Clinical trials: Physiological Conditions
Pain, Postoperative, Neural Therapy of Huneke
Evaluation of the Neural Therapy Effect on Long Term Postoperative Discomforts in Patients Who Undergo Bilateral Tubal Ligation
The aim of this study was to explore the effect of neural therapy on postoperative pain and discomfort such as abdominal swelling; and gynecologic symptoms such as dysmenorrhea, dyspareunia, amount of menstrual bleeding and…
- Conditions
- Pain, Postoperative, Neural Therapy of Huneke, Dysmenorrhea, Dyspareunia
- Trial name
- NCT03761862
- Testing
- Neural Therapy
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Respiratory Control in Premature Infants
Prematurity-Related Ventilatory Control
The purpose of this research study is to improve our understanding of unstable breathing and heart blood flow patterns seen in premature infants.
- Trial name
- PreVent (NCT03464396)
- Testing
- Bedside Physiology study, Carotid Body Function Test, Room Air Challenge
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- Washington University School of Medicine
Pain, Acute, Newborn; Vitality
The Effect of Heart Sound and White Noise on Pain and Physiological Parameters During Hepatitis B Vaccine Injection
It can cause physiological and behavioral changes in infants such as pain, tachycardia, hypoxemia, increased blood pressure, grimacing, prolonged crying, and irritability.
- Trial name
- NCT06279169
- Testing
- Heart Sound, White Noise
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people
- Sponsor
- Bartın Unıversity
Pain, Sedation
Effect of Maternal Voice on Pain, Sedation, and Physiological Parameters in Mechanically Ventilated Children
Children in the pediatric intensive care unit often experience pain and stress from medical procedures, even while sedated. This study will test whether playing a recording of the child's mother's voice helps reduce pain and the…
- Conditions
- Pain, Sedation, Mechanical Ventilation
- Trial name
- NCT07753486
- Testing
- Recorded Maternal Voice
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- TC Erciyes University
Congenital Heart Disease, Disorder of Fetus or Newborn
Corticosteroid Therapy in Neonates Undergoing Cardiopulmonary Bypass
Although cardiopulmonary bypass (heart-lung machine) is a necessary component of heart surgery, it is not without consequences. Cardiopulmonary bypass initiates a potent inflammatory response secondary to the body's recognition…
- Trial name
- NCT01579513
- Testing
- Methylprednisolone
- Where
- 2 sites in United States
- Volunteers
- 190 people
- Sponsor
- Medical University of South Carolina
Neurofibromatosis Type 1
A Study to Evaluate the Feasibility of a Physiologic Biomarker to Assess Pain and Other Sensory Problems Using Pupillometry in Participants With Neurofibromatosis Type 1 (NF1)
Background: Neurofibromatosis type 1 (NF1) is a genetic condition that causes tumors to grow along the nerves in the skin, brain, and other parts of the body.
- Trial name
- NCT06507748
- Testing
- AlgometRx Nociometer(R)
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- National Cancer Institute (NCI)
Chest Pain, Sickle Cell Anemia
Effects of Nitric Oxide and Nitroglycerin in Patients With Sickle Cell Anemia
Sickle cell anemia is the most common genetic disease affecting African-Americans. About 1 in every 1000 African-Americans has the disease and 1 in every 12 carry the genes that could be passed on to their children.
- Trial name
- NCT00001716
- Testing
- Nitric Oxide, Nitroglycerin
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Feeding Behavior
New Chicco Bottles Study
Breastfeeding is recommended as the ideal form of nutrition for newborns and infants at least for the first 6 months of life by several Institutions such as the American Academy of Pediatrics (AAP) and the World Health…
- Trial name
- Step-Up (NCT03311282)
- Testing
- infants bottles
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Sprim Advanced Life Sciences
Physiological Shock
G- Forces On Retrieved ChildrEn Pilot Study
G-Forces On Retrieved ChildrEn (Pilot) Study is a feasibility study looking at the effect of G-Forces in vivo during episodes of paediatric critical care transport.
- Trial name
- G-FORCE (NCT04586374)
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Apnea of Prematurity, Prematurity
Maternal Odor as a Developmental Care Intervention for Apnea of Prematurity
Apnea of prematurity is one of the most common complications in preterm infants hospitalized in neonatal intensive care units. This randomized controlled trial was conducted to evaluate the effect of maternal odor exposure as a…
- Trial name
- MOCARE (NCT07689669)
- Testing
- Maternal odor
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Yildirim Beyazıt University
Children, Postoperative Pain
Maternal Voice Versus White Noise in Pediatric Surgery
This randomized controlled study will evaluate the effects of maternal voice and white noise on postoperative pain, comfort, and physiological parameters in children aged 1 month to 3 years during the early postoperative period.
- Conditions
- Children, Postoperative Pain, Physiological Parameters, Comfort
- Trial name
- NCT07785297
- Testing
- Maternal Voice Recording, White Noise Recording
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Kocaeli University
Obesity, Adolescent Obesity
Physiologic Response to Bariatric Surgery and the Impact of Adjunct Semaglutide in Adolescents
The study plans to learn more about what happens to the body after bariatric surgery in people 12 to 24 years old. The study aims to understand why people respond differently to bariatric surgery and how to define success beyond…
- Conditions
- Obesity, Adolescent Obesity, Body-Weight Trajectory, Weight Loss Trajectory
- Trial name
- PRESSURE (NCT06575738)
- Testing
- Injectable semaglutide or injectable tirzepatide, Standard postoperative care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Colorado, Denver
Retinopathy of Prematurity
Infant-parent Skin-to-skin Contact During Screening for Retinopathy
Retinopathy of prematurity (ROP) is a feared complication of premature birth. If discovered in time, the disease can be treated, and impaired vision or blindness can be reduced.
- Trial name
- NCT02780544
- Testing
- skin-to-skin contact, incubator, Sucrose
- Where
- Norway
- Volunteers
- 34 people
- Sponsor
- St. Olavs Hospital
Pain, Procedural
The Effect of Local Anesthesia on Control of Intraoperative Physiologic Parameters and Post Operative Comfort
The purpose of this study is to compare patient responses during and after surgery when local anesthetic is used for dental treatment under general anesthesia (GA) and when it is not used.
- Trial name
- NCT04500158
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Virginia Commonwealth University
Sepsis
MEWS, qSOFA and Physiological Parameters Combination in the Emergency Room
In the development of sepsis treatment of recent years, the demand for medical manpower has increased significantly when patients with sepsis appear because of the expansion of medical care demand and shortened response time…
- Trial name
- qSOFA (NCT05584098)
- Testing
- qSOFA, MEWS and physiological parameters combination
- Where
- 2 sites in Taiwan
- Volunteers
- 950 people
- Sponsor
- St. Martin De Porress Hospital
Nonmalignant Neoplasm, Prostate Cancer
Pelvic Floor Muscle Training and Biofeedback or Standard Therapy in Men Who Have Undergone Radical Prostatectomy or Transurethral Resection of the Prostate
RATIONALE: Personalized training by a health professional may improve urinary incontinence. It is not yet known whether pelvic floor muscle training and biofeedback are more effective than standard therapy in improving urinary…
- Conditions
- Nonmalignant Neoplasm, Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment, Sexual Dysfunction
- Trial name
- NCT00632138
- Testing
- exercise intervention, questionnaire administration, biofeedback
- Where
- 37 sites in United Kingdom
- Volunteers
- 800 people
- Sponsor
- Aberdeen Royal Infirmary
Atelectasis, Postoperative, Hypoxia
Physiological Effects and Safety of Continuous High-frequency Oscillatory Ventilation in ICU Patients
Atelectasis, hypoxemia, and ineffective sputum clearance are common problems in ICU patients. Continuous High-Frequency Oscillation (CHFO) is often considered to have a protective effect on the lungs.
- Conditions
- Atelectasis, Postoperative, Hypoxia, Critical Illness
- Trial name
- NCT06702813
- Testing
- High-Frequency Oscillatory Ventilation
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Shanghai Zhongshan Hospital
Sleep Initiation and Maintenance Disorders, Anxiety
HIRREM Developmental Study
The purpose of this study is to explore the functional and physiological effects associated with the use of High-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM), as supplemental care, for symptoms of…
- Conditions
- Sleep Initiation and Maintenance Disorders, Anxiety, Post-Traumatic Stress Disorder, Hot Flashes
- Trial name
- NCT02709369
- Testing
- HIRREM
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Wake Forest University Health Sciences
Chronic Prostatitis (CP), Chronic Pelvic Pain Syndrome (CPPS)
Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a condition with several causes of which some remain unknown. It is believed that some types of CP may be genetic or passed down (inherited) from one generation to the…
- Conditions
- Chronic Prostatitis (CP), Chronic Pelvic Pain Syndrome (CPPS), Painful Bladder Syndrome (PBS), Benign Frequency Syndrome (BFS)
- Trial name
- CP/CPPS (NCT00499317)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Boston Children's Hospital
Neurodegenerative Diseases, Osteoarthritis
Safety and Clinical Outcomes Study: SVF Deployment for Orthopedic, Neurologic, Urologic, and Cardio-pulmonary Conditions
To evaluate for any adverse effects that may be related to the administration and reception of autologous adipose derived stromal vascular fraction (SVF).
- Conditions
- Neurodegenerative Diseases, Osteoarthritis, Erectile Dysfunction, Autoimmune Diseases
- Trial name
- NCT01953523
- Testing
- Administration of autologous adipose derived SVF
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Elliot Lander