Clinical trials: Pleural Effusion
Pleural Effusion
Normal Saline Flushing With And Without Heparin Lock In Maintaining Small Bore Intercostal Chest Catheter (ICC) Patency
Pleural diseases are among the most common clinical problems encountered in healthcare settings in Malaysia and even worldwide. Most patients presented in a hospital setting with pleural diseases will need pleural aspirations or…
- Trial name
- SENSHIP (NCT06314620)
- Testing
- Heparin saline lock, Without heparin saline lock
- Where
- Malaysia
- Volunteers
- 40 people
- Sponsor
- National University of Malaysia
Pleural Effusion
Use of the Triggering Receptor Expressed on Myeloid Cells-1 (TREM-1) in the Diagnosis of Pleural Effusion
The aim of this trial is to evaluate the level of TREM-1 in different kinds of pleural effusion.
- Trial name
- NCT00166894
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Pleural Effusion, Malignant
The Added Value of CT Scanning in Patients With an Unilateral Pleural Effusion
To investigate the diagnostic power of computed tomography for discriminating malignant from nonmalignant causes to pleural effusions in consecutive patients with no malignant cells found at a cytological examination and a chest…
- Trial name
- NCT03270215
- Testing
- Computed tomography
- Where
- Denmark
- Volunteers
- 232 people
- Sponsor
- Naestved Hospital
Pleural Effusion
Evaluation and Outcome of Para-pneumonic Effusion
Pleural effusion is the accumulation of excess fluid in the pleural cavity, which results in disturbance of the equilibrium between vascular hydrostatic and oncotic pressures.
- Trial name
- NCT03480490
- Testing
- Pleural fluid C-reactive protein
- Volunteers
- 25 people
- Sponsor
- Assiut University
Parapneumonic Pleural Effusion, Empyema
Clinical Trial Corticoids For Empyema And Pleural Effusion In Children
STUDY JUSTIFICATION 1. Scientific evidence of the usefulness of corticosteroid use for infectious diseases: Corticosteroids along with antibiotic use improve survival in some infectious processes provide long term benefits and…
- Trial name
- CORTEEC (NCT01261546)
- Testing
- Dexamethasone
- Where
- 8 sites in Spain
- Volunteers
- 60 people
- Sponsor
- Hospital Infanta Sofia
Bilateral Pleural Effusion
Impact of Large-Volume Pleural Effusions on Heart Function
The physiologic basis for relief from dyspnea after therapeutic thoracentesis remains poorly understood. Improvement of the heart and lung function may contribute to the dyspnea relief.
- Trial name
- TTE (NCT02548221)
- Testing
- transthoracic echocardiogram
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Beijing Chao Yang Hospital
Mycoplasma Pneumoniae Pneumonia
Effects of Oral Steroid in Mycoplasma Pneumoniae Pneumonia
Mycoplasma pneumoniae is one of the most common causes of community-acquired pneumonia in children. The clinical course is typically self-limited and benign; however, rare cases of severe pneumonia can develop despite appropriate…
- Trial name
- NCT02618057
- Testing
- Prednisolone, Levofloxacin
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Hospital
Pleural Effusion, Pleurisy
Yield of Cryoprobe vs Flexible Forceps Pleural Biopsy
This is a prospective study to assess the yield of pleural biopsy obtained with the routine flexible thoracoscopic biopsy forceps versus that obtained with a flexible cryoprobe during semirigid thoracoscopy
- Conditions
- Pleural Effusion, Pleurisy, Tuberculosis, Metastatic Malignancy
- Trial name
- COFFEE (NCT02500277)
- Testing
- Cryoprobe pleural biopsy first, Flexible forceps biopsy first
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Safety of Intervention, Efficacy of Intervention
Video-assisted Hyperthermic Pleural Chemoperfusion vs Talc Pleurodesis for Refractory Malignant Pleural Effusions.
Aim of this study is to compare two methods of pleurodesis for refractory malignant pleural effusions, in terms of safety and efficacy.
- Conditions
- Safety of Intervention, Efficacy of Intervention, Cost Effectiveness
- Trial name
- NCT01409551
- Testing
- VATS hyperthermic chemoperfusion, Bedside talc slurry pleurodesis
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Theagenio Cancer Hospital
Pleura; Effusion, Esophageal Adenocarcinoma
Outcomes of a Single Chest Drain vs Two Drains
Esophagectomy is a major surgical procedure done for carcinoma of esophagus. Usually bilateral chest tubes are placed in surgery for prevention of fluid accumulation in chest.
- Conditions
- Pleura; Effusion, Esophageal Adenocarcinoma, Esophageal Anastomotic Leak
- Trial name
- NCT07125248
- Testing
- Bilateral chest tube placement, Single drain placement
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Khyber Teaching Hospital
Peritoneum Cancer, Peritoneum Neoplasm
International Registry of Patients Treated With Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC)
Multicentric, international, web-based prospective documentation of the indications and results of Pressurized Aerosol Chemotherapy (so-called PIPAC or PITAC) for treating malignant pleural and peritoneal diseases.
- Conditions
- Peritoneum Cancer, Peritoneum Neoplasm, Pleural Cancer, Pleural Effusion
- Trial name
- PIPACRegis (NCT03210298)
- Testing
- PIPAC
- Where
- 16 sites in Argentina, Australia and 11 more
- Volunteers
- 1,000 people
- Sponsor
- Sabine Rhode
Pleural Tissue Culture
Pleural Tissue Culture Versus Pleural Fluid Culture in Infected Effusion
comparison between the result of fluid culture and that of pleural tissue culture
- Trial name
- NCT07140003
- Testing
- pleural biopsy
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Malignant Pleural Effusions, Recurrent Pleural Effusions
A Comparative Study of the Safety and Efficacy of Face Talc Slurry and Iodopovidone for Pleurodesis
Pleurodesis is a technique used to fuse the two layers of the lining over the lung. This is done to get rid of collections of fluid or air in this space.
- Conditions
- Malignant Pleural Effusions, Recurrent Pleural Effusions, Primary Spontaneous Pneumothorax, Secondary Spontaneous Pneumothorax
- Trial name
- NCT00430664
- Testing
- Pleurodesis with either talc or iodopovidone
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Pneumonia, Pleural Effusion
Pneumonia and Pleuropneumonia in Hospitalized Children
Describe the epidemiology of hospitalized pediatric pneumonia and pleuropneumonia with pleural effusion: frequency, clinical and biological characteristics, responsible bacteria and pneumococcus place, antibiotic resistance…
- Trial name
- NCT05274607
- Where
- France
- Volunteers
- 20,000 people
- Sponsor
- Association Clinique Thérapeutique Infantile du val de Marne
Pneumonia, Pleural Effusion
Physiotherapy Technique Decreases Respiratory Complications After Cardiac Operation
The objective of this study is to assess whether there is a difference between a care protocol with the use of incentive spirometry (Voldyne ®) and another with the application of NIV (non invasive ventilation with single-level…
- Conditions
- Pneumonia, Pleural Effusion, Atelectasis
- Trial name
- NCT01416519
- Testing
- Continuous Positive Airway Pressure (CPAP) facial mask, Assisted deep inspiration technique
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Santa Casa de Votuporanga
Pleural Effusion
Persistent Pleural Effusion Treatment Following Cardiothoracic Surgery by Platelet-Fibrin Glue
Persistent pleural effusion is a life-threatening complication after cardiac surgery. The traditional treatment is chest tube drainage, which may not respond to treatment.
- Trial name
- NCT06449131
- Testing
- Platelet-Rich Plasma and Fibrin Glue
- Where
- Iran
- Volunteers
- 19 people
- Sponsor
- Daryoush Hamidi Alamdari, PhD
Malignant Pleural Effusion
A Multicenter Survey Study Into Patient Experience With Mobile Apps
This multicenter prospective survey study is designed to evaluate a newly developed mobile app that will support patients with malignant pleural effusion (MPE) treated with an indwelling pleural catheter (IPC).
- Trial name
- NCT05130697
- Testing
- eMPowEr App
- Where
- Ireland
- Volunteers
- 20 people
- Sponsor
- National University of Ireland, Galway, Ireland
Malignant Pleural Effusion, Thoracic Cancer
Video Assisted Thoracoscopic Surgery (VATS) - Surgical Pleurodesis vs Tube Drainage in Management of Malignant Pleural Effusion (MPE)
Malignant Pleural Effusion (MPE) is considered to be a common presentation at malignant tumors representing 15% of all cancer cases. It carries a burden on our patients with dyspnea being the most common symptom in most of cases.
- Trial name
- NCT05872126
- Testing
- VATS-Surgical pleurodesis, Tube Drainage
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University