Clinical trials: Patient-controlled Analgesia
Laparoscopic Surgery, Visceral Pain, Postoperative
Anrikefon-based Patient-controlled Intravenous Analgesia Following Laparoscopic Surgery
Visceral pain following laparoscopic surgery is frequently underestimated, yet it is associated with a range of adverse outcomes.
- Conditions
- Laparoscopic Surgery, Visceral Pain, Postoperative, Anrikefon, Patient-controlled Intravenous Analgesia
- Trial name
- NCT07525986
- Testing
- High-dose anrikefon, Medium-dose anrikefon, Low-dose anrikefon
- Where
- 4 sites in China
- Volunteers
- 140 people
- Sponsor
- Peking University First Hospital
Scoliosis; Adolescence, Pain After Surgery
Tegileridine for Postoperative Pain After Adolescent Scoliosis Surgery
The goal of this clinical trial is to see if a new pain medicine called Tegileridine is at least as effective as morphine (the standard treatment) for pain relief after spinal surgery in teenagers with scoliosis.
- Conditions
- Scoliosis; Adolescence, Pain After Surgery, Analgesia, Patient-controlled
- Trial name
- NCT07229495
- Testing
- Tegileridine, morphine
- Where
- 6 sites in China
- Volunteers
- 171 people
- Sponsor
- Peking Union Medical College Hospital
Postoperative Pain After Thoracic Surgery, Postoperative Pain
Comparison of IV Analgesia Protocols After the Regional Block's Effect Diminishes in Thoracic Surgery
The purpose of this study is to compare the effectiveness of three different intravenous (IV) patient-controlled analgesia (PCA) regimens-Fentanyl, Tramadol, and Ibuprofen-in managing postoperative pain and respiratory…
- Conditions
- Postoperative Pain After Thoracic Surgery, Postoperative Pain, Thoracic Surgery, Video Assisted, Patient Controlled Analgesia
- Trial name
- NCT07610408
- Testing
- Fentanyl IV PCA, Tramadol IV PCA, Ibuprofen IV PCA
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Ankara Etlik City Hospital
Patient-Controlled Analgesia
Nausea and Vomiting in Postoperative Paediatric Patients With Patient-Controlled Analgesia (PCA): Morphine vs Oxycodone
POPCORN trial will compare the side effects and effectiveness of Morphine versus Oxycodone medication when prescribed for use as patient controlled analgesia (PCA) for pain relief for paediatric patients after-surgery.
- Trial name
- POPCORN (NCT06186141)
- Testing
- Morphine, Oxycodone
- Where
- Australia
- Volunteers
- 690 people
- Sponsor
- Murdoch Childrens Research Institute
Postoperative Pain, Laparoscopic Cholecystectomy
External Oblique Intercostal Block (EOICB) for Laparoscopic Cholecystectomy
This single-center, prospective, randomized controlled trial aims to compare the effects of paravertebral block (PVB), external oblique intercostal (EOI) block, and intravenous patient-controlled analgesia (PCA) with tramadol on…
- Conditions
- Postoperative Pain, Laparoscopic Cholecystectomy, Paravertebral Block, External Oblique Intercostal Plane Block
- Trial name
- NCT07241949
- Testing
- Paravertebral Block (PVB), External Oblique Intercostal Block (EOI Block), Tramadol IV Patient-Controlled Analgesia (PCA)
- Where
- Turkey (Türkiye)
- Volunteers
- 147 people
- Sponsor
- Cukurova University
Surgery, Pain Management
Comparison of Cumulative Opioid Consumption Between Variable-Rate Feedback Infusion and Fixed-Rate Basal Infusion Modes of Intravenous PCA Following Mixed Surgery
Perioperative pain management affects patient recovery. However, the rate of moderate to severe postoperative pain is as high as 73.8%, which hinders recovery and increases the risk of complications.
- Conditions
- Surgery, Pain Management, Opioid Consumption, Patient-controlled Analgesia
- Trial name
- NCT07361822
- Testing
- Fixed-rate basal infusion mode, Variable-rate feedback infusion mode
- Where
- China
- Volunteers
- 1,170 people
- Sponsor
- Beijing Tiantan Hospital
Laparoscopic Surgery, Visceral Pain, Postoperative
Anrikefon-based Patient-controlled Intravenous Analgesia After Laparoscopic Surgery
Visceral pain following laparoscopic surgery is frequently underestimated, yet it is associated with a range of adverse outcomes.
- Conditions
- Laparoscopic Surgery, Visceral Pain, Postoperative, Anrikefon, Patient-controlled Intravenous Analgesia
- Trial name
- NCT07246785
- Testing
- High-dose anrikefon, Medium-dose anrikefon, Low-dose anrikefon
- Where
- China
- Volunteers
- 13 people
- Sponsor
- Peking University First Hospital
Surgery, Pain Management
Comparison of the Efficacy and Safety of Fixed-rate Basal Infusion Mode and Time-programmed Decremental Background Infusion Mode of Intravenous PCA Following Mixed Surgery
Perioperative pain management affects patient recovery. However, the rate of moderate to severe postoperative pain is as high as 73.8%, which hinders recovery and increases the risk of complications.
- Conditions
- Surgery, Pain Management, Opioid Consumption, Patient Controlled Analgesia
- Trial name
- NCT07375121
- Testing
- Fixed-rate basal infusion mode, Time-programmed decremental background infusion mode
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Beijing Tiantan Hospital
Elderly, Hip Fracture Surgery
Dexmedetomidine Supplemented Analgesia and Delirium After Hip Fracture Surgery
Delirium is common in the elderly after hip fracture surgery, and is associated with worse outcomes. The investigators hypothesize that, for elderly patients after hip fracture surgery, dexmedetomidine supplemented analgesia can…
- Conditions
- Elderly, Hip Fracture Surgery, Patient-controlled Analgesia, Dexmedetomidine
- Trial name
- NCT04955249
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 67 people
- Sponsor
- Peking University First Hospital
Anesthesia, Analgesia
Intrathecal Morphine vs. Quadratus Lumborum Block for Pain in Laparoscopic Nephrectomy
In this study, it was aimed to evaluate the effects of subcostal anterior quadratus lumborum block (S-QLB3) and İntrathecal morphine (ITM) on postoperative acute pain scores and opioid consumption in the first 24 hours after…
- Conditions
- Anesthesia, Analgesia, Acute Pain, Patient Controlled Analgesia
- Trial name
- NCT06630858
- Testing
- Subcostal Anterior Quadratus Lumborum Block, Intrathecal Morphine, Patient Controlled Analgesia (IV PCA)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ondokuz Mayıs University
Postoperative Pain, Patient Controlled Analgesia
Monitoring Postoperative Patient-controlled Analgesia (PCA)
The introduction of Acute Pain Service (APS), 1985, specialized pain management could be offered to the inpatient care. An example of this is patient-controlled analgesia (PCA), which is a technique that is used mostly after…
- Conditions
- Postoperative Pain, Patient Controlled Analgesia, Surgery, Nurse-Patient Relations
- Trial name
- NCT03697278
- Testing
- Smith medical CADDsolis
- Where
- 2 sites in Sweden
- Volunteers
- 90 people
- Sponsor
- Pether Jildenstal
Esophageal Cancer, Perioperative Analgesia
Perioperative Analgesia Modes in Minimally Invasive Esophagectomy
This study was designed to compare analgesic efficacy and safety of different perioperative analgesic modes in minimally invasive esophagectomy for esophageal cancer.
- Conditions
- Esophageal Cancer, Perioperative Analgesia, NSAIDs, Opioid
- Trial name
- NCT05504265
- Testing
- Preemptive flurbiprofen axetil, Postoperative flurbiprofen axetil, Patient-controlled analgesia pump
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Analgesia, Patient-Controlled, Dexmedetomidine
Two-channel IV-PCA With Dexmedetomidine
Dexmedetomidine was administered in the 'selector' channel and fentanyl in the 'basic \& bolus' channel of dual channel intravenous patient-controlled analgesia (IV-PCA) and the amount of opioid consumption was compared.
- Trial name
- NCT05672225
- Testing
- Dexmedetomidine, Control
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Korea University Guro Hospital
Idiopathic Scoliosis, Erector Spinae Plane Block
Erector Spinae Plane Block v.s Patient Controlled Analgesia in Correction Surgery for Idiopathic Scoliosis
Scoliosis correction surgery involves extensive surgical wounds, intense intraoperative stimulation, and severe postoperative pain, often necessitating the use of potent opioids.
- Conditions
- Idiopathic Scoliosis, Erector Spinae Plane Block, Patient Controlled Analgesia
- Trial name
- NCT06728046
- Testing
- ESPB, PCA
- Where
- China
- Volunteers
- 40 people
- Sponsor
- West China Hospital
Analgesia, Patient-Controlled
Oxycodone and Sufentanil for Analgesia in Hip Surgery
We design this randomized controlled trial to compare the safety and efficacy of Oxycodone and Sufentanil for postoperative patient-controlled analgesia in patients undergoing hip surgery, with a view to finding the optimal…
- Trial name
- NCT03685188
- Testing
- Oxycodone Hydrochloride, Sufentanil Citrate
- Where
- China
- Volunteers
- 570 people
- Sponsor
- West China Hospital
Quality of Recovery, Elective Cesarean Section
Evaluating The Quality of Recovery After Elective Cesarean Section
Adequately validated patient-reported outcome measures are available, which can assess recovery profiles following childbirth. This study will explore the effect of two different methods for pain management on the quality of…
- Conditions
- Quality of Recovery, Elective Cesarean Section, Quadratus Lumborum Block, Patient Controlled Analgesia
- Trial name
- NCT06155968
- Testing
- QL block, PCA
- Where
- Egypt
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Analgesia, Patient-Controlled, Postoperative Pain, Acute
Comparison of Two Different Approach TAP Block on Pain Management of Laparoscopic Nephrectomy
Primary aim is to compare the effectiveness of the posterior approach Transversus abdominis plane block (P-TAP) and the lateral approach Transversus abdominis plane block (L-TAP) technique on the pain management of the…
- Trial name
- NCT05188794
- Testing
- lateral tap block, posterior tap block
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Ankara City Hospital Bilkent
Pain, Postoperative, Lumbar Spine Degeneration
Epidural PCA on Pain Relief After L-spine Surgery
This study aimed to evaluate the effect of epidural patient-controlled analgesia (PCA) on postoperative pain relief after lumbar spine surgeries.
- Conditions
- Pain, Postoperative, Lumbar Spine Degeneration, Analgesia, Patient-Controlled, Epidural Anesthesia
- Trial name
- NCT06316921
- Testing
- Epidural patient-controlled analgesia, Standard postoperative pain management
- Where
- Taiwan
- Volunteers
- 209 people
- Sponsor
- Taipei City Hospital
Epidural Analgesia, Patient Controlled Analgesia
The Effectiveness and Outcomes of Epidural Analgesia in Patients Undergoing Open Hepatectomy
This observational study is to compare the effectiveness and outcomes of epidural analgesia in patients undergoing open hepatectomy: A propensity score matching analysis.
- Trial name
- NCT06301932
- Testing
- Open liver resection
- Volunteers
- 654 people
- Sponsor
- Chiang Mai University
Anesthesia, Analgesia
Anterior Quadratus Lumborum Block Versus Erector Spina Plane Block in Percutaneous Nephrolithotomy Surgery
In this study, it was aimed to evaluate the effects of anterior quadratus lumborum block (QLB3) and Erector Spina Plane Block (ESPB) on postoperative acute pain scores and opioid consumption in the first 24 hours in Percutaneous…
- Conditions
- Anesthesia, Analgesia, Patient Controlled Analgesia, Quadratus Lumborum Block
- Trial name
- NCT05822492
- Testing
- Group QLB3, Group ESPB, Group Control
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ondokuz Mayıs University