Clinical trials: Preterm Labor With Preterm Delivery
Prematurity; Extreme, Prematurity; Decision Support
Health-Related Quality-of-Life and Household Financial and Wellbeing Impacts of Prematurity and Necrotising Enterocolitis (NEC).
PREM-IMPACT is a UK-based observational study exploring how caring for a very premature baby-particularly one affected by necrotising enterocolitis (NEC)-impacts families over the first year after hospital discharge.
- Conditions
- Prematurity; Extreme, Prematurity; Decision Support, Necrotising Enterocolitis, Preterm
- Trial name
- PREM-IMPACT (NCT07192393)
- Where
- 7 sites in United Kingdom
- Volunteers
- 90 people
- Sponsor
- Imperial College London
Necrotizing Enterocolitis, Allergy
Investigation of Allergen Sensitization in Newborn Babies Diagnosed With Necrotizing Enterocolitis.
To evaluate the frequency of allergy between 12 and 24 months of age in infants who were treated in the neonatal clinic and had NEC.
- Conditions
- Necrotizing Enterocolitis, Allergy, Preterm
- Trial name
- AlisNEC (NCT07562009)
- Testing
- skin prick test
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Feeding Behavior, Mother-Child Relations
Examining the Effect of Occupational Therapy-Based Parent Coaching on Feeding Problems in Children With a Preterm Birth
Feeding problems are common in children with a history of premature birth, and these problems continue into early childhood. Feeding problems are affected by many biopsychosocial factors, and the context in which feeding takes…
- Conditions
- Feeding Behavior, Mother-Child Relations, Feeding and Eating Disorders
- Trial name
- NCT06266507
- Testing
- Ergotherapy Based Parent Coaching, Informative Brochure Distribution
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Preterm Infant
Effects of Parenteral Nutrition With Different Lipid Emulsions in Preterm Infants
Previous studies have suggested that olive oil-based emulsion is safe and well tolerated in preterm infants, a showed efficacy and a good clinical and biological safety profile.
- Trial name
- NCT01683162
- Testing
- ClinOleic, Lipofundin, Intralipid
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Wei Cai
Feeding Intolerance in Preterm, NEC
Non-Invasive Prediction of Necrotizing Enterocolitis in Preterm Neonates with Feeding Intolerance Using Fecal Lipocalin-2 and Electrical Cardiometry
Prospective observational study to evaluate the efficiency of using electrical cardiometry in combination with fecal lipocalin-2 for prediction of NEC in preterm neonates with feeding intolerance
- Conditions
- Feeding Intolerance in Preterm, NEC, Electrical Cardiometry, PreTerm Neonate
- Trial name
- NCT06874153
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Ain Shams University
Cerebral Oxygenation, Cerebral Blood Flow
Cerebral Near Infrared Spectroscopy During Blood Sampling From a Peripheral Artery Catheter in Preterm Infants
Preterm infants often need peripheral artery catheters for invasive blood pressure recording and to facilitate blood sampling. Near infrared spectroscopy is a method to evaluate cerebral oxygenation and as well as cerebral blood…
- Conditions
- Cerebral Oxygenation, Cerebral Blood Flow, Prematurity
- Trial name
- NCT00926770
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Cologne
Neonatal Respiratory Distress, Preterm Birth
Study of the Feasibility of Early Lung Ultrasound in Neonatal Respiratory Distress in Premature Newborns Born Between 32 Weeks of Amenorrhea and 36 Weeks Plus 6 Days of Amenorrhea, Hospitalized in the Neonatal Pediatrics and Intensive Care Units of the Dijon University Hospital
Monocentric study carried out in the Neonatal and Intensive Care Units of the Dijon University Hospital. The objective is to evaluate the feasibility of performing a pulmonary ultrasound within 6 hours after admission in…
- Trial name
- REchoPP (NCT05737095)
- Testing
- Pulmonary ultrasound
- Where
- France
- Volunteers
- 69 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Bronchopulmonary Dysplasia
Early Prediction of Bronchopulmonary Dysplasia in Preterm Infants Using Clinical Data
Early Prediction of Bronchopulmonary Dysplasia in Preterm Infants Using Clinical Data from the First Three Postnatal Weeks with Large Language Models: A Retrospective Study This retrospective, observational study aims to evaluate…
- Trial name
- NCT07525167
- Testing
- Artificial Intelligence-Based Risk Prediction
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Konya City Hospital
Adrenal Insufficiency
Relative Adrenal Insufficiency in Preterm Very Low Birth Weight Infants With Shock
The objective of this study is to estimate the prevalence of relative adrenal insufficiency in preterm very low birth weight infants with and without shock.
- Trial name
- NCT00974337
- Where
- India
- Volunteers
- 39 people
- Sponsor
- All India Institute of Medical Sciences
Neonatal Respiratory Distress Syndrome, Inflammatory Response
Assessment Of Dose-Dependent Immunomodulatory Effect Of Alveofact With or Without Steroisd In Neonatal RDS
An Exploratory Randomized double-arm controlled trial to evaluate the immunomodulatory effect of low versus high dose of Alveofact with or without Budesonide.
- Conditions
- Neonatal Respiratory Distress Syndrome, Inflammatory Response, Premature Lungs, Neutrophil Extracellular Trap Formation
- Trial name
- NCT06367881
- Testing
- Alveofact, Budesonide
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Insufficient Breast Milk Syndrome, Premature Birth
Domperidone on the Composition of Preterm Breastmilk Using a Human Milk Mid-infrared Spectroscopy Analyzer
Maintaining milk production in lactating mothers who have delivered prematurely can be a challenge. In these cases, domperidone has been the most commonly used pharmacologic galactagogue.
- Trial name
- DompMilk (NCT06830226)
- Testing
- Test group, Reference group
- Where
- Portugal
- Volunteers
- 81 people
- Sponsor
- Centro Hospitalar de Lisboa Central
Preterm Birth, Obstetric Labor, Premature
Prevention of Preterm Labor in Patients With a Previous Episode of Threatened Preterm Labor With Progesterone
The purpose of this study is to determine if the use of 250 mg of intramuscular progesterone biweekly can reduce the incidence of preterm labor in patients with an episode of threatened preterm labor during the current pregnancy.
- Trial name
- NCT01317225
- Testing
- 17 α hydroxyprogesterone caproate
- Where
- Panama
- Volunteers
- 80 people
- Sponsor
- Saint Thomas Hospital, Panama
Cerebral Oxygenation, Intracranial Haemorrhagia
Measurement of Cerebral Oxygenation Using NIRS Method in the Preterm Infants With Intracranial Haemorrhagia
The aim of the study was investigated the cerebral tissue oxygenation index (c-TOI) measured by near infrared spectroscopy (NIRS)in the preterm infants with intracranial haemorrhagia.
- Trial name
- NCT01266889
- Testing
- device:INVOS 5100
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Prematurity, Dysphagia
Swallowing and Oral Sensory Complaints in Preterm Children
Objective Preterm children face an elevated risk of neurodevelopmental delays and feeding difficulties, necessitating early assessment to support their long-term health.
- Conditions
- Prematurity, Dysphagia, Feeding Disorder of Infancy or Early Childhood
- Trial name
- NCT06881381
- Where
- Turkey (Türkiye)
- Volunteers
- 158 people
- Sponsor
- Medipol University
Preterm Birth, Breastfeeding
Phone Breastfeeding Support for Premature Babies
It was observed that premature babies had the risk of insufficient milk intake and a lower rate of breastfeeding compared to term babies.
- Trial name
- NCT04883866
- Testing
- Telephone Breastfeeding Support Program, Sending a breastfeeding guide for premature babies to the phone of mothers in addition to the routine discharge procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Preterm Labor, Preterm Birth
The Efficacy of Nifedipine in the Management of Preterm Labor
Preterm labor is one of the problems of obstetrics, and is one of the leading cause of neonatal morbidity and mortality. The incidence of preterm birth is around 7 to 9 %.
- Conditions
- Preterm Labor, Preterm Birth, Preterm Labor Without Delivery, Preterm Labor With Preterm Delivery in Third Trimester
- Trial name
- BOG/TH/PTL (NCT04644354)
- Testing
- Nifedipine 10 mg
- Volunteers
- 444 people
- Sponsor
- Ethem Unal, M.D., PhD, Associate Prof of Surgery & Surgic
Preterm Birth, Preterm Premature Rupture of Membrane
Cerclage After Full Dilatation Caesarean Section
CRAFT-OBS: Observational Study; To evaluate subsequent pregnancy risk of preterm birth in women with a history of previous caesarean in established labour.
- Conditions
- Preterm Birth, Preterm Premature Rupture of Membrane, Preterm Spontaneous Labor With Preterm Delivery
- Trial name
- CRAFT (NCT04110704)
- Testing
- Insertion of transvaginal cerclage
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Respiratory Distress Syndrome (Neonatal), Respiratory Distress of Newborn
How Different Levels of CPAP Affect Oxygen Delivery and Lung Expansion in Preterm Infants
With this study, it is expected to learn more about preterm babies on breathing support with nasal continuous positive airway pressure (nCPAP).
- Trial name
- NCT07674953
- Testing
- Effective oxygen delivery and lung expansion measurement
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Arkansas
Growth Disorders, Growth Failure
Is There a Microbiome Associated With Poor Growth in Preterm Infants?
This study evaluates the relationship between growth and stool microbiota in premature infants.
- Conditions
- Growth Disorders, Growth Failure, Prematurity
- Trial name
- NCT03761498
- Testing
- Caloric Requirement
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Texas Southwestern Medical Center
Bronchopulmonary Dysplasia
Cellular Therapy for Extreme Preterm Infants at Risk of Developing Bronchopulmonary Dysplasia
Bronchopulmonary dysplasia (BPD) is a common and chronic lung disease that occurs in preterm infants following ventilator and oxygen therapy and is associated with long-term health consequences.
- Trial name
- NCT04255147
- Testing
- Allogeneic Umbilical Cord Tissue-Derived Mesenchymal Stromal Cells
- Where
- 2 sites in Canada
- Volunteers
- 9 people
- Sponsor
- Ottawa Hospital Research Institute