Clinical trials: Patients Outcomes
Tracheostomy Patients, Multidisciplinary Care Team
Evaluation of a Specialised Tracheostomy Team for the Management of Patients With a Tracheostomy Cannula in a Belgium General Hospital: A Retrospective Study.
Patients admitted to intensive care units (ICUs) frequently require prolonged mechanical ventilation. Difficulties in weaning from mechanical ventilation represent an important indication for performing a tracheotomy, which…
- Conditions
- Tracheostomy Patients, Multidisciplinary Care Team, Outcomes, Hospital
- Trial name
- NCT07755969
- Testing
- The implementation of the specialised multidisciplinary tracheostomy team.
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Vitaz
an Intelligent Teaching Agent for the "Epidemiology" Course of the MBBS Program, Students' Critical Thinking, Practical Ability and Learning Outcomes
Research and Application of an AI Agent-Based MBBS Course Assistant
Prior to the quasi-experiment, this study performed semi-structured interviews among Bachelor of Medicine and Bachelor of Surgery(MBBS) undergraduate students from the Belt and Road International Medical College, Zhejiang…
- Trial name
- NCT07752160
- Testing
- Socratic Agent for Guided Epidemiology, General LLM
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Malocclusion, Angle Class II, Overbite (Excessive) Horizontal
Long-term Stability of Treatment With the Twin Block Appliance
The objective of this observational study is to investigate the long-term stability of treatment with the Twin block appliance in a patient group previously treated with a Twin block appliance.
- Conditions
- Malocclusion, Angle Class II, Overbite (Excessive) Horizontal, Overbite (Excessive) Deep, Treatment Outcome
- Trial name
- NCT07752498
- Where
- Sweden
- Volunteers
- 72 people
- Sponsor
- Region Jönköping County
Preeclampsia Postpartum, Adverse Pregnancy Outcomes
A Community Health Worker Intervention to Address Adverse Pregnancy Outcomes
United States maternal mortality and preterm birth rates are among the highest among high-income countries due in part to a combination of racial, regional and socioeconomic disparities in access to care and overall health.
- Trial name
- AW2H (NCT06353256)
- Testing
- usual postpartum care, usual postpartum care + community health worker intervention
- Where
- 2 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Quality of Life Outcomes
Palliative Care Integration in Pediatric Oncology Phase 1 Clinical Trials
Although cure rates continue to rise, one in five children with cancer still die from their disease, so new therapies are urgently needed.
- Trial name
- NCT07696065
- Testing
- Pediatric Palliative Care Consultation
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Phoenix Children's Hospital
ECMO Outcomes, Respiratory Failure (Pediatric Patients)
ECMO Use in Pediatric Oncology and HSCT Patients: A Descriptive and Comparative Analysis
This was an observational study, with a descriptive and comparative portion. The descriptive analysis, a large single center experience, examined bleeding complications, infectious rates, and survival outcomes in patients under…
- Conditions
- ECMO Outcomes, Respiratory Failure (Pediatric Patients), Malignancies, Hematologic, Solid Tumor Malignancies
- Trial name
- NCT07712835
- Testing
- Extracorporeal membrane oxygenation (ECMO)
- Volunteers
- 22 people
- Sponsor
- Children's Mercy Hospital Kansas City
Sexually Transmitted Infection, HIV/AIDS
Clinical Study of STI Screening to Prevent Adverse Birth and New-born Outcomes (Philani Ndiphile)
This study aims to evaluate different screening strategies to decrease the burden of Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT) and Trichomonas vaginalis (TV) among pregnant women, and reduce adverse birth outcomes.
- Conditions
- Sexually Transmitted Infection, HIV/AIDS, Cost-effectiveness, Birth Outcomes
- Trial name
- NCT04446611
- Testing
- First antenatal care + test-of-cure, First antenatal care + week 30-34 gestation (no test-of-cure)
- Where
- South Africa
- Volunteers
- 2,247 people, healthy volunteers welcome
- Sponsor
- Foundation for Professional Development (Pty) Ltd
Pregnancy Complication, Aortic Dissection
PregnAncy-Related Aortic DISsEction in China
A multicenter observational study on pregnancy-related aortic dissection
- Conditions
- Pregnancy Complication, Aortic Dissection, Marfan Syndrome, Loeys-Dietz Syndrome
- Trial name
- PARADISE (NCT07672210)
- Testing
- Intervention strategies including medication or surgery
- Where
- 4 sites in China
- Volunteers
- 500 people
- Sponsor
- DeltaHealth Hospital · Shanghai
Pediatrics, Neurological Abnormality
Turkish Version of the BRIEF-Hammersmith Infant Neurological Examination (HINE)
The American Academy of Pediatrics defines infants at risk as those with preterm birth, special health care needs, family risk factors, and those at risk of early death.
- Conditions
- Pediatrics, Neurological Abnormality, Neurodevelopment Outcome
- Trial name
- BRIEF-HINE (NCT07182474)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Body Image, Mental Health Outcomes
Overvaluation of Weight and Shape Intervention vs The Body Project
Priorities aims to reduce body image concerns, prevent eating disorders, bolster self-esteem, and promote mental and emotional health by helping participants identify and nurture alternative sources of self-worth.
- Conditions
- Body Image, Mental Health Outcomes, Eating Disorders, Body Dysmorphic Disorders
- Trial name
- NCT07678554
- Testing
- Priorities, Body Project
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Stanford University
Maternal Health Services, Outcome Assessment
Long Term Effects Of a Maternal Cash Transfer Experiment
This is a follow-on study to a cluster randomized trial of maternal conditional incentives conducted in Nigeria. This study found that cash transfers, conditional on women obtaining facility-based prenatal, delivery, and…
- Trial name
- NCT05709457
- Testing
- Cash transfer in prior study
- Where
- Nigeria
- Volunteers
- 18,131 people, healthy volunteers welcome
- Sponsor
- RAND
Adult Hospital Patients at Risk of Adverse Outcomes
Portsmouth CORE-D Routine Care Data Repository
An integrated database of depersonalised routine hospital patient data consisting of demographic and disease attributes, physiological or laboratory measurements, care contacts and interventions along with associated clinical…
- Trial name
- CORE-D (NCT04983082)
- Where
- United Kingdom
- Volunteers
- 750,000 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Neonatal Hyperbilirubinemia, Treatment Decisions
Bilirubin Thresholds in Preterm Infants on Neonatal Intensive CarE Units: The B-NICE Trial
Rationale: Neonatal hyperbilirubinemia is highly prevalent in very preterm infants born <30 weeks. Since 2008, uniform Dutch phototherapy thresholds for preterm infants have been used nationwide, largely based on consensus.
- Conditions
- Neonatal Hyperbilirubinemia, Treatment Decisions, Neurodevelopmental Outcome, Phototherapy
- Trial name
- B-NICE (NCT07674537)
- Testing
- Phototherapy, Exchange Transfusion
- Where
- Netherlands
- Volunteers
- 680 people
- Sponsor
- University Medical Center Groningen
Neonatal Outcomes, Pregnancy Complications, Infectious
Systematic Screening of Lower Genital Tract Infections
Introduction: The investigation of systematic screening for asymptomatic genital infections in pregnant women is justified by the relevance of these conditions in determining adverse neonatal outcomes, such as prematurity, low…
- Conditions
- Neonatal Outcomes, Pregnancy Complications, Infectious, Premature Birth, Premature Rupture of Fetal Membranes
- Trial name
- NCT07592286
- Testing
- Enhanced microbiological screening, Standard prenatal care
- Volunteers
- 250 people
- Sponsor
- Universidade Federal do Pampa
Husband Attendance, Maternal-Neonatal Outcomes
Effect of Husband Attendance on Anesthesia Performance and Maternal-Neonatal Outcomes During Elective Cesarean Section Under Spinal Anesthesia
Family-centered perinatal care has become an integral component of modern obstetric practice, emphasizing emotional support and shared parental experiences during childbirth.
- Trial name
- NCT07641751
- Testing
- Husbands will be allowed to attend the cesarean section procedure, providing emotional support to their partners., Husbands will not be permitted to attend the cesarean section procedure
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Multiple Myeloma, Patient Reported Outcome (PRO)
Digital Support for Multiple Myeloma Quality of Life
The objective of this prospective study is to investigate the quality of life of patients with multiple myeloma and the effectiveness of support provided through a personalized web-based platform.
- Conditions
- Multiple Myeloma, Patient Reported Outcome (PRO), Supportive Care in Cancer, Quality of Life
- Trial name
- DigiMyQoL (NCT07642362)
- Testing
- Digital support
- Where
- Greece
- Volunteers
- 108 people
- Sponsor
- CareAcross
Thyroid Function, Preterm
Thyroxine Supplementation in Small for Gestational Age (SGA) Infants With Birth Weight <1500g and TSH 6-20 mIU/ml
The primary objective of this clinical trail is to evaluate whether early supplementation of levothyroxine (L-T4) at a dosage of 8 ug/kg/d, initiated in the second week of life, improves physical growth and neurodevelopmental…
- Conditions
- Thyroid Function, Preterm, SGA and Growth, Neurodevelopment Outcome
- Trial name
- NCT07625722
- Testing
- Levothyroxine Sodium (LT4) Tablets
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Shandong Provincial Hospital
Ovarian Aging, Adverse Pregnancy Outcomes
The Bone and hEArt Health Consequences of Ovarian agiNg (BEACON) Study
Ovarian aging is a major driver of a woman's long-term health and disease risk. In particular, the rapid decline in the ovarian reserve that occurs with the menopause transition is linked to a striking increase in the risk for…
- Trial name
- BEACON (NCT07621965)
- Volunteers
- 655 people
- Sponsor
- Indiana University
Infant Neurodevelopment, Nutrition
Maternal Methyl-Nutrient Status and Infant Neurodevelopment Study
This prospective cohort study examines the relationship between maternal methyl-nutrient status during pregnancy and offspring neurodevelopment.
- Conditions
- Infant Neurodevelopment, Nutrition, Methylation, Birth Outcomes
- Trial name
- NCT07568561
- Where
- 2 sites in Taiwan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Prematurity Complications, Neurodevelopment Outcome
Antenatal vs Postnatal Transport Team Positioning in Extremely Preterm Outborn Infants
The extremely preterm outborn births (delivered in maternity units without on-site neonatal intensive care) are associated with lower survival and increased risk of severe neurodevelopmental impairment compared with inborn births…
- Conditions
- Prematurity Complications, Neurodevelopment Outcome, Prematurity
- Trial name
- OutbornTRANSF (NCT07580859)
- Testing
- Usual Care
- Where
- France
- Volunteers
- 627 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris