Clinical trials: Pervasive Development Disorders
Autism Spectrum Disorder, Autism
Group Intervention on Executive Function in Children With Autism Spectrum Disorder
Autism is a developmental disorder characterized by difficulties in social communication, repetitive behaviors, and social interaction.
- Trial name
- NCT05977075
- Testing
- ApisMela protocol, "Unstuck and on Target" protocol
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Autism Spectrum Disorder, Language Development
Predicting Language and Literacy Growth in Children With ASD Using Statistical Learning
The goal of this observational study is to test a reciprocal relationship between statistical learning and the development of language and literacy in first-graders with autism and their non-autistic peers.
- Conditions
- Autism Spectrum Disorder, Language Development, Literacy
- Trial name
- PLAUSL (NCT06332144)
- Testing
- Structural vs. Random sequences of stimuli, Intact vs. Degraded speech, Repeating 5-syllable nonwords or 2-syllable nonwords
- Where
- 2 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Northeastern University
Autism
Neuropsychopathological Study of Autism
Autism or autism spectrum disorder (ASD) is a relatively common (0.3% in Taiwan), multi-factorial, genetically and clinically heterogeneous, childhood-onset neurodevelopmental disorder.
- Trial name
- NCT01677663
- Where
- Taiwan
- Volunteers
- 350 people
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder
Oxytocin in Adolescents With Autism Spectrum Disorders
This study is design to evaluate the influence of oxytocin in some aspects of Autism Spectrum Disorder (ASD), such as, repetitive and stereotyped behavior, social skills, quality of life and disruptive behaviors.
- Trial name
- OXYASD (NCT02007447)
- Testing
- OCYTOCINA - SPRAY NASAL
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo General Hospital
Intellectual Disability, Autism Spectrum Disorder
Harnessing Communication Preferences
The goal of this clinical trial is to evaluate how preference for communication approach (e.g., using a touch talker versus picture cards) impacts treatment maintenance in the context of treatment to reduce challenging behavior…
- Conditions
- Intellectual Disability, Autism Spectrum Disorder, Self-Injurious Behavior, Communication Disabilities
- Trial name
- NCT07278544
- Testing
- PrefFCT, NonPrefFCT
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Joel E. Ringdahl
Autism Spectrum Disorder, Catatonia
Use of MRI and cTBS for Catatonia in Autism
Despite the significant morbidity and mortality associated with catatonia in autism, no diagnostic research has attempted to identify biomarkers for catatonia.
- Conditions
- Autism Spectrum Disorder, Catatonia, Intellectual Disability
- Trial name
- NCT06016764
- Testing
- Continuous Theta Burst in Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Vanderbilt University Medical Center
Autism, Infantile
The Effect of Acceptance and Commitment Therapy
In this randomized control study, investigators will evaluate the effectiveness of the Acceptance and Commitment Therapy (ACT) matrix behavioral protocol compared to Parent Training (PT) programs in improving the psychological…
- Trial name
- ASDMatrix (NCT04909658)
- Testing
- ACT Matrix, PT Protocol
- Where
- Italy
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- S.Anna Rehabilitation Institute
Autism Spectrum Disorder
Improving Dental Care and Oral Health in Children With Autism Spectrum Disorder
A randomized controlled trial (at sites) comparing the efficacy of the established AIR-P Dental Toolkit (control condition) to a combined regimen involving the Dental Toolkit and parent-mediated behavioral intervention…
- Trial name
- NCT03003221
- Testing
- AIR-P Dental Toolkit, Parent Training
- Where
- 2 sites in United States
- Volunteers
- 119 people
- Sponsor
- University of California, Irvine
Autism Spectrum Disorder
Temporal Pole Transcranial Alternating Current Stimulation for Children With Autism Spectrum Disorder
The goal of this open-label randomized controlledl trial is to explore the safety and efficacy of conventional transcranial alternating current stimulation (tACS) and transcranial temporal interference stimulation (tTIS)…
- Trial name
- NCT07045584
- Testing
- Transcranial Alternating Current Stimulation, transcranial Temporal Interference Stimulation
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Fei Li
Autism Spectrum Disorder
Efficiency of Early Intervention for Autism Spectrum Disorder
Intervention for autism spectrum disorder (ASD) in European French-speaking countries is often heterogeneous and poorly evaluated.
- Trial name
- IDEA (NCT02608333)
- Testing
- ESDM-12, control group
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Hôpital le Vinatier
Autism, Autism Spectrum Disorders
A Study of Divalproex Sodium in Children With ASD and Epileptiform EEG
Background: Electroencephalography (EEG) records electric patterns produced by the brain, and can detect conditions such as epilepsy or other l abnormalities that may affect brain function.
- Trial name
- NCT01170325
- Testing
- Divalproex Sodium
- Where
- United States
- Sponsor
- National Institute of Mental Health (NIMH)
Autism Disorder
Triadic Interactions of Families With Autism and Oxytocin
The study will investigate the effects of an intranasal administration of oxytocin (OT) to parents of children with autism spectrum disorders (ASD) on the quality of mother-father-child interactions.
- Trial name
- TAO (NCT01912378)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Anxiety
Effect of a Social Script iPAD Application for Children With Autism Spectrum Disorder
The purpose of the research is to test the effectiveness of the social story intervention delivered using the iPAD application "Going to Imaging" on the anxiety, challenging child behaviors, child injuries and completion rates…
- Trial name
- NCT01655485
- Testing
- Patient teaching
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Autism Spectrum Disorder
The Relationship Between Social Memory Disorders and Sleep Spindles in Children With Autism Spectrum Disorder
Research background and project basis Autism spectrum disorder (ASD) is a lifelong neurodevelopmental disorder characterized by social disorders and repetitive stereotypical behavior.
- Trial name
- NCT06306378
- Testing
- social memory levels and spindle levels
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Autism Spectrum Disorder
Cariprazine Pediatric ASD PK Study
This study will be a multi-center, open-label, parallel-group, multiple-dose study in up to 24 male and female participants aged 5 through 17 years, inclusive, with Autism Spectrum Disorder (ASD).
- Trial name
- NCT04382885
- Testing
- Cariprazine
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- AbbVie
Autism Spectrum Disorder, Intellectual Disability
Facing Your Fears: Adolescents With ASD and Intellectual Disability
Adolescents with ASD and intellectual disability (ID) are a complex and underserved population. Approximately 50% of individuals with ASD/ID experience significant anxiety.
- Conditions
- Autism Spectrum Disorder, Intellectual Disability, Anxiety, Emotion Regulation
- Trial name
- FYF:ASD/ID (NCT05131425)
- Testing
- Facing Your Fears: ASD/ID, Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Autism Spectrum Disorder
Gaming Open Library for Intervention in Autism at Home (GOLIAH /MICHELANGELO)
To meet the required intensive intervention hour for treating children with autism spectrum disorder (ASD), the investigators developed an automated serious gaming platform (11 games) to deliver intensive intervention at home…
- Trial name
- MICHELANGELO (NCT02560415)
- Testing
- Experimental, Comparator
- Volunteers
- 24 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism
Adipose Derived Stem Cell Therapy for Autism
The intent of this clinical study is to answer the questions: 1. Is the proposed treatment safe 2. Is treatment effective in improving the disease pathology of patients with Autism.
- Trial name
- NCT01502488
- Testing
- Fat Harvesting and Stem Cell Injection
- Where
- United States
- Sponsor
- Ageless Regenerative Institute
Autism Spectrum Disorder (ASD)
Modified and Context-Focused Sports Intervention in Adolescents With Autism: Study Protocol
Adolescents with Autism Spectrum Disorder (ASD) typically engage less in physical activities than their typically developing peers, influenced by intrinsic and extrinsic factors.
- Trial name
- ASD (NCT06916988)
- Testing
- Sports Stars Brazil, context-centered therapy
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- Federal University of Minas Gerais
Autism Spectrum Disorder
Effects of Probiotic Consumption in Children With Autism Spectrum Disorder (ASD)
The goal of this clinical trial is to determine the effects of Saccharomyces boulardii (Sb) consumption on Ecuadorian children with a diagnosis of autism spectrum disorder (ASD) and digestive symptoms.
- Trial name
- NCT06568588
- Testing
- S. boulardii CNCM (National Collection of Cultures of Microorganisms) I-745
- Where
- Ecuador
- Volunteers
- 66 people
- Sponsor
- Universidad San Francisco de Quito
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