Clinical trials: Pharynx
Deglutition Disorders
Dysphagia on the Intensive Care Unit
Recording of routine practice patterns to detect and/or treat Dysphagia on the ICU via interview of local colleagues. This will not allow to record generalizable data, but will reflect the actual routine standard of care.
- Trial name
- DICE-SWISS (NCT03487510)
- Testing
- NO interventions apply
- Where
- Switzerland
- Volunteers
- 49 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Nasopharyngeal Cancer
A Study of Nasopharyngeal Carcinoma From Guangdong
This prospective cohort study aims to establish prognostic models, to discover toxicity associated predictors and to validate randomized trials in clinical practice.
- Trial name
- NCT03003182
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Sun Yat-sen University
Cancer of Esophagus, Gastric Cancer
Analysis of Body Composition in Relation to Outcome After Surgery in a Cohort of Patients With Esophageal Cancer
The occurrence of dysphagia is a well-known early feature of esophageal cancer that may reduce caloric intake and thus cause weight loss. Sarcopenia is considered to be a consequence of such involuntary nutritional restriction.
- Trial name
- NCT03032224
- Testing
- Resection of the esophagus and the gastroesophageal junction
- Where
- Sweden
- Volunteers
- 76 people
- Sponsor
- Vastra Gotaland Region
Dysphagia, Children
Effectivity of TongueFit, A Novel Orofacial Manometer, as Tongue Strength and Endurance Therapy in Children With Dysphagia
The tongue plays a crucial role in the swallowing process, and weakness in its muscles can lead to difficulties in bolus control, mastication, bolus transport, and oral residue.
- Trial name
- NCT06921161
- Testing
- TongueFit, OSMS
- Where
- Indonesia
- Volunteers
- 20 people
- Sponsor
- Rizky Kusuma Wardhani
Appendicitis Acute, Postoperative Sore Throat, Cough, Hoarseness
Effect of Endotracheal Tube Cuff Pressure Management on Postoperative Sore Throat in Pediatric Laparoscopic Appendectomy
Abstract Objective: The aim of this study is to compare two different ways of adjusting the air-filled cushion (cuff) of the breathing tube used during general anesthesia in children undergoing laparoscopic appendectomy (closed…
- Conditions
- Appendicitis Acute, Postoperative Sore Throat, Cough, Hoarseness, Airway Complications, Respiratory Complications
- Trial name
- NCT07678086
- Testing
- Pressure Transducer, Traditional Palpation Method
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Nasopharyngeal Carcinoma
Molecular Genetics Study of Nasopharyngeal Carcinoma: Characterization of NCP Susceptibility Gene(s)
The objective of this study is to characterize genes associated either with susceptibility or resistance to the development nasopharyngeal carcinoma (NPC) in a Chinese population where the incidence of NPC is as high as 50 in…
- Trial name
- NCT00341146
- Where
- China
- Volunteers
- 6,490 people
- Sponsor
- National Cancer Institute (NCI)
Streptococcal Sore Throat
In Vitro Diagnostic Device for the Detection of Strep A
The purpose of this trial is to show the accuracy and specificity of the Liat analyzer and assay for detecting Strep A at the point of care lab compared to culture.
- Trial name
- NCT02068469
- Where
- 5 sites in United States
- Volunteers
- 799 people
- Sponsor
- IQuum, Inc.
Nasopharyngeal Carcinoma
LMP1- and LMP2-Specific CTLs to Patients With EBV-Positive NPC (NATELLA)
Patients have a type of cancer called nasopharyngeal carcinoma (NPC) which has either come back, not gone away or is at high risk for coming back after the best treatment we know for this disease.
- Trial name
- NATELLA (NCT00516087)
- Testing
- Genetically modified CTLs
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Baylor College of Medicine
Dysphagia, Swallowing Disorders
taVNS in Infants Severe Dysphagia
This study evaluates the safety, feasibility, and preliminary effects of transcutaneous auricular vagus nerve stimulation (taVNS) paired with an oral sensorimotor training protocol in infants with severe dysphagia.
- Conditions
- Dysphagia, Swallowing Disorders, Feeding and Eating Disorders of Infancy
- Trial name
- NCT07802301
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS), Oral Sensorimotor Training Protocol
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Medical University of South Carolina
Otorhinolaryngologic Disease, Otorhinolaryngologic Neoplasm
Ultrasound Evaluation of Tongue Movements in Speech and Swallowing
This study will assess the use of ultrasound-a test that uses sound waves to produce images-as a diagnostic tool for evaluating speech and swallowing.
- Conditions
- Otorhinolaryngologic Disease, Otorhinolaryngologic Neoplasm, Pharyngeal Neoplasm, Polymyositis
- Trial name
- NCT00001167
- Where
- United States
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Chronic Diarrhea, Persistent Vomitting
Pediatric GI Endoscopy at Assiut University
1. To evaluate the diagnostic role, and outcomes of upper and lower gastrointestinal (GI) endoscopy in identifying gastrointestinal disorders among infants and pediatric patients attending Assiut University Children Hospital. 2.
- Conditions
- Chronic Diarrhea, Persistent Vomitting, Gastrointestinal Bleeding, Dysphagia
- Trial name
- NCT07239934
- Testing
- Gastrointestinal Endoscopy
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Assiut University
Tonsillitis
Tonsillectomy in Recurrent Tonsillitis
The purpose of this study is to determine whether tonsillectomy is effective in preventing further streptococcal pharyngitis episodes in patients with recurrent tonsillitis.
- Trial name
- NCT00136877
- Testing
- (adeno)tonsillectomy
- Where
- Finland
- Volunteers
- 70 people
- Sponsor
- Oulu University Hospital
Abscess, Peritonsillar
Impact of Anti-inflammatory and Antibiotic Therapy on the Emergence of Peri-tonsillar Abscess
Analyze in children and adults, risk factors in the onset of the APA. The main hypothesis focuses on the use of anti-inflammatory in the context of pharyngitis or sore throat before the symptoms of ABS. Secondary objectives: 1.
- Trial name
- APA (NCT00954031)
- Where
- 15 sites in France
- Volunteers
- 711 people
- Sponsor
- Nantes University Hospital
ClassII Division 1 Malocclusion, Mandibular Retrognathism
Effects of Orthopedic Mandibular Advancement in Class II Division 1 Malocclusion on Pharyngeal Airway
This study aims at evaluating the effects of mandibular advancement on pharyngeal airway space and nocturnal breathing in children with skeletal class II division1 malocclusion.
- Trial name
- NCT04255511
- Testing
- Twin Block, Fixed orthodontic appliance
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Otitis Media, Otitis Media With Effusion
Study of Streptococcus Pneumoniae in Nose and Throats of Infants With Acute Otitis Media
The aim of this study is to assess in France the impact of Prevenar on the possible evolution of the pneumococcal serotypes distribution and antibiotic resistance in NP samples of children with AOM.
- Conditions
- Otitis Media, Otitis Media With Effusion, Pneumococcal Infections
- Trial name
- NCT00195611
- Testing
- Prevenar
- Where
- 35 sites in France
- Volunteers
- 3,293 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Endocrine; Deficiency, Hypothalamo-Pituitary Disorder
Brain Irradiation for Childhood Cancer - Endocrine Monitoring During the First Years
BICHE- 1: Brain Irradiation for Childhood cancer - Endocrine monitoring during the first five years is a study of endocrine monitoring after cerebral radiotherapy.
- Conditions
- Endocrine; Deficiency, Hypothalamo-Pituitary Disorder, Radiotherapy Side Effect
- Trial name
- BIChE-1 (NCT06618703)
- Testing
- Blood sample, urine sample, osteodensitometry
- Where
- 3 sites in France
- Volunteers
- 230 people
- Sponsor
- University Hospital, Angers
Group A Streptococcal Pharyngitis
Group A Pharyngitis in Children: The GASPARD Study
Evaluate the necessity to treat with antibiotics GAS pharyngitis in children in Switzerland. The null hypothesis is that antibiotic treatment is not necessary for GAS pharyngitis in this population.
- Trial name
- GASPARD (NCT03264911)
- Where
- Switzerland
- Volunteers
- 360 people
- Sponsor
- Klara Posfay-Barbe
Sore Throat, Pharyngitis
APC-111 MP Tablet Once a Day vs.Penicillin VK Four Times a Day Both for 10 Days in Patients With Strep Throat
The primary objective of this study is to evaluate the efficacy of APC 111 MP Tablet, 775 mg tablet, given orally (PO)once daily (QD) for 10 days compared to that of Penicillin VK, 250 mg PO four times daily (QID) for 10 days in…
- Conditions
- Sore Throat, Pharyngitis, Tonsillitis
- Trial name
- NCT00242281
- Testing
- APC-111 MP Tablet, 775 mg
- Where
- 41 sites in United States, Canada
- Volunteers
- 600 people
- Sponsor
- Advancis Pharmaceutical Corporation
Chronic Tonsillitis
HPV Prevalence in the Mouth and Oropharynx of the Tonsillectomy Population
The principal aim of this study is to provide vital current data on the prevalence, distribution and natural history of Human Papilloma Virus (HPV) infection in the mouth.
- Trial name
- Oromouth (NCT01330147)
- Where
- 8 sites in United Kingdom
- Volunteers
- 937 people
- Sponsor
- University of Birmingham
Preterm Infant, Feeding Disorder Neonatal
Oropharyngeal Administration of Mother's Milk in Preterm Infants and Gastrointestinal Motility
Mother's milk does not come in contact with the oropharyngeal pouch of preterm infants during gavage feeding. We hypothesized that stimulation of the oropharyngeal pouch using small amount of the mother's milk 5 minutes before…
- Conditions
- Preterm Infant, Feeding Disorder Neonatal, Gastrointestinal Motility Disorder
- Trial name
- OPAMM (NCT03552510)
- Testing
- Oro-pharyngeal Administration of Mother's Milk
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University Children Hospital