Clinical trials: Pain Measurement
Knee Pain Treated With Knee Arthroplasty
Changes of Plantar Pressure After Knee Reconstructive Surgery
Knee reconstructive surgery (knee prosthesis, osteotomies) often results in changes of alignment of the lower limb axis. This affects also biomechanics of the hindfoot.
- Trial name
- PEDKnee (NCT02906735)
- Testing
- Surgery
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Dyspepsia, Emergency
Symptomatic Relief of Acute Dyspeptic Pain in Emergency Department With Pantoprazole
The purpose of this study is to evaluate the immediate synergistic effect on the relief of severe acid-related dyspeptic pain by adding intravenous pantoprazole to the combination of oral antacid and antispasmodic agent (the…
- Conditions
- Dyspepsia, Emergency, Pain
- Trial name
- NCT01281501
- Testing
- Normal saline, Pantoprazole, Oral antacid
- Where
- Thailand
- Volunteers
- 87 people
- Sponsor
- Chulalongkorn University
Sickle Cell Disease, Chronic Pain
Use of a Mobile-based App for SCD Patients
The study will seek to enroll 100 sickle cell or thalassemia patients who are age 12 or older who have access to a smartphone or tablet with Internet access daily.
- Trial name
- SMART (NCT01833702)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Duke University
Debonding, Orthodontic Brackets
Does the Pain Experienced During Orthodontic Treatment and Bracket Removal Depend on the Architecture of the Bracket?
The present research aimed to thoroughly investigate the impact of bracket architecture on pain perception during active treatment, debonding, and adhesive removal.
- Trial name
- Debonding (NCT06324162)
- Testing
- bracket removal pliers, LODI
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Piotr Fudalej
Pain
Validation of Faces Thermometer Scale (FTS)
The aim of this study is to evaluate validity and reliability of a novel digital pain measure tool, the Faces Thermometer Scale (FTS). Pain is commonly reported by children and adolescents undergoing dental treatment.
- Trial name
- NCT05322018
- Testing
- Faces Thermometer Scale (FTS)
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Malmö University
Dental Pain, Dental Anxiety
Compare the Intensity of Pain Felt by Children During the Local Anesthesia Procedure to That Perceived by the Accompanying Parent.
The goal of this observational study is to compare the intensity of pain experienced by children (aged 6 to 15) during local anaesthesia with that perceived by the parent accompanying them.
- Trial name
- ADDenT (NCT07718477)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Neurofibromatosis Type 1
A Study to Evaluate the Feasibility of a Physiologic Biomarker to Assess Pain and Other Sensory Problems Using Pupillometry in Participants With Neurofibromatosis Type 1 (NF1)
Background: Neurofibromatosis type 1 (NF1) is a genetic condition that causes tumors to grow along the nerves in the skin, brain, and other parts of the body.
- Trial name
- NCT06507748
- Testing
- AlgometRx Nociometer(R)
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- National Cancer Institute (NCI)
Pain
Translation and Cross-Cultural Adaptation Into French of the COMFORTneo Pain Assessment Tool for Newborns
Observational pain assessment scales are essential for the management of pain in young children, particularly in newborns. Numerous observational pain assessment scales for newborns and preterm infants exist worldwide; however…
- Trial name
- TradNeo (NCT07463170)
- Testing
- Expert committee, Pre test
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lung Cancer
Measurement of Pain and Other Symptoms of Non-Small Cell Lung Cancer (NSCLC) Patients Following Thoracic Surgery
Primary Objectives: To longitudinally assess the natural history of symptoms (prevalence, severity, patterns of symptoms, and the relationship of physical and psychological distress) among post-thoracic surgery for non-small cell…
- Trial name
- NCT00501319
- Testing
- Interactive Voice Response (IVR), Questionnaire
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- M.D. Anderson Cancer Center
Sports Injuries, Social Impact
Development Study of Pain Monitoring and Injury Impact Scale
This study introduced and validated the Pain Monitoring and Injury Impact Scale for Athletes (PAMIIS), developed to address the lack of a comprehensive tool in Turkish for assessing injury-related pain and its multidimensional…
- Conditions
- Sports Injuries, Social Impact, Psychological Impact of Injury
- Trial name
- PAMIIS (NCT06955364)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Gazi University
Anesthesia, Local
Pain Assessment During Mandibular Nerve Block Injection With the Aid of Dental Vibe Tool in Pediatric Dental Patients
The purpose of this study is to valuate the effectiveness of DentalVibe(DV) tool in pain reduction during local anesthetic injection compared to traditional injection without aid of DentalVibe in pediatric patients.
- Trial name
- NCT03790540
- Testing
- DentalVibe, Topical Benzocaine 20%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Nourhan M.Aly
Pulp Necroses
Post Operative Pain Assessment After Pulpectomy of Primary Molars With Two Different Rotary Systems
Evaluation of post operative pain after pulpectomy procedures for primary molars with irreversible pulp damage and without periapical radulicency using two different systems (One shape file ( ratation movemont) and wave one gold…
- Trial name
- NCT05057325
- Testing
- Pulpectomy using single file system ( One Shape file), Pulpectomy using single file system ( WaveOne Gold file)
- Where
- Egypt
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Minia University
Breakthrough Pain, Palliative Medicine
Paediatric Breakthrough Pain Assessment
Many children and young people with life-limiting and life-threatening illnesses get sudden bursts of pain called breakthrough pain. At the moment, there aren't any good ways to measure this pain in children and young people.
- Conditions
- Breakthrough Pain, Palliative Medicine, Oncology Pain, Pediatric ALL
- Trial name
- BEACON (NCT06790719)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Newborn Morbidity, Pain
Epidemiology of Painful Procedures in Neonates
Sick or premature neonates are exposed to frequent painful and stressful procedures during their stay in neonatal intensive care units.
- Conditions
- Newborn Morbidity, Pain, Procedures, Intratracheal Intubation
- Trial name
- EPIPPAIN (NCT01346813)
- Where
- 21 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Hôpital Armand Trousseau
Chronic Pain, Cancer
Immersive Multimedia as an Adjunctive Measure for Pain Control in Cancer Patients
This study seeks to explore the efficacy of immersive multimedia experiences as a practical adjunctive therapeutic intervention in the self-management of the chronic pain associated with cancer patients.
- Trial name
- NCT02995434
- Testing
- Virtual Reality Headset, 2D PC
- Where
- 3 sites in Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Elbow Pain, Shoulder Pain
Buckets vs. Braces Prospective Study
The purpose of this research study is to determine if there is a difference in shoulder or elbow pain between youth athletes who throw regularly without a brace, those who use a brace, and those who limit their throw count by…
- Trial name
- NCT06904430
- Testing
- Bucket Group, Brace Group
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Orange County
Pain
NeoFent-I Study; Fentanyl Treatment in Newborn Infants; a Pharmacokinetic, Pharmacodynamic and Pharmacogenetic Study
The study will assess the efficacy of fentanyl using a pharmacokinetic/pharmacodynamic (PK/PD) model where the concentration of the drug is related to effect curve (pain score change in response to standardized procedural pain).
- Trial name
- NCT03897452
- Testing
- Fentanyl (5 microgram/ml) prediluted ampoules
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Lund University
Post Operative Pain
Parent Nurse Controlled Analgesic in Pediatric Patients With Developmental Delay
The purpose of this study is to compare, the safety, efficacy and level of parent and nurse satisfaction with three methods of opioid administration post-operatively in children (4-18 years of age) with developmental delay.
- Trial name
- PNCA (NCT00743730)
- Testing
- Pain and standard side effect management for PNCA with basal method., Pain and standard side effect management with PNCA without basal, Pain and standard side effect management with IV on an as needed basis method.
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Medical College of Wisconsin
Dental Anesthesia
Clinical Evaluation and Comparison of Pain Acceptance of Different Types of Injection Systems
The goal of this randomized clinical trial is to compare two different injection methods in children. The main question it aims to answer is: Is the needle-free injection method more painless than the traditional dental method?…
- Trial name
- NCT06892873
- Testing
- Comfort-In, Traditional dental injection
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Dementia, Pain
PainChek® US Validation Nursing Home Study
Pain is common amongst people living with dementia. However, as people's dementia worsens their ability to self-report pain diminishes because of limitations in their cognition and communication abilities.
- Trial name
- NCT06049732
- Testing
- PainChek®
- Where
- 5 sites in United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- PainChek Ltd