Clinical trials: Persistent
Tourette's Disorder, Persistent (Chronic) Motor or Vocal Tic Disorder
Internet-delivered Behaviour Therapy for Children and Adolescents With Tourette's Disorder
The purpose of this trial is to evaluate the clinical efficacy, 12-month durability, and cost-effectiveness of BIP TIC - a therapist-guided and parent-guided internet-delivered behavioural intervention for children and…
- Trial name
- NCT03916055
- Testing
- Exposure and response prevention (ERP), Education on tics
- Where
- Sweden
- Volunteers
- 221 people
- Sponsor
- Karolinska Institutet
Vegetative State
The Prognostic Value of Pupil Near Response in UWS Patients
Previous studies suggest that the stimulus of pupil near response (PNR) may be a conscious perception of a blurred image. Moreover, PNR is a reflex that can be objectively observed and with no motor output, suggesting it might be…
- Trial name
- NCT02832492
- Testing
- pupil near response
- Volunteers
- 20 people
- Sponsor
- Wentao Zeng
Disorder of Consciousness, Minimally Conscious State
Simultaneously PET/MRI in Prolonged DOC Patients
Recently introduced hybrid PET/MR scanners provide the opportunity to measure simultaneously, and in direct spatial correspondence, both metabolic demand and functional activity of the brain, hence capturing complementary…
- Conditions
- Disorder of Consciousness, Minimally Conscious State, FDG-PET, Rs-fMRI
- Trial name
- NCT04164680
- Testing
- Multimodal Neuroimaging
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hangzhou Normal University
Minimally Conscious State, Vegetative State
Validation of the Chinese Version of the SECONDs
The aim of this study was to translate the SECONDs from English into Chinese and determine the validity of this Chinese version
- Trial name
- NCT04687553
- Testing
- Simplified Evaluation of CONsciousness Disorders (SECONDs)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Hangzhou Normal University
Asthma Severe Persistent Uncontrolled
Use of Nucala in Severe Asthma
The Severe Heterogeneous Asthma Research collaboration, Patient-centred (SHARP) is set up to harmonise severe asthma management across Europe and unravel underlying heterogeneity in a patient-centred way.
- Trial name
- UNISA (NCT05441059)
- Testing
- Mepolizumab 100 MG
- Where
- Netherlands
- Volunteers
- 2,100 people
- Sponsor
- Frisius Medisch Centrum
Cervical Intraepithelial Neoplasia, Cervical Cancer
Lot Consistency Clinical Trial of of Recombinant HPV Bivalent Vaccine in 9 to14 Years Old Healthy Female
This study is to evaluate lot-lot consistency of Recombinant Human Papillomavirus Bivalent (Types 16, 18) Vaccine (Escherichia coli) .
- Conditions
- Cervical Intraepithelial Neoplasia, Cervical Cancer, Vaginal Intraepithelial Neoplasia, Vulvar Intraepithelial Neoplasia
- Trial name
- NCT05426148
- Testing
- Recombinant Human Papillomavirus Bivalent (Types 16, 18) Vaccine (Escherichia coli) / Cecolin®
- Where
- China
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Xiamen Innovax Biotech Co., Ltd
Meconium Aspiration Syndrome, Persistent Pulmonary Hypertension of Newborn
Oral Sildenafil in Persistent Pulmonary Hypertension Secondary to Meconium Aspiration Syndrome in Newborns
The purpose of this study is to to study the role of oral Sildenafil in Persistent Pulmonary Hypertension of Newborn (PPHN) secondary to Meconium Aspiration Syndrome (MAS) in newborns and to study risk factors of MAS developing…
- Trial name
- OSiNPH (NCT01757782)
- Testing
- Oral Sildenafil
- Where
- India
- Volunteers
- 96 people
- Sponsor
- Sir Takhtasinhji General Hospital
New Daily Persistent Headache (NDPH)
Endogenous Modulation and Central Sensitization in New Daily Persistent Headache ( NDPH ) in Children
New daily persistent headache (NDPH) is a primary headache disorder characterized by the daily and unremitting headache pain patients experience with a distinct onset.
- Trial name
- EMCS-NDPH (NCT03447782)
- Testing
- Naltrexone HCl (Bulk) Powder
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Severe Persistent Asthma
Identification of Serum Biomarkers for CD15+ Hypodense Neutrophils in Severe Asthma
The goal of this study is to identify a serum biomarker(s) that can detect increased levels of a population of CD15+ hypodense neutrophils termed low-density granulocytes (LDG) in the blood of patients with severe persistent…
- Trial name
- NCT02659618
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Rush University Medical Center
Persistent Pulmonary Hypertension of the Newborn
NEURodevelopmental Outcome After Persistent Pulmonary Hypertension Of the Newborn
Neonatal pulmonary hypertension is a rare but serious condition resulting from a lack of adaptation to extra-uterine life in some newborns.
- Trial name
- NEUROPHON (NCT04841070)
- Testing
- Ages & Stages Questionnaires®, Third Edition (ASQ3)
- Where
- France
- Volunteers
- 55 people
- Sponsor
- University Hospital, Toulouse
Persistent Asthma
A 12-week Safety and Efficacy Study of Beclomethasone Dipropionate (80 and 160 mcg/Day) Delivered Via Breath-Actuated Inhaler (BAI) in Patients >=12 Years Old With Persistent Asthma
This is a randomized, double-blind, placebo-controlled parallel-group study. Participants will be randomly assigned to receive treatment with beclomethasone dipropionate at a dosage of 80 or 160 mcg/day delivered via a…
- Trial name
- NCT02040779
- Testing
- Beclomethasone dipropionate breath-actuated inhaler, albuterol/salbutamol
- Where
- 47 sites in United States
- Volunteers
- 273 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Persistent Asthma
Long-Term Safety Study of Fluticasone Propionate (Fp) Multidose Dry Powder Inhaler (MDPI) and Fluticasone Propionate/Salmeterol (FS) MDPI in Patients With Persistent Asthma
The primary objective of the study is to evaluate the long-term safety of fluticasone propionate (Fp) inhalation powder in 2 strengths and fluticasone propionate/salmeterol inhalation (FS) powder in 2 strengths when administered…
- Trial name
- NCT02175771
- Testing
- Fp MDPI, FS MDPI, FLOVENT HFA
- Where
- 101 sites in United States
- Volunteers
- 758 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Persistent Asthma
Study to Assess the Efficacy and Safety of Beclomethasone Dipropionate in Adolescent and Adult Patients 12 Years of Age and Older With Persistent Asthma
The primary objective of this study is to evaluate the efficacy of beclomethasone dipropionate administered via BAI at a dose strength of 40 or 80 mcg per oral inhalation (320 or 640 mcg/day, respectively) compared with placebo…
- Trial name
- NCT02513160
- Testing
- Beclomethasone Dipropionate 640, Beclomethasone dipropionate via 320 mcg BAI, albuterol/salbutamol
- Where
- 75 sites in United States
- Volunteers
- 713 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Persistent Tic Disorders, Tourette Disorder
Online-Delivered Comprehensive Behavioral Intervention for Tics-Enhanced (CBIT-E)
The purpose of this pilot trial is to examine the preliminary efficacy of online-delivered Comprehensive Behavioral Intervention for Tics - Enhanced (CBIT-E).
- Trial name
- NCT05050734
- Testing
- Comprehensive Behavioral Intervention for Tics - Enhanced (CBIT-E)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Marquette University
Pulmonary Hypertension, Familial Persistent, of the Newborn
A Study To Evaluate Safety And Efficacy Of IV Sildenafil In The Treatment Of Neonates With Persistent Pulmonary Hypertension Of The Newborn
This study will evaluate whether IV sildenafil can reduce the time on inhaled nitric oxide treatment and reduce the failure rate of available treatments for persistent pulmonary hypertension of the newborn.
- Trial name
- NCT01720524
- Testing
- iv sildenafil
- Where
- 42 sites in United States, Belgium and 10 more
- Volunteers
- 59 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Juvenile Idiopathic Arthritis, Persistent Knee Arthritis
Genicular Nerve Block in Juvenile Idiopathic Arthritis
N=104 juvenile idiopathic arthritis patients diagnosed after ILAR criteria with unilateral persistent knee arthritis. They will be randomly assigned into two groups; group 1 will receive genicular nerve block, group 2…
- Conditions
- Juvenile Idiopathic Arthritis, Persistent Knee Arthritis, no Intra-articular Injection in the Last 3 Months, no Other Cause for Chronic Kneearthritis
- Trial name
- NCT04687930
- Testing
- genicular nerve block, intra-articular steroid injection
- Where
- Egypt
- Volunteers
- 104 people
- Sponsor
- Sohag University
Disorders of Consciousness, Severe Brain Injury
Use of Analgesic Treatment to Reduce Signs of Pain in Patients With Disorders of Consciousness.
The purpose of this study is to characterize and improve pain and nociception management in patients with disorders of consciousness (DOC).
- Conditions
- Disorders of Consciousness, Severe Brain Injury, Post-comatose Non-communicative Patients, Vegetative State
- Trial name
- NCT04330547
- Testing
- Analgesic administration
- Where
- Belgium
- Volunteers
- 19 people
- Sponsor
- University of Liege
Atrial Fibrillation, Persistent
VOLTage Mapping in Atrial Fibrillation
The purpose of this study is to retrospectively analyze electroanatomical data collected during persistent atrial fibrillation ablation procedures, combined with pre-ablation cardiac CT data, in order to: define a new method for…
- Trial name
- VOLT-AF (NCT04832646)
- Testing
- atrial fibrillation ablation
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Central Hospital, Nancy, France
Asthma, Severe Persistent Asthma
Severe Asthma Research Program - Wake Forest University
The mission of SARP is to improve the understanding of severe asthma through the integrated study of the effect of genetics on the clinical and biological features of asthma and to investigate how these change over time.
- Trial name
- SARP3 (NCT01750411)
- Where
- 2 sites in United States
- Volunteers
- 87 people
- Sponsor
- Wake Forest University
Persistent Atrial Fibrillation
Effects of Different Surgical Methods for Persistent Atrial Fibrillation Combined With the Application of Statin Drugs on Left Atrial Function
A total of 164 patients with persistent atrial fibrillation, who are planned to undergo treatment with cryoballoon ablation, will be randomly allocated into two groups.
- Trial name
- NCT03700307
- Testing
- Cryoballoon ablation
- Where
- China
- Volunteers
- 164 people
- Sponsor
- The Second Hospital of Hebei Medical University