Clinical trials: Pre-myopia
Myopia, Pre-myopia
Early-Onset Myopia Intervention Project
The prevalence of myopia among children has been increasing year by year, which has become a globle public health issue. Studies have shown that defocusing lenses and atroping eyedrops can control the progression of myopia, but…
- Trial name
- EOM (NCT07176949)
- Testing
- 0.01% atropine eye drops, 0.05% atropine eye drops, Spectacle lenses with highly aspherical lenslets
- Where
- China
- Volunteers
- 508 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia, Pre-myopia
Virtual Far-sight Reading Device for Myopia Intervention Among Pre-myopic Children
This clinical trial wants to find out if the Virtual Far-sight Reading Device can help prevent or slow down myopia progression in children and teenagers with pre-myopia.
- Trial name
- NCT06995911
- Testing
- Virtual Far-sight Reading Device
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Comparing Relative Peripheral Refraction on Myopia Progression
The investigators will test our hypothesis that parameters on peripheral defocus can regulate eye growth: For instance, the relative peripheral refraction measured by Multispectral Refraction Topography (MRT) would be significant…
- Trial name
- CMPMRT (NCT06758843)
- Testing
- measure the axial length, visual acuity, and refraction at follow-up of 6- and 12-month
- Where
- China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Fuzhou Southeast Institute of Visual Ophthalmology
Pre-myopia
Evaluation of Contact Lenses and Myopia.
This study will evaluate the effect of dual focus contact lenses on Myopia prevention.
- Trial name
- NCT07566234
- Testing
- Test Lens - Dual Focus
- Where
- China
- Volunteers
- 110 people
- Sponsor
- CooperVision International Limited (CVIL)
Myopia
Refractive Error in Chinese Students
This cohort study aimed to assess the change of refractive status in Chinese school children.
- Trial name
- NCT05119543
- Testing
- outdoor time
- Where
- China
- Volunteers
- 36,452 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia, Myopia, Progressive
Myopia Progression With a Novel Extended Depth of Focus Contact Lens
Myopia has been increasing in prevalence and severity throughout the world over the last 30 years. Increasing levels of myopia are associated with increased frequencies and severity of various ocular pathologies, including…
- Trial name
- NCT03358862
- Testing
- NaturalVue Multifocal Contact Lens
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aller, Thomas A., OD
Myopic Children
A Randomized Clinical Trial on the Effectiveness of Novel Plano Spectacle Lenses on Myopia Prevention in Pre-myopic Children
Evaluate the efficacy, safety and wearing time compliance of novel plano spectacle lenses in delaying myopia onset in pre-myopic children and provide scientific basis for the development of myopia prevention strategies for…
- Trial name
- NCT06860737
- Testing
- Novel plano spectacle lenses
- Where
- China
- Volunteers
- 388 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Pre-myopia
PROTECT-Study: Prospective Research on Optimizing Atropine Concentration Escalation for Children's Myopia Prevention
A prospective multicenter study design was adopted. Children aged 6-9 years with premyopia who met the criteria were screened and administered after completion of baseline assessment. Phase I: 0-24 weeks (0-6M).
- Trial name
- PROTECT (NCT07449247)
- Testing
- 0.01% Atropine
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Eye Hospital
Myopia, Progressive
Low Concentration Atropine in the Prevention of Myopia in Children.
This double-blind, randomized controlled clinical study is to evaluate the effectiveness and safety of low concentration atropine in preventing myopia in pre-myopia children, and to explore whether there is a dose effect…
- Trial name
- NCT05939882
- Testing
- low concentration atropine (0.01%), low concentration atropine (0.02%), low concentration atropine (0.04%)
- Where
- China
- Volunteers
- 428 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Pre-myopia, Myopia
Managing Premyopia in Chinese Children Using Artificial Intelligence Assisted Defocus Incorporated Multiple Segments Based Spectacle Lens: a Randomized Controlled Clinical Trial
Pre-myopia refers to a condition in which children have not yet developed myopia but exhibit insufficient hyperopic reserve (≤ +0.75 D).
- Trial name
- NCT07765550
- Testing
- Artificial Intelligence Assisted DIMS based Spectacle Lens, Smartwatches
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Visual Developmental Disorders
Tertiary Care for Visual Developmental Disorders in Pre-school Children
Visual development disorders are major public health problems among children especially in China. How to find an effective and economic way to manage the larger number of children in China remains exploring.
- Trial name
- NCT03251456
- Testing
- Tertiary care, Usual Care
- Where
- China
- Volunteers
- 1,114 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia, Pre-myopia
A Pilot Evaluation of Refractive Error Progression in Pre-Myopic Children in Singapore With and Without Myopia Control Spectacles
This study aims to find out whether ZEISS MyoActive lenses can help prevent short-sightedness from developing in children. We aim to recruit at least 50 children in total for this study.
- Trial name
- NCT07779941
- Testing
- Zeiss MyoActive lenses, Single Vision Lenses
- Where
- Singapore
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre