Clinical trials: Pain Cancer
Breakthrough Pain, Palliative Medicine
Paediatric Breakthrough Pain Assessment
Many children and young people with life-limiting and life-threatening illnesses get sudden bursts of pain called breakthrough pain. At the moment, there aren't any good ways to measure this pain in children and young people.
- Conditions
- Breakthrough Pain, Palliative Medicine, Oncology Pain, Pediatric ALL
- Trial name
- BEACON (NCT06790719)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Pediatric Cancer
The Effect of Biofeedback-Based Virtual Reality Game on Children
The needles of port catheters, which are often used in childhood cancer treatment, must be changed every 5-7 days, which causes pain, anxiety, and fear in children every 5-7 days In recent years, the usage of virtual reality has…
- Trial name
- NCT05585840
- Testing
- Biofeedback-based virtual reality game
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Koç University
Pain, Anxiety
The Effect of Cartoon Watching During Central Venous Catheter Dressing Changes in Children With Cancer
Many medical interventions, including dressing change of central venous catheters, can cause anxiety and pain in children with cancer.
- Trial name
- NCT05301374
- Testing
- Watching Cartoon
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Mehmet Akif Ersoy University
Cancer
Using Virtual Reality to Reduce Procedural Pain in Children With Cancer
This study will assess the impact of virtual reality (VR) in decreasing procedural pain related to subcutaneous port (SCP) access in children with cancer.
- Trial name
- NCT02929771
- Testing
- Samsung GearVR, iPad
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- The Hospital for Sick Children
Orchiectomy, Spermatic Cord Block
Comparison of Spinal Anesthesia and Spermatic Cord Block for Bilateral Orchiectomy
The goal of this randomized controlled trial is to compare intraoperative pain score, Morphine consumption during 6 and 12 hour after surgery, and postoperative complications between SA and SCB groups in metastatic prostate…
- Conditions
- Orchiectomy, Spermatic Cord Block, Spinal Anesthesia, Pain Score
- Trial name
- NCT06313775
- Testing
- bilateral orchiectomy
- Where
- Thailand
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Sanpasitthiprasong Hospital
Pain
Pharmacokinetics & Safety of Diclofenac Potassium Oral Solution in Ped. Subjects (2-12 Yrs) With Mild-Mod. Acute Pain
As part of the Pediatric Research Equity Act (PREA) commitment, the objectives of the study are to characterize the pharmacokinetic (PK) profile and to determine the safety and tolerability of diclofenac potassium oral solution…
- Trial name
- NCT02287350
- Testing
- diclofenac potassium oral solution
- Where
- 5 sites in United States
- Volunteers
- 51 people
- Sponsor
- Depomed
Chronic Pain, Chronic Pain Syndrome
Outcomes Mandate National Integration With Cannabis as Medicine
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma
- Trial name
- OMNI-Can (NCT03944447)
- Testing
- Cannabis, Medical, RYAH-Medtech Inhaler
- Where
- 17 sites in United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- OMNI Medical Services, LLC
Cancer, Pediatric Cancer
Yoga in Pediatric Cancer
Pediatric cancer patients and their families experience biopsychosocial difficulties as a result of the long and difficult treatment procedure, which have a severe impact on their quality of life.
- Trial name
- NCT05434871
- Testing
- Yoga training, Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Akdeniz University
Osteoid Osteoma, Benign Bone Tumor
MR-Guided High Intensity Focused Ultrasound for Pain Management Of Osteoid Osteoma & Benign Bone Tumors in Children and Adults
The Philips Sonalleve HIFU system is expected to be efficacious in reducing pain scores in patients with painful osteoid osteoma and other benign bone tumors, and in reducing their pain medication usage.
- Conditions
- Osteoid Osteoma, Benign Bone Tumor, Pain
- Trial name
- NCT02618369
- Testing
- MR-Guided High Intensity Focused Ultrasound
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- The Hospital for Sick Children
Endometriosis of the Cul-de-sac, Chocolate Cyst of Ovary
Peritoneal Cavity Conditioning Decreases Pain, Inflammation and Adhesions
Full conditioning of the peritoneal cavity during laparoscopic surgery will decrease post-operative pain, inflammation and adhesion formation.
- Conditions
- Endometriosis of the Cul-de-sac, Chocolate Cyst of Ovary, Fibroid/Myoma (Uterus/Cervix)
- Trial name
- NCT01344486
- Testing
- full conditioning, standard pneumoperitoneum
- Where
- Belgium
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Pediatric Oncology
Fit to Fight Childhood Cancer
The aim of the study is to investigate the influence of exercise on physical performance and psychosocial aspects in children and adolescents with cancer during and after treatment.
- Trial name
- Kolibri (NCT05867186)
- Testing
- Exercise training
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Johannes Gutenberg University Mainz
Palliative Care
Acupuncture Intervention for AYA With Cancer
The aim of the study is to innovatively extend acupuncture research in adult oncology to adolescents and young adults (AYA) by piloting a tailored acupuncture protocol for pain management in AYA in the Children's Hospital of…
- Trial name
- NCT03516799
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Children's Hospital of Philadelphia
Therapy-Associated Cancer
PainSquad+: A Smartphone App to Support Real-time Pain Management for Adolescents With Cancer
Adolescents with cancer (AWC) are in a unique developmental stage that may mean pain characteristics, the impact of pain, and pain treatment outcomes are different in adolescents compared to children and adults.
- Trial name
- NCT02901834
- Volunteers
- 40 people
- Sponsor
- The Hospital for Sick Children
Leukemia, Hodgkin Lymphoma
Yoga to Alleviate Fatigue, Anxiety and Pain in Adolescents During Treatment for Lymphoma or Leukemia
Researchers at St. Jude Children's Research Hospital want to investigate the feasibility of a yoga intervention for adolescents receiving treatment for lymphoma or leukemia.
- Conditions
- Leukemia, Hodgkin Lymphoma, Lymphoma, Non-Hodgkin's
- Trial name
- NCT02473523
- Testing
- PedsQL Cancer Module, PedsQL Multidimensional Fatigue Scale, Biodex System 3 Dynamometer
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- St. Jude Children's Research Hospital
Anxiety, Pain
Music and VR Effects on Pain, Anxiety, and Fear During Oral Mucositis Care in Leukaemic Children
Children undergoing leukaemia treatment are exposed to a wide range of chemotherapeutic agents and immunosuppressive therapies during treatment and are therefore at great risk for complications.
- Conditions
- Anxiety, Pain, Fear
- Trial name
- NCT06955338
- Testing
- Music intervention, Virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ege University
Prostate Cancer
Prevalence of Neglected Side Effects to Radical Prostatectomy
The purpose of this exploratory data collection is to strengthen our knowledge of some of the rarer distresses following surgical removal of the prostate.
- Trial name
- NCT01742962
- Testing
- Radical prostatectomy for prostate cancer
- Where
- Denmark
- Volunteers
- 396 people
- Sponsor
- Copenhagen University Hospital at Herlev
Therapy-Associated Cancer
The Pain Squad+ Smartphone App To Support Real-Time Pain Management for Adolescents With Cancer
Pain negatively affects the quality of life of adolescents with cancer (AWC). It can also represent a high cost to the healthcare system and families.
- Trial name
- NCT03632343
- Testing
- Pain Squad+ with Nurse Support, Pain Squad+
- Where
- 9 sites in Canada
- Volunteers
- 102 people
- Sponsor
- The Hospital for Sick Children
Anxiety, Pain
Effect of Recreational Play Activities on Anxiety in Children Receiving Chemotherapy and Their Parents
This single-group pretest-posttest study evaluated changes in anxiety levels among children undergoing inpatient chemotherapy and their parents following nurse-led recreational play activities.
- Trial name
- NCT07348900
- Testing
- Nurse-Led Recreational Play Activities
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Akdeniz University
Plasma Cell Myeloma
Evaluating Effectiveness of Powered Drill Bone Marrow Biopsy
Since the introduction of the Jamshidi needle in 1971, new advances in bone marrow sampling have not been seen. In 2007, a new battery-powered bone marrow biopsy system was developed.
- Trial name
- NCT03078452
- Testing
- Power drill, Jamshidi needle
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Emory University
Cancer Pain
Real-life Observational Study of Cancer Pain Management With Methadone
Study rational. Methadone is a distinctive opioid because of its pharmacological characteristics and its multiple modes of action, reinforcing its therapeutic value in managing advanced cancer pain, particularly in cases with a…
- Trial name
- DUNE (NCT05265442)
- Testing
- Methadone
- Where
- France
- Volunteers
- 136 people
- Sponsor
- RECORDATI GROUP