Clinical trials: Pain Intensity Assessment
Patellofemoral Pain Syndrome
A Confirmatory Trial of Multidisciplinary Digital Therapeutics for Patellofemoral Pain Syndrome
This randomized controlled confirmatory study will be evaluating an mobile application, MORA Cure (ETH-01K), owned by EverEx, Inc., to examine safety and effectiveness in individuals with patellofemoral pain syndrome.
- Trial name
- NCT06260865
- Testing
- MORA Cure, Treatment as Usual
- Where
- 10 sites in South Korea
- Volunteers
- 216 people
- Sponsor
- EverEx Inc.
C23.888.592.612.081
Evaluation of an App Based on Artificial Intelligence for Pain Assessment in Pediatric Department
Accurate assessment of pain in Pediatric Department is challenging. However, recent publications highlight that children do not receive optimal pain management, particularly in Emergency Departments.
- Trial name
- DEF II (NCT05527600)
- Testing
- intensity of acute pain evaluation
- Where
- 2 sites in France
- Volunteers
- 2,500 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Pain, Anxiety
Investigation of Pain and Anxiety During Electrodiagnostic Examination Using Self-selected Music
The investigators hypothesized that self-selected music played during electrodiagnosis is effective in relieving the discomfort caused by the procedures.
- Trial name
- NCT01531400
- Testing
- self-selected music
- Where
- Taiwan
- Volunteers
- 61 people
- Sponsor
- Chang Gung Memorial Hospital
Chronic Pain
Clinical Assessment of Pain Processes in Pediatric Patients With Chronic Musculoskeletal Pain
Musculoskeletal (MSK) pain is one of the most common types of pain among children and adolescents. Recurring episodes of MSK pain during childhood does not only impact physical and psychological aspects of daily life but may…
- Trial name
- MSK (NCT04308044)
- Where
- Canada
- Volunteers
- 518 people, healthy volunteers welcome
- Sponsor
- Shriners Hospitals for Children
Postoperative Pain
Evaluation of Postoperative Pain in Children
Postoperative pain is a common symptom of a flare up after root canal treatments (RCTs). Insufficient instrumentation, extrusion of irrigation solutions and debris and existence of a periapical lesion are the factors affecting…
- Trial name
- NCT04510571
- Testing
- Evaluating Postoperative Pain After Root Canal Treatment with Protaper Next, Evaluating Postoperative Pain After Root Canal Treatment with Reciproc Blue Files
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ege University
Physical Functioning, Musculoskeletal Pain
Personalized Exercise Counseling to Promote Workability
The study design is a 2-arm randomized controlled trial with 6-month intervention period and follow-up at 6, 12 and 24 months among blue-color workers of Nokia City with reduced work ability and high number of musculoskeletal…
- Conditions
- Physical Functioning, Musculoskeletal Pain, Quality of Life, Physical Activity
- Trial name
- PEC-Nokia (NCT03854201)
- Testing
- Personalized Exercise Counseling (PEC)
- Where
- Finland
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- UKK Institute
Scoliosis
Sensorial and Physiological Mechanism-based Assessments of Perioperative Pain
The overall goal of this proposal is to determine if quantitative sensory testing (QST) assessing pain modulation can be used as a clinical tool to optimize perioperative pain management.
- Trial name
- RCT (NCT03537612)
- Testing
- Clonidine, Morphine
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Dr. Jean A. Ouellet, MD, FRCSC
Apnea of Prematurity, Retinopathy of Prematurity
Use of Sucrose to Relieve Pain During Eye Exams in Infants
The purpose of this study is to see if an oral sucrose solution can comfort premature infants during their necessary eye exams. The investigators believe that the use of this solution prior to the eye exams will lead to a…
- Conditions
- Apnea of Prematurity, Retinopathy of Prematurity, Pain
- Trial name
- NCT00161694
- Testing
- sucrose solution
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Weill Medical College of Cornell University
Pediatric Dentistry, Local Anesthesia
Pain and Anxiety Evaluation in Children Using Different Techniques of Local Anesthesia for Dental Treatment
Fear and dental anxiety are often associated with the use of needles and syringes for local anesthesia, and painful perception during the administration of local anesthetics is often the main reason for anxiety behaviors and…
- Conditions
- Pediatric Dentistry, Local Anesthesia, Pain Management
- Trial name
- NCT03176446
- Testing
- Local anesthesia with traditional technique, Local anesthesia with computerized technique, Local anesthesia with DentalVibe technique
- Where
- Brazil
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Ponta Grossa
Premature Infant Disease, Retinopathy of Prematurity
Pain of Premature Babies and RetCam (DOLICAM)
It is a single-center prospective observational descriptive study. studied population is premature infants, hospitalized in the neonatology department of the University Hospital of Grenoble and for whom the RetCam examination is…
- Trial name
- DOLICAM (NCT04092127)
- Testing
- Video Record
- Where
- France
- Volunteers
- 31 people
- Sponsor
- University Hospital, Grenoble
Hemophilic Arthropathy
Rofecoxib Efficacy and Safety Evaluation Trial in Hemophilic Arthropathy
This is a multicenter, randomized, double-blind study to evaluate the efficacy and safety of TRM-201 (rofecoxib) versus Placebo in the treatment of patients with hemophilic arthropathy (HA) over a 12-week period (Part I) that is…
- Trial name
- RESET-HA (NCT04684511)
- Testing
- TRM-201 (Rofecoxib)
- Where
- 46 sites in United States, Australia and 6 more
- Volunteers
- 2 people
- Sponsor
- Tremeau Pharmceuticals, Inc.
Pain
Evaluation of Topical Liposomal Lidocaine and Oral Sucrose for Treatment of Pain in Newborns Undergoing Venipuncture
The objective of this study is to determine the relative efficacy of sucrose, liposomal lidocaine, and sucrose plus liposomal lidocaine, on reducing pain during venipuncture in newborn infants.
- Trial name
- NCT00519207
- Testing
- Lidocaine, 24% Sucrose Solution
- Where
- 2 sites in Canada
- Volunteers
- 330 people
- Sponsor
- The Hospital for Sick Children
Pain, Procedural
Pain Assessment in the Perioperative Area
This study is mainly focusing on reducing the pain scores during IV cannulation in pediatric population in the preoperative period. Applying EMLA cream is a well-known fact world wide.
- Trial name
- EMLA (NCT04212208)
- Testing
- IV cannulation
- Where
- India
- Volunteers
- 120 people
- Sponsor
- All India Institute of Medical Sciences, Rishikesh
Femoroacetabular Impingement Syndrome
The Effect of Sacroiliac and Lumbar Mobilizations Applied in Addition to Conventional Physical Therapy
Femoroacetabular impingement (FAI) is defined as impingement caused by abnormal morphology between the femoral head-neck junction and the acetabulum in the hip joint (Aoyama et al., 2017).
- Trial name
- NCT07285876
- Testing
- Lumbosacral Mobilization, Conventional physical therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Fenerbahce University
Pulp Necroses
Post Operative Pain Assessment After Pulpectomy of Primary Molars With Two Different Rotary Systems
Evaluation of post operative pain after pulpectomy procedures for primary molars with irreversible pulp damage and without periapical radulicency using two different systems (One shape file ( ratation movemont) and wave one gold…
- Trial name
- NCT05057325
- Testing
- Pulpectomy using single file system ( One Shape file), Pulpectomy using single file system ( WaveOne Gold file)
- Where
- Egypt
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Minia University
Pain, Burns
Decreasing REcurrent Pain and Anxiety in Medical Procedures With a Pediatric Population: Trial
Children with burn injuries experience severe pain intensity during medical procedures despite the increasing doses of analgesics.
- Conditions
- Pain, Burns, Child, Anxiety
- Trial name
- DREAM-T (NCT02947243)
- Testing
- VR distraction via Oculus Rift, Morphine
- Where
- Canada
- Sponsor
- St. Justine's Hospital
Class II Malocclusion, Division 1
Pain, Discomfort, and Acceptance During Using Electrical Stimulation to Accelerate Orthodontic Teeth Movement
Forty patients with class II division 1 malocclusion who will require extraction of the upper first premolars as a part of the orthodontic treatment plan will be invited to participate in the study.
- Trial name
- NCT05920525
- Testing
- Electrical stimulation, Traditional retraction of the front upper teeth
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Persistent Postoperative Pain
Avoid With Locoregional Analgesia Persistant Postoperative Pain In Children
Persistent postoperative pain is a substantial pain (scores 4-10 using a 0-10 numeric scale) that develops 3 months after surgery. Persistent postoperative pain can be a problem even in ambulatory surgery.
- Trial name
- AWA3PASIC (NCT06271174)
- Testing
- Carbocaine, Profofol and/or Suxaméthonium and/or Sévoflurane
- Where
- France
- Volunteers
- 208 people
- Sponsor
- Nantes University Hospital
Dental Caries in Primary Molars
Clinical Comparison of Cariclast Gel and Rotary Drilling Technique for Caries Removal in 2d Primary Molars
This randomized clinical trial aims to compare two different methods of caries removal in primary molars: the chemomechanical technique using Cariclast gel and the conventional rotary drilling method.
- Trial name
- CARICLAST-RCT (NCT07270458)
- Testing
- cares removal using cariclast gel, Conventional Mechanical Caries Removal
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Pancreatitis, Chronic Pain
Pancreatic Quantitative Sensory Testing (P-QST)
Quantitative Sensory Testing (QST) is a novel investigative technique used in other pain conditions to evaluate patterns of chronic pain, and in this study will be used to elucidate pain patterns in patients with Chronic…
- Conditions
- Chronic Pancreatitis, Chronic Pain, Acute Recurrent Pancreatitis
- Trial name
- NCT06996535
- Testing
- Quantitative Sensory Test 1, Quantitative Sensory Test 2, Quantitative Sensory Test 3
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati