Clinical trials: Prediction
Strep Throat, Pneumonia
Integrated Clinical Prediction Rules: Bringing Evidence to Diverse Primary Care Settings
The study is a randomized controlled trial, with an Intervention Group and a Control Group at the University of Utah (U of U) and University of Wisconsin (UW). BU serves as the primary award and coordinating institution.
- Trial name
- iCPR2 (NCT02534987)
- Testing
- iCPR2
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- NYU Langone Health
Type 1 Diabetes Mellitus
Molecular Quantification of Insulin mRNA
The objectives of this study are to: 1. quantitate the level of insulin mRNA in the while cell fraction of whole blood in selected groups of subjects, 2.
- Trial name
- NCT00324207
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Appendicitis
Diagnostic Accuracy of Serum Bilirubin in the Prediction of Perforated Appendicitis
Hyperbilirubinemia is reported to be a positive predictor in diagnosing perforated appendicitis. Therefore we analysed the diagnostic accuracy of serum bilirubin in discriminating between perforated and simple/no appendicitis.
- Trial name
- NCT01698099
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- University Hospital Tuebingen
Liver Transplantation
A New Prediction Mode for Predicting the Risk of Pressure Injury in Patients Undergoing Liver Transplantation
Pediatric population is at a high-risk of pressure injury (PI). Patients undergoing liver transplantation are more prone to PIs compared with other types of surgery.
- Trial name
- PMPRPIULT (NCT05588271)
- Testing
- Exposures
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Knee Arthropathy, Hip Arthropathy
Analysis of Influencing Factors and Construction of Prediction Models of Artificial Joint Replacement in China
The project intends to analyze the epidemiological characteristics, risk factors, complications and resource utilization of artificial joint replacement in China through the inpatient data collected by the Hospital Quality…
- Conditions
- Knee Arthropathy, Hip Arthropathy, Shoulder Arthropathy, Ankle Arthropathy
- Trial name
- NCT05170321
- Where
- China
- Volunteers
- 600,000 people
- Sponsor
- Xiangya Hospital of Central South University
Crohn Disease
Prediction and Close Monitoring of Postoperative Recurrence by Intestinal Ultrasound After Ileocecal Resection in Crohn's Disease Patients
Crohn's disease (CD) is an inflammatory bowel disease causing chronic transmural inflammation followed by intestinal complications including strictures and penetrating lesions such as fistulas and abscesses.
- Trial name
- INSIGHT (NCT05713409)
- Testing
- Intestinal ultrasound
- Where
- 5 sites in Germany, Italy and 2 more
- Volunteers
- 120 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Recurrent Lumbar Disc Herniation
The Prediction of Recurrence Lumbar Disc Herniation At L5-S1 Level Through Machine Learning Models Based on Endoscopic Discectomy Via the Interlaminar Approach
What Was the Study About? This study focused on improving the care of patients with a specific type of back problem called lumbar disc herniation at the L5-S1 level.
- Trial name
- NCT06833099
- Testing
- VAS Point and Imaging Examination
- Where
- China
- Volunteers
- 309 people
- Sponsor
- Jinyu Chen
Cesarean Section Complications, Postpartum Hemorrhage
Obstetric Comorbidity Index in Postpartum Hemorrhage
The objective of this study is to examine the predictive capability of the Obstetric comorbidity index in the identification of severe maternal morbidity associated with postpartum hemorrhage in patients undergoing cesarean…
- Conditions
- Cesarean Section Complications, Postpartum Hemorrhage, Morbidity;Perinatal
- Trial name
- NCT06431204
- Testing
- Obstetric comorbidity index
- Where
- Thailand
- Volunteers
- 583 people
- Sponsor
- Mahidol University
Brain Injuries, Pulmonary Embolism
Improving the Stewardship of Diagnostic Imaging Resources in Alberta Emergency Departments
Utilization of diagnostic imaging in the Emergency Department has increased dramatically over the past two decades, driven by an increased availability of advanced imaging, legal pressures to exclude serious diagnoses in low-risk…
- Trial name
- NCT02410941
- Testing
- Clinical decision support
- Where
- 16 sites in Canada
- Volunteers
- 52,058 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Developmental Language Disorder
Sentence Prediction in Developmental Language Disorder
Millions of children - 7-12% of the school-age population - have developmental language disorder (DLD), a disorder that affects language learning, comprehension, and use.
- Trial name
- NCT07510854
- Testing
- Thematic role, Sentence complexity
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home
Patients With Locally Advanced Carcinoma of the Stomach and Oesophagogastric Junction
Radiomics-based Models for the Prediction of Pathological Response to Neoadjuvant Therapy in Gastric and Gastroesophageal Cancer
Identifying predictors of response to neoadjuvant therapy in gastric and gastro-oesophageal cancer early in the history of the disease would ensure optimal treatment planning.
- Trial name
- RADI-S (NCT06044961)
- Testing
- CT scan
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Schizophrenia, Psychotic Disorders
Enhancing the Prospective Prediction of Psychosis
This study will gather information on the natural history of the basic symptoms of psychosis to identify factors that may affect the improvement or persistence of the symptoms.
- Trial name
- NCT00291200
- Where
- 3 sites in United States, Canada
- Volunteers
- 268 people
- Sponsor
- Yale University
Crohn Disease
Early MRI Prediction of Crohns
The investigators plan a prospective study designed to optimize and translate noncontrast, novel Magnetic Resonance Imaging (MRI) techniques for detecting and measuring intestinal inflammation as well as for allowing early…
- Trial name
- NCT03340519
- Testing
- MR Imaging
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Melanoma (Skin Cancer), Artificial Intelligence (AI)
Artificial Intelligence Based Melanoma Early Diagnosis and Risk Prediction in Children, Adolescents and Young Adults
The goal of this study is to develop supportive diagnostic artificial intelligence algorithms to distinguish melanoma from nevi or other benign pigmented skin lesions, especially in younger patients (below the age of 30).
- Conditions
- Melanoma (Skin Cancer), Artificial Intelligence (AI), Pediatric Cancer
- Trial name
- AI-MEL (NCT06621810)
- Where
- 3 sites in Germany, Italy and 1 more
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- German Cancer Research Center
Child, Cerebral Palsy
Prevention of Hip Displacement in Children With Cerebral Palsy in Denmark
Children with cerebral palsy have an increased risk of hip dislocation, which is a painful and severe complication of cerebral palsy.
- Conditions
- Child, Cerebral Palsy, Radiography, Hip Dislocation
- Trial name
- NCT04403178
- Testing
- Radiographic examination with a Migration of > 40 %
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Mette Røn Kristensen
Autoimmune Hepatitis
Machine Learning for Prediction of Therapy Response in Autoimmune Hepatitis
The 5th International Autoimmune Hepatitis Group (IAIHG) research workshop emphasized the integration of large clinical cohorts with artificial intelligence (AI) for enhanced prediction of therapy responses and outcomes in…
- Trial name
- NCT07378202
- Where
- 2 sites in Germany
- Volunteers
- 5,000 people
- Sponsor
- Hannover Medical School
Sepsis
Smart Discharges for Older Children
This study is an observational multi-country cohort study that aims to build algorithms that can identify children between 5 and 16 years of age admitted for proven or suspected sepsis who are at risk of mortality after they are…
- Trial name
- NCT07629154
- Testing
- No Intervention: Observational Cohort
- Where
- 7 sites in United States, Canada and 3 more
- Volunteers
- 4,000 people
- Sponsor
- University of British Columbia
Mild Traumatic Brain Injury
BLOOD BIOMARKERS in PAEDIATRIC MTBI
The goal of this observational study is to identify blood biomarkers that could help in the management of paediatric patients with mild TBI. The main questions it aims to answer are: 1.
- Trial name
- t-BIOMAP (NCT06233851)
- Where
- Switzerland
- Volunteers
- 600 people
- Sponsor
- Pediatric Clinical Research Platform
Wounds and Injuries
Transferability of Clinical Prediction Models for Early Trauma Care in a Swedish Setting
Trauma is one of the top threats to population health globally. A substantial body of research has been devoted to the development of clinical prediction models to aid early decision making in trauma care.
- Trial name
- NCT02940678
- Testing
- No intervention
- Volunteers
- 26,965 people
- Sponsor
- Karolinska Institutet
Pancreatic Masses
Diagnostic Prediction of Pancreatic Masses
The goal of this observational study is to learn if a strategy can be developed for differentiating autoimmune pancreatitis (AIP) and primary pancreatic lymphoma (PPL) from pancreatic ductal adenocarcinoma (PDAC) in patients…
- Trial name
- NCT06724055
- Volunteers
- 110 people
- Sponsor
- Peking Union Medical College Hospital