Clinical trials: Patient-controlled Analgesia
Pain
Assessing the Efficacy of Virtual Reality Analgesia (VRA) in Pediatric Patients for Pain Control
To evaluate the efficacy of virtual reality analgesia (VRA) for pediatric patients undergoing Botulinum toxin injections (BTI) for spasticity management.
- Trial name
- PEDSPAINVR (NCT03480724)
- Testing
- Google Cardboard VRA, Oculus Rift VRA
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Montefiore Medical Center
Analgesia
Erector Spinae Block Versus Caudal Block for Perioperative Analgesia in Pediatric Cancer Patients
The study aim to compare ultrasound guided erector spinae plane block versus ultrasound guided caudal block in perioperative analgesia for pediatric cancer patients
- Trial name
- NCT05153720
- Testing
- Erector spinae plane block, Caudal block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- National Cancer Institute, Egypt
Pancreatitis, Chronic
Surgical Outcome and Differences on Histopathology in Patients With Alcoholic & Non Alcoholic Chronic Pancreatitis
Numerous treatment modalities have been proposed to treat pain in alcoholic and non-alcoholic chronic pancreatitis such as analgesic medication, inhibition of gastric acid production, enzyme substitution, somatostatin analogues…
- Trial name
- NCT02048267
- Testing
- Frey's procedure/Pylorus preserving pancreatoduodenectomy
- Where
- India
- Volunteers
- 24 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Ureteroneocystostomy
The Effect of Intravenous (IV) Patient Controlled Analgesic (PCA) With Ketorolac or Fentanyl Combined With Caudal Block for Postoperative Analgesia in Small Children Undergoing Intravesical Ureteroneocystostomy
The effect of IV PCA with ketorolac or fentanyl combined with caudal block for postoperative analgesia in small children undergoing intravesical ureteroneocystostomy.
- Trial name
- NCT01081535
- Testing
- ketorolac, fentanyl
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Cancer Pediatric
Ultrasound-guided Selective Supraclavicular Nerve Block for Postoperative Pain Control in Pediatric Patients.
This prospective randomized controlled trial aims to investigate the effect of ultrasound-guided selective supraclavicular nerve block on pain control after Hickman catheter, chemoport, or Perm cath insertion in children.
- Trial name
- NCT05015907
- Testing
- Ropivacaine, Control (without intervention)
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Postoperative Pain
Pain Control of Thoracoscopic Major Pulmonary Resection
The purpose of this study is to evaluate whether pre-emptive local bupivacaine injection is a better alternative pain control modality than the conventional intravenous patient controlled analgesia.
- Trial name
- NCT01758809
- Testing
- Pre-emptive bupivacaine wound infiltration, intravenous patient controlled analgesia
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Seoul National University Bundang Hospital
Appendicitis, Pain, Postoperative
Narcotic vs. Non-narcotic Pain Regimens After Pediatric Appendectomy
There is concern that pain prescription after outpatient pediatric surgical procedures is excessive and is in excess of patient need.
- Trial name
- NCT03528343
- Testing
- Non-narcotic pain control
- Where
- United States
- Sponsor
- University of Utah
Postoperative Nausea and Vomiting
Anti Emetic Efficacy of Combination of Ramosetron and Premixture of Naloxone With Patient-controlled Analgesia
Postoperative nausea and vomiting (PONV) is one of the most undesirable complications after general anesthesia, and may lead to increased hospital stay and health care costs.
- Trial name
- NCT02416115
- Testing
- Ramosetron, Naloxone, saline
- Volunteers
- 90 people
- Sponsor
- Kyungpook National University Hospital
Pain Control
Efficacy of TAP Block in Cesarean Section Patients
TAP Block done with 2 different concentrations of bupivacaine and placebo
- Trial name
- NCT03493828
- Testing
- TAP block using Bupivacaine 0.5%, TAP block using Bupivacaine 0.25%, TAP block using Normal Saline
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- New York Presbyterian Brooklyn Methodist Hospital
Sickle Cell Disease
Ibuprofen and Opioid (Morphine or Diamorphine) for Acute Pain in Sickle Cell Disease - Sickle With Ibuprofen & Morphine
The use of oral ibuprofen combined with Opioid (Morphine or Diamorphine) administered through patient controlled analgesia (PCA) will be clinically effective for acute pain crisis in adults with sickle cell disease (SCD).
- Trial name
- SWIM (NCT00880373)
- Testing
- Ibuprofen, Diamorphine or Morphine
- Where
- 2 sites in United Kingdom
- Volunteers
- 320 people
- Sponsor
- London North West Healthcare NHS Trust
Staphylococcus Aureus Bacterial Contamination
Investigation of Antibacterial Effect of Levobupivacaine on Staphylococcus Aureus
This experimental in vitro study aimed to investigate the antibacterial effect of levobupivacaine on Staphylococcus aureus in a patient-controlled analgesia (PCA) model at concentrations commonly used for postoperative pain…
- Trial name
- NCT07285759
- Testing
- Levobupivacaine, Fentanyl, Saline
- Volunteers
- 40 people
- Sponsor
- Dokuz Eylul University
Dental Anxiety, Pain Management
Wand STA vs SleeperOne for Pediatric Local Anesthesia (WASO-Kids)
This randomized, single-blind, split-mouth trial compares the acceptance of two computer-controlled local anaesthetic delivery (CCLAD) systems - Wand® STA and SleeperOne⑤ - in children aged 4-9 years undergoing comparable…
- Trial name
- WASO-Kids (NCT07754851)
- Testing
- Computer-controlled local anesthetic delivery system (pressure-sensing, single-tooth anesthesia type), Computer-controlled local anesthetic delivery system (corded, pen-style electronic type)
- Where
- Greece
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Inguinal Hernia
Comparison of Analgesic Effect of Magnesium Added to Ropivacaine and Ropivacaine Alone in Caudal Analgesia on Postoperative Pain Control in Pediatric Patients Undergoing Inguinal Hernia Repair
A caudal anesthesia is one of the most commonly used technique providing intra and postoperative analgesia in pediatric low abdominal surgery.
- Trial name
- NCT01679353
- Testing
- caudal block, normal saline 0.5ml
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Yonsei University
HSAN Type IV
A Study of Norepinephrine in Patients With Congenital Insensitivity to Pain and Anhidrosis
The aim of this study is to increase norepinephrine levels in a population of young adults where NE levels are very low or undetectable. In order to achieve this, the optimal dose will be determined in a titration step.
- Trial name
- NCT02624310
- Testing
- Droxidopa (L-DOPS)
- Sponsor
- NYU Langone Health
Appendicitis
Cold Therapy for Pediatric Appendectomy
This is a randomized control trial to evaluate the efficacy of an FDA approved cold therapy device vs. usual care among children undergoing appendectomy at a large children's hospital.
- Trial name
- NCT04986397
- Testing
- Cold Therapy, Standard of Care
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Boston Children's Hospital
Agitation
Effects of Serotonin Inhibitors on Patient-controlled Analgesia Related Nausea and Vomiting
ED50 of dexmedetomidine for prevention of emergence agitation after tonsillectomy or adenoidectomy in children
- Trial name
- NCT01517438
- Testing
- agitation
- Volunteers
- 21 people
- Sponsor
- Seoul National University Hospital
Pain, Postoperative, Pediatrics
An Evaluation of Safety of the Fentanyl Transdermal System for Management of Acute Post-Operative Pain in Pediatric Patients
The purpose of this study is to evaluate the safety and clinical utility of fentanyl HCl 40 mcg system for the management of postoperative pain in pediatric inpatients.
- Trial name
- NCT00666393
- Testing
- fentanyl iontophoretic transdermal system (40mcg)
- Sponsor
- Alza Corporation, DE, USA
Postoperative Pain, Opioid Use
SZMN Blocks for Pain Control in Pediatric Patients Undergoing T&A
The suprazygomatic maxillary nerve (SZMN) block is a well-established, safe and effective regional technique for pain management following cleft palate procedures, however, have not been studied for patients undergoing…
- Trial name
- SZMN (NCT04797559)
- Testing
- SZMN Block
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stanford University
Anesthesia, Local, Postoperative Pain
Comparison of Supraclavicular and Costoclavicular Brachial Plexus Blocks in Pediatrics
In upper extremity surgeries, the brachial plexus block can be performed with different techniques at various levels depending on the proximal and distal level of the surgery.
- Trial name
- NCT04782778
- Testing
- Bupivacaine 0.25% Injectable Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Congenital Heart Disease in Children
Continuous vs Intermittent Ketorolac for Pain Control in Peds CV Surgery
The proposed study will be a prospective, randomized, double blind, placebo controlled trial to compare the use of a continuous infusion versus intermittent ketorolac on postoperative patients in the pediatric cardiovascular ICU.
- Trial name
- CIVIK (NCT04040452)
- Testing
- Continuous ketorolac
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- Phoenix Children's Hospital