Clinical trials: Physical Function
Achilles Tendon Rupture
Impact of Achilles Tendon Rupture on the Achilles Tendon and Calf Muscles
The aim of this study is to measure the recovery following Achilles tendon rupture. The investigators will use an ultrasound scan to look at the Achilles tendon, they will complete calf strength tests and use questionnaires to…
- Trial name
- ARCH (NCT05683080)
- Testing
- Routine Clinical Care
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Leicester
Bladder Function
Unilateral Cutaneous Ureterostomy - Long Term Follow up
This observational study is aimed at exploring bladder function following temporary unilateral low loop cutaneous ureterostomy carried out in newborns suffering from severe congenital hydro-ureteronephrosis
- Trial name
- ureterostomy (NCT00546208)
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Sheba Medical Center
Renal Injury
Impact of in Utero and Breastfeeding Exposure to Tenofovir on Renal Function in HIV-exposed Uninfected Children
The goal of this project is to determine whether and how in utero exposure to Tenofovir affects renal function in HIV-exposed uninfected infants
- Trial name
- NCT04070482
- Testing
- Tenofovir exposure in utero and during breastfeeding
- Where
- 3 sites in Cameroon
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Yaounde 1
Premature Baby, Pulmonary Hypertension of Newborn
Measuring Heart Health in Both Term, Preterm and Unwell Newborn Babies With an Advanced Ultrasound Method: Speckle Tracking Echocardiography
This study aims to improve how neonatologists check the heart function of newborn babies, especially those who are sick. While standard heart ultrasound scans are useful, a more advanced and sensitive technique called 2D speckle…
- Conditions
- Premature Baby, Pulmonary Hypertension of Newborn, Hypoxic Ischaemic Encephalopathy (HIE), Congenital Diaphragmatic Hernia
- Trial name
- NCT07364682
- Where
- United Kingdom
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Birmingham Women's NHS Foundation Trust
Friedreich Ataxia
Efficacy of Stabilometric Platform to Improve Standing Balance in Patients With Friedreich's Ataxia
The primary objective is to evaluate the potential effectiveness of an individualized intensive rehabilitation intervention using the "Prokin 252" stabilometric platform in the treatment of adolescent and adult patients with…
- Trial name
- NCT06692296
- Testing
- Balance training over stabilometric platform, Balance training by means of conventional rehabilitation
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- IRCCS Eugenio Medea
Salt; Deficit (or Low), Cystic Fibrosis
Evaluation of Salt Status in Patients With Cystic Fibrosis
The results of the annual check-up will be collected to evaluate the best urinary marker for fractional sodium excretion and salt status will be correlated to clinical outcome measures.
- Trial name
- NCT04556162
- Testing
- fractional sodium excretion, risk subgroups
- Where
- Belgium
- Volunteers
- 222 people
- Sponsor
- University Hospital, Ghent
Magnetic Resonance Imaging, Ovarian Function
Fertility After Transvaginal Surgery or Uterine Artery Embolization Combined With Uterine Curettage in Patients With Cesarean Scar Pregnancy
To investigate the fertility in patients after treatment by transvaginal surgery or uterine artery embolization combined with uterine curettage
- Conditions
- Magnetic Resonance Imaging, Ovarian Function, Menstruation
- Trial name
- NCT02933190
- Testing
- transvaginal surgery；UAE and D&C
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Hamstring Flexibility, Hamstring Muscle Tightness
Effects of Combining PNF With NMES in Young Football Players
Hamstring muscle injuries are common in sports like football and often lead to extended periods of inactivity. This study aims to compare the effects of two different stretching programs on hamstring flexibility, with a secondary…
- Trial name
- PNF+NMES (NCT07075497)
- Testing
- Neuromuscular electrical stimulation (NMES), Contract-Relax PNF (crPNF)
- Where
- Spain
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Diabetes Mellitus, Type 1
Influence of Vitamin D on Vascular Function in Adolescents and Young Adults With Type 1 Diabetes
The purpose of this study is to study the role of low vitamin D levels on the health of blood vessels or vascular function in adolescents and young adults with type 1 diabetes.
- Trial name
- NCT01103817
- Testing
- Vitamin D
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- The Hospital for Sick Children
Diabetes Mellitus, Type 1
A Research Trial of Aralast in New Onset Diabetes (RETAIN)
The drug Alpha-1 Antitrypsin (AAT, Aralast NP) is being tested in this study as an anti-inflammatory drug (a medication that decreases inflammation, which is part of the body's normal ability to fight infection and respond to…
- Trial name
- RETAIN (NCT01183468)
- Testing
- Aralast NP 45 mg dose, Aralast NP 90 mg dose, Aralast NP 180 mg dose
- Where
- 15 sites in United States
- Volunteers
- 17 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cerebral Palsy
Functional Electrical Stimulation (FES) for Upper Extremity Hemiplegia in Children With Cerebral Palsy
The proposed pilot study seeks to explore the effectiveness of Functional Electrical Stimulation (FES) to improve upper limb function in children and youth (aged 6 to 18 years) with hemiplegic cerebral palsy, as measured by the…
- Trial name
- NCT03016923
- Testing
- FES Therapy
- Volunteers
- 3 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Depression
Neural Mechanisms of Temporal Interference Stimulation on Improving Social Reward Function in Depression
Major depressive disorder (MDD) is a mood disorder characterized primarily by low mood, diminished interest, and reduced energy.
- Trial name
- NCT07287878
- Testing
- Temporal Interference Simulation(TIS), Temporal Interference Stimulation(TIS)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Mild Traumatic Brain Injury, Concussion, Mild
Exercise as Concussion Therapy Trial- 2
This study is a Phase 2, open-label study of a therapeutic intervention (graded exercise)compared to a reference therapy (passive stretching) in patients who have sustained mTBI.
- Trial name
- ExACTT (NCT04578743)
- Testing
- Graded Exercise Therapy: ClearPlay(TM)
- Where
- 3 sites in Australia
- Volunteers
- healthy volunteers welcome
- Sponsor
- ANSwers Neuroscience, Inc.
Cerebral Palsy (CP), Hemiparetic Cerebral Palsy
Robot-Assisted Mirror Therapy in the Rehabilitation of Hemiparetic Cerebral Palsy
The goal of this clinical trial is to learn whether robot-assisted mirror therapy improves upper extremity function in children with spastic hemiparetic cerebral palsy.
- Trial name
- NCT07763691
- Testing
- Robot-Assisted Mirror Therapy, Mirror Therapy, Neurodevelopmental Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Medipol University
Obesity, Childhood
Healthy Bodies Project to Prevent Childhood Obesity
The goal of this study is to evaluate components of a preschool-based intervention designed to (1) increase children's nutrition knowledge, (2) increase physical activity in childcare settings, (3) increase emotional, behavioral…
- Trial name
- Healthy Bodies (NCT04552678)
- Testing
- Healthy Eating, Active Play, Self-Regulation, Parent Education, Healthy Eating, Active Play, Self-Regulation, Healthy Eating, Active Play, Parent Education
- Volunteers
- 2,480 people, healthy volunteers welcome
- Sponsor
- Penn State University
Gastroschisis
Evaluation of Glycerin Suppositories to Improve Bowel Function in Gastroschisis
Gastroschisis is a congenital defect of the abdominal wall that leads to evisceration of various amounts of the abdominal organs.
- Trial name
- NCT03355326
- Testing
- Glycerin Suppository
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Indiana University
Upper Extremity Function In Childern With Erb's Palsy
Effect of Action Observation Therapy Versus Kinesio Taping on Upper Extremity Function In Children With Erb' Palsy
The purpose of this study is to study the Effect of Action Observation Therapy versus Kinesiology Taping on upper extremity function In Erb\'s Palsy Children.
- Trial name
- NCT06930040
- Testing
- Action observation therapy protocol, Kenisiotaping
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Kafrelsheikh University
Somatic Symptom Disorder
Alexithymia and Attachment Style in Patients With Somatic Symptoms
To evaluate whether emotional awareness, attachment style and the ability to abstract and symbolize (IQ) influence the appearance of somatic symptoms.
- Trial name
- NCT05666921
- Testing
- psychological assessment
- Where
- 2 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Meyer Children's Hospital IRCCS
Cerebral Palsy, Rehabilitation
The Effect of Tactile Deficit on Motor Function in Unilateral Cerebral Palsy
Cerebral palsy(CP) is the most common cause of disability in childhood. The motor spectrum of disorders is characterized by abnormal muscle tone, posture, and movement.
- Conditions
- Cerebral Palsy, Rehabilitation, Tactile Perception
- Trial name
- NCT05013814
- Testing
- Semmes-Weinstein monofilament test, Box and Block Test, 9-Hole Peg Test
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Marmara University
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