Clinical trials: Plaque Reduction
Gingival Hyperplasia, Dental Plaque
Clinical Efficacy of Chlorhexidine Varnish in Reducing Gingival Hyperplasia, Plaque Accumulation, and White Spot Lesions in Orthodontic Patients
This study investigates whether applying a chlorohexidine varnish (a dental coating) reduces gum overgrowth, plaque buildup, and early tooth decay (white spots) in patients with braces.
- Conditions
- Gingival Hyperplasia, Dental Plaque, Tooth Demineralization
- Trial name
- NCT07115784
- Testing
- Chlorhexidine Varnish
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Allogeneic Stem Cell Transplantation
Xylitol BSI Multisite - Reduction of Bloodstream Infections From Oral Organisms in Pediatric Stem Cell Transplant
Bloodstream infections (BSI) caused by bacteria translocating across injured oral mucosa are a significant cause of morbidity and mortality in patients undergoing stem cell transplantation (SCT).
- Trial name
- NCT05579639
- Testing
- Xylitol
- Where
- 3 sites in United States
- Volunteers
- 256 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Dental Plaque
A Protocol for the Use of Chlorhexidine Gluconate Saturation for the Reduction of Dental Biofilm Formation on Polymethylmethacrylate Restoration
Chlorhexidine gluconate (CHX), as an anti plaque agent, is commonly used with a variety of products. In this study we, the investigators at Hadassah Medical Organization, intend to examine the efficacy of a single dip in CHX of…
- Trial name
- NCT00259181
- Testing
- saturation of polymethylmethacrylate with chlorhexidine gluconate to reduce in vivo plaque formation
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Autism Disorder, Autism Spectrum Disorder (ASD
Effectiveness of Interactive Techniques on Oral Hygiene Skills in a Group of Autistic Egyptian Children
The present study will be performed to evaluate the effectiveness of peer modeling and audiovisual peer modeling video on toothbrushing skills in comparison to the visual pedagogical method at home.
- Conditions
- Autism Disorder, Autism Spectrum Disorder (ASD, Autism, Plaque Reduction
- Trial name
- Autism ASD (NCT07859696)
- Testing
- Peer model, Pre-recorded video of peer modeling, Pedagogical method
- Volunteers
- 90 people
- Sponsor
- Faculty of Dental Medicine for Girls
Cardiovascular Disease, Diabetes
The FLAVO Trial: Dietary Flavonoids and Cardiovascular Disease Risk Reduction in Postmenopausal Women With Type 2 Diabetes
The purpose of this placebo controlled trial is to determine whether a year long intervention with flavonoids (found in cocoa and soy) is more effective in reducing the risk of cardiovascular disease in postmenopausal women with…
- Trial name
- FLAVO (NCT00677599)
- Testing
- Flavonoid enrichment (cocoa / soy compounds)
- Where
- United Kingdom
- Volunteers
- 152 people
- Sponsor
- University of East Anglia
Dental Plaque, Gingivitis
Mechanical Plaque Control and Gingivitis Reduction in Fixed Appliance Patients
The purpose of this study is to determine whether the use of a sonic toothbrush alone is more effective than two other toothbrushing protocols on dental plaque elimination in patients with fixed orthodontic appliances.
- Trial name
- NCT00681135
- Testing
- sonic toothbrush (Philips Sonicare® FlexCare, Typ HX6942/04), manual toothbrush / interdental toothbrush (elmex® Inter X medium toothbrush / interdental brush Curaprox®), manual toothbrush (elmex® Inter X medium toothbrush)
- Where
- Germany
- Volunteers
- 118 people
- Sponsor
- Sebastian Zingler
Plaque, Dental, Caries, Dental
Livionex on Reducing Plaque Accumulation and Improving Oral Health in Children
This is an investigator initiated randomized double-blind pilot study at the UCSF Pediatric Dental Clinics to compare effectiveness of a new toothpaste Livionex Dental Gel with a standard children's toothpaste containing 1500 ppm…
- Conditions
- Plaque, Dental, Caries, Dental, Oral Hygiene
- Trial name
- NCT04368533
- Testing
- Livionex Dental Gel, A standard children's toothpaste containing 1500 ppm fluoride
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Atherosclerotic Plaque
Reduced Radiation Dose and IR-impact on Coronary Calcium Quantification
Evaluation of reduced radiation dose iterative reconstruction reconstructions for calcium scoring compared to full dose filtered back projection reconstructions
- Trial name
- NCT04267094
- Testing
- Iterative reconstruction at reduced radiation dose
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- University of Pennsylvania
Dental Caries
SDF vs Fluoride Varnish for Streptococcus Mutans Reduction in Children
This randomized split-mouth clinical trial will compare the effectiveness of 38% silver diamine fluoride (SDF) versus 5% sodium fluoride varnish (FV) in reducing salivary Streptococcus mutans levels in children with bilateral…
- Trial name
- Streptococcus (NCT07181967)
- Testing
- Sodium Fluoride Varnish (5%), Silver Diamine Fluoride (38%)
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Assiut University
Effectiveness of Charcoal-infused Versus Nylon Bristle Toothbrushes on Plaque Removal and Oral Bacterial Reduction in Children
Plaque Removal in Children Using Charcoal and Nylon Toothbrushes
This study will compare two types of toothbrushes in children: a charcoal-infused bristle toothbrush and a regular nylon bristle toothbrush.
- Trial name
- NCT07563400
- Testing
- soft charcoal infused bristle toothbrush (iLive) with bamboo handle, soft nylon bristle toothbrush (Oral B JUNIOR 6-12)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Reduction in DMFT Index and Plaque Index in Patients at the Treatment Completion, an Average of 4 Years, DMFT Index, ICDAS Score, Dental Plaque Index, Communication, Prevention, Dentist, Orthodontist
A New Digital Communication Tool Between Dentist and Orthodontist to Improve Dental Prevention
Dentists and orthodontists of the oral medicine department of Reims University Hospital noted that many children presented white spots around orthodontic brackets, or decays at the end of their multi-brackets orthodontic…
- Trial name
- ComDentODFPrev (NCT06517238)
- Testing
- There is no intervention
- Where
- France
- Volunteers
- 30 people
- Sponsor
- CHU de Reims
Dentinal Hypersensitivity, Plaque, Dental
Evaluation of Dental and Periodontal Health After IPR in Patients in Orthodontic Treatment With Clear Aligners
This study aimed to evaluate dental and periodontal health after interproximal enamel reduction and to compare Laser diode (a device used in the Orthodontic Program) and sodium fluoride (often used in the Orthodontic Program and…
- Conditions
- Dentinal Hypersensitivity, Plaque, Dental, Bleeding Gum
- Trial name
- NCT06685016
- Testing
- Evaluation of Dentin hypersensitivity with VAS scale
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Plaque Reduction
Digital vs. Parent Modeled Toothbrushing
This prospective randomized controlled trial will aim to evaluate the effectiveness of two methods of delivering oral hygiene instruction to children aged 3 - 6 years: parent-modeled toothbrushing (control) and the MoodBrush…
- Trial name
- NCT07441148
- Testing
- MoodBrush Digital Application
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Plaque Control
Triphala Tooth Wipes in Reduction of Streptococcus Mutans Colonies
This double-blind randomized clinical trial will be conducted among differently abled institutionalized children. Sixty participants aged 6-12 years with mild intellectual disability (ID) will be enrolled in the study and divided…
- Trial name
- NCT06575335
- Testing
- Triphala Tooth Wipe, Chlorhexidine Tooth Wipe
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences