Clinical trials: Post-Traumatic
Primary Arthrosis, Post Traumatic Arthritis
2-Year Post-Approval Study to Investigate the Scandinavian Total Ankle Replacement System (STAR) Ankle Under Actual Conditions of Use
This post-approval study is being conducted to examine the performance of the STAR Ankle under actual conditions of use.
- Conditions
- Primary Arthrosis, Post Traumatic Arthritis, Rheumatoid Arthritis, Osteoarthritis
- Trial name
- STAR 2 PAS (NCT01284283)
- Testing
- Scandinavian Total Ankle Replacement System (STAR Ankle)
- Where
- 9 sites in United States
- Volunteers
- 102 people
- Sponsor
- Encore Medical, L.P.
Vicarious Trauma, Psychological Distress
Efficacy of Vicarious Post-Traumatic Growth Intervention for Nurses in Emergency Units
This randomized controlled trial aims to evaluate the efficacy of a Vicarious Post-Traumatic Growth (VPTG) Intervention among nurses working in emergency units.
- Conditions
- Vicarious Trauma, Psychological Distress, Post-Traumatic Growth, Psychological, Psychological Well-being
- Trial name
- VPTG-RCT (NCT07677527)
- Testing
- Psychoeducational Vicarious Post-Traumatic Growth Intervention
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fatima Jinnah Women University
Nightmares Associated With Trauma and Stress
Exposure, Relaxation, & Rescripting Therapy-Child
Untreated trauma-related nightmares and sleep-related disorders are associated with chronic health problems, burdening both the suffering individual and the health-care system.
- Trial name
- ERRT-C (NCT01776229)
- Testing
- Exposure, Relaxation, & Rescripting Therapy-Child
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Tulsa
Posttraumatic Stress Disorders
Ifenprodil Tartrate Treatment of Adolescents With Post-traumatic Stress Disorder: a Double-blind, Placebo-controlled Trial
Accumulating evidence suggests a key role of the N-methyl-D-aspartate (NMDA) receptor in the pathophysiology of post-traumatic stress disorder (PTSD).
- Trial name
- NCT01896388
- Testing
- Ifenprodil Tartrate
- Where
- Japan
- Volunteers
- 10 people
- Sponsor
- Chiba University
Suicide and Depression
Characterizing Inflammatory Profiles and Suicidal Behavior in Adolescents
Despite increasing suicide rates in adolescents, there remains a paucity of approaches to use to prevent re-attempts. Any hope for breaking the code to prevent youth suicide lies in understanding biological factors that play a…
- Trial name
- NCT04783506
- Testing
- Observational Study
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Posttraumatic Stress Disorders, PTSD
Effect of D-cycloserine on Treatment of Posttraumatic Stress Disorder (PTSD) in Youth
The purpose of this study is to show whether D-cycloserine in combination with cognitive behavioral therapy (CBT) is more effective than CBT plus placebo to reduce symptoms of posttraumatic stress disorder (PTSD) in 7-12 year old…
- Trial name
- NCT01157416
- Testing
- D-cycloserine, CBT
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Tulane University School of Medicine
Traumatic Brain Injury (TBI)
Prognostic Model for Predicting Outcome After Moderate to Severe Paediatric Traumatic Brain Injury
Due to ethical and logistical challenges related to paediatric research, there is limited age-appropriate evidence for managing paediatric traumatic brain injury (pTBI).
- Trial name
- PROMPT (NCT07538440)
- Where
- United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Posttraumatic Stress Disorder
PROlonGed ExpoSure Sertraline
The current research study aims to compare the effectiveness of two proven treatments for posttraumatic stress disorder (PTSD): Prolonged Exposure (PE), sertraline, and their combination.
- Trial name
- PROGrESS (NCT01524133)
- Testing
- Sertraline, Prolonged Exposure Therapy
- Where
- 4 sites in United States
- Volunteers
- 223 people
- Sponsor
- VA Ann Arbor Healthcare System
Post Traumatic Stress Disorder, Depression
Randomized Control Trial on Trauma Focused CBT in Zambia
The purpose of this study is to study the effectiveness of Trauma Focused Cognitive Behavioral Therapy in subset of children who are affected by trauma with significant mental health symptomatology in order to 1) examine the…
- Conditions
- Post Traumatic Stress Disorder, Depression, Risk Behaviors
- Trial name
- NCT01624298
- Testing
- Trauma Focused Cognitive Behavioral Therapy
- Where
- Zambia
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Post-Traumatic Stress Disorder, Depression
Efficacy of EMDR Versus CBT for Post-Traumatic Stress Disorder in Pakistan
This randomized controlled trial compares Eye Movement Desensitization and Reprocessing (EMDR) therapy with Cognitive Behavioral Therapy (CBT) for the treatment of post-traumatic stress disorder (PTSD) in Pakistan.
- Conditions
- Post-Traumatic Stress Disorder, Depression, Anxiety
- Trial name
- NCT06435052
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR) Therapy, Cognitive Behavioral Therapy (CBT)
- Where
- 3 sites in Pakistan
- Volunteers
- 80 people
- Sponsor
- Khushal Khan Khattak Univeristy, Karak, Pakistan
Acute Traumatic Stress Disorders, Post-Traumatic Stress Disorders
Evaluation of Stress Disorders
The purpose of this study is to examine the short-term consequences of trauma and to determine the effectiveness of the drug sertraline in preventing and treating post-traumatic stress disorder (PTSD) and acute stress disorder…
- Trial name
- NCT00050804
- Testing
- sertraline
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Agoraphobia, Social Phobia
Can Thought Field Therapy (TFT) be Helpful for Patients With an Anxiety Disorder?
The purpose of this study is to find out if Thought Field Therapy has effect on certain anxiety disorders; agoraphobia, social phobia, and post traumatic stress disorder (PTSD).
- Conditions
- Agoraphobia, Social Phobia, PTSD
- Trial name
- NCT00202709
- Testing
- Thought Field Therapy (TFT)
- Where
- Norway
- Volunteers
- 52 people
- Sponsor
- Sorlandet Hospital HF
Tibial Fractures
Results of Cross-leg Free Vascularized Fibular Graft
This study aims to evaluate the new technique of cross-leg vascularized fibular graft for reconstruction of post-traumatic long tibial bone defects in terms of restoring normal anatomy and function of the traumatized limb in a…
- Trial name
- NCT06491316
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Assiut University
Post Trauma Nightmares, Traumatic Stress
Exposure, Relaxation, & Rescripting Therapy-Child
The study implements a trauma-related nightmare treatment for children aged 8 to 13 years. Relevant outcome progress and outcome measures on symptoms, nightmare distress and duration, academic indicators, and sleep quality will…
- Trial name
- ERRT-C (NCT02184026)
- Testing
- Exposure, Relaxation, & Rescripting Therapy-Child
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Montana
Osteoarthritis, Post-traumatic; Arthrosis
Long Term Sidus PMCF
The objectives of this study are to assess the safety and performance of the Sidus Stem-Free Shoulder Arthroplasty System in unilateral primary total shoulder arthroplasty.
- Trial name
- NCT04063943
- Testing
- Sidus Stem-Free Shoulder
- Where
- 7 sites in United States, Canada
- Sponsor
- Zimmer Biomet
Post Traumatic Stress Disorder
Building Resilience Against ViolencE (BRAVE)
The study has both quantitative and qualitative components. The objective of the quantitative study is: To evaluate the effectiveness of Learning Through Play (LTP) Plus culturally adapted Trauma Focused Cognitive Behavior…
- Trial name
- BRAVE (NCT03488290)
- Testing
- LTP Plus TF-CBT, Treatment as Usual
- Where
- 2 sites in Pakistan
- Volunteers
- 300 people
- Sponsor
- Pakistan Institute of Living and Learning
Concussion, Brain
Post-acute Structured Exercise Following Sport Concussion
This study will investigate the effect of structured, standardized aerobic exercise (AE) compared to usual care on clinical recovery from sport-related concussion (SRC) within the post-acute phase of injury.
- Trial name
- NCT02969824
- Testing
- Supervised Aerobic Exercise
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- University of Toronto
Post Traumatic Stress Disorder
Technology-Based Tools to Enhance Quality of Care in Mental Health Treatment
Nearly 9 million U.S. children (1 in 8) meet criteria for at least one mental health disorder at any point in time. Effective treatments exist for these disorders, but children and families who seek services rarely receive them…
- Trial name
- NCT01915160
- Testing
- eTF-CBT, TF-CBT
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
PTSD - Post Traumatic Stress Disorder
Intensive Trauma-Focused Treatment for Adolescents With PTSD: Feasibility and Preliminary Effects
Post-Traumatic Stress Disorder (PTSD) in adolescents is a debilitating condition that, without timely intervention, risks becoming chronic and severely impairing development.
- Trial name
- NCT07052474
- Testing
- Intensive trauma-focused treatment
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Karolinska Institutet
Injury Traumatic, Injuries
Trauma Follow-Up Prediction (Project 2: Aim 2)
Approximately 9% of the world's deaths, more than 5 million deaths annually, are due to injury. In high-income countries, where the epidemiology and outcomes of traumatic injury are well characterized, trauma primarily affects…
- Trial name
- NCT05464017
- Testing
- Optimized version of the mHealth screening tool (intervention) using the machine learning approach
- Volunteers
- 852 people, healthy volunteers welcome
- Sponsor
- University of Buea