Clinical trials: Physical Function
End-Stage Renal Disease
Effect of Different Hemodialysis Modality on Adiponectin,Vascular Function and Clinical Prognosis
Adiponectin, an adipose tissue derived protein, with anti-inflammatory properties that is secreted from adipose tissue, is associated with insulin resistance.
- Trial name
- NCT00155363
- Testing
- conventional artificial kidney (AK) vs. high flux AK
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Glomerulopathy, C3G
Pilot STUDY to Monitor Ex-vivo the Biological Effects of the C3 Inhibitor, PEGCETACOPLAN, on Activation of Complement in Fluid Phase and on Podocytes in Patients With C3G and Primary IC-MPGN
This is a prospective, multicenter, non-interventional, observational pharmacological real-world study to characterize longitudinal changes in ex vivo biomarkers of complement activation in patients with C3G and primary IC-MPGN…
- Conditions
- Glomerulopathy, C3G, Membranoproliferative Glomerulonephritis (MPGN)
- Trial name
- COMPASS (NCT07904338)
- Testing
- Blood sample
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
Injury, Brain
Use of the LOK® Robotic Gait Trainer in the Early Rehabilitation of Children After an Acquired Brain Injury (ABI)
After an acquired brain injury (ABI), children often require extensive physiotherapy (PT) to help them relearn to walk. There is promising evidence in pediatric neuro-motor conditions of the possibility for brain activation…
- Trial name
- NCT03678064
- Testing
- Lokomat
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Hyperoxia
Hyperoxygenation in Anesthetized Children
This study is aiming at assessing the effect of inspired oxygen fraction during general anesthesia on children's lung mechanics and volume.
- Trial name
- OXPED (NCT02384616)
- Testing
- Oxygen
- Where
- Switzerland
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Walid HABRE
Obesity, Liver Function
Obesity and Liver Function in Oesophageal Cancer
There is an established link between sarcopenia and outcomes in oesophageal cancer. There is scant reports in the literature regarding the influences of different obesity in different compartments.
- Trial name
- NCT04152044
- Testing
- Observation of different types of obesity and liver pathology in patients undergoing and oesophagectomy
- Where
- Ireland
- Volunteers
- 658 people, healthy volunteers welcome
- Sponsor
- St. James's Hospital, Ireland
Adolescent Idiopathic Scoliosis
MESA Rail™ AIS Study - Preservation of Curve Correction
To evaluate the restoration and maintenance of thoracic kyphosis and coronal curve correction demonstrated through the surgical implantation of the K2M MESA Rail™ Deformity System as compared to literature reported outcomes for…
- Trial name
- NCT02062606
- Testing
- MESA Rail™ Deformity System
- Volunteers
- 188 people
- Sponsor
- K2M, Inc.
Brain Injuries, Traumatic, Concussion, Brain
Objective Brain Function Assessment of mTBI/Concussion in High School Athletes
This study (Part 2) is designed to build a database including EEG, neurocognitive performance, clinical symptoms, history and other relevant data, which will be used to derive a multimodal EEG based algorithm for the…
- Conditions
- Brain Injuries, Traumatic, Concussion, Brain, Concussion, Mild, Concussion, Intermediate
- Trial name
- AheadCAS-HS (NCT02661633)
- Testing
- BrainScope Ahead 200iD, Advanced MRI Neuroimaging
- Where
- 4 sites in United States
- Volunteers
- 177 people
- Sponsor
- BrainScope Company, Inc.
Physical Activity, Children
Effectiveness of MOVI Interventions on Adiposity, Cognition and Motor Competence: MOVI-da10!
Project which objective is to test the effectiveness of a classroom-based physical activity intervention (MOVI-da10!) on improving, body composition, cardio-respiratory fitness and executive function.
- Conditions
- Physical Activity, Children, Obesity, Cardiovascular
- Trial name
- MOVI-da10! (NCT03236363)
- Testing
- MOVI-da10! active breaks, MOVI-da10! integrated physical activity
- Where
- Spain
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Type1 Diabetes Mellitus, Diabetes Mellitus, Type 1
MEtabolic and Renal Effects of AutoMAted Insulin Delivery Systems in Youth With Type 1 Diabetes Mellitus
In type 1 diabetes (T1DM), automated insulin delivery (AID) systems such as the hybrid closed loop artificial pancreas (HCL AP) combine the use of an insulin pump, continuous blood sugar monitor, and control algorithm to adjust…
- Conditions
- Type1 Diabetes Mellitus, Diabetes Mellitus, Type 1, Autoimmune Diabetes, Juvenile Diabetes
- Trial name
- MERMAID-T1D (NCT03945747)
- Testing
- Blood draw, Urine sample collection, DXA scan
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Anterior MI, Colchicine
Effect of Colchicine On Left Ventricle Function After Anterior Myocardial Infarction Assessed By Speckle Tracking
Effect of colchicine use on Left ventricles systolic function in patients with anterior S-T elevation myocardial infarction undergoing primary Percutaneous coronary intervention by using speckle tracking Echocardiography…
- Trial name
- NCT05200052
- Testing
- Colchicine 0.5 mg Oral Tablet
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pediatric Cancer, Inspiratory Muscle Training
The Effect of Inspiratory Muscle Training on Pediatric Cancer Patient
The aim of this study is to examine the effects of inspiratory muscle training on respiratory functions, functional capacity, fatigue and quality of life in pediatric cancer patients who have recently completed treatment.
- Trial name
- NCT06597552
- Testing
- Training Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 8 people
- Sponsor
- Medipol University
Pro-opiomelanocortin (POMC) Deficiency Obesity
Setmelanotide for the Treatment of Early-Onset Pro-Opiomelanocortin (POMC) Deficiency Obesity
To demonstrate statistically significant and clinically meaningful effects of setmelanotide on percent body weight change in participants with pro-opiomelanocortin (POMC) deficiency or proprotein convertase subtilisin/kexin type…
- Trial name
- NCT02896192
- Testing
- Setmelanotide
- Where
- 7 sites in United States, Belgium and 5 more
- Volunteers
- 15 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Cardiomyopathy, Dilated
Vitamin D Supplementation Can Improve Heart Function in Idiopathic Cardiomyopathy
Vitamin D deficiency could be a high risk for cardiovascular diseases. It has been recently reported that vitamin D deficiency is another cause of heart failure and cardiomyopathies.
- Trial name
- NCT02517814
- Testing
- Vitamin D
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hillel Yaffe Medical Center
Brain Structural Connectivity, Cognitive Function
Developmental Trajectory of Brain Structural Connectivity and Cognitive Function From Childhood to Adulthood
Magnetic resonance imaging (MRI) is a premier modality to investigate structures and functions of human brain. In studies of children and adolescents, noninvasiveness of MRI makes it especially applicable.
- Trial name
- NCT01677793
- Where
- Taiwan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Hidradenitis Suppurativa, Wide Excision
Quality of Life After Wide Surgical Excision in Patients With Hidradenitis Suppurativa
Patients undergoing wide surgical excision of their hidradenitis suppurativa areas are asked by telephone about their quality of life by standard questionnaires (WHOQOL-BREF, DLQI, Skindex, MHF, FLQA-d) and their sexual function…
- Trial name
- NCT02593604
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University Hospital Schleswig-Holstein
E Cigarette Use
A Behavioral Circuit Breathing Training Intervention on Smoking Cessation and Respiratory Function Among Youth Who Use E-cigarettes
This study aims to evaluate the effects of a six-week behavioral circuit breathing training intervention on smoking cessation and respiratory function compared with diaphragmatic breathing training and usual daily activities
- Trial name
- NCT07882407
- Testing
- Circuit Breathing Intervention, Diaphragmatic Breathing
- Where
- Thailand
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Muscular Dystrophy, Duchenne, Ambulatory Care
Phase III Study of Idebenone in Duchenne Muscular Dystrophy (DMD)
The aim of this Phase III study was to assess the efficacy of idebenone on pulmonary function, motor function, muscle strength and quality of life in patients with DMD.
- Trial name
- DELOS (NCT01027884)
- Testing
- Idebenone
- Where
- 23 sites in United States, Austria and 8 more
- Volunteers
- 65 people
- Sponsor
- Santhera Pharmaceuticals
Childhood Asthma
More Relaxation by Deep Breath on Methacholine
Deep inhalation (DI) dilates normal airway precontracted with methacholine. The fact that this effect is diminished or absent in asthma could be explained by the presence of bronchial inflammation.
- Trial name
- SouProvocBro (NCT03696602)
- Testing
- bronchial provocation test
- Volunteers
- 78 people
- Sponsor
- Central Hospital, Nancy, France
Multiple Sclerosis, Respiratory; Disorder, Functional, Impaired
Respiratory Function and Walking Capacity in Multiple Sclerosis
Multiple sclerosis (MS) is a chronic progressive neurological disease. Respiratory dysfunction due to weakness in the respiratory musculature has been described in MS.
- Conditions
- Multiple Sclerosis, Respiratory; Disorder, Functional, Impaired, Difficulty Walking
- Trial name
- NCT01774201
- Testing
- Breathing exercises
- Volunteers
- 50 people
- Sponsor
- Region Örebro County
Obstetric; Injury
Modified Constraint Induced Movement Therapy in Children With Obstetric Brachial Plexus Injury
The aim of this study was to increase and improve the use of affected extremity in obstetric brachial plexus palsy children while restricting the use of less affected arm and the purpose was to improve the function, Range of…
- Trial name
- NCT05411731
- Testing
- Conventional physical therapy treatment, Constraint induced movement therapy
- Where
- Pakistan
- Volunteers
- 16 people
- Sponsor
- Riphah International University
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