Clinical trials: Physical Functioning
Chronic Granulomatous Disease (CGD), X-Linked Severe Combined Immune Deficiency (XSCID)
Evaluation of Patients With Immune Function Abnormalities
This study will evaluate patients with abnormal immune function that results in recurrent or unusual infections or chronic inflammation.
- Conditions
- Chronic Granulomatous Disease (CGD), X-Linked Severe Combined Immune Deficiency (XSCID), Leukocyte Adhesion Deficiency 1 (LAD), Graft Versus Host Disease (cGvHD)
- Trial name
- NCT00128973
- Where
- United States
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Fatigue, Joint Hypermobility Syndrome
Functional and Performance Determinants in Climbers: Examining the Role of Mobility, Stability, and Fatigue Across Proficiency Levels
The primary objective is to understand how motor skills and fatigue affect climbing performance in indoor and outdoor climbers, also comparing elite and amateur climbers.
- Conditions
- Fatigue, Joint Hypermobility Syndrome, Climbing Injuries, Cognitive Fatigue
- Trial name
- NCT06830655
- Testing
- Fatigue Protocol
- Where
- 2 sites in Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Disability Physical, Psychological Adaptation
Long Term Clinical and Functional Outcome in Rotationplasty Patients
Rotationplasty is a very special surgical technique. In its most frequent variant it allows, in the bone sarcomas of the distal femur, to remove all the thigh tissues including the knee joint keeping intact the innervation of the…
- Trial name
- GIROMEETING (NCT03385694)
- Testing
- Assessment
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto Ortopedico Rizzoli
Obesity
Effects of Exercise on Arterial Function and Insulin Resistance Syndrome in Pre-pubertal Obese Children
The main purpose of this project is to investigate the effects of an exercise program on arterial function and cardiovascular diseases risk factors in obese and lean pre-pubertal children.
- Trial name
- NCT00801645
- Testing
- Exercise
- Where
- Switzerland
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Achondroplasia
Prospective Clinical Assessment Study in Children With Achondroplasia (ACH)
This is a long-term, multi-center, observational study in children 2.5 to <17 years with achondroplasia (ACH). The objective is to evaluate growth, ACH-related medical complications, assessments of health-related quality of life…
- Trial name
- NCT04035811
- Where
- 32 sites in United States, Argentina and 9 more
- Volunteers
- 271 people
- Sponsor
- QED Therapeutics, a BridgeBio company
Bilateral Pleural Effusion
Impact of Large-Volume Pleural Effusions on Heart Function
The physiologic basis for relief from dyspnea after therapeutic thoracentesis remains poorly understood. Improvement of the heart and lung function may contribute to the dyspnea relief.
- Trial name
- TTE (NCT02548221)
- Testing
- transthoracic echocardiogram
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Beijing Chao Yang Hospital
SCD
Effect of Virtual Reality on Pain and Function in Children With Sickle Cell Disease: A Randomized Controlled Trial
Significance or rationale of the study: Virtual reality (VR) is a promising non-pharmacological pain management tool. It enhances motor function by promoting cortical reorganization and neuroplasticity.
- Trial name
- RCT (NCT05952817)
- Testing
- virtual reality
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Afnan Bkri
Neonatal Opiate Withdrawal Syndrome
Eating, Sleeping, Consoling for Neonatal Withdrawal (ESC-NOW): a Function-Based Assessment and Management Approach
The overall objective is to determine if the ESC care approach will reduce the time until infants being managed for NOWS are medically ready for discharge.
- Trial name
- (ESC-NOW) (NCT04057820)
- Testing
- Finnegan Neonatal Abstinence Scoring Tool, Eat, Sleep, Console (ESC) care tool
- Where
- 26 sites in United States
- Volunteers
- 1,305 people
- Sponsor
- Advancing Clinical Trials in Neonatal Opioid Withdrawal (ACT NOW) Program
Bladder Cancer, Quality of Life
Impacts and Testing of the "Multi-domains Active-living Program" in Operable Non-Muscle Invasive Bladder Cancer Patients
Among bladder cancer, the majority of them (70%) are non-muscle-invasive bladder cancer (NMIBC). The survival time is even longer in NMIBC. Patients with NMIBC receive surgery or transurethral resection of bladder tumor (TURBT).
- Trial name
- NCT05739968
- Testing
- Usual care + oncology case manager (OCM) care, Multi-domains Active-living Program (MAP) with e-health enhanced intervention + usual care + oncology case manager (OCM) care
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Children, Only, Vestibular Function
Normative Data of Vestibular and Postural Function in Danish Children
The goal of this age-based cohort study is to provide normative data of vestibular function in the general Danish pediatric population.
- Trial name
- VASIC (NCT06229730)
- Testing
- video Head Impulse Test, Cervical Vestibular Evoked Myogenic Potential, Ocular Vestibular Evoked Myogenic Potential
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Gødstrup Hospital
Multiple Sclerosis
Noninterventional Study Assessing Cognitive Function and Physical Activity in People With Multiple Sclerosis
Study assessing cognitive function and physical activity in people with relapsing remitting multiple sclerosis.
- Trial name
- CogniPlus (NCT01491100)
- Testing
- Interferon beta-1b (Betaseron, BAY86-5046)
- Where
- 17 sites in Albania, Algeria and 15 more
- Volunteers
- 1,085 people
- Sponsor
- Bayer
Intergenerational Relations
The Development of an Intergenerational Movement Program for Grandchildren and Their Grandparents Using Co-creation
The aim of this study is to develop, evaluate and implement an intergenerational physical activity program for grandchildren and their grandparents using co-creation focusing on the promotion of (co-)physical activity as a…
- Trial name
- GRANDPACT (NCT06163638)
- Testing
- GRANDPACT Project
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Ghent
Platelet Function Tests, Thrombin Generation Tests
Point-of-care Assessment of Thrombin Generation and Platelet Function in Children Requiring Cardiopulmonary Bypass
Coagulopathy after cardiopulmonary bypass (CPB) is associated with increased morbidity and mortality. Clot formation and clot stability are important factors in coagulation and hemostasis.
- Conditions
- Platelet Function Tests, Thrombin Generation Tests, Perioperative Coagulopathy
- Trial name
- NCT02833025
- Testing
- Thrombin generation and Platelet Function Testing
- Where
- Canada
- Volunteers
- 130 people
- Sponsor
- The Hospital for Sick Children
Spinal Muscular Atrophy (SMA), Neuromuscular Disease
Ultrasonographic Muscle Assessment and Functional Scales in Spinal Muscular Atrophy
This study aims to investigate the relationship between ultrasonographic muscle thickness measurement and echogenicity assessment with functional scales in children with spinal muscular atrophy (SMA).
- Trial name
- NCT06599606
- Testing
- Ultrasonographic Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Social Media Addiction, Cerebral Palsy
Investigation of the Relationship Between the Use of Social Media and Functional Level in Children With CP
The aim of this study is to examine the relationship between screen usage time and problematic social media use in children with Cerebral Palsy (CP) with motor function, hand function, speech and vision function.
- Trial name
- IRoSMFLCP (NCT05023421)
- Testing
- no intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 158 people
- Sponsor
- Hacettepe University
Sotos Syndrome, Beckwith-Wiedemann Syndrome
Body Perception and Representation in Overgrowth Syndromes, Behavioral Assessment and Neuropsychological Development
Sotos Syndrome (SS) and Beckwith-Wiedemann Syndrome (BWS) are known as overgrowth syndromes as they involve an excessive growth of the whole body or of specific body parts.
- Conditions
- Sotos Syndrome, Beckwith-Wiedemann Syndrome, Overgrowth Syndrome, Body Image
- Trial name
- Body-PROBAND (NCT04993235)
- Testing
- NEPSY-II, CBCL and AQ questionnaires, BUT questionnaire and experimental tasks
- Where
- Italy
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Heart Transplantation, Exercise Capacity
Effect of Physical Training on Oxygen Uptake and Endothelial Function in Heart Transplant Recipients
The purpose of this study is to investigate the effect of physical training on work capacity and vascular function after heart transplantation, cardiac transplant recipients are randomized to 8 weeks of intense physical training…
- Conditions
- Heart Transplantation, Exercise Capacity, Endothelial Function
- Trial name
- NCT01028599
- Testing
- Intensive physical exercise
- Volunteers
- 30 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Exercise, Developmental Dysplasia of the Hip
Physical Therapy Applications on the Hip and Defined Functional Parameters in Children With Developmental Hip Dysplasia
The aim of this study was to investigate the effects of physical therapy and rehabilitation applications on the hip and defined functional parameters in children with developmental hip dysplasia.
- Trial name
- NCT06007833
- Testing
- Physical Therapy and Rehabilitation Modalities, Conventional Group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Inonu University
Asthma
Aerobic Exercise in Children With Moderate and Severe Asthma
Regular aerobic physical activity in short-term moderate asthma and severe: Reduce the levels of inflammatory mediators Improves functional capacity Improves Quality of Life Improved lung function Reduces the sensation of dyspnea…
- Trial name
- AECA (NCT01920529)
- Testing
- aerobic exercise
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Epilepsy, Autism Spectrum Disorder
Biomarkers for Epilepsy Development and the Effect of Physical Exercise in Children With Autism
This study aims to identify novel biomarkers for epilepsy development in children with autism and to evaluate the effects of physical exercise on these biomarkers and clinical outcomes.
- Trial name
- ASD/EP (NCT07373431)
- Testing
- Physical activity program
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Skane