Clinical trials: Polytrauma Patients
Hemorrhagic Shock, Trauma
A Comparison of Two Target Mean Arterial Pressures in the Resuscitation of Hypotensive Trauma Patients
The goal of this study will be to determine if a lower than normal blood pressure during surgery for bleeding in the abdomen or chest will result in decreased bleeding and decreased chance of death.
- Conditions
- Hemorrhagic Shock, Trauma, Wounds, Penetrating, Shock, Traumatic
- Trial name
- NCT00459160
- Testing
- Intraoperative Hypotensive Resuscitation
- Where
- United States
- Volunteers
- 271 people
- Sponsor
- Baylor College of Medicine
Injury, Trauma
Management of Major Trauma Patients at Aarau Trauma Center - Evaluation of Processes and Patient Outcome
Quality control and improvement project: Assessment and analysis of processes and outcome in trauma emergency room and major trauma patients at the Aarau trauma center (cantonal hospital) with regard to initial emergency…
- Conditions
- Injury, Trauma, Major Trauma, Multiple Trauma
- Trial name
- NCT02165137
- Where
- Switzerland
- Volunteers
- 3,800 people
- Sponsor
- Kantonsspital Aarau
Multiple Trauma, Massive Bleeding
Evaluation of the TICCS Capacity to Identify Trauma Patients With Acute Coagulopathy and Massive Bleeding
A prospective single-centre non-comparative non-interventional open study has been designed to validate, in a target number of 100 trauma patients, the correlation between TICCS evaluated on the site of injury and…
- Conditions
- Multiple Trauma, Massive Bleeding, Early Complication of Trauma
- Trial name
- NCT02132208
- Where
- Belgium
- Volunteers
- 82 people
- Sponsor
- Centre Hospitalier Régional de la Citadelle
Multiple Trauma/Injuries
Collecting the Results of Multiple Trauma Patients and Find the Correlation of Morality and Mobility
Collect data about physiological examination values, blood test values and radiological examination results of patients admitted to the hospital for major trauma.
- Trial name
- trauma (NCT06216873)
- Testing
- multiple trauma
- Where
- 2 sites in Taiwan
- Volunteers
- 400 people
- Sponsor
- St. Martin De Porress Hospital
Trauma Centers/Statistics & Numerical Data, Trauma Blunt
Results of Medical and Nursing Record,Physical Examination, Blood Test and Radiological Examination of Multiple Trauma to Find the Correlation With Patient's Morality and Mobility
This study aims to analyze statistical data on physiological examination values, blood test results, and radiological findings in patients admitted to the emergency department for severe trauma.
- Conditions
- Trauma Centers/Statistics & Numerical Data, Trauma Blunt, Trauma (Including Fractures), Trauma Abdomen
- Trial name
- trauma (NCT07903727)
- Testing
- Collect results of trauma patients
- Volunteers
- 700 people
- Sponsor
- St. Martin De Porress Hospital
Injuries, Multiple, Norway/Epidemiology
Trauma Registration at St. Olavs Hospital 2000-2003
St. Olavs Hospital is a trauma referral center in the region of Midtnorge. Admitting trauma patients locally and those referred from hospitals in Nord-Trøndelag, Sør-Trøndelag and Møre-Romsdal.An active trauma team was defined in…
- Conditions
- Injuries, Multiple, Norway/Epidemiology, Trauma Centers/Statistics & Numerical Data, Trauma, Multiple
- Trial name
- NCT00184470
- Volunteers
- 1,000 people
- Sponsor
- Norwegian University of Science and Technology
Traumatic Injuries, Prehospital Emergency Care
Study of Pre Hospital Management of Polytrauma Patients by Medical Teams From a Department in the Parisian Region
To study the impact of prehospital management duration by SMUR teams in the Essonne department (91) on early patient mortality (within 24 hours) and to analyze the procedures performed on scene.
- Conditions
- Traumatic Injuries, Prehospital Emergency Care, Early Mortality
- Trial name
- DELTA-91 (NCT07414186)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Sud Francilien
Tranexamic Acid Effect in Pediatric Polytraumatized Patients
Tranexamic Acid Effect in Pediatric
The study will compare mortality and blood transfusion amounts among severely polytraumatized pediatrics who did or did not receive tranexamic acid within 3 h of injury, based on Injury Severity Score (ISS) and indicators of…
- Trial name
- NCT06097611
- Testing
- Tranexamic Acid administration
- Volunteers
- 74 people
- Sponsor
- Assiut University
Trauma
Comparative Analysis of MGAP and GAP Trauma Scores in Predicting Outcomes for Multiple Trauma Patients
The goal of this prospective cohort study is to compare the predictive accuracy of the MGAP and GAP trauma scores in determining the prognosis of multiple trauma patients admitted to the emergency department at Al-Kadhimiya…
- Trial name
- MGAP-GAP (NCT06732791)
- Where
- Iraq
- Volunteers
- 522 people
- Sponsor
- Al-Nahrain University
Emergencies, Trauma Injury
Pre-Hospital Zone 1 Partial Resuscitative Endovascular Balloon Occlusion of the Aorta for Injured Patients With Exsanguinating Sub-diaphragmatic Haemorrhage
It is unknown whether this evolved strategy (Pre-Hospital Zone I P-REBOA) is feasible and with an acceptable safety profile. This study will address this question, therefore informing the design of a prospective multicentre…
- Conditions
- Emergencies, Trauma Injury, Trauma, Multiple
- Trial name
- P-PRO (NCT04145271)
- Testing
- Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA)
- Where
- 4 sites in United Kingdom
- Volunteers
- 10 people
- Sponsor
- Barts & The London NHS Trust
Limb Fracture
Impact of Continuous Regional Analgesia in Severe Trauma Patients
Regional analgesia, based on its physiological effects and efficacy, is used for optimal perioperative pain relief. However, for acute pain in multiple trauma patients in a critical condition, it has not been prospectively…
- Trial name
- ALRréa (NCT04546503)
- Testing
- Continuous Regional analgesia, Control Group
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Acute Kidney Injury
Acute Kidney Injury in Pediatric Polytrauma Patients at Assiut University Trauma Unit: A Cross-Sectional Study on Incidence and Predictive Risk Factors
This study aims to investigate the true incidence and clinical presentation of post-traumatic AKI in hospitalized pediatric patients and identify the risk, and severity of AKI.
- Trial name
- NCT06177886
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hemorrhage, Shock, Traumatic
The AT-REBOA Target Trial
Temporary aortic occlusion can limit haemorrhage, can help to maintain perfusion to the heart and brain, and may be associated with improved survival.
- Conditions
- Hemorrhage, Shock, Traumatic, Cardiac Arrest Due to Trauma, Polytrauma
- Trial name
- AT-REBOA (NCT06312436)
- Testing
- Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA)
- Where
- 2 sites in Austria
- Volunteers
- 44 people
- Sponsor
- Medical University of Graz
Polytraumatism
Treatment of Polytraumatisms With Corticoids
Interest of treatment of polytraumatisms with corticoids (hydrocortisone) for patient with relative adrenocortical insufficiency on frequency of nosocomial infection, and hemodynamic complications and organs injuries.
- Trial name
- Hypolyte (NCT00563303)
- Testing
- hydrocortisone, NaCl
- Where
- 7 sites in France
- Volunteers
- 150 people
- Sponsor
- Nantes University Hospital
Multiple Trauma
Thoracic Injuries in Pediatric Polytraumatized Patients: Epidemiology, Treatment and Outcome
The present study predicts that concomitant chest injuries in polytraumatized pediatric patients are a potential source of substantial morbidity and mortality.
- Trial name
- NCT02398175
- Testing
- reanimation/intubation
- Volunteers
- 71 people
- Sponsor
- Medical University of Vienna
Multiple Trauma, Traumatic Brain Injury
Spinal Clearance Study: Expediting the Spinal Clearance Process in the Major Trauma Patient
The Alfred Hospital receives approximately 40% of the major trauma patients in Victoria, all of whom are at risk for spinal injuries.
- Conditions
- Multiple Trauma, Traumatic Brain Injury, Spinal Injuries
- Trial name
- NCT00163826
- Where
- Australia
- Volunteers
- 299 people
- Sponsor
- Bayside Health
Polytrauma
Analysis of Urogenital Injuries in Polytraumatized Patients
Urogenital injuries occur in approximately 5-10 % of all severly injured patients. The literature lacks a thorough investigation into the mechanisms of trauma, the analysis of the whole urogenital tract and especially the…
- Trial name
- NCT05074095
- Testing
- retrospective analysis
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Kidney Injury
Acute Kidney Injury in Poly Trauma Patients
The aim of this study is to identify the incidence and the factors associated with acute kidney injury in adult poly trauma patients
- Trial name
- NCT06108765
- Volunteers
- 100 people
- Sponsor
- Assiut University
Multiple Trauma, Pain, Acute
Intranasal Ketamine Versus Intranasal Fentanyl
Abstract Background: Given the inadequate control of pain in patients with injury that refer to the emergency departments, the rapid onset of action of intranasal administration in pain management, and the avoidance of…
- Trial name
- NCT04414800
- Testing
- Ketamine, Fentanyl
- Where
- Iran
- Volunteers
- 125 people
- Sponsor
- Isfahan University of Medical Sciences
Critical Illness, Pediatrics
Effect of Giving Reduced Fluid in Children After Trauma
This study is designed to help decide how much intravenous (IV) fluid should be given to pediatric trauma patients. No standard currently exists for managing fluids in critically ill pediatric trauma patients, and many fluid…
- Conditions
- Critical Illness, Pediatrics, General Surgery, Fluid Therapy
- Trial name
- NCT04201704
- Testing
- Balanced crystalloid solution volume administration, Packed Erythrocytes Units, Blood Product Unit volume, Plasma volume
- Where
- 4 sites in United States
- Volunteers
- 250 people
- Sponsor
- Columbia University