Clinical trials: Post-operative Pain Control
Failed Moderate Sedation During Procedure
The Effects of Single-dose Rectal Midazolam Application on Post-operative Recovery
This study aimed to compare the efficiency of rectal midazolam addition after applying bupivacaine and caudal anesthesia on postoperative analgesia time, the need for additional analgesics, postoperative recovery, sedation, and…
- Trial name
- NCT02127489
- Testing
- 1 mL/kg bupivacaine 0.25%.
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Karadeniz Technical University
Postoperative Pain
Infra-orbital Nerve Block for Post Operative Analgesia in Children Undergoing Cleft Lip Surgery.
this study will be undertaken to evaluate the safety and analgesic efficacy of adding ketamine to bupivacaine in bilateral infra-orbital nerve block for relief of pain postoperatively following repair of cleft lip in children…
- Trial name
- IFONB (NCT02514980)
- Testing
- Bupivacaine, Ketamine
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Impacted Mandibular Third Molar Extraction, Post Operative Complications
A Comparison of Recovery After Impacted Wisdom Tooth Removal
Justification of the Study There is a high prevalence of impacted third molars, often accompanied by a range of postoperative complications.
- Trial name
- CESE-3M (NCT07304882)
- Testing
- serratiopeptidase, Escin, Conventional drugs
- Where
- Yemen
- Volunteers
- 24 people
- Sponsor
- University of Science and Technology, Yemen
ACL Injury, Post Operative Pain
iPACK for Post-op Pain Following ACL Reconstruction
This study will consist of patients 12 years and older undergoing ACL reconstruction using a quadriceps or bone-patella tendon bone (BTB) graft.
- Trial name
- NCT05498870
- Testing
- Adductor Canal Block (ACB) Only, Adductor Canal Block (ACB) + iPACK Block
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Medical University of South Carolina
Post Operative Pain, Inguinal Hernia
Comparison of Two Different Analgesic Regional Block Techniques in Pediatric Patients Undergoing a Hernia Repair
Lower abdominal operations; especially inguinal hernia repairs are one of the most frequently performed operations in the daily practice of pediatric surgeries.Regional anesthesia techniques are frequently and effectively used…
- Trial name
- NCT05896072
- Testing
- Erector Spinae Plane Block, Caudal Block
- Where
- 7 sites in Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Abant Izzet Baysal University
Pain
Betamethasone to Control Postoperative Pain in Emergency Endodontic Care
The objective of this randomized double-blind study was to evaluate the effect of betamethasone in the control of postoperative pain in patients undergoing endodontic treatment.
- Trial name
- NCT02865746
- Testing
- Bethametasone
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Tonsillectomy, Post-Operative Pain
Acupuncture for Post-tonsillectomy Pain Control in Children
A randomized, controlled, single-blinded study comparing conventional postoperative analgesia with paracetamol-on-demand with the same regime plus acupuncture.
- Conditions
- Tonsillectomy, Post-Operative Pain, Acupuncture
- Trial name
- NCT01285687
- Testing
- acupuncture
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Ziv Hospital
Postoperative Analgesia
Analgesic Techniques for Robotic Prostatectomy Procedures
Robot-assisted radical prostatectomy and robot-assisted simple prostatectomy are minimally invasive procedures associated with reduced postoperative pain compared to open surgery.
- Trial name
- PROPAIN (NCT07483840)
- Testing
- Thoracic Erector Spinae Plane Block (ESPB-T), Rectus Sheath Block (RSB), Low-dose Spinal Analgesia (SA)
- Where
- Italy
- Volunteers
- 147 people
- Sponsor
- Ente Ospedaliero Ospedali Galliera
Post Operative Pain, Appendicitis
Evaluation of Local Anesthetic at Incision Site
Patient will have usual appendectomy surgery with an injection of local or saline at incision site either before or after the incision at random.
- Trial name
- NCT02483689
- Testing
- Pre Incisional Local Anesthetic, Pre-Incisional Saline, Post-Closure Local Anesthetic
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Valley Anesthesiology Consultants
Abdominal Cancer
Comparsion Between Intravenous Infusion of Ketofol and Inhalational Anasthetics in Abdominal Cancer Surgeries for Post Operative Analgesia
( post operative pain between intravenous infusion ketofol and standard inhalational general anesthesia in abdominal cancer surgeries )
- Trial name
- NCT06265948
- Volunteers
- 80 people
- Sponsor
- Assiut University
Hip Fractures
Comparison of PENG Block and Fascia Iliaca Compartment Block in the Postoperative Pain Control of Hip Capsular Fracture
A prospective cohort study comparing PENG block versus iliac fascia block with the aim of evaluating its effectiveness in the peri-surgical analgesia of intracapsular femoral fracture.
- Trial name
- NCT05377541
- Testing
- Surgical treatment of femur fracture
- Where
- Spain
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Consorci Sanitari de Terrassa
Hip Surgery, Post Operative Pain Control
Post Operative Pain Control After Pediatric Hip Surgery
Hip surgery in children is painful and the optimal modality for managing post-operative pain has not been established. This prospective randomized controlled trail compares lumbar plexus catheter (LPC), lumbar epidural catheter…
- Trial name
- NCT03435692
- Testing
- Lumbar Plexus Catheter, Lumbar Epidural Catheter, Patient Controlled Analgesia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Hypospadias, Penile Torsion
Caudal vs. Pudendal Block in Peds GU
This study will compare two techniques to minimize pain during and after penile surgery in children undergoing certain urologic surgeries. These two approaches include the caudal nerve block and the pudendal nerve block.
- Conditions
- Hypospadias, Penile Torsion, Chordee, Phimosis
- Trial name
- NCT05708989
- Testing
- Caudal Block, Ultrasound-guided Pudendal Block, Injectable 1 ml/kg of 0.25% ropivacaine with 1mcg/kg dexmedetomidine
- Where
- United States
- Sponsor
- University Hospitals Cleveland Medical Center
Pain
SPRIX in 0 to 11 Year-Old Patients Undergoing Open Surgical Procedures
The purpose of this study is to evaluate the pharmacokinetics and safety of postoperative administration of SPRIX in pediatric patients (ages 0-11) undergoing open surgical procedures.
- Trial name
- NCT02102516
- Testing
- SPRIX(intranasal ketorolac tromethamine)
- Where
- 4 sites in Poland
- Volunteers
- 45 people
- Sponsor
- Egalet Ltd
Post Operative Pain
Dexametomedine Versus Ketamine as an Adjuvant in Erector Spinae Block for Perioperative Thoracotomy Pain Control
A double-blind randomized control study to compare the efficacy of dexmedetomidine versus ketamine as an adjuvant in combination with bupivacaine ultrasound-guided ESP block in patients scheduled for cardiothoracic surgeries with…
- Trial name
- NCT05552391
- Testing
- Bupivacaine, Ketamine Hydrochloride, Dexmedetomidine Hydrochloride
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Kasr El Aini Hospital
Post Operative Pain, Analgesia
Newborn Infant Parasympathetic Evaluation (NIPE) for Guiding Intraoperative Fentanyl in Children Under 2 Years
During general anesthesia, objective monitoring for analgesia is still lacking. The administration of opioids relies on the experience of the anesthesiologist.
- Conditions
- Post Operative Pain, Analgesia, Children, Only, Narcotic Use
- Trial name
- NCT05758090
- Testing
- NIPE monitor, Control
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Khon Kaen University
Fracture, Pain
Ibuprofen Versus Codeine. Is One Better for Post-operative Pain Relief Following Reduction of Paediatric Forearm Fractures?
For simple fractures treated in the emergency department with cast immobilisation only, ibuprofen has been shown to be superior to, or a least or equivalent to codeine with less side effects.
- Trial name
- NCT01605240
- Testing
- Acetaminophen and Ibuprofen, Acetaminophen and Codeine
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Appendicitis Acute
Surgical Site Infiltration Using Ketamine Versus Bupivacaine for Analgesia in Post-operative Appendectomy Operation
surgical site infiltration using ketamine versus Bupivacaine for analgesia in post-operative Appendectomy operation by Ketamine versus Bupivacaine
- Trial name
- NCT05097118
- Testing
- Ketamine Versus Bupivacaine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Post Operative Pain, Acute
A Study of Combogesic® 325 in Adolescent Patients With Moderate to Severe Postoperative Pain Associated With Orthopedic Surgery
Combogesic® 325 contains a combination of ibuprofen and acetaminophen. The purpose of this study is to compare the pain relief effects of Combogesic® 325mg and acetaminophen and to evaluate the safety of Combogesic® 325mg in…
- Trial name
- NCT07225140
- Testing
- Combogesic® tablets, Acetaminophen 500mg
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- AFT Pharmaceuticals, Ltd.
Pain, Postoperative
Innovative Approaches to Assessment of Pain Control and Sedation in the NICU
It is difficult to assess pain and agitation in the NICU population because for a multitude of reasons including the pre-verbal nature of the patient population, the atypical pain response of premature infants, and the use of…
- Trial name
- NCT03057782
- Testing
- Waveguard (TM) EEG cap, Micro Movement Sensor, Pico Movement Sensor
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston Children's Hospital