Clinical trials: Pediatric Sedation
Procedural Anxiety, Emergencies
Comparing in Dexmedetomidine With po/pr Midazolam for Procedural Sedation in the Pediatric Emergency Department
This study aims to compare efficacy of Procedural Sedation with Dexmedetomidine as compared to Midazolam in the pediatric Emergency Department.
- Trial name
- PedINDEX (NCT03399838)
- Testing
- Dexmedetomidine, Midazolam
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Neurological Disorders
Comparison of the Effectiveness of CAM Therapies in Pediatric Patients Undergoing Sedation
The investigators conducted a prospective open unblinded clinical four-arm evaluation of Complementary and Alternate Medicine (CAM) interventions on children 1-12 years of age who were undergoing imaging by Medical Resonance…
- Trial name
- NCT01858350
- Testing
- Active Music Therapy, Passive Music Therapy, Distraction Therapy
- Where
- United States
- Volunteers
- 471 people
- Sponsor
- Wayne State University
Sedation
Safe Administration of Propofol for Sedation in Children
Advances in health care require that more children are given sedation to allow doctors to perform investigations or minor procedures. Sedation drugs have traditionally been given orally (swallowed) by children.
- Trial name
- NCT00832013
- Testing
- Propofol
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Procedural Sedation and Analgesia, Pediatric ALL
Study of the Efficacy of Moderate Sedation With Intra-NAsal Dexmedetomidine Monitored by EEG MOnitoring
This is a prospective, monocentric diagnostic study aiming to evaluate whether a sedation score obtained by a per-procedural electroencephalogram (EEG), the PSI score, could identify patients for whom a 2 μg/kg dose of DEX would…
- Trial name
- DINAMO (NCT06867289)
- Testing
- EEG
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Sedation, Analgesia Assessment
Study Comparing Atomizerd Midazolam & Fentanyl and Dexmedomidine for Procedural Sedation in Adult and Pediatric Patient (2 to 60 Years Old)
To evaluate the depth of sedation, as well as onset, and recovery times, satisfaction of sedation , adverse events associated with Atomized Midazolam \& Fentanyl and Dexmedetomidine during procedural sedation in a diverse…
- Trial name
- NCT07166666
- Testing
- atomizer, rescue medication, Midazolam
- Where
- Oman
- Volunteers
- 128 people
- Sponsor
- Oman Medical Speciality Board
Dental Caries in Children, Pediatric Dental Sedation
Comparing Pediatric Dental Oral Sedation Outcomes With and Without Meperidine in Children Aged 3-7 Years
The primary objective of this randomized controlled trial is to assess the effects of oral sedation using midazolam and hydroxyzine with and without meperidine (a narcotic) on sedation outcomes in pediatric dental patients…
- Conditions
- Dental Caries in Children, Pediatric Dental Sedation, Meperidine, Hydroxyzine
- Trial name
- NCT04068948
- Testing
- Meperidine, Hydroxyzine, Midazolam
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Washington
Pain, Procedural, Procedural Anxiety
Evaluating the Feasibility of VR for Pediatric Renal Biopsies
The purpose of this study is to assess the use of virtual reality (VR) as an adjunct or alternative to pharmacologic sedation in pediatric patients undergoing renal biopsy.
- Conditions
- Pain, Procedural, Procedural Anxiety, Sedation Complication
- Trial name
- NCT05267704
- Testing
- Oculus Go Virtual Reality Headset
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Children Requiring Sedation for MRI/CT
The Incidence and Nature of Adverse Events During Pediatric Sedation for MRI/CT in One Korean University Hospital: Prospective Study
Sedation and anesthesia for which to perform diagnostic imaging represents a rapidly growing field of practice, especially in children. Propofol is the most common sedative drug administered for MRI/CT.
- Trial name
- NCT01855555
- Testing
- sedation with propofol
- Where
- South Korea
- Volunteers
- 2,948 people
- Sponsor
- Yonsei University
Mental Health, Anxiety
Anxiety in Children and Families During MRI Under Anesthesia
This prospective randomized controlled study evaluates the impact of age-appropriate therapeutic play and structured parental briefing on perioperative anxiety during pediatric MRI under sedation.
- Trial name
- NCT07693309
- Testing
- Multi-modal Psychological Preparation
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Afyonkarahisar Health Sciences University
Inhalation Anesthesia
Comparing Nebulized Ketamine,Nebulized Ketamine and Precedex and IM Ketamine for Analgesia in Pediatric Burn
The present study compares efficacy of nebulised ketamine and combination of nebulised dexmedetomidine and ketamine and intramuscular ketamine for procedural sedation and analgesia in pediatric burn injuries
- Trial name
- NCT07086690
- Testing
- Group (1): Patients will receive nebulized ketamine (2 mg/kg), Group (2): Patients will receive nebulized combination of dexmedetomidine and ketamine (1 μg/kg + 1 mg/kg), Patients will receive intramuscular ketamine (4 mg/kg, intramuscularly) 15 mins before starting the procedure.
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Analgesia
Lorazepam for the Analgosedation of Pediatric Patients in Mechanical Ventilation.
The aim of this study is to better define the pharmacokinetic and pharmacodynamic profile of lorazepam for the analgosedation in pediatric intensive care unit.
- Trial name
- NCT04646135
- Testing
- Lorazepam 4 mg/ml
- Volunteers
- 9 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Failed Moderate Sedation During Procedure, Ketamine Adverse Reaction
Intranasal Ketamine for Pediatric Procedural Sedation: a Feasibility Study
The purpose of this study is to evaluate the feasibility of intranasal ketamine for adequate sedation of children undergoing minor procedures in the Emergency Department.
- Trial name
- NCT03067974
- Testing
- Ketamine Hcl 100Mg/Ml Inj
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Arizona
Trauma, Fractures, Closed
Intranasal Versus Intravenous Ketamine for Procedural Sedation in Children With Non-operative Fractures
This a randomized clinical trial involving children with non-operative fractures presenting the emergency department randomized either to intranasal or intravenous ketamine.
- Conditions
- Trauma, Fractures, Closed, Children, Only, Deep Sedation
- Trial name
- NCT03781817
- Testing
- Intravenous Ketamine, Intranasal Ketamine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Alabama at Birmingham
Pediatric Sedation, Clonidine Sedation
Premedication in Children: a Clinical Trial Comparing Oral Ketamine and Oral Clonidine With Respect to Sedation Level and Opioid Consumption in Pediatrics Undergoing Elective Lower Abdominal Day-case Surgery.
Aim of the work Is to compare between oral ketamine and oral clonidine regarding the level of sedation pre and postoperatively in addition the need of opioids administration intraoperative in children undergoing elective lower…
- Conditions
- Pediatric Sedation, Clonidine Sedation, Ketamine Sedation
- Trial name
- NCT07461376
- Testing
- Oral Clonidine (OC)
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Cairo University
Analgesia, Deep Sedation
Implementation and Evaluation of a Pediatric Nurse-driven Sedation Protocol in a PICU
Management of analgesia and sedation is an integral component of the medical care of a critically-ill child. Its role is to assure comfort and safety to a patient undergoing painful cares and technical procedures; it can also be…
- Trial name
- SEDATIDE (NCT02829710)
- Testing
- Nurse-driven sedation protocol
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Hospices Civils de Lyon
Sedation
Effect & Safety of Inhaled Isoflurane vs IV Midazolam for Sedation in Mechanically Ventilated Children 3-17 Years Old
This is a study to compare safety and efficacy of inhaled isoflurane delivered by the AnaConDa-S (Anaesthetic Conserving Device (ACD)) versus intravenous midazolam for sedation in mechanically ventilated children admitted to an…
- Trial name
- IsoCOMFORT (NCT04684238)
- Testing
- Midazolam, Isoflurane
- Where
- 24 sites in France, Germany and 3 more
- Volunteers
- 94 people
- Sponsor
- Sedana Medical
Conscious Sedation, Simple Lacerations Less Than 4 cm
A Comparison of Intranasal Midazolam and Nitrous Oxide (N2O) Minimal Sedation for Minor Procedures in a Pediatric Emergency Department
The objective of this project is to compare the sedative effects of intranasal midazolam versus inhaled nitrous oxide (N2O) for minor procedures in the pediatric emergency department.
- Conditions
- Conscious Sedation, Simple Lacerations Less Than 4 cm, Lumbar Punctures, Minor Incision Drainage of Abscesses Not Requiring Extensive Debridement
- Trial name
- NCT03085563
- Testing
- Nitrous Oxide, Midazolam
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Colorado, Denver
Monitored Anesthesia Care, Respiratory Monitoring
Importance of Integrated Pulmonary Index in Pediatric Bronchoscopy
Integrated Pulmonary Index (IPI) is a tool that provides numerical values on a scale of 1-10 based on physiological parameters such as peripheral oxygen saturation (SpO2), pulse rate, respiratory rate, end-tidal carbon dioxide…
- Trial name
- NCT05137587
- Testing
- Integrated Pulmonary Index (IPI) monitoring, propofol, ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
Child, Intensive Care Unit Acquired Weakness
Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children
While mortality in U.S. pediatric intensive care units (PICUs) is improving, surviving children frequently develop persistent physical, cognitive, and psychological impairments.
- Conditions
- Child, Intensive Care Unit Acquired Weakness, Critical Illness, Hospital Acquired Pressure Ulcer
- Trial name
- PICU Up! (NCT04989790)
- Testing
- PICU Up!
- Where
- 11 sites in United States
- Volunteers
- 1,470 people
- Sponsor
- Johns Hopkins University
Headache, Tumor
Dexmedetomidine and Propofol for Pediatric MRI Sedation
The purpose of this study is to compare the results of combining two anesthetic medications (dexmedetomidine and propofol) in low doses with a standard dose of a single drug that is commonly used to provide sedation/anesthesia…
- Conditions
- Headache, Tumor, Seizure Disorder, Neurofibromatoses
- Trial name
- NCT03513757
- Testing
- propofol, Dexmedetomidine, Glycopyrrolate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical College of Wisconsin