Clinical trials: Pregnancy, Puerperium and Perinatal Conditions
Sepsis, Pneumonia
Improved Accessibility of EmONC Services for Maternal and Newborn Health: a Community Based Project
The purpose of this study is to determine whether an integrated EmONC package (community mobilization, training of community-based health care providers and a maternal and neonatal health pack) reduce perinatal and neonatal…
- Conditions
- Sepsis, Pneumonia, Omphalitis, Birth Asphyxia
- Trial name
- EmONC (NCT01751945)
- Testing
- EmONC package
- Where
- Pakistan
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Obesity, Pregnancy Related
Optimizing Health From Pregnancy Through One Year Postpartum
This study will evaluate the impact of different combinations of intervention as a function of gestational weight gain in pregnant woman. Participants will be randomized at two points during the study.
- Trial name
- HABIT (NCT03069690)
- Testing
- HABITpreg, HABITpost
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- University of Pittsburgh
Maternal Death, Neonatal Death
Evaluating the Effects of SMS Text Messaging Support System Among Frontline Health Workers in Ghana
Introduction Maternal and neonatal mortality continue to be to be prominent public health issues in sub Saharan Africa including Ghana, with slow progress made towards attainment of Millennium Development Goals (MDG) 4 \& 5.
- Conditions
- Maternal Death, Neonatal Death, Postpartum Haemorrhage, Pre-eclampsia
- Trial name
- Accelerate (NCT02468310)
- Testing
- Maternal and neonatal emergency protocols
- Where
- Ghana
- Volunteers
- 65,831 people, healthy volunteers welcome
- Sponsor
- Hannah Brown Amoakoh
Perinatal Mental Health, Gestational Weight Gain
Healthy Adaptation to Pregnancy, Postpartum and Parenthood
Healthy Adaptation to Pregnancy, Postpartum and Parenthood (HAP3) The HAP3 study is evaluating a new digital support program for pregnant women and their partners.
- Conditions
- Perinatal Mental Health, Gestational Weight Gain, Postpartum Weight Retention, Child Development
- Trial name
- HAP3 (NCT07837193)
- Testing
- HAP3 Family App
- Where
- Belgium
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Obstetric and Perinatal Complications, Postpartum Hemorrhage
A Skills and Drills Intervention for Emergency Obstetrics and Neonatal Care at First Referral Units of North Karnataka
To evaluate the effectiveness of a First Referral Unit (FRU) Emergency Obstetric and Newborn Care (EmONC) skills and drills intervention, to estimate the appropriateness and effectiveness of referrals in intervention arm compared…
- Conditions
- Obstetric and Perinatal Complications, Postpartum Hemorrhage, Preeclampsia/Eclampsia, Obstructed/Prolonged Labor
- Trial name
- NCT01865656
- Testing
- Skills training, Emergency obstetric drills, Revised Case Sheets
- Volunteers
- 15,018 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
COVID19, Coronavirus Infection
Northeast COVID-19 and Pregnancy Study Group
A prospective and retrospective cohort study. The objective will to determine the frequency of COVID-19 in pregnant and postpartum women hospitalized with flu syndrome, to evaluate clinical and laboratory predictors of COVID-19…
- Conditions
- COVID19, Coronavirus Infection, Pregnancy Disease, Severe Acute Respiratory Syndrome
- Trial name
- NCOVIP (NCT04462367)
- Where
- Brazil
- Volunteers
- 180 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Postpartum Infection
Trends in Pregnancy Outcomes Beyond Twenty Weeks Gestational Age in Assisted Reproductive Technology Conceived Pregnancies in British Columbia
Examining outcomes beyond 20 weeks gestational age in pregnancies conceived by ART compared to spontaneously conceived pregnancies 1.
- Trial name
- NCT06726603
- Testing
- Assisted Reproductive Technology
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Maternal Sepsis During Labor, Hemorrhage, Postpartum
Scaling Up an Integrated Approach to Improve Delivery Care in North Guatemala With Stepped Wedge Design
"¡Que Vivan las Madres!: Venga a tener su parto al CAP" (QVLM) is a guatemalan quasi-experimental study that has been performed from January 2014 to January 2017 by the Epidemiological Research Center in Sexual and Reproductive…
- Conditions
- Maternal Sepsis During Labor, Hemorrhage, Postpartum, Eclampsia; Complicating Pregnancy, Pre-Eclampsia
- Trial name
- QVLM (NCT03151070)
- Testing
- QVLM Intervention package
- Volunteers
- 32,000 people
- Sponsor
- Hospital San Juan de Dios Guatemala
Cesarean Section Complications, Postpartum Hemorrhage
Obstetric Comorbidity Index in Postpartum Hemorrhage
The objective of this study is to examine the predictive capability of the Obstetric comorbidity index in the identification of severe maternal morbidity associated with postpartum hemorrhage in patients undergoing cesarean…
- Conditions
- Cesarean Section Complications, Postpartum Hemorrhage, Morbidity;Perinatal
- Trial name
- NCT06431204
- Testing
- Obstetric comorbidity index
- Where
- Thailand
- Volunteers
- 583 people
- Sponsor
- Mahidol University
Post Partum Haemorrhage
Severe Post Partum Haemorrhage (PPH): A Randomized Trial on Transversal Intervention in 6 French Perinatal Networks
Hypothesis A "multifaceted" intervention program aimed at increasing the responsiveness of care givers, the adequacy of care provided, and the efficacy of organisation of care, in presence of abnormal blood loss in the immediate…
- Trial name
- NCT00344929
- Where
- France
- Volunteers
- 6,500 people
- Sponsor
- Hospices Civils de Lyon
Pregnancy, Puerperium and Perinatal Conditions
The Pediatric Development Clinic Study
Many preterm, low birth weight and other high-risk infants are surviving the early neonatal period. However, upon discharge from the neonatal units, this at-risk population has little support for their health, nutrition and…
- Trial name
- PDC (NCT03665012)
- Testing
- Pediatric Development Clinic (PDC)
- Where
- Rwanda
- Volunteers
- 376 people
- Sponsor
- Partners in Health
Infant, Newborn, Diseases, Sepsis
Prevention of Perinatal Sepsis (PoPS): Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn
The purpose of this study is to evaluate whether use of the disinfectant chlorhexidine administered to the birth canal during labour and newborn at delivery can protect a woman and her baby from bacterial infections after birth.
- Conditions
- Infant, Newborn, Diseases, Sepsis, Puerperal Infection
- Trial name
- NCT00136370
- Testing
- Chlorhexidine, Birth canal wipe, sterile water external genital wipe
- Where
- South Africa
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Pregnancy
Cluster-randomized Trial Measuring Integration of Professional Midwives and Obstetric Nurses in Rural Clinics in Mexico
Rates and causes of maternal mortality in Mexico have dropped only slightly; thus, reaching the internationally established Millennium Development Milestones (MDM) is still a distant goal.
- Trial name
- NCT01477541
- Testing
- PM/ON integration
- Volunteers
- 27 people
- Sponsor
- Instituto Nacional de Salud Publica, Mexico
Postpartum Hemorrhage, Delivery Complication
Trends in the Administration of Tranexamic Acid for Postpartum Hemorrhage
Postpartum hemorrhage (PPH) is the global leading cause of maternal death, with 20-30% of maternal deaths in Thailand linked to hemorrhage.
- Conditions
- Postpartum Hemorrhage, Delivery Complication, Cesarean Section Complications, Perinatal Problems
- Trial name
- NCT07278037
- Testing
- Tranexamic acid
- Where
- Thailand
- Volunteers
- 648 people
- Sponsor
- Mahidol University