Clinical trials: Pain Thresholds
Tennis Elbow, Health Adult Subjects
Assessment of Pressure Pain Threshold (PPT) and Conditioned Pain Modulation (CPM) After Effect in Patients With and Without Tennis Elbow (TE)
This study at Hashemite University looks at how people with and without tennis elbow (AKA lateral elbow tendinopathy) feel pressure pain and how their bodies briefly "turn down" pain after a cold stimulus.
- Conditions
- Tennis Elbow, Health Adult Subjects, Lateral Elbow Tendinopathy (Tennis Elbow), Pressure Pain Threshold (PPT)
- Trial name
- NCT07178288
- Testing
- Physiological/measurement-validation study
- Where
- Jordan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- The Hashemite University
Migraine
Puberty, Sex Hormones and Pain Sensitivity in Adolescents With Migraine
The purpose of this research study is to investigate the relationships between sex hormone levels and experimental pain sensitivity and migraine severity will be examined.
- Trial name
- IHS (NCT05738213)
- Testing
- Thermal stimuli, Pressure stimuli, Pain ratings
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Transcranial Direct Current Stimulation, Working Memory
Transcranial Direct Current Stimulation Effect on Pain Threshold and Working Memory: Impact of Age and Protocol Type
Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation method which has great potential as an aid in the therapeutic management of neuropsychiatric disorders and chronic pain syndromes.
- Conditions
- Transcranial Direct Current Stimulation, Working Memory, Pain
- Trial name
- NCT04328545
- Testing
- Anodal tDCS on DLPFC, Anodal tDCS on M1
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Pain
Effect of Electroacupuncture on Pain Threshold
This study is designed to evaluate whether or not electroacupuncture can have an effect on the pain threshold of the subject, as compared to sham treatment.
- Trial name
- NCT00802165
- Testing
- Electroacupuncture
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Logan College of Chiropractic
Sickle Cell Anemia
Pressure Pain Tolerance in Relation to Balance and Strength in Children
Sickle cell disease (SCD) is the most frequent life-threatening genetic hemoglobinopathy in the world and occurs due to the synthesis of abnormal hemoglobin S (HbS).Cells with sickle cell hemoglobin are stiff and sticky.
- Trial name
- NCT06529874
- Testing
- Pressure pain tolerance measurement using Digital Pressure Algometer, Balance assessment using HUMAC balance system, Lower limb muscular strength using Lafayette hand held dynamometer
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Adly A Adam
Post-operative Pain, Acute, Pain Threshold
Cold Press Test and Post Operative Pain Relationship
The goal of this clinical trial is to investigate whether it is possible to get a preliminary idea about the postoperative pain in the patient with the results of a practical cold press test applied to American Society of…
- Trial name
- NCT05904873
- Testing
- Mandibular Third Molar Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sinem Büşra Kıraç Can
Sensation Diminished, Pinprick, Pain
Tactile and Pain Sensory Thresholds and Hand Grip Strength
The aim of this study was to compare fingertip tactile sensation, hand and finger grip strength, and hand pain thresholds in children diagnosed with specific learning disorder with impairment in written expression and healthy…
- Conditions
- Sensation Diminished, Pinprick, Pain, Specific Learning Disorder, With Impairment in Written Expression
- Trial name
- NCT07533409
- Testing
- Treatment outcome
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Sultan 1. Murat State Hospital
Cancer
Therapeutic Play on Pain Tolerance and Emotion Regulation in Children
The research is a randomized controlled experimental study. The population of the research will consist of 10-18 year old children who were diagnosed with acute lymphoblastic leukemia and received chemotherapy, who were admitted…
- Trial name
- NCT06368947
- Testing
- Therapeutic Play
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Intellectual Disability
Characterization of Nociception Phenotype in Individuals With Intellectual Disability
Background: People with intellectual disability (ID) often have physical disabilities as well. These physical problems can affect their bones, muscles, nerves, and gastrointestinal tracts. All of these issues can also cause pain.
- Trial name
- NCT05473429
- Testing
- TSA2 Thermosensory Stimulator
- Where
- United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Autism Spectrum Disorder
Participant(s) With Autism and High Pain Tolerance Treated With High Dose Naltrexone
High dose naltrexone with response gauged by pain tolerance as measured by the cold pressor test may help treat autism.
- Trial name
- NCT05100563
- Testing
- 50 mg naltrexone
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Pain
Pain Sensitivity During Puberty
Aim 1- To examine the differences in pain sensitivity between adolescents at early vs. mid pubertal status Aim 2- To determine the relationships between sex hormone levels and pain sensitivity Exploratory Aim 1- To determine the…
- Trial name
- NCT05145595
- Testing
- Thermal Sensory Analyzer, Pressure Stimuli, Mechanical Stimuli
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Healthy, Hyperalgesia
Influence of Genetics in Pain Sensitivity
The purpose of this study is to learn more about the role of genetics in pain sensitivity. Pain perception varies widely among individuals, and information gained from this trial may lead to better methods of preventing and…
- Conditions
- Healthy, Hyperalgesia, Pain
- Trial name
- NCT00001956
- Testing
- Blood draw, Oral surgery, Tissue biopsy
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Childhood Cancer
Pain, Body Composition and Physical Activity in Childhood Cancer.
Comparing baseline assessments of children with cancer and their parents with baseline assessments of healthy children and their parents in a case-control study will allow the investigators to make the comparison in terms of…
- Trial name
- NCT04004455
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel