Clinical trials: Physical Function
Cerebral Palsy
Gross Motor Function and Living Skills in CP
Cerebral palsy (CP) is non-progressive disorder, which undergoes mishap to the developing brain and it affects a person's ability to move and maintain balance and posture.
- Trial name
- NCT06460779
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Riphah International University
Schizophrenia
Oculomotor and Spatial Cognition Deficits in Schizophrenia
DESCRIPTION: (Verbatim from the Applicant's Abstract) Abnormalities of eye movement control and spatial cognition are well-established deficits in schizophrenia.
- Trial name
- NCT00931996
- Testing
- Antipsychotic
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Pneumonia
Effect of Pursed-Lip Breathing on Physiological Parameters and Discharge Readiness in Children With Pneumonia
This study aims to evaluate the effects of Pursed-Lip Breathing (PLB) exercises on physiological parameters (such as respiratory rate, heart rate, and oxygen saturation) and discharge readiness in children diagnosed with…
- Trial name
- PLB-PEDPNEU (NCT07106203)
- Testing
- Pursed-Lip Breathing (PLB)
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Ataturk University
Diabetes Mellitus
Preservation of Pancreatic Beta Cell Function Through Insulin Pump Therapy
Type I diabetes (T1DM) is the second most common chronic illness effecting children in the USA. Worldwide, Type I diabetes is increasing in incidence, and its underlying etiology remains elusive.
- Trial name
- ktpump (NCT00574405)
- Testing
- MDI (split-mix NPH insulin + regular insulin or Lantus + Novolog® [or Humalog®]), CSII (Animas Corporation insulin pump, model IR 1200)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Arkansas Children's Hospital Research Institute
Turner Syndrome
The Effect of Androgen and Growth Hormone on Height and Learning in Girls With Turner Syndrome
The purposes of this study are to learn whether treatment with an androgen type hormone will improve the visual-spatial problems associated with Turner syndrome, and to evaluate the effect growth hormone, with and without…
- Trial name
- NCT00029159
- Testing
- estrogen, androgen
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Thomas Jefferson University
Dermatitis Atopic
Dupilumab-PEdiatric Skin Barrier Function and LIpidomics STudy in Patients With Atopic Dermatitis
Primary Objective: Evaluate changes in skin barrier function with transepidermal water loss (TEWL) assessed after skin tape stripping (STS) in predefined lesional skin in pediatric participants with moderate to severe atopic…
- Trial name
- PELISTAD (NCT04718870)
- Testing
- Dupilumab SAR231893
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Sanofi
Schizophrenia
Effects of Buspirone Combined With Clozapine
This study aimed to evaluate the enhancing effects of different doses of buspirone on psychiatric symptoms and cognitive function in patients with schizophrenia.
- Trial name
- NCT06906224
- Testing
- Low-dose group (buspirone tablets, clozapine), High-dose group (buspirone tablets, clozapine)
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Chuanfu Song
End Stage Kidney Disease, Delayed Graft Function
Better Evidence for Selecting Transplant Fluids
End-stage kidney disease (ESKD) is a significant, expensive health problem. Kidney transplantation improves survival, quality of life, and is much cheaper than dialysis treatment for ESKD.
- Conditions
- End Stage Kidney Disease, Delayed Graft Function, Kidney Transplant; Complications
- Trial name
- BEST-Fluids (NCT03829488)
- Testing
- Plasma-Lyte 148 (approx. pH 7.4) IV Infusion, 0.9% SODIUM CHLORIDE 9g/L injection BP
- Where
- 18 sites in Australia, New Zealand
- Volunteers
- 808 people
- Sponsor
- The University of Queensland
Cerebral Palsy
Assessment of Trunk Position Sense, Trunk Control, and Functional Independence in Children With Cerebral Palsy
The purpose of this study is to determine whether there is a difference in trunk proprioception, as assessed by trunk position sense, in children with unilateral and bilateral spastic cerebral palsy, and to evaluate the…
- Trial name
- NCT07347483
- Testing
- Only measurements were taken.
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Cumhuriyet University
Prostate Cancer
Early Assessment of Treatment Response Using Functional Diffusion Mapping
This study will evaluate the feasibility of identifying changes in diffusion MRI characteristics of bone that correlates with response to therapy in men with metastatic prostate cancer.
- Trial name
- NCT02064283
- Testing
- Diffusion MRI
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Michigan Rogel Cancer Center
Cerebral Palsy, Hypertonia
Impact of Listening to Low Tones on Motor Function in Children With CP
The study aims to evaluate the impact of a possible new treatment for hypertonia, contributing to the motor disability in children with cerebral palsy (CP).
- Trial name
- NCT00394641
- Testing
- listening to music / stories via stereophonic headphones
- Where
- Israel
- Volunteers
- 22 people
- Sponsor
- Shaare Zedek Medical Center
Sports Physical Therapy
Effects of Speed Endurance Training on Agility and Functional Performance in Soccer Players
Ethical approval is taken from ethical committee of Riphah International university Randomized Control Trial (RCT) will be conducted at Pakistan Cricket Board (PCB) Lahore, through convenience sampling technique on 44 athletes of…
- Trial name
- NCT06131073
- Testing
- speed endurance production (SEP) training along with conventional training., conventional training
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Healthy Preschoolers
Fundamental Movement Skills Training Improves Executive Functions in Preschoolers
This randomized controlled trial investigated the effects of a 12-week structured fundamental movement skills (FMS) training program on executive functions in 34 healthy preschoolers aged 5-6 years.
- Trial name
- FMS-EF-RCT (NCT07725354)
- Testing
- Fundamental Movement Skills Training, Regular Physical Activity
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Xi'an Physical Education University
Mullerian Anomaly of Vagina, Mullerian Anomaly of Uterus, Nec
Diagnostic, Therapeutic and Reproductive Aspects of Patients With Mullerian Anomalies (MULAN)
The purpose of this study is to get a better understanding of the clinical implications (including reproductive problems and obstetric complications), appropriate diagnostic tools and correct surgical treatment of Mullerian…
- Conditions
- Mullerian Anomaly of Vagina, Mullerian Anomaly of Uterus, Nec, Mullerian Anomaly of Cervix
- Trial name
- MULAN (NCT04732546)
- Where
- Belgium
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Ghent
Pulmonary Function
Service and Health Among Deployed Veterans
The purpose of the study is to better understand the health, including lung health, of Veterans who deployed in support of Operation Enduring Freedom (OEF), Operation Iraqi Freedom (OIF), or Operation New Dawn (OND) and other…
- Trial name
- SHADE (NCT02825654)
- Where
- 6 sites in United States
- Volunteers
- 6,200 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Traumatic Brain Injury
Virtual Reality in Rehabilitation of Executive Functions in Children With Mild or Moderate Traumatic Brain Injury
Traumatic brain injury (TBI) causes lifelong disability. Children with TBI often have difficulties in attention regulation and executive functions affecting their daily living.
- Trial name
- VREALFUN-TBI (NCT06127459)
- Testing
- Parental Guidance, Virtual Reality Game
- Where
- Finland
- Volunteers
- 44 people
- Sponsor
- Merja Nikula
Cognitive Function
Cognition Intervention Study Dortmund- Continued (Coco)
The Cognition Intervention Study Dortmund (CogniDo) and the Cognition Intervention Study Dortmund PLUS (CogniDo PLUS) investigated the short-term effects of having school lunch versus skipping it on children's basal (CogniDo) and…
- Trial name
- Coco (NCT02344056)
- Testing
- Having lunch/skipping lunch, Skipping lunch/having lunch
- Where
- Germany
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Research Institute of Child Nutrition, Dortmund
Neuromuscular Diseases
Bulbar Function in Neuromuscular Patients
The main objective is prospectively study the upper airways function in an adult population of neuromuscular patients. The main measurement will be the evolution of tongue strength recorded each year during annual clinical…
- Trial name
- ORDEG (NCT02097368)
- Testing
- tongue strength measurement, respiratory function measurement, swallowing tests
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Congenital Heart Defects
Using Tissue Doppler/Synchronization to Determine Heart Function in Children With Congenital Heart Disease
There are many children that have heart dysfunction because they are either born with Congenital Heart Disease (CHD) or developed poor heart function because their hearts are ill.
- Trial name
- NCT00208676
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Emory University
Duchenne Muscular Dystrophy With Mutations Amenable to PBGENE-DMD
PBGENE-DMD Phase 1/2a Safety and Preliminary Efficacy Study in Duchenne Muscular Dystrophy (FUNCTION-DMD)
The purpose of this Phase 1/2a trial is to evaluate the safety, tolerability, and preliminary efficacy of PBGENE-DMD in patients with DMD harboring mutations amenable to excision of exons 45-55.
- Trial name
- NCT07429240
- Testing
- PBGENE-DMD (IV)
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Precision BioSciences, Inc.
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