and intrauterine insemination than a 36 to 38 hour time interval in…
- Trial name
- NCT02210611
- Testing
- Intrauterine Insemination 36 hours, Intrauterine Insemination 42 hours
- Where
- Israel
- Volunteers
- 71 people
- Sponsor
- HaEmek Medical Center, Israel
Fertility, Mobile Applications
Smartphone vs Manual Interpretation of Biomarkers for Ovulation and Luteal Phase Detection (SMOM Study)
This study will compare different combinations of fertility signs (cervical mucus (CM), luteinizing hormone [LH], pregnanediol glucuronide [PDG], and basal body temperature [BBT]) to determine which are most reliable for…
- Conditions
- Fertility, Mobile Applications, Artifical Intelligence, Cervical Mucus
- Trial name
- SMOM (NCT07248046)
- Testing
- Premom App-Assisted Fertility Tracking
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bruyère Health Research Institute.
Luteal Phase Insufficiency
Early Luteal Phase Progesterone Kinetics After hCG-Induced Ovulation in Modified Natural Cycle
This pilot study evaluates how progesterone levels change after hCG-triggered ovulation in modified natural cycles. Forty women preparing for frozen embryo transfer will have blood tests over 6 days to monitor hormone levels.
- Trial name
- CineP4 (NCT07028710)
- Testing
- hCG
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Neonatal SEPSIS, Perinatal Mortality
Outcomes in Spontaneous and ART Twin Pregnancies
During the last decades, assisted reproductive technique has been transformed from a miracle to real and has become widely used for treatment human infertility. this was associated with increased the rate of twin pregnancies
- Conditions
- Neonatal SEPSIS, Perinatal Mortality, Maternal Morbidity
- Trial name
- NCT03590483
- Where
- Iraq
- Volunteers
- 200 people
- Sponsor
- Hawler Medical University
PCOS
Clomiphene Citrate Versus Tamoxifen for Ovulation Induction in PCOs
Comparison between Clomiphene citrate and Tamoxifen for induction of ovulation in women with PCOS.
- Trial name
- NCT02479256
- Testing
- Clomiphene citrate, Tamoxifen
- Where
- Egypt
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Ovarian Response
The Effect of Oxytocin (OT) and Oxytocin Plus Human Chorionic Gonadotropin (hCG), in Cycles Induced by Letrozole or Clomiphene Citrate
The specific aims of this study were to assess whether letrozole as an aromatase inhibitor plus hCG or OT alone, or in combination compared with CC, improves ovarian response.Ethical design of this study is based on the ethical…
- Trial name
- NCT00844350
- Testing
- letrozole , oxytocin,hCG,clomiphene citrate
- Volunteers
- 177 people
- Sponsor
- Tabriz University
Ovulation Induction
A Prospective, Multi-centric Observational Study to Determine the Mono-bifollicular Development in Infertile Women Subjected to Ovulation Induction With Follitropin α
This is a prospective and multicentric observational study to determine the real mono-bifollicular development rate that is obtained under normal care conditions following ovulation induction (OI) treatment with follitropin-alpha…
- Trial name
- P450 (NCT01111084)
- Testing
- Follitropin alpha (r-FSH)
- Where
- Spain
- Volunteers
- 410 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
PCOS, Myo-inositol-resistance
Myo-inositol Plus Alpha-lactalbumin in PCOS Myo-inositol-resistant Patients
The investigator's aim is to evaluate if the combination of myo-inositol and alpha-lactalbumin can overcome the resistance to myo-inositol in PCOS patients
- Trial name
- NCT03667443
- Testing
- Myo-inositol + folic a. + α-lactalbumin, Myo-inositol + folic a.
- Where
- Bulgaria
- Volunteers
- 50 people
- Sponsor
- Lo.Li.Pharma s.r.l
Polycystic Ovary Syndrome
Coenzyme Q10 and Clomiphene Citrate (CC) for Ovulation Induction in Polycystic Ovary Syndrome
Objective of the study was to evaluate the effect of combination of oral Coenzyme Q10 (CoQ10), with clomiphene citrate (CC) for ovulation induction in CC-resistant polycystic ovary syndrome (PCOS).In a prospective controlled…
- Trial name
- NCT01910766
- Testing
- Coenzyme Q10, clomiphene citrate
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Obese
Role of Semaglutide in Restoring Ovulation in Youth and Adults With Polycystic Ovary Syndrome
Girls and women 12-35 years old with obesity and polycystic ovarian syndrome who are on or off metformin, will receive a glucagon like peptide-1 receptor agonist intervention for 10 months to induce metabolic changes, weight loss…
- Trial name
- RESTORE (NCT05819853)
- Testing
- Semaglutide Injectable Product (Wegovy and/or Ozempic)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Colorado, Denver
Ovulation
Study Evaluating Effects of Levonorgestrel and Ethinyl Estradiol on Ovulation
To determine the ability of a monophasic oral contraceptives ("OC") regimen of Levonorgestrel ("LNG") 90 mg and Ethinyl Estradiol ("EE") 20 mg to inhibit ovulation during 84 days of continuous therapy.
- Trial name
- NCT00254189
- Testing
- Levonorgestrel, Ethinyl Estradiol
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Infertility
Comparison of Assisted Reproductive Technology (ART) Outcomes Between Two Protocols of Induction of Ovulation in Patients With Hypogonadotropic Hypogonadism
We wanted to compare the Assisted Reproductive Technology (ART) outcomes between two protocols of induction of ovulation in patients with Hypogonadotropic Hypogonadism.
- Trial name
- NCT02140515
- Testing
- Lutropin alfa, Follitropin alfa and Lutropin alfa
- Where
- Iran
- Volunteers
- 90 people
- Sponsor
- Royan Institute
Menstruation
Cycle and Ovulation Study Expansion
The objective of this study was to collect menstrual cycle, health sensor data and general health information to understand correlations between menstrual cycle and health sensor data, and how those correlations may be affected…
- Trial name
- NCT05852951
- Where
- United States
- Volunteers
- 698 people
- Sponsor
- Apple Inc.