Clinical trials: Peptic Ulcers
Helicobacter Pylori Infection
Prevalence and Risk Factors of Helicobacter Pylori Infection in Children and Young Adults
Helicobacter pylori is a gram-negative bacterium that resides in the stomach and can cause inflammation leading to long-term effects, such as gastric ulcers, cancer, and lymphoma of the stomach mucosal linings Previous research…
- Trial name
- NCT05830357
- Where
- Egypt
- Volunteers
- 667 people
- Sponsor
- Sohag University
Achlorhydria, Gastrinoma
Evaluating Patients With Abnormal Levels of Gastric Acid
This study is used by the Digestive Diseases Branch to evaluate patients with suspected abnormalities in the secretion of gastric acid.
- Conditions
- Achlorhydria, Gastrinoma, Zollinger Ellison Syndrome
- Trial name
- NCT00001240
- Where
- United States
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Gastritis Chronic, Gastroduodenitis
To Develop Methods for the Rehabilitation of Chronic Gastroduodenal Pathology in Children.
The object of the study will be children and adolescents from 6 to 15 years old, living in the city of Tashkent and in the Tashkent region.
- Conditions
- Gastritis Chronic, Gastroduodenitis, Peptic Ulcer, Duodenal Ulcer
- Trial name
- NCT04702542
- Testing
- Enteral oxygen therapy
- Where
- Uzbekistan
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Tashkent State Medical University (Tashkent Pediatric Medical Institute), Uzbekistan
Reflux Esophagitis
Nexium Capsules S-CEI for Justification of Esomeprazole in Acid Related Disease for Reflux Symptom Healing Based on Patient Clinical Outcomes
The objective of this investigation is to collect following data in patients given NEXIUM capsule (NEXIUM) in usual post-marketing use.
- Trial name
- NCT02477475
- Where
- 47 sites in Japan
- Volunteers
- 1,595 people
- Sponsor
- AstraZeneca
Reflux Esophagitis
Special Drug Use Surveillance of Vonoprazan for "Maintenance Therapy of Reflux Esophagitis: Long-term Use"
The purpose of this survey is to evaluate the safety and effectiveness of long-term administration of vonoprazan tablets when used as maintenance therapy for reflux esophagitis in routine clinical settings.
- Trial name
- NCT03214081
- Testing
- Vonoprazan
- Where
- Japan
- Volunteers
- 1,237 people
- Sponsor
- Takeda
Upper Gastrointestinal Bleeding
A Double Blind Study Comparing Two Doses of IV Esomeprazole After Successful Endoscopic Therapy
A bleeding peptic ulcer remains a serious medical problem with significant morbidity and mortality. Endoscopic therapy significantly reduces further bleeding, surgery, and mortality in patients with bleeding peptic ulcers and is…
- Trial name
- NCT01275937
- Testing
- Esomeprazole
- Where
- Taiwan
- Volunteers
- 65 people
- Sponsor
- Taipei Medical University
Gastroesophageal Reflux Disease (GERD), Peptic Ulcers
Long-term Pantoprazole Trial in Patients With Symptoms of Chronic Acid Peptic Complaints (BY1023/VMG-708)
Gastroesophageal reflux disease (GERD) is a medical condition affecting the stomach and esophagus. GERD might occur when the lower esophageal sphincter does not close properly and stomach contents leaks back (refluxes) into the…
- Trial name
- NCT00261300
- Testing
- Pantoprazole
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Takeda
Voice Disorders, Gastroesophageal Reflux
Quantifying Effects of Treatment of Pediatric Dysphonia
The diagnosis and management of childhood dysphonia is a significant clinical problem; however, there have been few studies aimed at defining standard assessment methods for pediatric dysphonia.
- Trial name
- NCT00237679
- Testing
- Neuromuscular Electrical Stimulation, Unstimulated
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Wisconsin, Madison
Reflux Esophagitis
Omepral® Tablets Special Clinical Experience Investigation in Patients With Erosive Esophagitis
This open label, non-interventional study is to compare the efficacy of Omepral® tablet and any other treatments excepting proton pump inhibitors (PPIs) for the treatment of various type of acid reflux related symptoms in…
- Trial name
- OMAREE (NCT00859287)
- Volunteers
- 10,703 people
- Sponsor
- AstraZeneca
Reflux Esophagitis, Gastric Ulcer
A Study of Esomeplazole (D961H) in Japanese Paediatric Patients With Reflux Esophagitis, Gastric Ulcer or Duodenal Ulcer
This is an open label, parallel group, multi-centre, phase III study to assess the safety and efficacy of D961H in maintenance therapy following initial healing therapy in Japanese paediatric patients with reflux esophagitis, and…
- Conditions
- Reflux Esophagitis, Gastric Ulcer, Duodenal Ulcer
- Trial name
- NCT03553563
- Testing
- D961H capsule 10mg, D961H sachet 10mg
- Where
- 15 sites in Japan
- Volunteers
- 50 people
- Sponsor
- AstraZeneca
Peptic Ulcer, Helicobacter Pylori Infection
The Prevalence of Helicobacter Pylori in Shanghai, 2013 to 2019
The study was a cross-sectional single-center study, conducted at Renji Hospital, Shanghai Jiaotong university school of medicine.
- Trial name
- NCT04636866
- Testing
- NO intervention
- Where
- China
- Volunteers
- 400,000 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Peripheral Vascular Access in Pediatric Patients, Peptic Ulcer
The Effect of Vascular Imaging Devices on Success Rates of Peripheral Vascular Access in Pediatric Patients
The study was designed as a prospective, observational study. Pediatric patients under 18 years of age scheduled for peripheral vascular access placement during day-case surgery or non-operating room anesthesia (NORA) will be…
- Conditions
- Peripheral Vascular Access in Pediatric Patients, Peptic Ulcer, Cataract, Crohn's Disease
- Trial name
- NCT07315711
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Sibel Seçkin Pehlivan
Chronic Gastritis Caused by Helicobacter Pylori
Effect of Chicken Egg Antibody (IgY) on Patients With Chronic Gastritis
H. pylori positive patient volunteers that passed the selection criteria are recruited and divided into a test and a control group.
- Trial name
- NCT02721355
- Testing
- GastimunHP
- Where
- Vietnam
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Immunology Research Institute in Gifu
Peptic Ulcer
Administration of High-Dose Intravenous Proton Pump Inhibitor for Upper Gastrointestinal Bleeding Prior to Endoscopy
To evaluate if intravenous PPI infusion, when administered prior to endoscopy, hastens resolution of bleeding stigmata and thereby facilitates endoscopic examinations and reduces the need for endoscopic treatment.
- Trial name
- NCT00164866
- Testing
- Omeprazole
- Where
- China
- Volunteers
- 638 people
- Sponsor
- Chinese University of Hong Kong
Gastric Ulcer, Duodenal Ulcer
Rabeprazole Specific Clinical Experience Investigation for the Long-term Combination Therapy With Low-dose Aspirin
To investigate the safety and efficacy of long-term combination therapy with rabeprazole and low-dose aspirin.
- Trial name
- NCT02423187
- Testing
- No Intervention
- Where
- 3 sites in Japan
- Volunteers
- 1,568 people
- Sponsor
- Eisai Co., Ltd.
Peptic Ulcer
Efficacy of Proton Pump Inhibitor in Prevention of Clopidogrel-related Peptic Ulcer
Proton Pump Inhibitors (PPI) can prevent the recurrence of peptic ulcer in clopidogrel users.
- Trial name
- NCT01138969
- Testing
- esomeprazole
- Where
- Taiwan
- Volunteers
- 165 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Gastro Esophageal Reflux, Gastric Ulcer
Comparison Between Two Types of Sedation for Elective Upper Endoscopy Procedures
Sedation is defined as the act of administrating a sedative drug to produce a state of calm or sleep. Sedation is commonly given to a patient in hospital settings to provide a tolerable and pleasant experience by relieving…
- Conditions
- Gastro Esophageal Reflux, Gastric Ulcer, Sedation Complication
- Trial name
- NCT04410211
- Testing
- Sevoflurane, Midazolam injection
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Gastric Ulcer, Duodenal Ulcer, and Reflux Esophagitis
Drug Use Surveillance of Vonoprazan for "Gastric Ulcer, Duodenal Ulcer, and Reflux Esophagitis"
The purpose of this survey is to evaluate the safety and effectiveness of vonoprazan tablets in patients with gastric ulcer, duodenal ulcer, and reflux esophagitis in the routine clinical setting.
- Trial name
- NCT03214952
- Testing
- Vonoprazan
- Where
- Japan
- Volunteers
- 3,183 people
- Sponsor
- Takeda
Helicobacter Infections, Gastritis
Tailored Treatment of H. Pylori Infection Based Polymorphisms of CYP2C19 and 23S rRNA of H. Pylori
The eradication rate of the standard H. pylori eradication therapy (such as the triple therapy with a proton pump inhibitor [PPI], amoxicillin and clarithromycin) depends on bacterial susceptibility to clarithromycin and…
- Conditions
- Helicobacter Infections, Gastritis, Gastric Ulcer, Duodenal Ulcer
- Trial name
- NCT00149084
- Testing
- Lansoprazole, clarithromycin, amoxicillin
- Where
- Japan
- Volunteers
- 296 people
- Sponsor
- Hamamatsu University