Clinical trials: Periodontal Health
Caries, Gum Disease
Randomized Clinical Trial: Oral Health Package Law and Fluor Varnish Impact on Schoolchildren in Merida, Mexico
Study aimed at evaluating the impact on oral health of the "Ley del Paquete de Salud Bucal" (daily school brushing program) combined, or not, with the application of fluoride varnish in schoolchildren from 6 to 8 years old who…
- Trial name
- DBMX (NCT05960110)
- Testing
- Fluoride varnish, Fluoride toothpaste
- Where
- Mexico
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Anahuac Mayab University
Primary Immune Deficiency Disorder, Periodontitis
Investigation of Dental Health in Children With Neutrophil Defects: A Clinical Study
Title: Investigation of neutrophil defects associated with periodontal disease and tooth loss in children. A clinical study. Objectives: The primary objective of this study is: To investigate presence of periodontal disease and…
- Trial name
- GOSH (NCT03069079)
- Testing
- Oral hygiene advice, non surgical periodontal treatment
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- Queen Mary University of London
Preterm Birth, Low Birth Weight
Periodontal Disease and Small Vulnerable Newborns in Rural Nepal: A Community-based Trial
Periodontal disease in pregnant women has been implicated as a potential risk factor for adverse pregnancy outcomes, including being born preterm, small-for-gestational age, and/or low birth weight.
- Conditions
- Preterm Birth, Low Birth Weight, Small Vulnerable Newborn, Small-for-gestational Age
- Trial name
- NCT07553286
- Testing
- A package of oral health interventions, including a daily antiseptic oral rinse (alcohol-free cetylpyridinium chloride (0.075%))
- Volunteers
- 2,280 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Caries, Gingivitis
School-based Oral Health Education Program Using Experiential Learning
The aim of this project was to compare the effectiveness of experiential learning (EL) and traditional lecturing (TL) school-based oral health education on the oral health knowledge, attitude, habits, oral hygiene, gingival…
- Trial name
- NCT02320162
- Testing
- Experiential learning oral health education
- Volunteers
- 351 people, healthy volunteers welcome
- Sponsor
- Matina Angelopoulou
Peri-Implant Health, Peri-Implantitis and Peri-implant Mucositis
Monitoring of Implant Diseases: Diagnosis and Monitoring With aMMP-8 Test Technology
68 patients underwent the aMMP-8 chair-side test as well as clinical traditional measurement methods. Those who had one or more implants in their mouth were selected as patients.
- Trial name
- IMP_TRE (NCT06761521)
- Testing
- Peri-Implantitis and Peri-implant mucositis
- Where
- Finland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hanna Lahteenmaki
Orthodontic Appliance Complication, Gingival Overgrowth
Scalpel Versus Laser Gingivectomy in Orthodontic Patients in the Management of Periodontal Health
Patients undergoing orthodontic treatment with fixed appliances usually develop gingival enlargement (GE). Its development is usually attribute to chronic inflammation, and may cause both esthetic and functional problems for the…
- Trial name
- NCT03514316
- Testing
- Scalpel Gingivectomy, Laser Gingivectomy, Nonsurgical periodontal treatment
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Rome Tor Vergata
Innate Immunity, Periodontal Health
Passive Smoking and LL-37 in Children
This study investigates the salivary LL-37 in passive smoking-exposed and unexposed children and the association between salivary LL-37 levels and periodontal clinical parameters in these children.Unstimulated salivary samples…
- Trial name
- NCT03639376
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Oral Health, Dental Caries
The Use of Artificial Intelligence in the Dental X-rays Analysis
This cross-sectional study aims to perform a population-based assessment of the incidence of decay, dental fillings, root canal fillings, endodontic lesions, implants, implant and dental abutment crowns, pontic crowns, and…
- Conditions
- Oral Health, Dental Caries, Periapical Diseases, Tooth Loss
- Trial name
- NCT06258798
- Testing
- Taking a dental X-ray
- Where
- Poland
- Volunteers
- 1,025 people
- Sponsor
- Hospital of the Ministry of Interior, Kielce, Poland
Allogeneic Stem Cell Transplantation
Xylitol BSI Multisite - Reduction of Bloodstream Infections From Oral Organisms in Pediatric Stem Cell Transplant
Bloodstream infections (BSI) caused by bacteria translocating across injured oral mucosa are a significant cause of morbidity and mortality in patients undergoing stem cell transplantation (SCT).
- Trial name
- NCT05579639
- Testing
- Xylitol
- Where
- 3 sites in United States
- Volunteers
- 256 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Gingivitis
A Person-centered, Theory-based, Intervention - Method Development Through the Integration of Digital Technology.
Studies have shown that Swedish adolescents have poor oral hygiene and with high prevalence of gingivitis. Therefore, more effective preventive programs in dental care are needed.
- Trial name
- NCT07306117
- Testing
- Person-centered, theory-based, intervention
- Where
- Sweden
- Volunteers
- 25 people
- Sponsor
- Vastra Gotaland Region
Oral Health Related Quality of Life (OHRQoL), Early Childhood Caries (ECC)
Assessment of Oral Health-Related Quality of Life in Preschool-Aged Children in Alto Alentejo
The observational study aims to improve understanding of Oral Health-Related Quality of Life (OHRQoL) among preschool children in the District of Portalegre, Portugal, by examining the roles of sociodemographic, behavioral, and…
- Conditions
- Oral Health Related Quality of Life (OHRQoL), Early Childhood Caries (ECC), Traumatic Dental Injuries, Gingivitis
- Trial name
- NCT07648121
- Where
- Portugal
- Volunteers
- 454 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Caries, Dental, Periodontal Diseases
The Effectiveness of an Oral Health Education Programme of Adolescents in Hong Kong
This project aims to evaluate the relative efficacy of a peer-led intervention based on the Social Cognitive Theory and Health Belief Model versus the control (only pamphlet delivery) on increasing the prevalence of healthy oral…
- Trial name
- NCT03694496
- Testing
- peer-led theory-based intervention group
- Where
- Hong Kong
- Volunteers
- 1,184 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Secondhand Smoke Exposure, Children
Evaluation of Periodontal Health, Salivary Cotinine and S100A8/A9 Levels in Children Exposed to Passive Smoking
The periodontal health of children exposed to passive smoking will be evaluated by S100A8 and S100A9 levels.
- Conditions
- Secondhand Smoke Exposure, Children, Inflamation, Cotinine Levels
- Trial name
- NCT06791707
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Periodontitis, Healthy
Effect Of Scaling and Root Planning on ALP in Saliva and GCF In Periodontitis Patients Compared With Healthy Individuals
The goal of this [interventional clinical trial] is to test effect of scaling and root plaining on Alkaline phosphatase in Saliva and Gingival crevicular fluid in periodontitis patients compared with healthy subjects The…
- Trial name
- NCT06048016
- Testing
- Scaling and Root Planning
- Where
- Egypt
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Cairo University
Black Stains
Assessment of Black Stains on Teeth in Relation to Salivary Parameters, Periodontal Health, and Body Mass Index in Children
Objective The aim of this study is to compare salivary flow rate, salivary pH, salivary buffering capacity, plaque index, gingival index, DMFT/dft indices, and body mass index (BMI) in systemically healthy children aged 5-10…
- Trial name
- NCT06985446
- Testing
- Study Group:Black stain-positive, Control Group: Black stain-negative
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Orthodontic Appliance Complication, Plaque, Dental
Regular Home Use of Dual-light Photodynamic Therapy on Oral Health in Adolescents Undergoing Fixed Orthodontic Treatment
This study is designed to determine the efficacy of the Lumoral method on oral health in adolescents undergoing fixed orthodontic treatment.
- Conditions
- Orthodontic Appliance Complication, Plaque, Dental, Gingival Inflammation
- Trial name
- NCT05825742
- Testing
- Lumoral Treatment, Standard oral health instructions
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Koite Health Oy
Gingivitis
The Effect of Probiotics on Gums Health and Bad Breath
the study is about using healthy bacteria to improve the overall gingival and overall health and prevent or decrease the bad odor of the mouth caused by bad bacteria
- Trial name
- NCT06910397
- Testing
- Probiotic Arm
- Where
- Iraq
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Orthodontic Appliances, Adverse Effects,Gingivitis, Dental Plaque, Periodontal Diseases
Digital Manufacturing and Periodontal Performance of CAD/CAM-Customized Orthodontic Molar Bands Compared With Standard Stainless-Steel Bands
his prospective randomized clinical trial aimed to compare periodontal outcomes associated with CAD/CAM-customized orthodontic molar bands and conventional preformed stainless-steel molar bands in adolescents undergoing fixed…
- Trial name
- NCT07526805
- Testing
- Stainless-Steel Orthodontic Molar Bands
- Where
- Romania
- Volunteers
- 180 people
- Sponsor
- Dimitrie Cantemir University
Malocclusion, Angle Class II, Division 1
Evaluating Laser and Piezocision vs. Piezocision Alone on Root Resorption and Gingival Health During Tooth Retraction
This trial aims to determine whether using a special laser (low-level laser therapy, or LLLT) in combination with a minor surgical procedure (piezocision) can safely accelerate orthodontic treatment.
- Trial name
- NCT07442825
- Testing
- Flapless Corticotomy (Piezocision), Level Laser Therapy (LLLT), Traditional treatment
- Where
- Syria
- Volunteers
- 66 people
- Sponsor
- Damascus University
Periodontitis
Effectiveness of Medical Coaching in Enhancing Periodontal Health and Lifestyle
Periodontitis is a chronic inflammatory disease that adversely influences the supporting tissues of the teeth. It is primarily characterized by the accumulation of bacterial plaque and the host immune response.
- Trial name
- MCOH (NCT06887946)
- Testing
- Medical couching and traditional
- Where
- Italy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Bari Aldo Moro