Clinical trials: Pregnancy, Puerperium and Perinatal Conditions
Postpartum Depression, Postpartum Anxiety
The Maternal Well-Being Study
This project aims to understand the local feasibility and acceptability of MamaMeals (a home-delivered nutritious, postpartum meal delivery program) and MamaMatters (a moderated social media-based peer support group) among…
- Conditions
- Postpartum Depression, Postpartum Anxiety, Weight Retention, Postpartum, Nutritional and Metabolic Diseases
- Trial name
- MWB (NCT05484999)
- Testing
- Meals, Meals + Social Support, Control
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Depression, Postpartum, Pregnancy
Labor Pain and Postpartum Behavioral Health Outcomes Study
In this pilot prospective longitudinal observational study, women who are pregnant and who will be experiencing childbirth for the first time will be recruited at the third trimester and observed longitudinally for psychiatric…
- Conditions
- Depression, Postpartum, Pregnancy, Child Development, Pain
- Trial name
- LPPD (NCT02692404)
- Where
- 2 sites in United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Weight Stigma
Adapting a Health at Every Size Intervention to Obstetric Care
Perinatal mental health disorders occur in 1 in 5 pregnancies and have significant negative intergenerational consequences including being the leading cause of overall and preventable mortality during pregnancy and the first year…
- Trial name
- OB-HAES (NCT06919783)
- Testing
- Health at Every Size in Obstetrics
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Massachusetts, Worcester
Pregnancy, Puerperium and Perinatal Conditions
The Pediatric Development Clinic Study
Many preterm, low birth weight and other high-risk infants are surviving the early neonatal period. However, upon discharge from the neonatal units, this at-risk population has little support for their health, nutrition and…
- Trial name
- PDC (NCT03665012)
- Testing
- Pediatric Development Clinic (PDC)
- Where
- Rwanda
- Volunteers
- 376 people
- Sponsor
- Partners in Health
COVID19, Coronavirus Infection
Northeast COVID-19 and Pregnancy Study Group
A prospective and retrospective cohort study. The objective will to determine the frequency of COVID-19 in pregnant and postpartum women hospitalized with flu syndrome, to evaluate clinical and laboratory predictors of COVID-19…
- Conditions
- COVID19, Coronavirus Infection, Pregnancy Disease, Severe Acute Respiratory Syndrome
- Trial name
- NCOVIP (NCT04462367)
- Where
- Brazil
- Volunteers
- 180 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Sleep, Postpartum Depression
The Dream Team: Testing Implementation of a Sleep Intervention for Perinatal Women Delivered by Direct Care Workers
Insufficient and disrupted sleep are rarely addressed in expectant and new mothers, despite evidence that disturbed sleep is a modifiable risk factor for negative health outcomes for mothers and their children.
- Conditions
- Sleep, Postpartum Depression, Pregnancy Related, Insomnia
- Trial name
- NCT06737055
- Testing
- Education about behavioral strategies to improve sleep
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Depression and Suicide, Mood Disorders
Biological Triggers of Depression in Pregnancy
The goal of the study is to define and measure biological processes that contribute to the underlying pathophysiologic process of peri-partum depression to be used for identifying those at risk for developing it.
- Conditions
- Depression and Suicide, Mood Disorders, Other Perinatal Conditions
- Trial name
- NCT02566980
- Where
- 3 sites in United States
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Cesarean Section Complications, Postpartum Hemorrhage
Obstetric Comorbidity Index in Postpartum Hemorrhage
The objective of this study is to examine the predictive capability of the Obstetric comorbidity index in the identification of severe maternal morbidity associated with postpartum hemorrhage in patients undergoing cesarean…
- Conditions
- Cesarean Section Complications, Postpartum Hemorrhage, Morbidity;Perinatal
- Trial name
- NCT06431204
- Testing
- Obstetric comorbidity index
- Where
- Thailand
- Volunteers
- 583 people
- Sponsor
- Mahidol University
Maternal Death, Neonatal Death
Evaluating the Effects of SMS Text Messaging Support System Among Frontline Health Workers in Ghana
Introduction Maternal and neonatal mortality continue to be to be prominent public health issues in sub Saharan Africa including Ghana, with slow progress made towards attainment of Millennium Development Goals (MDG) 4 \& 5.
- Conditions
- Maternal Death, Neonatal Death, Postpartum Haemorrhage, Pre-eclampsia
- Trial name
- Accelerate (NCT02468310)
- Testing
- Maternal and neonatal emergency protocols
- Where
- Ghana
- Volunteers
- 65,831 people, healthy volunteers welcome
- Sponsor
- Hannah Brown Amoakoh
Postnatal Depression, Genetic Predisposition
Sequence Variations of Genes in the Estrogen Pathway and Perinatal Depression
To elucidate the disease pathway of perinatal depression by identifying genetic variants which could play a role in predisposing to the condition and/or lead to better understanding of the pathogenesis of the condition.
- Trial name
- NCT02373709
- Where
- Singapore
- Volunteers
- 750 people
- Sponsor
- KK Women's and Children's Hospital
Infectious Disease, Neoplasms
AnovaOS Network Powered Patient Registry
The objective of this study is the development, implementation and management of a registry of patient data that captures clinically meaningful, real-world, data on the diagnosis, nature, course of infection, treatment(s) and…
- Conditions
- Infectious Disease, Neoplasms, Diseases of the Blood and Blood-Forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89), Endocrine, Nutritional and Metabolic Diseases (E00-E89)
- Trial name
- NCT05013944
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Anova Enterprises, Inc
Maternal Sepsis During Labor, Hemorrhage, Postpartum
Scaling Up an Integrated Approach to Improve Delivery Care in North Guatemala With Stepped Wedge Design
"¡Que Vivan las Madres!: Venga a tener su parto al CAP" (QVLM) is a guatemalan quasi-experimental study that has been performed from January 2014 to January 2017 by the Epidemiological Research Center in Sexual and Reproductive…
- Conditions
- Maternal Sepsis During Labor, Hemorrhage, Postpartum, Eclampsia; Complicating Pregnancy, Pre-Eclampsia
- Trial name
- QVLM (NCT03151070)
- Testing
- QVLM Intervention package
- Volunteers
- 32,000 people
- Sponsor
- Hospital San Juan de Dios Guatemala
Post Partum Haemorrhage
Severe Post Partum Haemorrhage (PPH): A Randomized Trial on Transversal Intervention in 6 French Perinatal Networks
Hypothesis A "multifaceted" intervention program aimed at increasing the responsiveness of care givers, the adequacy of care provided, and the efficacy of organisation of care, in presence of abnormal blood loss in the immediate…
- Trial name
- NCT00344929
- Where
- France
- Volunteers
- 6,500 people
- Sponsor
- Hospices Civils de Lyon
Sepsis, Pneumonia
Improved Accessibility of EmONC Services for Maternal and Newborn Health: a Community Based Project
The purpose of this study is to determine whether an integrated EmONC package (community mobilization, training of community-based health care providers and a maternal and neonatal health pack) reduce perinatal and neonatal…
- Conditions
- Sepsis, Pneumonia, Omphalitis, Birth Asphyxia
- Trial name
- EmONC (NCT01751945)
- Testing
- EmONC package
- Where
- Pakistan
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Perinatal Mental Health, Gestational Weight Gain
Healthy Adaptation to Pregnancy, Postpartum and Parenthood
Healthy Adaptation to Pregnancy, Postpartum and Parenthood (HAP3) The HAP3 study is evaluating a new digital support program for pregnant women and their partners.
- Conditions
- Perinatal Mental Health, Gestational Weight Gain, Postpartum Weight Retention, Child Development
- Trial name
- HAP3 (NCT07837193)
- Testing
- HAP3 Family App
- Where
- Belgium
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Postpartum Depression, Pregnancy Related
Clinical Pilates and Prenatal Education on Perinatal Depressive Symptoms
This study evaluated whether a combined program of supervised Clinical Pilates Exercise and structured Prenatal Education, added to routine antenatal care, reduces perinatal depressive symptoms compared with routine antenatal…
- Conditions
- Postpartum Depression, Pregnancy Related, Low Back Pain, Labor Pain
- Trial name
- CPE-PE (NCT07647809)
- Testing
- Clinical Pilates Exercise, Prenatal Education
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Postpartum Hemorrhage, Delivery Complication
Trends in the Administration of Tranexamic Acid for Postpartum Hemorrhage
Postpartum hemorrhage (PPH) is the global leading cause of maternal death, with 20-30% of maternal deaths in Thailand linked to hemorrhage.
- Conditions
- Postpartum Hemorrhage, Delivery Complication, Cesarean Section Complications, Perinatal Problems
- Trial name
- NCT07278037
- Testing
- Tranexamic acid
- Where
- Thailand
- Volunteers
- 648 people
- Sponsor
- Mahidol University
Obesity, Pregnancy Related
Optimizing Health From Pregnancy Through One Year Postpartum
This study will evaluate the impact of different combinations of intervention as a function of gestational weight gain in pregnant woman. Participants will be randomized at two points during the study.
- Trial name
- HABIT (NCT03069690)
- Testing
- HABITpreg, HABITpost
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- University of Pittsburgh
Perinatal and Postpartum Anal Incontinence
Reducing Perinatal Anal Incontinence Through Early Pelvic Floor Muscle Training: a Prospective Pilot Study
Anal incontinence affects up to 20% of gravid women during and immediately after pregnancy. It can lead to embarrassment, poor self-image, lifestyle changes, in addition to poor hygiene and increased risk for genitourinary tract…
- Trial name
- NCT02270008
- Testing
- Pelvic floor training
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Emory University
Vaginal Delivery, Surgical Site Infection
Skip Prep of Vaginal Delivery to Prevent Puerperal / Perinatal Infection in Vaginal Delivery
This is a multi-center, randomized, controlled trial study to find whether use of chlorhexidine-alcohol or povidone-iodine for pre-vaginal delivery skin prep is superior to reduce postpartum infection in pregnant women with…
- Trial name
- NCT05122169
- Testing
- Povidone-Iodine, Chlorhexidine
- Volunteers
- 4,140 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital