Clinical trials: PRF
Revascularization of Immature Young Permenant Teeth
Compare Between the Effect of CGF and PRF on Revascularization of Immature Roots of the Mandibular Permanent First Molar
in this study investigators do revascularization technique to promote root growth of immature mandibular first permanent molar by using CGF and PRF from blood sample of patients
- Trial name
- NCT07460869
- Testing
- Revascularization/Conservative management
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Malocclusion, Angle Class II, Division 1
Efficacy of Biological Technique in Upper Canine Retraction and Levels of Discomfort
Twenty patients need therapeutic extraction of the maxillary first premolars with subsequent retraction of the maxillary canines, will be divided randomly into two groups, and will randomly assigned to one side of the maxillary…
- Trial name
- NCT03399422
- Testing
- i-PRF, canine retraction
- Where
- Syria
- Volunteers
- 20 people
- Sponsor
- Damascus University
Root Resorption
Treatment of Internal Inflammatory Root Resorption Using Injectable PRF Revascularization Technque
Currently Endodontics looks forward for regeneration rather than repair. Regenerative endodontic therapy was limited to pulp revascularization of necrotic pulp in immature teeth , followed by mature teeth.
- Trial name
- NCT04410679
- Testing
- injectable PRF
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Endodontic Inflammation
Regenerative Endodontic Procedure of Immature Permanent Teeth With L-PRF: a Pilot Controlled, Clinical Trial
This study evaluates the impact of autologous 'leucocyte and platelet rich fibrin' (L-PRF) on the periapical bone healing and further root development of infected immature permanent teeth.
- Trial name
- NCT02437708
- Testing
- REP with L-PRF, REP, stem and progenitor cells
- Where
- 4 sites in Belgium
- Volunteers
- 29 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Pulpitis - Irreversible, Apical Periodontitis
Evaluation of Nano Bioactive Glass Combined With i-PRF Scaffold in Vital Pulp Treatments
With consideration of the previous studies regarding the properties of i-PRF, it will be used in combination with another bioactive material: (Nano-BAG) versus using of i-PRF only as a pulpotomy material with using a premixed…
- Trial name
- NCT05902936
- Testing
- Pulpotomy for mature permanent mandibular molars
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Neuritis
Role of PRF With MTA and Theracal After Pulpotomy in Relieving Pain
this research will evaluate the effect of PRF with different bioactive materials in dentistry
- Trial name
- NCT03493321
- Testing
- PRF with Theracal
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Cairo University
Intrabony Periodontal Defects
Minimally Invasive Non Surgical Treatment Using Injectable Platelet Concentrate in Treatment of Deep Pockets.
The purpose of this study is to evaluate change in pocket depth following using minimally invasive non surgical combined with injectable platelet concentrate .
- Trial name
- NCT07722390
- Testing
- Injectable PRF, MINST
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Congenital Diaphragmatic Hernias
Contribution of PRF in CDH in Children With Prothetic Patch Closure
Improved management of giant congenital diaphragmatic hernias (CDH) in neonates : decreased risk of morbidity and mortality due to prosthesis release.
- Trial name
- HECODIAP (NCT03861182)
- Testing
- Biological functionalization of the prosthetic materials by PRF
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Apicomarginal Defects
Evaluate the Effect of Graft and Membrane on Healing of Apicomarginal Defects
This study will compare the effect of guided tissue regeneration using a mixture of autograft and PRF covered with a collagen membrane as compared to the membrane alone in the healing of apicomarginal defects.
- Trial name
- NCT04366700
- Testing
- Periapical surgery with autograft and collagen membrane, Periapical surgery with collagen membrane
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Ridge Preservation
E-PRF vs Collagen Membranes in Ridge Preservation
Dental implants are often considered the gold standard to replace missing teeth. Having success with dental implants depends on the hard tissue and soft tissue remaining after tooth extractions.
- Trial name
- NCT07281053
- Testing
- Barrier membrane for ridge preservation
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Center for Advanced Rejuvenation and Esthetics
Cleft Palate, Unilateral Cleft Palate
Palatoplasty Techniques Using PRF and Gentamicin-Loaded PRF in Cleft Palate
This prospective, randomized controlled trial evaluates the clinical efficacy of autologous Platelet-Rich Fibrin (PRF) and Gentamicin-Loaded PRF as regenerative and antimicrobial biological adjuncts in primary palatoplasty.
- Conditions
- Cleft Palate, Unilateral Cleft Palate, Bilateral Cleft Palate, Complete Cleft Palat
- Trial name
- NCT07752849
- Testing
- Standard palatoplasty ( control), Platelet _ Rich Fibrin ( PRF), gentamicin_ loaded PRF
- Where
- Yemen
- Volunteers
- 90 people
- Sponsor
- Al-Thawra Modern General Hospital
Effects of; Movement of Teeth Assiste Wit MOPS and I-prf
Maxillary Canine Retraction Assisted With Micro-osteoperforations Versus Injectable Platelet Rich Fibrin
The present clinical comparative study will be undertaken for assessment of two different modalities of maxillary canine retraction assisted with microosteoperforations versus injectable platelet rich fibrin.
- Trial name
- NCT05960825
- Testing
- injectable platelet rich fibrin versus microosteoperforation
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Orthodontic Pathological Resorption of External Root
Efficacy of Injection Platelet-rich Fibrin(I-PRF) in Accelerate Alignment and Leveling
the aim of this study is to evaluate the effectiveness of injection I-PRF to accelerate alignment and leveling of the upper anterior teeth and reduce the time required for treatment.
- Trial name
- NCT04885842
- Testing
- injection I-PRF
- Where
- Syria
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Latakia University
Endodontics, Regenerative Endodontic Procedures
The Effect of Using Different Scaffolds in Retreated Teeth on The Clinical and Radiological Success of Regenerative Endodontic Treatment
This clinical study aims to compare the clinical and radiographic outcomes of four different scaffolds used in regenerative endodontic treatment of previously root canal-treated permanent teeth requiring retreatment.
- Conditions
- Endodontics, Regenerative Endodontic Procedures, PRF, i-PRF
- Trial name
- NCT07721051
- Volunteers
- 60 people
- Sponsor
- Kırıkkale University
Dental Pulp Necroses
Efficacy of Regenerative Endodontic Treatment With PRF as a Secondary Treatment of Mature Necrotic Incisors in Adolescents
Evalaution of clinical success of secondary treatment for total 40 permanent incisors with failed root canal treatment with apical radiolucency.
- Trial name
- PRF (NCT05517187)
- Testing
- no intervention, Platelet rich fibrin
- Where
- 2 sites in Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nahda University
Apico Marginal Defects
Comparative Evaluation of Two PRF Formulations on Quality of Life and Healing of Apicomarginal Defects
Healing of apicomarginal defects using 2 different formulations of PRF i.e PRF -high and PRF-medium will be assessed and compared using 2D and 3D criteria.
- Trial name
- NCT04396743
- Testing
- Periapical surgery with use of prf-high clot and membrane, Periapical surgery with use of prf-medium clot and membrane
- Where
- India
- Volunteers
- 32 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Gingival Recession Types One(RT1), Gingival Crevicular Fluid
Comparison of Connective Tissue and PRF in Gingival Recession
Aim: In this study, it was aimed to comparatively investigate the clinical and biochemical effects of subepithelial connective tissue graft and coronally advanced flap (SCTG + CAF) or titanium-prepared platelet rich fibrin and…
- Trial name
- NCT07877064
- Testing
- Titanium-prepared Platelet-Rich Fibrin, SCTG + CAF
- Volunteers
- 22 people
- Sponsor
- Ataturk University
Pulp Necrosis, Immature Permanent Teeth
PRF and CGF Scaffolds With EDTA in Regeneration
This study evaluated the regenerative outcomes of immature permanent teeth with necrotic pulps treated using three scaffold types-blood clot, platelet-rich fibrin (PRF), and concentrated growth factor (CGF)-combined with either…
- Conditions
- Pulp Necrosis, Immature Permanent Teeth, Open Apex, Periapical Periodontitis
- Trial name
- RET-EDTA-CGF (NCT07265804)
- Testing
- Blood Clot + 5% EDTA, Blood Clot + 17% EDTA, PRF + 5% EDTA
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Wound Heal
The Effects Of I-PRF On Gingivectomy and Gingivoplasty
The study aims to evaluate the effects of injectable platelet-rich fibrin (I-PRF) applications on early wound healing after gingivectomy and gingivoplasty surgery.
- Trial name
- NCT05871190
- Testing
- İnjectable platelet rich fibrin, Gingivectomy anad gingivoplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Necrotic Immature Permanent Teeth, Regenerative Endodontic Treatment
Application of Advanced Platelet-Rich Fibrin Plus (A-PRF+) in Revascularisation of Necrotic Immature Permanent Teeth
The goal of this clinical trial is to evaluate the effectiveness of an advanced platelet-rich fibrin plus (A-PRF+) revascularization procedure to promote healing and root development in necrotic immature permanent single-rooted…
- Conditions
- Necrotic Immature Permanent Teeth, Regenerative Endodontic Treatment, Pulp Regeneration, Root Maturation
- Trial name
- A-PRF+ (NCT07092488)
- Testing
- Advanced Platelet-Rich Fibrin Plus (A-PRF+) Revascularization Procedure
- Where
- Croatia
- Volunteers
- 28 people
- Sponsor
- University of Zagreb