Clinical trials: Plethysmography
Asthma
Validation of Structured Light Plethysmography: Asthma
Validation of Structured Light Plethysmography (SLP) in patients with asthma, in patients with acute asthma; an observational study in healthy participants and during patients' clinical investigation of broncho-reversibility in…
- Trial name
- SLPBD (NCT02543333)
- Where
- 2 sites in United Kingdom
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Pneumacare Ltd
Surgeries Undergoing General Anesthesia
PPV vs PVI in the Supine and Prone Position
This is a prospective study that will record the Pulse Pressure Variability (PPV) from the arterial line and Plethysmography Variability Index (PVI) from the pulse oximeter while the patient is in the supine position and then…
- Trial name
- NCT07415603
- Testing
- Observation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Joseph D. Tobias
Healthy
Effects of Miconazole on Blood Flow
This study will investigate the effect of the drug miconazole on blood vessel dilation. Miconazole stops production of EDHF, a substance that causes arteries to dilate. EDHF is produced by the cells that line blood vessels.
- Trial name
- NCT00004575
- Testing
- Miconazole, L-NMMA, Bradykinin
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Hypertension
Role of Endothelin in the Regulation of Vascular Tone in Patients With Essential Hypertension
Endothelin-1 (ET-1) is a powerful vasoconstricting peptide produced predominantly by vascular endothelial cells, that exerts its effect through the interaction with specific receptors, ETA and ETB, on the underlying smooth muscle…
- Trial name
- NCT00001527
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Hyperinsulinemia
Effect of Insulin on Endothelin-Dependent Vascular Tone in the Forearm Circulation
Previous studies have shown that insulin may stimulate the release of endothelin (ET) from endothelial cells. This mechanism may contribute to the adverse vascular effects determined by chronic hyperinsulinemia.
- Trial name
- NCT00001624
- Testing
- Insulin
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Lung Disease
A Clinical Study Aiming to Validate the Equipment: VoluSense Pediatrics (VSP)
This is a cross-sectional observational study, aiming to validate the accuracy of tidal breathing measurements in infants made by VoluSense Pediatrics, a lung function method based on electromagnetic inductance plethysmography…
- Trial name
- NCT02699268
- Testing
- Lung function measurement
- Where
- Norway
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Bronchiolitis
Pneumacare SLP Validation in Infants and in Clinical Bronchiolitis
A cohort observational study to characterise baseline Structured Light Plethysmography (SLP) outputs in infants with bronchiolitis and examine response to treatment using the Thora3DiTM
- Trial name
- NCT02881632
- Testing
- Structured Light Plethysmography (SLP) - Pneumscan
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospitals of North Midlands NHS Trust
Pulmonary Ventilation
Evaluation of Chest Wall Motion Symmetry During Ventilation in Healthy Subjects by Optoelectronic Plethysmography
Pulmonary ventilation is the only macroscopically observable breathing step. The ventilatory mechanism has been extensively studied and knowledge of its operation is now well established.
- Trial name
- EVAST (NCT06774118)
- Testing
- Data collection
- Volunteers
- 100 people
- Sponsor
- Université de Reims Champagne-Ardenne
Anorexia Nervosa
Validation of BodPod in Pediatric Anorexia Nervosa
Anorexia nervosa is a severe cause of undernutrition. It leads to a dramatic decrease of weight with an important modification of the body composition.
- Trial name
- PADAAM (NCT04321317)
- Testing
- Measure of body composition by Air Displacement Plethysmography (ADP)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Hospices Civils de Lyon
Perfusion Index, Plethysmography
Evaluation of Caudal Block and Ilioinguinal-ilioohypogastric Nerve Block Efficacy with Perfusion Index (PI)
The study is a prospective, randomised, controlled double-blind clinical trial. The primary aim was to evaluate the efficacy of caudal block and ilioinguinal-iliohypogastric nerve block with PI and PVI in pediatric inguinal…
- Conditions
- Perfusion Index, Plethysmography, Anesthesia, Caudal, Nerve Block
- Trial name
- NCT06203743
- Testing
- caudal block group, ilioinguinal-iliohypogastric nerve block group
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Premature Birth
Preterm Lung Function and Exercise Response Measured by OEP
This study will explore lung function and respiratory health in school-aged children who were born prematurely at <32 weeks gestation.
- Trial name
- NCT04239287
- Testing
- Lung function + exercise tests
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Asthma
Bronchial Dilation Test in Wheezy Infants
The purpose of the study is to establish the methodology of bronchial dilation test by salbutamol MDI with Spacer in wheezy infants with asthma and to evaluate the effects of atopy on the exacerbation of wheeze in wheezy infants.
- Trial name
- NCT03467776
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Guangzhou Institute of Respiratory Disease
Airway Obstruction
Airway Resistance Measurement in Children 3 to 6 Years of Age
In preschool aged children, the most suitable techniques to assess airway obstruction is debit interruption technic (Rint) and plethysmographic measure of specific airway resistance (sRaw).
- Trial name
- ARC36 (NCT02563210)
- Testing
- airway resistance measurement
- Where
- France
- Volunteers
- 130 people
- Sponsor
- University Hospital, Brest
Short Bowel Syndrome
Measurement of Body Composition by Air Displacement Plethysmography in Pediatric Intestinal Failure Patients
This study will determine if air-displacement plethysmography (ADP) provides accurate measurement of body composition (percent body fat and fat-free mass) in pediatric patients with intestinal failure, as compared to body…
- Trial name
- NCT02561819
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Christopher Duggan
Varicose Veins, Venous Insufficiency
Lower Limb Venous Insufficiency and the Effect of Radiofrequency Treatment Versus Open Surgery
200 patients with insufficient great saphenous veins will be randomized to either radiofrequency ablation or high ligation/stripping (open surgery).
- Trial name
- NCT02397226
- Testing
- Radiofrequency ablation, High ligation/stripping, Radiofrequency ablation catheter
- Where
- 2 sites in Sweden
- Volunteers
- 198 people
- Sponsor
- University Hospital, Linkoeping
Dysfunctional Breathing
Structured Light Plethysmography Against Standard of Care in the Diagnosis and Monitoring of Dysfunctional Breathing
This is an observational, controlled, single-centre study to validate the Thora3Di™ against standard practice in patients who are undergoing investigation for disproportionate breathlessness.
- Trial name
- SLPDB (NCT04255446)
- Testing
- Thora3DiTM
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pneumacare Ltd
In-patients Assessment of Vital Signs
Data Collection Study for RFP (Respiration From Plethysmogram)
The study will be conducted in hospitalised patients who undergo spot-check monitoring of vital signs as part of their routine care.
- Trial name
- SAT+ (NCT06633861)
- Testing
- spot-check measurement
- Where
- United Kingdom
- Volunteers
- 86 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Univentricular Heart, Lymphatic Abnormalities
Lymphatic Function in Patients With a Fontan Circulation From Brazil
It is suggested that the elevated central venous pressure in patients with a Fontan circulation can provoke manifestation of lymphatic dysfunction, met as plastic bronchitis, peripheral oedema and most feared protein-losing…
- Conditions
- Univentricular Heart, Lymphatic Abnormalities, Lymphatic Edema
- Trial name
- NCT04394507
- Testing
- Near-Infrared Fluorescence imaging, Strain Gauge Plethysmography
- Where
- 2 sites in Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Mesothelioma, Lung Neoplasms
Chest Wall Motion Analysis in Disease
Breathing movements, called chest wall motion, are very complex. The investigators are studying how movement of the abdomen, ribs and diaphragm contribute to breathing and how this differs with different diseases in the chest.
- Conditions
- Mesothelioma, Lung Neoplasms, Surgery, Cystic Fibrosis
- Trial name
- CWM (NCT02958683)
- Testing
- Chest wall motion analysis
- Where
- United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Heart of England NHS Trust
Pediatric Respiratory Diseases
Structured Light Plethysmography in Obstructive Airways Disease
Obstructive airways disease is the most common group of acute illnesses leading to hospital treatment in children. This group consists of different age-related diagnoses, such as bronchiolitis in infants or wheezing and asthma in…
- Trial name
- NCT03499938
- Testing
- Structured Light Plethysmography
- Where
- United Kingdom
- Volunteers
- 57 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust