Clinical trials: Ozone
Primary Apical Periodontite
Ozone Therapy in Endodontic Practice, in Vivo Study
The ozone therapy has been coming up as a new therapeutic modality. Medicine has been practicing since XIX century and counted great results. It is indicated for the treatment of 260 different pathologies.
- Trial name
- NCT00946634
- Testing
- Ozone, Control (no last irrigation), Aqueous Ozone
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Post-ischemic Stroke Insomnia
Ozone Autohemotherapy for Ischemic Stroke Sleep Disorder
The purpose of this study is to observe the efficacy and safety of ozonated autohemotherapy in patients of post-ischemic stroke insomnia and to explore its mechanism of action.
- Trial name
- NCT05508113
- Testing
- ozone autohemotherapy
- Where
- 2 sites in China
- Volunteers
- 65 people
- Sponsor
- Mengmeng Chen
Ozone, Caries
Effectiveness of the Ozone Application in Two-Visit Indirect Pulp Therapy of Permanent Molars With Deep Carious Lesion
The aim of this study was to evaluate the clinical and microbiological effectiveness of the ozone application in two-visit indirect pulp therapy.
- Trial name
- ozone (NCT03693066)
- Testing
- Ozone, chlorhexidine digluconate, Control
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Dental Caries
Healozone Study to Evaluate the Safety and Efficacy of the Use of Ozone for Management of Dental Caries
Caries means demineralization with the formation of cavities and pulp symptoms and necrosis as an end result. The acids in the mouth are mainly produced by oral bacteria like Streptococcus mutans from bacterial biofilms adhering…
- Trial name
- NCT00495495
- Testing
- Ozone treatment
- Where
- 3 sites in United States
- Volunteers
- 394 people, healthy volunteers welcome
- Sponsor
- Indiana University
Rectal Ozone, Neuroprotector
Rectal Ozone as Neuroprotector Post CNS Insult in Children
This study aims to evaluate the efficacy of rectal ozone therapy as a neuroprotective modality in Pediatric acquired brain injury.
- Conditions
- Rectal Ozone, Neuroprotector, CNS, Insult
- Trial name
- NCT07153627
- Testing
- Rectal ozone sessions, Conventional rehabilitation program
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Al-Azhar University
Periodontal Pocket, Periodontitis
Use of Ozone Gel as an Antimicrobial in Treatment of Periodontitis
Periodontitis is an inflammatory disease that destroys tooth-supporting structures through oral bacterial plaque. ozone gel's act as an antimicrobial effect as an adjunct to conventional periodontal therapy (scaling and root…
- Trial name
- NCT05905445
- Testing
- ozone gel
- Where
- Iraq
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Ghufran Falih Hassan
Chronic Hepatitis B
A Control Study to Evaluate The Efficacy And Safety of Ozone-therapy in Chronic Hepatitis B
The purpose of this study is to investigate the efficacy and safety of medical ozone in treatment of chronic hepatitis B patients.
- Trial name
- NCT01887275
- Testing
- medical ozone therapy with humares, conventional interferon-α
- Where
- China
- Volunteers
- 439 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Research on the Effectiveness of a Corticosteroid, Single Dose and Three Doses of Ozone Injection in Shoulder Impingement Syndrome
Ozone Injection for Shoulder Impengement Syndrome
Ozone injection has lately been utilized as a safe alternative to corticosteroids in the management of musculoskeletal diseases with fewer side effects.
- Trial name
- NCT05304884
- Testing
- combined oxygen-ozone and corticosteroid
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Erzurum Regional Training & Research Hospital
Pulpitis - Irreversible, Ozone
Zinc Oxide Ozonated Olive Oil in LSTR
This study will be carried out to evaluate and compare the clinical and radiographic effect of zinc oxide-ozonated olive oil (ZnO-OO) versus Modified Triple Antibiotic Paste (MTAP) as a Lesion Sterilization and Tissue Repair…
- Conditions
- Pulpitis - Irreversible, Ozone, Pulp Disease, Dental, Primary Teeth
- Trial name
- Zn-OO/MTAP (NCT06854744)
- Testing
- lesion sterlization and tissue repair, Zinc Oxide Ozonated Oil, Modified Triple Antibiotic Paste
- Where
- 2 sites in Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanta University
Caries,Dental
Ozone Application Before Fissure Sealants
Decay is a multifactorial infective degenerative disease of hard dental tissues, caused by Streptococcus mutans and Lactobacillus forming the bacterial biofilm of teeth surfaces.
- Trial name
- NCT04040920
- Testing
- Ozone, Pits and fissure sealants
- Where
- Italy
- Volunteers
- 67 people
- Sponsor
- IRCCS Burlo Garofolo
Denture Stomatitis
Ozonated Water in Treatment of Denture Stomatitis
The effect of Ozonated water on the treatment of oral stomatitis associated with complete denture wearer in comparison to Chlorhexidine mouthwash
- Trial name
- NCT06021847
- Testing
- Ozonated water, Chlorhexidine mouthwash
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- National Research Centre, Egypt
White Spot Lesion of Tooth
Fluoride Varnish, Ozone, Octenidin and WSLs in Orthodontic Patients
Objectives: to assess the efficiency of four prophylactic protocols on white spot lesions during orthodontic treatment: 1. professional mechanical tooth cleaning (PMTC)+fluoride varnish, 2.
- Trial name
- NCT04992481
- Testing
- PMTC, fluoride varnish, gaseous ozone therapy
- Volunteers
- 150 people
- Sponsor
- Pomeranian Medical University Szczecin
Chronic Inflammatory Gingival Enlargement, Gingival Enlargement
Wound Healing After Gingivectomy
Gingival enlargement caused by chronic inflammation may require surgical intervention when non-surgical periodontal therapy is insufficient.
- Conditions
- Chronic Inflammatory Gingival Enlargement, Gingival Enlargement, Gingival Hyperplasia
- Trial name
- OZONE-GING (NCT07517328)
- Testing
- Gaseous ozone application, Gingivectomy/gingivoplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ataturk University
Keratitis
Ozone-based Eye Drops as Adjuvant Therapy in Microbial Keratitis
To compare the therapeutic effect of ozone-based eye drops as an adjuvant therapy to that of the conventional topical antimicrobial agents in patients with microbial keratitis .
- Trial name
- NCT05689996
- Testing
- Ozone-Based Agent
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Acute Exacerbation Copd
Impact of Air Quality on Exacerbations of COPD in the Somme
All COPD patients with a diagnosis of acute exacerbation in emergency room in University Hospital of Amiens-Picardie between 01/01/2017 and 31/12/2017.
- Trial name
- PolluBPCO (NCT03079661)
- Where
- France
- Volunteers
- 179 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Dental Caries
Ozonized Gel vs Gaseous Ozone Against S. Mutans in Deciduos Molars Caries
The aim of this study is to verify, through bacteriological analysis, the efficacy of reducing the bacterial load referred to the presence of Streptococcus Mutans in carious lesions of viable deciduous molars by application of…
- Trial name
- NCT06641323
- Testing
- Ozonized gel, Ozonized water
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- University of Pavia
Myofascial Pain Syndromes
Effect of Lidocaine and Ozone in Injection for Myofascial Pain
Myofascial pain syndrome (MPS) is a chronic soft tissue rheumatism characterized by tense, painful muscle bands, known as trigger points, located within the muscle or fascia.
- Trial name
- NCT06768281
- Testing
- Headache Impact Test-6 (HIT-6), Pittsburgh Sleep Quality Index (PSQI), Visual Analogue Score (VAS)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yağmur Malkoc
Chronic Hepatitis B
Efficacy of Medical Ozone Therapy in Patients With Chronic Hepatitis B
The purpose of this study is to verify the effectiveness and safety of medical ozone therapy system in treatment of chronic hepatitis B.
- Trial name
- EMOTCHB (NCT01342185)
- Testing
- medical ozone therapy with tianyi, medical ozone therapy with humares, Diammonium glycyrrhizinate Capsules
- Where
- China
- Volunteers
- 189 people
- Sponsor
- Nanfang Hospital, Southern Medical University
COVID-19 Pneumonia
Ozone Therapy and Coronavirus Disease of 2019 (COVID-19) Pneumonia
The objective is to determine whether the use of ozone autohemotherapy is associated with a decrease in time to clinical improvement
- Trial name
- NCT04444531
- Where
- Spain
- Volunteers
- 18 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Deep Caries, Ozone
Influence of Ozone Application in Stepwise Excavation Procedure of Primary Molars With Deep Carious Lesion
Purpose: The purpose of this study was to investigate the clinical and microbiological effectiveness of the ozone application in stepwise excavation of primary molars.
- Trial name
- NCT03737201
- Testing
- ozone, chlorhexidine digluconate, Control
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University