Clinical trials: Persistent Asthma
Asthma
A Study of Mometasone Furoate Metered Dose Inhaler in Children With Persistent Asthma (P04223)
The primary objective of this study is to demonstrate the dose-related efficacy, by evaluating morning (AM) lung function at the end of the dosing interval (AM pre-dose percent predicted forced expiratory volume in one second…
- Trial name
- NCT01502371
- Testing
- Mometasone Furoate (MF) Metered Dose Inhaler (MDI), 25 mcg, Mometasone Furoate (MF) Metered Dose Inhaler (MDI), 50 mcg, Mometasone Furoate (MF) Metered Dose Inhaler (MDI), 100 mcg
- Volunteers
- 583 people
- Sponsor
- Organon and Co
Persistent Asthma, Asthma in Children
Asthma Research in Children and Adolescents
The purpose of this study is to assess the evolution of disease control, health-related quality of life, and the risk of severe asthma exacerbations in children and adolescents with persistent asthma in Spain at short, mid and…
- Conditions
- Persistent Asthma, Asthma in Children, Asthma Exacerbation
- Trial name
- ARCA (NCT04480242)
- Testing
- Inhaled Corticosteroids (ICs), Fixed-Dose Combination of Inhaled Corticosteroids and Long- Acting Beta-agonist (ICs/LABA), Other treatments
- Where
- 15 sites in Spain
- Volunteers
- 525 people
- Sponsor
- Parc de Salut Mar
Asthma
Efficacy of Inhaled Albuterol Spiromax® in Subjects With Persistent Asthma With Steady State Pharmacokinetics
The primary objective of this study is to evaluate the efficacy of Albuterol Spiromax® versus placebo in subjects with persistent asthma.
- Trial name
- NCT01747629
- Testing
- Albuterol MDPI
- Where
- 35 sites in United States
- Volunteers
- 160 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Severe Persistent Asthma
Identification of Serum Biomarkers for CD15+ Hypodense Neutrophils in Severe Asthma
The goal of this study is to identify a serum biomarker(s) that can detect increased levels of a population of CD15+ hypodense neutrophils termed low-density granulocytes (LDG) in the blood of patients with severe persistent…
- Trial name
- NCT02659618
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Rush University Medical Center
Asthma
A Randomized Study To Evaluate The Efficacy And Safety Of An Investigational Drug In Adolescent And Adult Subjects With Persistent Asthma.
This study is designed to determine if the investigational drug is effective and safe in individuals with asthma.
- Trial name
- NCT00398645
- Testing
- GW685698X 200mcg,GW685698X 200mcg and 400mcg
- Where
- 82 sites in United States, Australia and 14 more
- Volunteers
- 648 people
- Sponsor
- GlaxoSmithKline
Asthma
Comparison of the Efficacy/Safety of Symbicort® Turbuhaler®,Seretide™ Diskus™ 50/500 µg & Terbutaline Turbuhaler® 0.4 mg
The purpose of this study is to compare the efficacy and safety of a variable dose of Symbicort with a high fixed maintenance dose of another asthma medication, Seretide, in the treatment of asthma.
- Trial name
- NCT00242775
- Testing
- Budesonide/formoterol Turbuhaler, Salmeterol/fluticasone Diskus
- Where
- 143 sites in Argentina, Australia and 15 more
- Volunteers
- 2,100 people
- Sponsor
- AstraZeneca
Asthma, Severe Persistent Asthma
Implications and Stability of Clinical and Molecular Phenotypes of Severe Asthma
The Severe Asthma Research Program III is an NIH cooperative agreement involving 7 clinical centers that encompass a multidisciplinary partnerships between asthma clinician-scientists and scientists with expertise in immunology…
- Trial name
- SARPIII (NCT01748175)
- Testing
- Triamcinolone Acetonide
- Where
- United States
- Volunteers
- 715 people, healthy volunteers welcome
- Sponsor
- Sally E. Wenzel MD
Asthmatic
Influenza Vaccine Feasibility Study in Children With Persistent Asthma
This study is designed to note whether a larger safety study using quadrivalent live attenuated influenza vaccine (LAIV4) versus quadrivalent inactivated influenza vaccine (IIV4)(FLUARIX®), would be feasible in children with…
- Trial name
- NCT02967393
- Testing
- ccIIV4, IIV4
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Vanderbilt University Medical Center
Persistent Asthma
Impact of Lung Flute Therapy on Asthma
We hypothesized that the ability of the Lung Flute to enhance mucus clearance from the lower airways could be used to improve asthma control, if the device is used on a chronic basis.
- Trial name
- NCT02003521
- Testing
- Lung Flute
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Medical Acoustics LLC
Asthma in Children
Use of a Modern Breath Sampling System (the Pneumopipe® Combined With an Array of E-nose Sensors) for the Prediction of Treatment Response in Persistent Asthmatic Children
Due to a large disease heterogeneity, the proper management of childhood asthma may be a challenging task. Despite the screening of lung function is a fundamental tool, spirometry alone may not allow a reliable prediction of the…
- Trial name
- Pneumo-Pred (NCT04326530)
- Testing
- Pneumopipe® (European patent 12425057.2, Rome, Italy), Other assessments
- Volunteers
- 150 people
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Respiratory Tract Infections, Pediatric Respiratory Diseases
Bacterial Lysate In Preventing Asthma
Bronchiolitis is a common viral infection of the small airways of infants and some affected infants will require hospital admission.
- Conditions
- Respiratory Tract Infections, Pediatric Respiratory Diseases, Wheezing
- Trial name
- BLIPA (NCT05064631)
- Testing
- Bacterial Lysate
- Where
- 3 sites in United Kingdom
- Volunteers
- 173 people
- Sponsor
- Queen Mary University of London
Asthma
Beclomethasone Dipropionate HFA in Adult and Adolescent Subjects With Mild to Moderate Persistent Asthma
Approximately 480 (120 per group) would need to complete the 12 weeks of treatments.
- Trial name
- NCT03835871
- Testing
- 400 µg per day Beclomethasone, 200 µg per day Beclomethasone, 100 µg per day Beclomethasone
- Sponsor
- Adamis Pharmaceuticals Corporation