Clinical trials: Pre-myopia
Myopia, Pre-myopia
Early-Onset Myopia Intervention Project
The prevalence of myopia among children has been increasing year by year, which has become a globle public health issue. Studies have shown that defocusing lenses and atroping eyedrops can control the progression of myopia, but…
- Trial name
- EOM (NCT07176949)
- Testing
- 0.01% atropine eye drops, 0.05% atropine eye drops, Spectacle lenses with highly aspherical lenslets
- Where
- China
- Volunteers
- 508 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia, Hyperopia
Subjective Comparison of Pre-Lens Tear Film Stability With Daily Disposable Contact Lenses
The purpose of this study was to compare three CE-marked daily disposable contact lenses for tear film stability as measured by pre-lens non-invasive keratograph break up time (PL NIK-BUT).
- Conditions
- Myopia, Hyperopia, Refractive Error
- Trial name
- NCT01839318
- Testing
- Nelfilcon A contact lenses, Omafilcon A contact lenses, Etafilcon A contact lenses
- Volunteers
- 30 people
- Sponsor
- Alcon Research
Myopia, Pre-myopia
Virtual Far-sight Reading Device for Myopia Intervention Among Pre-myopic Children
This clinical trial wants to find out if the Virtual Far-sight Reading Device can help prevent or slow down myopia progression in children and teenagers with pre-myopia.
- Trial name
- NCT06995911
- Testing
- Virtual Far-sight Reading Device
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Contact Lens Complication
The Impact of Soft Contact Lenses on the Corneal Neuromediators and Optical Quality in High Myopia Prior to SMILE
To investigate the influence of Neuromediators expression in corneal stromal lenticules and corneal injury repair after small incision extraction
- Trial name
- NCT06650306
- Testing
- This study does not involve any interventions
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- yuhao shao
Myopia
Daily Disposable Contact Lens Tear Film Study
The purpose of this study was to evaluate the pre-lens tear film stability of a new CE-marked daily disposable contact lens as compared to a commercially available daily disposable contact lens.
- Trial name
- NCT01473160
- Testing
- delefilcon A contact lens, narafilcon A contact lens
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- CIBA VISION
Myopia
Corneal WFG Versus AF Trans PRK in Myopic Patients With High Corneal HOA
compare the efficacy, safety and predictability of corneal wavefront guided (WFG) and aberration free ablation in single-step transepithelial photorefractive keratectomy (TransPRK) in myopic patients with high pre-existing…
- Trial name
- NCT03786861
- Testing
- corneal WFG group, aberration free group
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Myopia
Comparing Relative Peripheral Refraction on Myopia Progression
The investigators will test our hypothesis that parameters on peripheral defocus can regulate eye growth: For instance, the relative peripheral refraction measured by Multispectral Refraction Topography (MRT) would be significant…
- Trial name
- CMPMRT (NCT06758843)
- Testing
- measure the axial length, visual acuity, and refraction at follow-up of 6- and 12-month
- Where
- China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Fuzhou Southeast Institute of Visual Ophthalmology
Pre-myopia
Evaluation of Contact Lenses and Myopia.
This study will evaluate the effect of dual focus contact lenses on Myopia prevention.
- Trial name
- NCT07566234
- Testing
- Test Lens - Dual Focus
- Where
- China
- Volunteers
- 110 people
- Sponsor
- CooperVision International Limited (CVIL)
Myopia
The Accuracy of Flap Thickness Versus the Pre-determined Surgical Planning Using WaveLight® FS200
The objective is to evaluate the resultant thickness of the FS200 created LASIK flap compared to plan at the surgical visit.
- Trial name
- NCT05501795
- Testing
- WaveLight® FS200 femtosecond laser
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Stephen Wexler
Presbyopia
A Prospective Study to Evaluate the Raindrop Near Vision Inlay in Presbyopic Patients With Treatments to Optimize the Ocular Surface Before Implantation
The objective of this study is to evaluate the Raindrop® Near Vision Inlay for the improvement of near vision in presbyopic patients with treatments to optimize the ocular surface before corneal inlay surgery.
- Trial name
- NCT03126877
- Testing
- Mitomycin C, Raindrop Near Vision Inlay
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Whitten Laser Eye
Myopia
Refractive Error in Chinese Students
This cohort study aimed to assess the change of refractive status in Chinese school children.
- Trial name
- NCT05119543
- Testing
- outdoor time
- Where
- China
- Volunteers
- 36,452 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia, Myopia, Progressive
Myopia Progression With a Novel Extended Depth of Focus Contact Lens
Myopia has been increasing in prevalence and severity throughout the world over the last 30 years. Increasing levels of myopia are associated with increased frequencies and severity of various ocular pathologies, including…
- Trial name
- NCT03358862
- Testing
- NaturalVue Multifocal Contact Lens
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aller, Thomas A., OD
Myopic Children
A Randomized Clinical Trial on the Effectiveness of Novel Plano Spectacle Lenses on Myopia Prevention in Pre-myopic Children
Evaluate the efficacy, safety and wearing time compliance of novel plano spectacle lenses in delaying myopia onset in pre-myopic children and provide scientific basis for the development of myopia prevention strategies for…
- Trial name
- NCT06860737
- Testing
- Novel plano spectacle lenses
- Where
- China
- Volunteers
- 388 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Cornea, Refractive Surgery
Evaluation of the Effect of Myopic Femtosecond Laser Assisted-LASIK on Anterior Chamber Flare Values and Corneal Endothelial Cells: A Prospective Before-and-After Study
This study aimed to investigate whether femtosecond laser-assisted LASIK (FS-LASIK) surgery causes inflammation in the anterior chamber and to analyze its effect on endothelial cells.
- Conditions
- Cornea, Refractive Surgery, Anterior Chamber Inflammation
- Trial name
- NCT04899258
- Testing
- Femtosecond laser assisted LASIK
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Keratomileusis, Laser In Situ
The Role of Psychosocial and Other Quality of Life Parameters in Evaluating Functional Changes Prior to and Following Laser In-situ Keratomileusis (LASIK)Changes Laser In-situ Keratomileusis (LASIK)
To evaluate the changes in quality of life parameters after LASIK surgery.
- Trial name
- NCT00344604
- Testing
- Role of psychosocial and quality of life parameters prior to and following LASIK.
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Pre-myopia
PROTECT-Study: Prospective Research on Optimizing Atropine Concentration Escalation for Children's Myopia Prevention
A prospective multicenter study design was adopted. Children aged 6-9 years with premyopia who met the criteria were screened and administered after completion of baseline assessment. Phase I: 0-24 weeks (0-6M).
- Trial name
- PROTECT (NCT07449247)
- Testing
- 0.01% Atropine
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Eye Hospital
Postoperative Visual Outcomes Following Cataract Surgery in Patients With Prior Myopic Corneal Laser Vision Correction
Evaluation of Cataract Surgery Outcomes in Patients With Prior Laser Vision Correction Implanted With the CT LUCIA Lens
This is a prospective, Phase IV, post-approval observational study evaluating postoperative outcomes in patients with a history of myopic corneal laser vision correction (LVC) undergoing bilateral cataract surgery with…
- Trial name
- NCT07084545
- Testing
- CT LUCIA 621P Intraocular Lens Implantation
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Carl Zeiss Meditec AG
Myopia, Progressive
Low Concentration Atropine in the Prevention of Myopia in Children.
This double-blind, randomized controlled clinical study is to evaluate the effectiveness and safety of low concentration atropine in preventing myopia in pre-myopia children, and to explore whether there is a dose effect…
- Trial name
- NCT05939882
- Testing
- low concentration atropine (0.01%), low concentration atropine (0.02%), low concentration atropine (0.04%)
- Where
- China
- Volunteers
- 428 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Age-Related Macular Degeneration, Branch Retinal Vein Occlusion With Macular Edema
A Study to Evaluate the Usability of the SB11 PFS in Trial Participants With Wet AMD, Macular Oedema Secondary to RVO, or mCNV
This is a open label, multicenter, Phase II study to evaluate the usability of the pre-filled syringe (PFS) of SB11 (ranibizumab biosimilar).
- Conditions
- Age-Related Macular Degeneration, Branch Retinal Vein Occlusion With Macular Edema, Central Retinal Vein Occlusion With Macular Edema, Myopic Choroidal Neovascularization
- Trial name
- NCT07550504
- Testing
- SB11 PFS
- Where
- 2 sites in Poland
- Volunteers
- 30 people
- Sponsor
- Samsung Bioepis Co., Ltd.
Pre-myopia, Myopia
Managing Premyopia in Chinese Children Using Artificial Intelligence Assisted Defocus Incorporated Multiple Segments Based Spectacle Lens: a Randomized Controlled Clinical Trial
Pre-myopia refers to a condition in which children have not yet developed myopia but exhibit insufficient hyperopic reserve (≤ +0.75 D).
- Trial name
- NCT07765550
- Testing
- Artificial Intelligence Assisted DIMS based Spectacle Lens, Smartwatches
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center