Clinical trials: Post-Tonsillectomy
Cheilitis, Angular, Postoperative Complications
Using Dexpanthenol Cream to Prevent Lip Corner Cracks in Children After Tonsil/Adenoid Surgery
Soreness and cracking at the corners of the mouth, a condition called angular cheilitis, can be an uncomfortable problem for children after they have surgery to remove their tonsils and adenoids.
- Conditions
- Cheilitis, Angular, Postoperative Complications, Adenotonsillar Hypertrophy
- Trial name
- PrevAC-PedAT (NCT07002632)
- Testing
- Dexpanthenol 5 % Topical Ointment
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Tonsillectomy, Adenoidectomy
IV Acetaminophen and Post-Tonsillectomy Pain
This study is a randomized prospective study to compare the post-operative analgesic efficacy of intravenous acetaminophen 15 mg/kg to an equal volume of 0.9% normal saline when all other analgesic interventions have been…
- Trial name
- NCT03883893
- Testing
- Intravenous acetaminophen, Normal saline
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pain
iPad for Post Operative Pain After Tonsillectomy
The purpose of this study is to determine the clinical effectiveness of presenting iPads (Tablet Based Interactive Distraction) to pediatric patients following tonsillectomies/adenotonsillectomies.
- Trial name
- NCT07770529
- Testing
- iPad, Intervention Control
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Postoperative Pain, Postoperative Nausea and Vomiting
Effect of Steroids on Post-tonsillectomy Morbidities
This study aims to evaluate the effect of postoperative systemic rapid onset and short acting dexamethasone followed by a tapering dose of oral prednisolone on post-tonsillectomy morbidities.
- Trial name
- NCT02401529
- Testing
- IV dexamethasone, Oral prednisolone, Paracetamol
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Fahd General Hospital
Post Tonsillectomy Emergence Agitation
Melatonin for Post Tonsillectomy Emergence Agitation in Pediatric
The goal of this clinical trial is to learn if melatonin can decrease emergence agitation in pediatric post tonsillectomy. The main questions it aims to answer are: Does melatonin decrease emergence agitation in pediatric post…
- Trial name
- NCT07375342
- Testing
- Melatonin
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Benha University
Emergence Agitation, Emergence Delirium
Transcutaneous Auricular Vagus Nerve Stimulation for Prevention of Emergence Agitation and Delirium in Children Undergoing Tonsillectomy and Adenoidectomy
Brief Summary This study is designed to find out whether transcutaneous auricular vagus nerve stimulation (taVNS) can safely reduce restlessness and confusion when children wake up from anesthesia after tonsillectomy and…
- Trial name
- NCT07394647
- Testing
- Active taVNS Group
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
Post Operative Pain, Postoperative Hemorrhage
Efficacy of Local Infiltration of Tranexamic Acid and Lidocaine in Tonsillar Bed on Postoperative Bleeding and Pain During Tonsillectomy Surgery: Prospective, Randomized, Control Study
All anesthetic techniques aim to lessen intra-operative surgical site bleeding because it is a major problem and does not help with precision, surgery time, or postoperative wound healing.
- Trial name
- NCT05817474
- Testing
- lidocaine (2 %) 2 ml and tranexamic acid
- Where
- Egypt
- Volunteers
- 94 people
- Sponsor
- mohamed
Postoperative Pain, Acute Pain
Pharmacokinetic, Efficacy and Safety Study of Tapentadol Oral Solution in Children With Postoperative Pain
To find out if a drug called tapentadol administered by mouth safely relieves pain in children. Look at the amount of tapentadol in the blood after a single oral dose.
- Trial name
- NCT01729728
- Testing
- Tapentadol
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Grünenthal GmbH
Post Tonsillectomy Pain
A Comparative Study With Parenteral Oxycodone, Morphine and Dexamethasone in Postoperative Pain in Paediatric Patients
The aim of this randomized, double-blind study is to compare parenteral pre-emptive oxycodone, morphine and dexamethasone with placebo in the treatment of postoperative pain in paediatric patients 4 to 12 years of age.
- Trial name
- DOM (NCT00733083)
- Testing
- 0,1 mg/kg of oxycodone, Morphine 0,1 mg/kg, Dexamethasone 0,5 mg/kg
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- University of Turku
Emergence Agitation, Emergence Delirium
Effect of Nebulized Lignocaine on Emergence Agitation After Sevoflurane Anesthesia in Pediatric Patients Undergoing Tonsillectomy
Emergence agitation is a frequent recovery complication in young children following general anesthesia with sevoflurane. It is characterized by confusion, crying, disorientation, and non-purposeful thrashing during early…
- Conditions
- Emergence Agitation, Emergence Delirium, Postoperative Pain
- Trial name
- NCT07871266
- Testing
- Lidocaine, 0.9% Normal Saline
- Volunteers
- 60 people
- Sponsor
- Assiut University
Tonsillectomy
Celecoxib After Tonsillectomy
Tonsillectomy is one of the most common pediatric surgical procedures in the United States. Postoperative pain is substantial, with typical regimens employing narcotic derivatives and acetaminophen for 1-2 weeks after surgery.
- Trial name
- NCT02934191
- Testing
- Celecoxib, Acetaminophen, Oxycodone
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Children's Hospital of Philadelphia
Sleep-Disordered Breathing, Sleep Apnea Syndromes in Children
Lateral Pharyngoplasty Outcomes in Children Undergoing Tonsillectomy
The goal of this treatment study is to determine if doing lateral pharyngoplasty with tonsillectomy is better for children than doing tonsillectomy alone.
- Conditions
- Sleep-Disordered Breathing, Sleep Apnea Syndromes in Children, Sleep Apnea, Obstructive, Tonsillitis
- Trial name
- NCT05575401
- Testing
- Lateral pharyngoplasty, Tonsillectomy
- Where
- 4 sites in United States
- Volunteers
- 160 people
- Sponsor
- Loma Linda University
Post Tonsillectomy Pain, Post Operative Analgesia
Transnasal Sphenopalatine Ganglion Block for Postoperative Pain and Recovery in Tonsillectomy (TONwoPA)
The aim of this clinical trial is to evaluate the effectiveness of transnasal transmucosal sphenopalatine ganglion block in reducing post-tonsillectomy pain.
- Conditions
- Post Tonsillectomy Pain, Post Operative Analgesia, Opioid Consumption, Sphenopalatine Ganglion Block
- Trial name
- TONwoPA (NCT07370129)
- Testing
- Transnasal Transmucosal Sphenopalatine Ganglion Block, Lidocaine %5, Saline (0.9% NaCl)
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Ankara University
Post-tonsillectomy Pain, Post-tonsillectomy Activity
The Effects of Reducing Stomach Acid on Post-tonsillectomy Pain
This study was designed to determine whether post-operative pain following a tonsillectomy can be reduced by adding an antacid-like medication to the medications taken after surgery.
- Conditions
- Post-tonsillectomy Pain, Post-tonsillectomy Activity, Post-tonsillectomy Hydration
- Trial name
- NCT00472186
- Testing
- Lansoprazole
- Where
- 2 sites in United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Hemorrhage, Pain
Effect of Tonsillar Pillar Closure on Postoperative Pain and Bleeding Risk After Tonsillectomy
The purpose of this study is to determine if closing the tonsil fossa after tonsillectomy leads to less pain and bleeding risk than leaving it open to heal by secondary intention.
- Trial name
- NCT00394849
- Testing
- suture one tonsillar fossa
- Where
- United States
- Volunteers
- 763 people, healthy volunteers welcome
- Sponsor
- Indiana University
Post Tonsillectomy Pain
The Effect of Pre Surgery Dog Visits on Post Surgery Consumption of Pain Medication
The objective of this study is to examine the effects of pre surgery dog visits as compared to a costumed character or parents-only on the consumption of pain medication after surgery.
- Trial name
- Dog (NCT00452738)
- Testing
- Therapy dog, Costumed character, Parents-only
- Where
- United States
- Sponsor
- Oklahoma State University Center for Health Sciences
Pain Management
Pain Management in Pediatric Adenotonsillectomy
Tonsillectomy is considered one of the most frequent minor surgeries conducted on a day-case basis on children, and usually associated with pain and sore throat.
- Trial name
- AZU (NCT05928520)
- Testing
- Tramadol 5%, Lidocaine 2%
- Volunteers
- 80 people
- Sponsor
- Al-Azhar University
Tonsillectomy, Adenoidectomy
Postoperative Ibuprofen and the Risk of Bleeding After Tonsillectomy With or Without Adenoidectomy
Tonsillectomy (the surgical removal of the tonsils) is a commonly performed surgery in children. One risk of tonsillectomy is postoperative bleeding, and this can be more dangerous in children because their blood volume is lower…
- Trial name
- NCT01605903
- Testing
- Ibuprofen, Acetaminophen
- Where
- 5 sites in United States
- Volunteers
- 741 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Tonsillectomy
Postoperative Oral Corticosteroids Following Tonsillectomy
Tonsillectomy is one of the most common surgical procedures in the United States, and post-operative pain management is a challenge for otolaryngologists.
- Trial name
- NCT03352115
- Testing
- Prednisolone
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Tonsillitis, Obstructive Sleep Apnea of Child
Steroids and Pain Control After Tonsillectomy
This research study aims to find out if a single oral dose of steroid after tonsillectomy will reduce pain and decrease the need for narcotic medications.
- Trial name
- NCT03995628
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- Medical University of South Carolina