Clinical trials: Pectus Deformity
Pectus Excavatum, Cardiac Anomaly
Capturing Physiologic Autonomic Data from Clinically Indicated Magnetic Resonance Imaging Scans in Children
The Fontan Procedure is a palliative surgical procedure used in pediatric patients with one functional ventricle. The procedure, a series of stepwise operations that alter cardiorespiratory physiology, separate the systemic and…
- Trial name
- CMRI (NCT06110689)
- Testing
- VU-AMS device
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pectus Excavatum
Cryoanalgesia for Pain Management After Pectus Excavatum Repair
Cryoanalgesia for pain management after pectus excavatum repair. COPPER study (CryoanalgesiafOr Pain management after Pectus Excavatum Repair): a randomized controlled trial.
- Trial name
- COPPER (NCT05201820)
- Testing
- Cryoanalgesia
- Where
- Italy
- Volunteers
- 88 people
- Sponsor
- Istituto Giannina Gaslini
Pectus Excavatum
Quantifying Changes in the Thoracic Wall After Nuss Bar Removal in Pectus Excavatum Patients Using 3D Imaging
Pectus excavatum (funnel chest) is the most common congenital anterior thoracic wall deformity. It can be associated not only with cosmetic concerns but also with psychosocial and limiting somatic complaints.
- Trial name
- CHEST (NCT07498699)
- Where
- Netherlands
- Volunteers
- 69 people
- Sponsor
- Erik de Loos
Cryotherapy Effect, Pectus Excavatum
Percutaneous Intercostal Cryoneuromodulation Onset Timing.
Percutaneous Intercostal Cryoneurolysis is a promising technique that addresses acute postoperative pain after Nuss procedure for pectus excavatum. However its onset timing has not yet been determined.
- Trial name
- NCT07081620
- Testing
- Physical examination of chest skin
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Papa Giovanni XXIII Hospital
Pectus Excavatum
The Effect of Patient Position on the External Haller Index Value Among Patients With Pectus Excavatum
Pectus excavatum is the most common anterior chest wall deformity, affecting up to 1:400 of newborns. The current gold standard to quantify the extent of deformity is by calculating the Haller Index based on a Computed Tomography…
- Trial name
- POSITION (NCT04046835)
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
Pain, Postoperative, Excavatum, Pectus
Comprehensive Study of Post-surgical Pain After Pectus or Spine Surgery
This will be a prospective observational study to determine the association between specific genotypes, epigenetics, behavioral, social and biological factors, with the phenotypes, defined by pain perception, postoperative pain…
- Conditions
- Pain, Postoperative, Excavatum, Pectus, Scoliosis Idiopathic
- Trial name
- NCT04031716
- Testing
- Meditation
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pectus Excavatum
Three-dimensional Optical Surface Imaging as a Diagnostic Tool in Pectus Excavatum
Pectus excavatum (PE) is the most common anterior chest wall deformity. Currently, a chest radiography (CR) or Computed Tomography (CT) scan is acquired to determine and objectify pectus severity using the Haller Index.
- Trial name
- 3D PECTUS (NCT03926078)
- Testing
- 3D optical surface image, Chest radiography, CT scan
- Where
- Netherlands
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
Pectus Excavatum, Pectus Deformity
Assessing Virtual Reality for Perioperative Anxiolysis in Adolescents Undergoing MIRPE Surgery
In this randomized control trial, investigators would like to assess as primary objective the effectiveness of VR in anxiolysis via using State Trait Anxiety- Inventory test various time during the perioperative period with…
- Trial name
- NCT06446518
- Testing
- Virtual reality exposure
- Where
- Hungary
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Funnel Chest
Evaluation of Chest Wall Motility After MIRPE
Pectus excavatum (PE) is the most common congenital deformity of the chest wall and surgical treatment using the minimally invasive technique (MIRPE) is consolidating as the choice to perform PE correction.
- Trial name
- NCT05124626
- Testing
- MIRPE with two bars, MIRPE with one bar
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Pain, Postoperative
Short and Long-term Effects of Surgical Repair of Pectus Deformities
A large number of institutions have reported their early results with minimally invasive repair of pectus excavatum and open repair of pectus carinatum, but only few have addressed the outcomes relevant to the concerns of the…
- Trial name
- NCT01329120
- Testing
- Minimally invasive repair of pectus excavatum, Open surgical repair of pectus carinatum
- Where
- Denmark
- Volunteers
- 1,000 people
- Sponsor
- University of Aarhus
Scoliosis Idiopathic Adolescent, Chest Deformities
Sagittal Spine Balance in Patients With Chest Wall Deformity
Does the funnel deformity affects the sagittal balance of the spine? This question is a result of a Principal Investigator's novel observation, that in some cases restoring the correct balance reduce the distance between the…
- Trial name
- NCT07070609
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Pomeranian Medical University Szczecin
Pectus Excavatum, Chest Deformities
SPSIPB Versus SAPB for Postoperative Analgesia After Minimally Invasive Repair of Pectus Excavatum
This prospective observational cohort study will compare postoperative analgesic outcomes in patients undergoing minimally invasive repair of pectus excavatum.
- Trial name
- NCT07697222
- Testing
- Postoperative Analgesia Protocol, Bispectral Index Monitoring, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Marmara University
Funnel Chest, Excavatum, Pectus
Cryoanalgesia Aplication Time Optimization During Nuss Procedure
This study compared standard therapy (multimodal analgesia with 2 minutes cryoanalgesia) versus a novel approach (multimodal analgesia with 1 minute cryoanalgesia) in subject undergoing minimal invasive modyfied Nuss procedure…
- Trial name
- NCT05831137
- Testing
- shorter cryoanalgesia
- Where
- Poland
- Volunteers
- 20 people
- Sponsor
- Pomeranian Medical University Szczecin
Pectus Excavatum
ES Catheter vs Cryoablation After Pectus Surgery
Participants will be randomized to receive ES catheter or cryoablation for pain management after the Nuss procedure. The goal of this study is to compare the following between the two groups: Time to achieve short-term physical…
- Trial name
- NCT06682208
- Testing
- ES catheter, Intercostal nerve cryoablation (INC)
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pectus Excavatum, Pectus Carinatum
Psychological Assessment of Patients With Chest Wall Deformities
The study aims to investigate the most frequent psychological outcomes associated to chest wall deformities and patients' quality of life.
- Trial name
- NCT04362878
- Where
- Italy
- Volunteers
- 209 people
- Sponsor
- University of Florence
Postoperative Pain
Prediction of Acute Postoperative Pain and Analgesic Consumption
Pain is an expected part of surgical recovery but effective pain management remains challenging. The high variability in postoperative pain experience and analgesic treatment response between patients is part of the challenge.
- Trial name
- MIRPEX-3 (NCT02230865)
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Kasper Grosen
Pectus Excavatum, Funnel Chest
Cryoanalgesia vs. Epidural in the Nuss Procedure
The purpose of this study is to determine whether cryoanalgesia provides better pain control for minimally invasive pectus excavatum repair (the Nuss procedure) than thoracic epidural.
- Trial name
- NCT02721017
- Testing
- Cryoanalgesia, Thoracic epidural (ropivicaine, fentanyl)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Pectus Excavatum
The Effect of Surgical Repair of Chest on Postural Stability Among Patients With Pectus Excavatum
The goal of this study is to determine the effect of Nuss minimally-invasive repair technique of pectus excavatum (PE) on the postural stability in patients with PE.
- Trial name
- NCT05844800
- Testing
- Nuss repair of Pectus Excavatum, Epidural anesthesia
- Where
- 2 sites in Poland
- Volunteers
- 43 people
- Sponsor
- Poznan University of Physical Education
Pectus Excavatum
Nuss Procedure: Clinical Options in Pediatric Pain Management?
A retrospective chart review study analyzing the benefits of patient controlled analgesia, thoracic epidural analgesia, and paravertebral nerve block catheters in patients having surgical repair of pectus excavatum using the Nuss…
- Trial name
- NCT02009267
- Testing
- Patient controlled analgesia, Continuous thoracic epidural infusions, Continuous paravertebral blockade
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Ralph Beltran
Pectus Excavatum, Funnel Chest
Effectiveness of One-Minute Versus Two-Minute Cryoanalgesia in Nuss Surgery
Intercostal nerve cryoanalgesia has become a popular method for managing postoperative pain after Nuss procedure, showing greater effectiveness compared to epidural anesthesia and patient-controlled analgesia.
- Trial name
- Cryo-One (NCT06935799)
- Testing
- One minute intercostal nerves cryoanalgesia, Two minutes intercostal nerves cryoanalgesia
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Children's Memorial Health Institute, Poland